Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(147 products)
- Cell wall(5 products)
- IL Receptor(113 products)
- IκB/IKK(61 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3035 products of "Immunology and Inflammation"
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BMS-378806
CAS:<p>BMS-378806 (BMS-806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.</p>Formula:C22H22N4O4Purity:99.93%Color and Shape:SolidMolecular weight:406.43AHR-10037
CAS:<p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>Formula:C15H13ClN2O2Purity:98%Color and Shape:SolidMolecular weight:288.73Kamebakaurin
CAS:<p>Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling pathways.</p>Formula:C20H30O5Purity:98.05%Color and Shape:SolidMolecular weight:350.45TMV-IN-9
CAS:<p>TMV-IN-9 (compound A6) is an antiviral agent that exhibits exceptional inactivation effects against Tobacco Mosaic Virus (TMV), with an EC50 of 62.8 μg/mL. It demonstrates strong binding capabilities to the TMV capsid protein, with a binding affinity of 1.862 μM. Moreover, TMV-IN-9 significantly disrupts the integrity of TMV particles, thereby preventing the virus from infecting the host.</p>Formula:C20H20O8Color and Shape:SolidMolecular weight:388.373,4-DAA
CAS:<p>3,4-DAA has anti-inflammatory activity and inhibits EOC20 cell-induced nitric oxide synthase (iNOS) induced by IFN-γ and lipopolysaccharide.</p>Formula:C18H17NO6Purity:98%Color and Shape:SolidMolecular weight:343.33(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one
CAS:<p>(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one is a major mechanism of Sinomenine.</p>Formula:C18H21NO4Purity:97.85%Color and Shape:SoildMolecular weight:315.36Catalase
CAS:<p>Catalase, an enzyme, metabolizes H2O2 and ROS; its expression and localization change significantly in tumors.</p>Purity:≥98%Color and Shape:Small Colorless Crystals Or Powder At Room Temperature Almost Odourless Small Colourless Crystals Or A White Crystalline PowderE3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formula:C21H30O6Purity:99.52%Color and Shape:SolidMolecular weight:378.46Pelubiprofen
CAS:<p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>Formula:C16H18O3Purity:99.69%Color and Shape:SolidMolecular weight:258.31Allopurinol Sodium
CAS:<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Formula:C5H4N4NaOPurity:99.93%Color and Shape:SolidMolecular weight:159.1Keap1-Nrf2-IN-11
CAS:<p>Keap1-Nrf2-IN-11 (6k) inhibits Keap1-Nrf2, KD 0.21 nM; reduces ROS, NO, TNF-α; aids anti-inflammatory research.</p>Formula:C36H43N7O8S2Color and Shape:SolidMolecular weight:765.9COX-2-IN-22
CAS:<p>COX-2-IN-22 inhibits COX-2 (IC50: 8.6μM) and crosses the blood-brain barrier, also affects AChE, BChE, β-Secretase, LOX-5, DPPH.</p>Formula:C29H24O7Color and Shape:SolidMolecular weight:484.5Fc 11a-2
CAS:<p>Fc 11a-2, an oral benzimidazole, potently inhibits NLRP3 inflammasome and caspase-1 to prevent colitis.</p>Formula:C16H16N2Color and Shape:SolidMolecular weight:236.31Anti-inflammatory agent 21
CAS:<p>Compound 9o: orally active, low-toxicity anti-inflammatory; inhibits NO (IC50: 0.76 μM), blocks NF-κB/MAPK, reduces arthritis symptoms.</p>Formula:C24H21FO6Color and Shape:SolidMolecular weight:424.42CD73-IN-9
CAS:<p>CD73-IN-9, a potent inhibitor of CD73, may treat cancer by blocking adenosine production that aids tumor growth and spread.</p>Formula:C14H11F2N5O2Color and Shape:SolidMolecular weight:319.27HSR1304
CAS:<p>HSR1304 (5d) inhibits NFκB, key in diseases like cancer, offering research potential.</p>Formula:C24H21ClN2O3Color and Shape:SolidMolecular weight:420.89STING Agonist C11
CAS:<p>STING agonist C11 activates STING, induces type I IFN in cells, phosphorylates IRF3, and lowers various viral titers via STING/IFNAR pathway.</p>Formula:C19H18N4O3SColor and Shape:SolidMolecular weight:382.44Carboxyamidotriazole
CAS:<p>Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways.</p>Formula:C17H12Cl3N5O2Purity:98%Color and Shape:SolidMolecular weight:424.67BCX 1470
CAS:<p>BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.</p>Formula:C14H10N2O2S2Purity:98%Color and Shape:SolidMolecular weight:302.37AP-1/NF-κB activation inhibitor 1
CAS:<p>AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal</p>Formula:C13H11F3N4O4Purity:99.52% - 99.91%Color and Shape:SolidMolecular weight:344.25CK-119
CAS:<p>CK-119 inhibits IL-1, blocking corneal/conjunctival cell growth by halting DNA/RNA synthesis.</p>Formula:C21H23ClN4O5Color and Shape:SolidMolecular weight:446.88U-83836E
CAS:<p>U-83836E (lazaroid ) Possesses neuroprotective activity and anti-tumor activity, inhibits tumor necrosis factor and reverses endotoxin-induced shock.</p>Formula:C30H46Cl2N6O2Purity:99.33%Color and Shape:SolidMolecular weight:593.63MIF-IN-3
CAS:<p>MIF-IN-3 inhibits MIF; useful in immunoinflammation research. (WO2021258272A1, compound 31)</p>Formula:C20H20N4O5SColor and Shape:SolidMolecular weight:428.46COX-2-IN-28
CAS:<p>COX-2-IN-28 is a potent and selective COX-2 inhibitor capable of acting on COX-2 (IC50: 0.054 μM), 15-LOX (IC50: 2.14 μM) and COX-1 (IC50: 13.21 μM).</p>Formula:C30H27N7S3Color and Shape:SolidMolecular weight:581.78BBS-4
CAS:<p>BBS-4 inhibits NOS2 dimerization (IC50: 0.49 nM), guarding mice against sepsis-related heart issues.</p>Formula:C22H24N6O3Color and Shape:SolidMolecular weight:420.46NBC 19
CAS:<p>Potent NLRP3 inflammasome inhibitor (IC50 = 60-80 nM). Inhibits nigericin- and ATP-induced IL-1β release.</p>Formula:C24H26BCl3N2O2Color and Shape:SolidMolecular weight:491.65MIP-1095
CAS:<p>MIP-1095 is the prostate-specific membrane antigen inhibitor.</p>Formula:C19H25IN4O8Purity:98%Color and Shape:SolidMolecular weight:564.33Naproxcinod
CAS:<p>Naproxcinod is a derivative of naproxen, analgesic and anti-inflammatory, a COX-inhibitory nitric oxide donor (CINOD), osteoarthritis and inflammatory.</p>Formula:C18H21NO6Color and Shape:SolidMolecular weight:347.36NOC-5
CAS:<p>NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.</p>Formula:C6H16N4O2Purity:98%Color and Shape:SolidMolecular weight:176.22Stigmane B
<p>Stigmane B activates Nrf2, decreases apoptosis and ROS, boosts antioxidants, and is neuroprotective.</p>Formula:C21H30O4Color and Shape:SolidMolecular weight:346.46Dibenzo(a,i)pyrene
CAS:<p>Dibenzo(a, i)pyrene is a polycyclic aromatic hydrocarbon with potent carcinogenic activity.</p>Formula:C24H14Color and Shape:Greenish-Yellow Needles Prisms Or Lamellae Dibenz[A I]Pyrene Is A Colorless Solid Water InsolubleMolecular weight:302.37Leptospermone
CAS:<p>Leptospermone is an essential oil from Leptospermum scoparium (manuka oil).</p>Formula:C15H22O4Color and Shape:SolidMolecular weight:266.33NIC-0102
CAS:<p>NIC-0102 is an orally active proteasome inhibitor (pIC50:7.55) that exhibits specific inhibition of NLRP3 inflammatory vesicle activation. Inhibitory effect.</p>Formula:C21H25BF2N2O4Color and Shape:SolidMolecular weight:418.24Nexinhib20
CAS:<p>Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2.</p>Formula:C15H16N4O3Purity:99.89%Color and Shape:SolidMolecular weight:300.31NOS1-IN-1
CAS:<p>NOS1-IN-1: selective, potent nNOS inhibitor (Ki: 120 nM), less effective on eNOS/iNOS, for neurological disorder research.</p>Formula:C14H24F9N7O8Purity:99.7%Color and Shape:SolidMolecular weight:589.37FK-330 dihydrate
CAS:<p>FK-330 dihydrate (FR-260330 dihydrate), as a NOS inhibitor, prevents tissue damage caused by ischemia and reperfusion. Cost-effective and quality-assured.</p>Formula:C29H32ClF3N6O6Purity:99.52% - 99.98%Color and Shape:SolidMolecular weight:653.05Feprazone
CAS:<p>Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.</p>Formula:C20H20N2O2Purity:99.6% - 99.89%Color and Shape:SolidMolecular weight:320.3912(R)-HETE
CAS:<p>12(R)-HETE made in invertebrates by lipoxygenation, in mammals by 12(R)-LOs/CYP450. Mainly proinflammatory, attracts leukocytes, reduces rabbit eye pressure.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47DPP-4 inhibitor 3
CAS:<p>DPP-4 inhibitor 3 is a powerful DPP-IV blocker with 0.75 nM IC50, boasting antioxidant and insulinotropic effects.</p>Formula:C19H22N6O2Color and Shape:SolidMolecular weight:366.42Imupedone
CAS:<p>Imupedone (LF 1695) is a synthetic immunomodulator that increases the proliferative response of lymphocytes to mitogens, antigens and allogeneic cells.</p>Formula:C19H21ClN2OPurity:99.53%Color and Shape:SolidMolecular weight:328.84CID-2858522
CAS:<p>CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).</p>Formula:C28H39N3O3Purity:96.12%Color and Shape:SolidMolecular weight:465.63Naproxen glucuronide
CAS:<p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>Formula:C20H22O9Color and Shape:SolidMolecular weight:406.38CHD-5
CAS:<p>CHD-5 is a selective antagonist of the aryl hydrocarbon receptor (AhR).</p>Formula:C19H17N3O2Color and Shape:SolidMolecular weight:319.36IRAK4-IN-22
CAS:<p>IRAK4-IN-22: oral IRAK4 inhibitor, IC50: IRAK4-3nM, TAK1-17nM, disrupts IL-23, targets autoimmune diseases.</p>Formula:C28H28FN7O2Color and Shape:SolidMolecular weight:513.57Enflicoxib
CAS:<p>Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.</p>Formula:C16H12F5N3O2SPurity:99.88%Color and Shape:SolidMolecular weight:405.34Galectin-3-IN-1
CAS:<p>Galectin-3-IN-1 is a potent Gal-3 inhibitor, key in cancer-related metabolic processes.</p>Formula:C18H26O10SColor and Shape:SolidMolecular weight:434.46Tilarginine citrate
CAS:<p>Tilarginine citrate is a competitive nitric oxide synthetase inhibitor.</p>Formula:C13H24N4O9Purity:98%Color and Shape:SolidMolecular weight:380.354Ro 106-9920
CAS:<p>Inhibitor of NF-κB activation</p>Formula:C10H7N5OSPurity:98%Color and Shape:SolidMolecular weight:245.26HE 3286
CAS:<p>Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.</p>Formula:C21H30O3Color and Shape:SolidMolecular weight:330.46ROS inducer 3
CAS:<p>ROS inducer 3 is a ROS inducer used as a bactericide in the study of resistant plant bacterial diseases, inhibiting Streptomyces.</p>Formula:C22H22F3N3OPurity:99.88%Color and Shape:SolidMolecular weight:401.43ROS inducer 2
CAS:<p>ROS inducer 2 is a reactive oxygen species (ROS) inducer with antibacterial activity, inhibiting Axonobacter species.</p>Formula:C23H24F3N3OPurity:99.53% - 99.97%Color and Shape:SolidMolecular weight:415.45COX-2-IN-21
CAS:<p>COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.</p>Formula:C21H22N6O4Color and Shape:SolidMolecular weight:422.44IND24
CAS:<p>IND24 has anti-prion activity and can be used to study neurodegenerative diseases.</p>Formula:C21H17N3SPurity:99.64%Color and Shape:SolidMolecular weight:343.44NF-κB-IN-3
CAS:<p>NF-κB-IN-3 (Compound 2) is an NF-κB inhibitor (IC50: 0.70 μM) and can be used as an anti-tumour agent.</p>Formula:C24H18ClF3N2O2Color and Shape:SolidMolecular weight:458.86AChE/Nrf2 modulator 1
CAS:<p>AChE/Nrf2 modulator 1: oral, targets AChE/Nrf2, IC50s: 0.07 μM (eeAChE), 0.38 μM (hAChE); for Alzheimer's research.</p>Formula:C27H27FN4O2Color and Shape:SolidMolecular weight:458.53Nrf2 activator-5
CAS:<p>Nrf2 activator-5 combats oxidative stress and inflammation in microglia, with potent antioxidant effects.</p>Formula:C25H30Cl2O6Color and Shape:SolidMolecular weight:497.41Ferric citrate
CAS:<p>Ferric citrate as a source of iron used in cell culture applications can provide iron with a less toxic form compared to free iron salts.</p>Formula:C6H8FeO7Color and Shape:Limit Its Spread To The Environment It Is Used In Medicine In Making Blueprints And As A FeedMolecular weight:247.968Antimicrobial agent-2
CAS:<p>Compound V-a: broad-spectrum, low-toxicity antimicrobial with no resistance, high bioavailability, damages membranes, targets MRSA (MIC 1μg/mL).</p>Formula:C16H14N2O4SColor and Shape:SolidMolecular weight:330.36iNOs-IN-3
CAS:<p>iNOs-IN-3: oral iNOS inhibitor, IC50 = 3.342 μM, anti-inflammatory, for LPS-induced ALI study.</p>Formula:C27H24N2O5SColor and Shape:SolidMolecular weight:488.55TNF-α-IN-18
CAS:<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Formula:C16H7ClF2O4Purity:99.77%Color and Shape:SolidMolecular weight:336.6710-Cl-BBQ
CAS:<p>10-Cl-BBQ is a ligand of aryl hydrocarbon receptor (AhR).</p>Formula:C18H9ClN2OColor and Shape:SolidMolecular weight:304.73Ophthalmic acid
CAS:<p>Ophthalmic acid is a glutathione analog in which cysteine is substituted by L-aminobutyrate.</p>Formula:C11H19N3O6Color and Shape:SolidMolecular weight:289.29Antiviral agent 14
CAS:<p>Antiviral agent 14 is an antiviral agent that inhibits tobacco mosaic virus (TMV) (EC50: 135.5 μg/mL), and cucumber mosaic virus (CMV) (EC50: 178.6 μg/mL).</p>Formula:C24H26O7Color and Shape:SolidMolecular weight:426.46NXPZ-2
CAS:<p>NXPZ-2, an oral Keap1-Nrf2 PPI inhibitor (Ki: 95 nM, EC50: 120-170 nM), may improve cognition and neuron health in AD.</p>Formula:C27H27N5O7S2Color and Shape:SolidMolecular weight:597.66APHS
CAS:<p>APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.</p>Formula:C15H18O2SColor and Shape:SolidMolecular weight:262.37S-Isopropylisothiourea hydrobromide
CAS:<p>S-Isopropylisothiourea hydrobromide is an iNOS inhibitor.</p>Formula:C4H11BrN2SPurity:98%Color and Shape:SolidMolecular weight:199.11Keap1-Nrf2-IN-12
CAS:<p>eap1-Nrf2-IN-12 is a potent inhibitor of Keap1-Nrf2 (IC50: 2.30 μM). eap1-Nrf2-IN-12 is metabolically stable in human liver microsomes.</p>Formula:C26H28N2O10S2Color and Shape:SolidMolecular weight:592.64Piroxicam cinnamate
CAS:<p>Cinnoxicam is a COX inhibitor used for bone/joint inflammation, rheumatic issues, and varicocele-related oligospermia.</p>Formula:C24H19N3O5SColor and Shape:SolidMolecular weight:461.49IT-901
CAS:<p>IT-901: Oral NF-κB c-Rel inhibitor, IC50 0.1 µM. Blocks c-Rel/DNA binding, IC50 3 µM. Antitumor naphthalene derivative for lymphoma/myeloma therapy.</p>Formula:C17H14N2O4SPurity:98.06%Color and Shape:SolidMolecular weight:342.37P2X7-IN-2
CAS:<p>P2X7-IN-2 is a P2X7 receptor blocker, halts IL-Iβ release (IC50: 0.01 nM), researched for autoimmunity and heart issues.</p>Formula:C22H21F4N3O2Color and Shape:SolidMolecular weight:435.41PT4
CAS:<p>PT4: treats CL, disrupts parasite mitochondria, kills Leishmania spp., IC50- L. amazonensis 125.18 μM, L. braziliensis 233.18 μM, anti-inflammatory.</p>Formula:C18H14N4O2Color and Shape:SolidMolecular weight:318.33COX-2/5-LOX-IN-2
CAS:<p>COX-2/5-LOX-IN-2, a benzothiophen derivative, inhibits COX-1, COX-2, 5-LOX with IC50s of 5.40, 0.01, 1.78 μM. More effective than Celecoxib, Indomethacin.</p>Formula:C18H13N3O4S2Color and Shape:SolidMolecular weight:399.44DMX-129
CAS:<p>DMX-129 is a chemical compound acting as an inhibitor for both ΙΚΚε and TBK-1, demonstrating efficacy with IC50 values of below 30 nM for each [1].</p>Formula:C19H17FN8Color and Shape:SolidMolecular weight:376.39CAY10589
CAS:<p>CAY10589 is an mPGES-1 inhibitor.</p>Formula:C25H28ClN3O2SColor and Shape:SolidMolecular weight:470.03COX-2-IN-19
CAS:<p>COX-2-IN-19, a potent COX-2 inhibitor, IC50 of 1.76 μM, has strong anti-inflammatory effects in vivo.</p>Formula:C18H18N4O2SColor and Shape:SolidMolecular weight:354.43HPN-01
CAS:<p>HPN-01 (IKK inhibitor XII) is an IKK inhibitor that inhibits IKK-α and IKK-ε, prolongs the lifespan of mice, and can be used to study immune disorders.</p>Formula:C19H16ClN3O3SPurity:98.07% - 98.17%Color and Shape:SolidMolecular weight:401.87RIP2 Kinase Inhibitor 3
CAS:<p>RIP2 Kinase Inhibitor 3 is a potent and selective inhibitor of RIP2 with an IC50 of 1 nM.</p>Formula:C19H24N4O3SPurity:99.32% - 99.52%Color and Shape:SolidMolecular weight:388.48RI-962
CAS:<p>RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.</p>Formula:C28H28N6O2Purity:99.39%Color and Shape:SoildMolecular weight:480.56TLR7/8 agonist 4
CAS:<p>TLR7/8 agonist 4 (compound 41) is a potent agonist of TLR7/8 with anti-cancer activity [1].</p>Formula:C18H24N6Color and Shape:SolidMolecular weight:324.42COX-2-IN-24
CAS:<p>COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.</p>Formula:C24H24BrN5O3S2Color and Shape:SolidMolecular weight:574.51PPM-18
CAS:<p>PPM-18 (NSC 73233), a potent anti-inflammatory, inhibits iNOS and NF-κB binding; also suppresses bladder cancer cell growth.</p>Formula:C17H11NO3Color and Shape:SolidMolecular weight:277.27IRAK4-IN-13
CAS:<p>IRAK4-IN-13 (compound 21) is a potent IRAK4 inhibitor, IC50 0.6 nM, with high HLM clearance at 96 μL/min/mg.</p>Formula:C24H27N9OColor and Shape:SolidMolecular weight:457.53NF-κB/PON1-IN-1
CAS:<p>NF-κB/PON1-IN-1 (Compound 16) is an NF-κB/PON1 pathway inhibitor with antioxidant activity (IC50: 45.76 μM) and hepatoprotective activity.</p>Formula:C20H16N6O4S2Color and Shape:SolidMolecular weight:468.51COX-2-IN-23
CAS:<p>COX-2-IN-23 selectively inhibits COX-2 (IC50=0.28μM), weakly affects COX-1 (IC50=20.14μM), and has anti-inflammatory and low ulcerogenic properties.</p>Formula:C24H25N5O3S2Color and Shape:SolidMolecular weight:495.62IFN α-IFNAR-IN-1
CAS:<p>Nonpeptidic IFN-α/IFNAR blocker, halts MVA-triggered BM-pDC IFN-α response; IC50: 2-8 μM.</p>Formula:C18H17NSPurity:98%Color and Shape:SolidMolecular weight:279.4COX-1/2-IN-3
CAS:<p>COX-1/2-IN-3 (Compound 7a) is a dual inhibitor of COX-1 and COX-2. COX-1/2-IN-3 has anti-inflammatory activity with low toxicity [1].</p>Formula:C14H8N2O8Color and Shape:SolidMolecular weight:332.22Asperbisabolane L
<p>Asperbisabolane L, a sesquiterpenoid, combats inflammation by blocking NF-κB signaling and NO in BV-2 cells.</p>Formula:C12H14O3Color and Shape:SolidMolecular weight:206.24MIF-IN-1
CAS:<p>MIF-IN-1 (compound 14) inhibits MIF, a cytokine linked to diseases, with pIC50 of 6.87.</p>Formula:C15H13N3O5Color and Shape:SolidMolecular weight:315.28Isofezolac
CAS:<p>Isofezolac (LM 22070), a NSAID, inhibits prostaglandin-synthetase, offering powerful anti-inflammatory and antipyretic effects.</p>Formula:C23H18N2O2Color and Shape:SolidMolecular weight:354.4MSU38225
CAS:<p>MSU38225, an Nrf-2 inhibitor, elevates reactive oxygen species (ROS) levels and suppresses the proliferation of human lung cancer cells.</p>Formula:C21H19N3Color and Shape:SolidMolecular weight:313.43-Bromo-7-nitroindazole
CAS:<p>3-Bromo-7-nitroindazole specifically inhibits nNOS, impacting NO synthesis in brain/body.</p>Formula:C7H4BrN3O2Purity:98.2%Color and Shape:Yellowish SolidMolecular weight:242.03CU-76
CAS:<p>CU-76 inhibits cGAS (IC50 = 0.24 μM) affecting DNA-induced IFN-β production, not RIG-I-MAVS pathway, in THP-1 cells.</p>Formula:C11H8F2IN5O2Color and Shape:SolidMolecular weight:407.11AN3485 Hydrochloride
CAS:<p>AN3485 Hydrochloride is an anti-inflammatory agent and a TLRs inhibitor, reducing ear swelling induced by PMA.</p>Formula:C14H14BCl2NO3Purity:98.34%Color and Shape:SolidMolecular weight:325.98Oxyphenbutazone monohydrate
CAS:<p>Oxyphenbutazone monohydrate: Phenylbutazone derivative, anti-inflammatory, non-selective COX inhibitor, kills dormant M. tuberculosis.</p>Formula:C19H22N2O4Color and Shape:SolidMolecular weight:342.39Bay 65-1942 free base
CAS:<p>Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.</p>Formula:C22H25N3O4Purity:98%Color and Shape:SolidMolecular weight:395.45Z-VRPR-FMK
CAS:<p>Z-VRPR-FMK: irreversible MALT1 inhibitor, halts growth/invasion of diffused B-cell lymphoma by blocking NF-κB activation and MMP expression.</p>Formula:C31H49FN10O6Color and Shape:SolidMolecular weight:676.78COX-1/2-IN-1
CAS:<p>"COX-1/2-IN-2: Strong dual inhibitor of COX-1 (IC50 = 13.9 μM) and COX-2 (IC50 = 6.4 μM)."</p>Formula:C15H10BrClN2OColor and Shape:SolidMolecular weight:349.61β-Nor-lapachone
CAS:<p>β-Nor-lapachone is an antibiofilm agent of Candida glabrata.</p>Formula:C14H12O3Color and Shape:SolidMolecular weight:228.24Keap1-Nrf2-IN-14
CAS:<p>Keap1-Nrf2-IN-14, a KEAP1-NRF2 inhibitor (IC50: 75 nM, Kd: 24 nM), boosts NRF2 gene expression, antioxidative and anti-inflammatory response.</p>Formula:C30H29NO8SColor and Shape:SolidMolecular weight:563.62COX-2/sEH-IN-1
CAS:<p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>Formula:C23H18F3N5O3SColor and Shape:SolidMolecular weight:501.48Veledimex (S enantiomer)
CAS:<p>Veledimex S is the oral S enantiomer of a gene therapy promoter activator and CYP3A4/5 inhibitor.</p>Formula:C27H38N2O3Purity:98%Color and Shape:SolidMolecular weight:438.6PNRI-299
CAS:<p>PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).</p>Formula:C21H15N5O4Purity:98%Color and Shape:SolidMolecular weight:401.37CD73-IN-1
CAS:<p>CD73-IN-1 is a CD73 inhibitor with anticancer activity.</p>Formula:C18H17N3O4SPurity:99.46% - 99.46%Color and Shape:SolidMolecular weight:371.41TMV-IN-1
CAS:<p>TMV-IN-1: a chalcone inhibits TMV with EC50s of 70.7 and 60.8 μg/mL, applicable in infection and tumor studies.</p>Formula:C28H26O4Color and Shape:SolidMolecular weight:426.5TLR7/8 agonist 6
CAS:<p>Compound 4: Imidazoquinoline, potent TLR7/8 agonist, IC50: 0.18μM (TLR7), 5.34μM (TLR8).</p>Formula:C24H27N5O2Color and Shape:SolidMolecular weight:417.5Tin(IV) mesoporphyrin IX dichloride
CAS:<p>Tin(IV) mesoporphyrin IX dichloride (Stannsoporfin) is an effective heme oxygenase (HO) inhibitor used for the treatment of hyperbilirubinemia.</p>Formula:C34H36Cl2N4O4SnPurity:99.82%Color and Shape:SolidMolecular weight:754.29LY 178002
CAS:<p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>Formula:C18H25NO2SPurity:98%Color and Shape:SolidMolecular weight:319.46APC-0576
CAS:<p>APC-0576, an (S,S)-isomer, blocks NF-kappaB gene activation and may reduce inflammation in human cells.</p>Formula:C23H27N3O3Color and Shape:SolidMolecular weight:393.48ADU-S100 ammonium salt
CAS:<p>ADU-S100 ammonium salt is an activator of stimulator of interferon genes (STING).Cost-effective and quality-assured.</p>Formula:C20H30N12O10P2S2Purity:98%Color and Shape:SolidMolecular weight:724.6COX-2-IN-20
CAS:<p>COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].</p>Formula:C11H9ClFN3O2Color and Shape:SolidMolecular weight:269.66MitoTEMPOL
CAS:<p>MitoTEMPOL is a mitochondria-targeted antioxidant that prevents septal dysfunction by reversing sepsis-induced decreases in mitochondrial function.</p>Formula:C32H42BrNO2PColor and Shape:SolidMolecular weight:583.56NLRP3-IN-13
CAS:<p>NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.</p>Formula:C19H15N3O3SPurity:99.16%Color and Shape:SolidMolecular weight:365.41C5aR-IN-2
CAS:<p>C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.</p>Formula:C36H40FN5O2Color and Shape:SolidMolecular weight:593.73Keap1-Nrf2-IN-13
CAS:<p>Keap1-Nrf2-IN-13 is a PPI inhibitor (IC50: 0.15 μM) that binds Keap1 strongly, useful for oxidative stress and inflammation research.</p>Formula:C28H32N2O10S2Color and Shape:SolidMolecular weight:620.69c-di-AMP
CAS:<p>c-di-AMP (Cyclic diadenylate) is a STING agonist. It binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway.</p>Formula:C20H24N10O12P2Purity:98%Color and Shape:SolidMolecular weight:658.41BC12-4
CAS:<p>BC12-4 is a novel potent inhibitor of IL-2 secretion, it has potent immunomodulatory activity.</p>Formula:C19H14N2O3Color and Shape:SolidMolecular weight:318.33STING modulator-4
CAS:<p>STING modulator-4: competitive, Ki=0.0933 μM (R232H STING), EC50 >10 μM (p-IRF3, THP-1 cells).</p>Formula:C17H18N8OColor and Shape:SolidMolecular weight:350.38L-Kynurenine sulfate
CAS:<p>L-Kynurenine sulfate activates AHR, leading naive T cells to anti-inflammatory Treg phenotype.</p>Formula:C10H14N2O7SColor and Shape:SolidMolecular weight:306.29GCPII-IN-1 TFA
CAS:<p>GCPII-IN-1 TFA (compound 2) is an inhibitor scaffold for glutamate carboxypeptidase II (GCPII, PSMA) with a Ki of 44.3±2.4 nM for use in prostate cancer.</p>Formula:C14H22F3N3O9Color and Shape:SoildMolecular weight:433.34OPC-163493
CAS:<p>OPC-163493 is an orally active, liver-targeted mitochondrial uncoupling agent that diminishes Δψ (delta psi) and mitochondrial ROS (reactive oxygen species)</p>Formula:C14H8F3N5SPurity:98%Color and Shape:SolidMolecular weight:335.31HPGDS inhibitor 3
CAS:<p>HPGDS inhibitor 3: oral, potent (IC50=9.4 nM; EC50=42 nM), selective, no CNS toxicity, good pharmacokinetics, anti-inflammatory.</p>Formula:C21H27N3O2Color and Shape:SolidMolecular weight:353.46IRAK4-IN-17
CAS:<p>IRAK4-IN-17 is a potent IRAK4 inhibitor with a 1.3 nM IC50, key for DLBCL research.</p>Formula:C17H20F2N8OColor and Shape:SolidMolecular weight:390.39T-5342126
CAS:<p>T-5342126: TLR4 antagonist, lowers LPS-induced NO in cells (IC50=27.8 μM) & cytokines in blood, cuts ethanol intake & Iba1 in mice.</p>Formula:C25H32ClN3O3Color and Shape:SolidMolecular weight:457.99CAY10575
CAS:<p>CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of inflammatory and endocrine diseases.</p>Formula:C22H21N3O6S2Color and Shape:SolidMolecular weight:487.55Nω-Propyl-L-arginine hydrochloride
CAS:<p>Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo.</p>Formula:C9H21ClN4O2Color and Shape:SolidMolecular weight:252.74NLRP3-IN-16
CAS:<p>NLRP3-IN-16: potent NLRP3 inflammasome inhibitor; IC50=0.065μM; curbs IL-1β; used in inflammation studies.</p>Formula:C25H25NO5Purity:98%Color and Shape:SolidMolecular weight:419.478A8
CAS:<p>8A8 is a potent NO inhibitor with proinflammatory factor properties, exhibiting an IC50 of 4.7 μM.</p>Formula:C36H37BrClN5O9Purity:98%Color and Shape:SolidMolecular weight:799.06IMD-biphenylB
CAS:<p>IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.</p>Formula:C35H33N5O3Purity:98%Color and Shape:SolidMolecular weight:571.67STING agonist-30
CAS:<p>STING agonist-30 is a STING agonist that stimulates STING-dependent immune activation and inhibits HSV, rotavirus and SARS-CoV-2.</p>Formula:C15H16N4O8Purity:98.80%Color and Shape:SolidMolecular weight:380.31CD38 inhibitor 3
CAS:<p>CD38 Inhibitor 3 (compound 1), with an IC50 of 11 nM, is a potent agent that enhances mitochondrial biogenesis, diminishes lactate levels, and augments both NAD</p>Formula:C16H14F3N7O3Purity:98%Color and Shape:SolidMolecular weight:409.32NLRP3-IN-20
CAS:<p>NLRP3-IN-20 (compound 11) is an orally administered inhibitor targeting the NLRP3 inflammasome, exhibiting potent inhibition with an IC50 of 25 nM against IL-1β</p>Formula:C22H27N3O3SPurity:98%Color and Shape:SolidMolecular weight:413.53iNOS inhibitor-10
CAS:<p>iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1].</p>Formula:C22H23N3O2SPurity:98%Color and Shape:SolidMolecular weight:393.5COX-2-IN-32
CAS:<p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>Formula:C25H24O6Purity:98%Color and Shape:SolidMolecular weight:420.45SZM679
<p>SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, Tau phosphorylation in AD research.</p>Formula:C27H18F5N3O5SPurity:98%Color and Shape:SolidMolecular weight:591.51Eltrombopag methyl ester
CAS:<p>Eltrombopag methyl ester, a Tpo receptor agonist derivative, boosts platelet production for thrombocytopenia research.</p>Formula:C26H24N4O4Color and Shape:SolidMolecular weight:456.49IMD-catechol
CAS:<p>IMD-catechol: an imidazoquinolinone-based dimer with NF-κB activity; improves CT26 cancer treatment, low toxicity.</p>Formula:C31H34N6O3Purity:98%Color and Shape:SolidMolecular weight:538.64NLRP3-IN-19
CAS:<p>JT001 (NLRP3-IN-19) is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome.</p>Formula:C19H22N4O4SPurity:98%Color and Shape:SolidMolecular weight:402.47NF-κB-IN-8
CAS:<p>NF-κB-IN-8 is a competitive antagonist of LPS for MD-2 binding, and it impedes the expression of inflammatory factors by engaging MD-2.</p>Formula:C24H21N3O3Purity:98%Color and Shape:SolidMolecular weight:399.44IMD-biphenylA
CAS:<p>IMD-biphenylA, a novel imidazoquinolinone-based dimer, functions as an NF-κB immunomodulator and enhances the adjuvant properties of small molecule immune</p>Formula:C35H33N5O2Purity:98%Color and Shape:SolidMolecular weight:555.67NF-κB-IN-11
CAS:<p>NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and the nuclear translocation of NF-κB.</p>Formula:C19H18O5Purity:98%Color and Shape:SolidMolecular weight:326.34Nrf2 activator-4
CAS:<p>Nrf2 activator-4 is an Nrf2 activator for the treatment of fatty liver disease associated with metabolic dysfunction in humans.</p>Formula:C23H24ClF3N2O3Purity:98.53%Color and Shape:SolidMolecular weight:468.9Cyclic-di-GMP diammonium
CAS:<p>C-di-GMP diammonium activates STING, regulates biofilms, motility, and virulence in bacteria.</p>Formula:C20H30N12O14P2Color and Shape:SolidMolecular weight:724.47CL264
CAS:<p>CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.</p>Formula:C19H23N7O4Purity:98.01%Color and Shape:SolidMolecular weight:413.43Tyrosinase-IN-12
CAS:<p>Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) is a potent non-competitive tyrosinase inhibitor with an IC50 of 49.33 ± 2.64 µM and a Ki of 31.25 ± 0.25</p>Formula:C16H12ClN3SPurity:99.2%Color and Shape:SoildMolecular weight:313.8NOS-IN-3
CAS:<p>NOS-IN-3: potent, selective iNOS inhibitor; IC50 of 4.6 µM; spares eNOS; low toxicity; potential for septic shock treatment.</p>Formula:C10H15N3OColor and Shape:SolidMolecular weight:193.25Isoandrographolide
CAS:<p>Isoandrographolide induces cell differentiation, protects the liver, blocks NLRP3, and reduces silicosis in mice.</p>Formula:C20H30O5Color and Shape:SolidMolecular weight:350.45AN-3485
CAS:<p>AN-3485 is a Toll-Like Receptor(TLR) inhibitor (IC50s: 18 to 580 nM).</p>Formula:C14H13BClNO3Color and Shape:SolidMolecular weight:289.52PHA-408
CAS:<p>PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2.</p>Formula:C29H27ClFN7O2Purity:98%Color and Shape:SolidMolecular weight:560.02STING Agonist 1a
CAS:<p>STING agonist 1a activates STING, induces IRF-SEAP, IFN-β, IL-6, CXCL10 (EC50=16.77 µM); effects reversed by STING KO/inhibitor H-151.</p>Formula:C19H11Cl2N5OColor and Shape:SolidMolecular weight:396.23BI605906
CAS:<p>BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.</p>Formula:C17H22F2N4O3S2Purity:97.14%Color and Shape:SolidMolecular weight:432.51DHMEQ racemate
CAS:<p>DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.</p>Formula:C13H11NO5Purity:98%Color and Shape:SolidMolecular weight:261.23SNAP 398299
CAS:<p>SNAP 398299 is a Glycopeptide Receptor Type 3 (Gal3) antagonist with anxiolytic and antidepressant-like effects and is used in the study of mood disorders.</p>Formula:C27H24F3N3O2Purity:97.16%Color and Shape:SolidMolecular weight:479.49(+)-DHMEQ
CAS:<p>(+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.</p>Formula:C13H11NO5Color and Shape:SolidMolecular weight:261.23COX-2-IN-16
CAS:<p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>Formula:C19H12BrN3O2Color and Shape:SolidMolecular weight:394.22QD-394
CAS:<p>QD-394 promotes ROS, impairs GSH/GSSG ratio, and is cytotoxic to pancreatic cancer cells, with synergy with napabucasin.</p>Formula:C19H19N5O2Color and Shape:SolidMolecular weight:349.39Phortress
CAS:<p>Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor</p>Formula:C20H25Cl2FN4OSPurity:99.89%Color and Shape:SolidMolecular weight:459.41NLRP3 antagonist 1
CAS:<p>Potential cancer research drug, NLRP3 antagonist 1, targets immune response in macrophages, neutrophils.</p>Formula:C16H18N6OColor and Shape:SolidMolecular weight:310.35AHR antagonist 5
CAS:<p>Potent, oral AHR blocker from WO2018195397; IC50 < 0.5μM; hinders tumor growth with anti-PD-1.</p>Formula:C25H27Cl3FN7Purity:98%Color and Shape:SolidMolecular weight:550.89KIN1400
CAS:<p>KIN1400 activates IRF3, boosts antiviral immunity, stimulates IFNbeta, and inhibits WNV, DV, and HCV.</p>Formula:C24H17F2N3O2SPurity:98%Color and Shape:SolidMolecular weight:449.47Tilarginine
CAS:<p>Tilarginine is a nitric oxide synthetase competitive inhibitor.</p>Formula:C7H16N4O2Purity:98%Color and Shape:SolidMolecular weight:188.23ARV-393
CAS:<p>ARV-393 is a PROTAC degrader targeting BCL6 orally available. ubiquitin proteasome for diffuse large b-cell lymphoma (DLBCL) and non-Hodgkin's lymphoma (NHL)</p>Formula:C46H53ClFN9O7Purity:99.96%Color and Shape:SoildMolecular weight:898.42DDX3-IN-2
CAS:<p>DDX3-IN-2 is a potent DDX3 inhibitor with an IC50 of 0.3 μM and shows broad antiviral effects, including against HIV resistance.</p>Formula:C20H23N5OColor and Shape:SolidMolecular weight:349.43TRAF-STOP inhibitor 6877002
CAS:<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Formula:C17H17NOPurity:99.76%Color and Shape:SolidMolecular weight:251.32MIF-IN-2
CAS:<p>MIF-IN-2 is a MIF inhibitor with anticancer activity for the study of cancer and autoimmune diseases.</p>Formula:C14H10ClN3O4Purity:98.55%Color and Shape:SolidMolecular weight:319.7TBK1/IKKε-IN-4
CAS:<p>TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM</p>Formula:C28H35N7O4Color and Shape:SolidMolecular weight:533.62UC-781
CAS:<p>UC-781, a potent NNRTI, inhibits HIV-1 with a C50 of 5 nM and is stable across pH and temperatures.</p>Formula:C17H18ClNO2SPurity:92.17%Color and Shape:SolidMolecular weight:335.85DSR-6434
CAS:<p>DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.</p>Formula:C19H28N8O2Purity:99.78%Color and Shape:SolidMolecular weight:400.48NRP1 antagonist 2
CAS:<p>NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.</p>Formula:C20H17ClN6OS2Color and Shape:SolidMolecular weight:456.97OXSI-2
CAS:<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Formula:C18H15N3O3SPurity:98%Color and Shape:Dark Orange SolidMolecular weight:353.39Thiazolinobutazone
CAS:<p>Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.</p>Formula:C22H26N4O2SColor and Shape:SolidMolecular weight:410.53CB2 modulator 1
CAS:<p>CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.</p>Formula:C18H19F3N4O2Purity:99.6%Color and Shape:SolidMolecular weight:380.36COX/5-LO-IN-1
CAS:<p>COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.</p>Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.37N-α-Tosyl-L-lysine chloromethyl ketone hydrochloride
CAS:<p>N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride inhibits trypsin-like proteases and IFN-γ activities.</p>Formula:C14H22Cl2N2O3SPurity:97.44%Color and Shape:PowderMolecular weight:369.31COX-2-IN-14
CAS:<p>COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.</p>Formula:C18H18N4O6Color and Shape:SolidMolecular weight:386.364Hetrombopag
CAS:<p>Hetrombopag: potent thrombopoietin receptor agonist, well tolerated, safe, promising for immune thrombocytopenia research.</p>Formula:C25H22N4O5Color and Shape:SolidMolecular weight:458.47Ppc-1
CAS:<p>Ppc-1 inhibits Porphyromonas gingivalis, uncouples mitochondria, and blocks IL-2, with anti-obesity, antibacterial, anti-inflammatory effects.</p>Formula:C21H25NO4Purity:98%Color and Shape:SolidMolecular weight:355.43S-MTC
CAS:<p>S-MTC is a selective inhibitor of type I nitric oxide synthase.</p>Formula:C7H15N3O2SPurity:98%Color and Shape:Off-White Powder / White SolidMolecular weight:205.28Nrf2-Activator-12G
CAS:<p>Nrf2-Activator-12G is a potent Nrf-2 activator.</p>Formula:C15H13ClO3SPurity:98%Color and Shape:SolidMolecular weight:308.78(-)-Ibuprofenamide
CAS:<p>(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.</p>Formula:C13H19NOPurity:98%Color and Shape:SolidMolecular weight:205.3MALT1-IN-8
CAS:<p>MALT1-IN-8: potent MALT1 inhibitor, IC50=2 nM; hinders OCI-LY3 cells, IC50=1.16 μM; anticancer, from patent WO2018165385A1.</p>Formula:C20H15Cl2N7OColor and Shape:SolidMolecular weight:440.29IL-1β-IN-2
CAS:<p>IL-1β-IN-2, a cannabigerol derivative, serves as a potent inhibitor of IL-1β, exhibiting anti-inflammatory and pain-resolving properties [1].</p>Formula:C22H34O2Color and Shape:SolidMolecular weight:330.5CHS-111
CAS:<p>CHS-111 is a benzyl indazole that inhibits O2- generation, fMLP-induced PLD activity (IC50 3.9μM), and disrupts PLD1/Arf6 and RhoA interactions.</p>Formula:C21H18N2OPurity:98%Color and Shape:SolidMolecular weight:314.38AVE-9488
CAS:<p>AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.</p>Formula:C16H14FNOPurity:99.87%Color and Shape:SolidMolecular weight:255.29BAY32-5915
CAS:<p>BAY32-5915 is a selective inhibitor of IKKalpha.</p>Formula:C10H7NO3Purity:96.48% - 97%Color and Shape:Yellow Crystalline PowderMolecular weight:189.17UC-1V150
CAS:<p>UC-1V150: TLR7 agonist, triggers immune response, anti-tumor, precursor for ISAC synthesis.</p>Formula:C16H17N5O4Color and Shape:SolidMolecular weight:343.34YS-121
CAS:<p>YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).</p>Formula:C20H26ClN3O2SColor and Shape:SolidMolecular weight:407.96NBC 6
CAS:<p>NLRP3-IN-NBC6: potent NLRP3 inflammasome inhibitor, IC50 574 nM, Ca2+ independent, inhibits inflammasome in THP-1 cells/BMDMs.</p>Formula:C18H16BCl3N2O2Color and Shape:SolidMolecular weight:409.5STING ligand-1
CAS:<p>STING ligand-1 is a lead STING ligand(IC50 of 68 nM for HAQ STING).</p>Formula:C29H27ClFNO5Purity:98%Color and Shape:SolidMolecular weight:523.98FD-IN-1
CAS:<p>FD-IN-1: Factor D inhibitor, IC50=12 nM; blocks FXIa, Tryptase β2 (IC50s: 7.7 μM, 6.5 μM); key in innate immunity.</p>Formula:C23H23NO4Color and Shape:SolidMolecular weight:377.43Anti-inflammatory agent 8
CAS:<p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>Formula:C18H15N5OS2Color and Shape:SolidMolecular weight:381.47M62812 free base
CAS:<p>M62812 (free base), a Toll-like receptor 4 (TLR4) signal transduction inhibitor, suppresses activation of endothelial cells and leukocytes and prevents lethal</p>Formula:C13H11N3OSColor and Shape:SolidMolecular weight:257.31iNOS-IN-2
CAS:<p>iNOS-IN-2 (Compound 53) is a potent inducible nitric oxide synthase (iNOS) protein down-regulator.</p>Formula:C25H31NO7Color and Shape:SolidMolecular weight:457.52JAK2/STAT3-IN-1
CAS:<p>JAK2/STAT3-IN-1 is a GP130 inhibitor with anti-tumor effects and can be used to study inflammation, autoimmunity and cancer.</p>Formula:C34H35BrF3N5O2Purity:97.35%Color and Shape:SolidMolecular weight:682.57(R,1R)-Tenofovir amibufenamide
CAS:<p>(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used as a Tenofovir prodrug, which can be taken orally and has antiviral activity.</p>Formula:C22H31N6O5PPurity:98.79% - 99.02%Color and Shape:SolidMolecular weight:490.49SARS-CoV-2 nsp13-IN-1
CAS:<p>SARS-CoV-2 nsp13-IN-1 (C1) inhibits nsp13 ssDNA+ATPase (IC50: 6 μM), not ssDNA-ATPase; useful for COVID-19 research.</p>Formula:C27H20N4O2Purity:99.44%Color and Shape:SolidMolecular weight:432.47Prostaglandin G/H synthase 1 inhibitor
CAS:<p>Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.</p>Formula:C13H11ClN2OPurity:99.76%Color and Shape:SolidMolecular weight:246.697-NINA
CAS:<p>non-selective NOS inhibitor</p>Formula:C7H5N3NaO2Purity:98%Color and Shape:SolidMolecular weight:186.12R110
CAS:<p>R110 shows the potential for cancer research that is a potent, competitive MIF2 tautomerase inhibitor (IC 50 = 15 μM) [1].</p>Formula:C15H17ClN2OSColor and Shape:SolidMolecular weight:308.83TLR7 agonist 1
CAS:<p>TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).</p>Formula:C21H25N5OPurity:98%Color and Shape:SolidMolecular weight:363.46AZD8848
CAS:<p>AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.</p>Formula:C29H43N7O5Color and Shape:SolidMolecular weight:569.7
