Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(147 products)
- Cell wall(5 products)
- IL Receptor(113 products)
- IκB/IKK(61 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3035 products of "Immunology and Inflammation"
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GPCR Compound Library
<p>A unique collection of xnum GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target</p>Color and Shape:Odour SolidDeacetylgedunin
CAS:<p>Deacetylgedunin is a limonoid that is the 7-deacetyl derivative of gedunin. It has been isolated from Azadirachta indica.</p>Formula:C26H32O6Color and Shape:SolidMolecular weight:440.53HNW005
<p>HNW005 is a dual inhibitor targeting the NLRP3 inflammasome and urate transporter 1 (URAT1). It exhibits an inhibition constant (KD) of 204.6 nM and an IC50 of 1.7 μM for NLRP3 inflammasome activation, while demonstrating an IC50 of 6.4 μM for inhibiting uric acid transmembrane transport. At an administered dose of 2 mg/kg in vivo, HNW005 achieves a uric acid reduction rate of 64.8%, effectively providing anti-inflammatory, analgesic, and urate-lowering effects by inhibiting NLRP3 inflammasome activation and uric acid transport. HNW005 is applicable for research in gouty arthritis.</p>Color and Shape:Odour SolidFletikumab
CAS:<p>Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid</p>Purity:100% (SEC-HPLC) - > 95%Color and Shape:LiquidMolecular weight:146.48 kDaBasiliximab
CAS:<p>Basiliximab: chimeric IgG1 antibody inhibiting interleukin-2 receptor, used for kidney transplant immunosuppression.</p>Purity:SDS-PAGE:94.1%;SEC-HPLC:95.3%Color and Shape:LiquidMolecular weight:144.01 kDaβ-Interleukin II (44-56)
<p>β-Interleukin II is a peptide with the sequence NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH.</p>Formula:C68H113N19O19Purity:98%Color and Shape:SolidMolecular weight:1500.74(6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA
CAS:<p>(6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA ((6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-coenzyme A) acts as an NLRX1 modulator. This compound shows potential for research into immune and metabolism-related diseases.</p>Formula:C45H70N7O17P3SColor and Shape:SolidMolecular weight:1106.06Anti-PSMA Antibody
<p>Anti-PSMA Antibody is a humanized IgG1 monoclonal antibody targeting PSMA. It serves as the antibody component of the ADC molecule ARX517.</p>Color and Shape:Odour LiquidImmunology/Inflammation Compound Library
<p>A unique collection of xnum anti-inflammation compounds effective for high throughput screening and high content screening.</p>Color and Shape:Odour SolidMTvkPABC-P5
<p>MTvkPABC-P5d, functioning as a TLR7 agonist, serves as an immune stimulant and is utilized in the synthesis of immune-stimulating antibody conjugates (ISACs) [1</p>Formula:C52H73N11O14Color and Shape:SolidMolecular weight:1076.2Chemokine Inhibitor Library
<p>A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;</p>Color and Shape:Odour SolidHPPD-IN-1
<p>HPPD-IN-1 (compound II-3), a potent HPPD inhibitor, exhibits inhibitory activity against Arabidopsis thaliana HPPD (AtHPPD) with an IC50 of 0.248 μM, surpassing</p>Formula:C12H6F3NO4Color and Shape:SolidMolecular weight:285.182,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside
CAS:<p>2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside that is commonly found in the bulbs of</p>Formula:C20H27Cl3O12Color and Shape:SolidMolecular weight:565.78Modakafusp alfa
CAS:<p>Modakafusp alfa (TAK-573): Humanized anti-CD38 monoclonal antibody with IFNα2b for multiple myeloma research.</p>Color and Shape:LiquidComplement C1s-IN-1
CAS:<p>Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexes</p>Formula:C22H20F2N6OPurity:97.77%Color and Shape:SoildMolecular weight:422.43CTT2274
<p>CTT2274 is a prodrug of MMAE. It consists of a prostate-specific membrane antigen (PSMA) binding scaffold, a biphenyl motif, a pH-sensitive phosphoramidate linker, and an MMAE payload. CTT2274 selectively targets and binds to PSMA to deliver MMAE and has the capability to inhibit prostate cancer.</p>Formula:C119H159N17O33P2Color and Shape:SolidMolecular weight:2417.58Transcription Factor-Targeted Compound Library
<p>Well-chosen xnum compounds with unique structures targeting transcription factor;</p>Color and Shape:Odour SolidDihydromyristicin
CAS:<p>Dihydromyristicin, a plant flavonoid, curbs inflammation by inhibiting ROS and PI3K/Akt/NF-κB pathways.</p>Formula:C11H14O3Color and Shape:SolidMolecular weight:194.23Nonsteroidal Anti-Inflammatory Compound Library
<p>xnum non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.</p>Color and Shape:Odour SolidSTING agonist-13
CAS:<p>STING agonist-13 boosts cancer immunity by activating STING pathway, reducing tumors, and enhancing immune memory.</p>Formula:C45H53N15O7Color and Shape:SolidMolecular weight:916Biotin-labeled ODN 1018 sodium
<p>Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, serves as a tool for assessing cellular uptake and localization of CpG ODNs through</p>Color and Shape:Odour SolidPost-Translational Modification Compound Library
<p>Contains xnum active small molecules for research related to post-translational modifications (PTMs);</p>Color and Shape:Odour SolidFLY26
<p>FLY26 is a selective partial antagonist of GluN2B, with an IC50 value of 0.64 μM. FLY26 inhibits the GluN2B subunit of NMDA receptors, reducing calcium ion influx and reactive oxygen species (ROS) production. It also activates the BDNF/TrkB/CREB neuroprotective signaling pathway, mitigating excitotoxicity and mitochondrial dysfunction. FLY26 holds potential for treating neurological deficits caused by cerebral ischemia-reperfusion injury.</p>Formula:C22H23N5O3Color and Shape:SolidMolecular weight:405.18009Compstatin TFA
<p>Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).</p>Formula:C68H100F3N23O19S2Color and Shape:SolidMolecular weight:1664.79Inhibitor Library
<p>A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>Color and Shape:Odour SolidAnti-inflammatory agent 59
<p>Anti-inflammatory agent 58 is characterized by its ability to inhibit IL-1β with an IC50 value of 2.28 μM.</p>Color and Shape:Odour SolidNLRP3-IN-76
<p>NLRP3-IN-76 is an orally active NLRP3 inhibitor that suppresses the production of NO and reduces the mRNA levels of pro-inflammatory cytokines (iNOS, IL-6, IL-1β, and TNFα). It exerts anti-inflammatory effects by inhibiting the activation of the NLRP3 inflammasome and the NF-κB signaling pathway. Furthermore, NLRP3-IN-76 can ameliorate DSS-induced colitis and is applicable for studying inflammatory bowel disease (IBD).</p>Color and Shape:Odour SolidL-156,602
CAS:<p>L-156,602 has a wide range of applications in life science related research.</p>Formula:C38H64N8O13Color and Shape:SolidMolecular weight:840.973Ziltivekimab
CAS:<p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>Purity:95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)Color and Shape:SoildNT-0249
CAS:<p>NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.</p>Formula:C22H28N5NaO4SPurity:98.11%Color and Shape:SoildMolecular weight:481.54Fraxinellone analog 1
<p>Fraxinellone analog 1 (compound 2) is an effective and rapid activator of the Nrf2-mediated antioxidative defense system, providing protection against glutamate-mediated excitotoxicity. It induces the expression of antioxidative genes Gpx4, Sod1, and Nqo1. Additionally, Fraxinellone analog 1 exerts neuroprotective effects and modulates oxidative stress and inflammation, making it suitable for research on neurodegenerative diseases.</p>Color and Shape:Odour SolidHistone Modification Compound Library
<p>A unique collection of xnum histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Color and Shape:Odour SolidHistamine & Melatonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>Color and Shape:Odour SolidDihydrorhodamine 6G
CAS:<p>DHR 6G, nonfluorescent reduced Rhodamine 6G, permeates cells, indicating ROS by oxidizing to fluorescent form in mitochondria.</p>Formula:C28H32N2O3Color and Shape:SolidMolecular weight:444.57Diplacol
CAS:<p>Diplacol, a geranylated flavanone isolated from Paulownia trees (Paulownia coreana UYEKI), exhibits anti-inflammatory properties by inhibiting NO production in LPS-stimulated Raw264.7 cells with an IC50 value of 4.53 μM [1].</p>Formula:C25H28O7Color and Shape:SolidMolecular weight:440.49Ara-F-NAD+ sodium
<p>Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].</p>Formula:C21H25FN7NaO13P2Color and Shape:SolidMolecular weight:687.48-Nitroguanine
CAS:<p>8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant</p>Formula:C5H4N6O3Color and Shape:SolidMolecular weight:196.12IL-1β-IN-1
CAS:<p>IL-1β-IN-1, a cannabidiol derivative, acts as a potent inhibitor of IL-1β, exhibiting significant anti-inflammatory and pain relief properties [1].</p>Formula:C22H34O2Color and Shape:SolidMolecular weight:330.5Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH, a linker with TLR4-IN-C34, reduces inflammation in mice.</p>Formula:C78H125N7O36Color and Shape:SolidMolecular weight:1736.85BuChE-IN-20
<p>BuChE-IN-20 is a selective hBuChE inhibitor (IC50= 0.13 μM) with the ability to cross the blood-brain barrier (BBB). This compound, a derivative of L-Tryptophan, exhibits neuroprotective effects by inhibiting nitric oxide (NO) production and reducing reactive oxygen species (ROS) levels. It effectively suppresses the self-aggregation of amyloid-beta (Aβ) peptides and is applicable in Alzheimer's disease research.</p>Color and Shape:Odour SolidGuignardone L
CAS:<p>Guignardone L, a metabolite extracted from the endophytic fungus Guignardia mangiferae, possesses toll-like receptor 3 (TLR3) regulating activity [1].</p>Formula:C17H24O4Color and Shape:SolidMolecular weight:292.37Nasunin
CAS:<p>Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.</p>Formula:C42H47ClO23Color and Shape:SolidMolecular weight:955.26CLIP (86-100)
CAS:<p>Amino acids 86-100 of CLIP, replaced by DM to allow MHC class II to present foreign peptides, triggering immune response.</p>Formula:C72H128N20O19S3Purity:98%Color and Shape:SolidMolecular weight:1674.1MyD88-IN-1
CAS:<p>MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.</p>Formula:C23H24N6O7SPurity:>99.99%Color and Shape:SoildMolecular weight:528.54PS 1145 dihydrochloride
CAS:<p>IκB kinase (IKK) inhibitor</p>Formula:C17H13Cl3N4OPurity:98%Color and Shape:SolidMolecular weight:395.67Mik-β-1
<p>Mik-Beta-1 is a human IgG1-kappa monoclonal antibody targeting IL2RB. For isotype control, refer to Human IgG1 kappa, Isotype Control. Mik-Beta-1 is applicable in research related to the prevention of allograft rejection.</p>Color and Shape:Odour LiquidZuberitamab
CAS:<p>Zuberitamab (HS006) is a monoclonal antibody targeting CD20, utilized in cancer research, notably in diffuse large B-cell lymphoma [1].</p>Color and Shape:LiquidItolizumab
CAS:<p>Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6.</p>Purity:> 95%Color and Shape:LiquidMolecular weight:144.82 kDaExosome Compound Library
<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>Color and Shape:Odour SolidLemnalol
CAS:<p>Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.</p>Formula:C15H24OPurity:98%Color and Shape:SolidMolecular weight:220.35M-TriDAP TFA
<p>M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a bioactive peptide that functions as an agonist for NOD1/2.</p>Formula:C26H43N5O15·xC2HF3O2CNTO-6785
<p>CNTO-6785 is a humanized monoclonal antibody inhibitor that targets interleukin-17A (IL-17A). It holds potential for research in chronic obstructive pulmonary disease (COPD).</p>Color and Shape:Odour LiquidNurulimab
CAS:<p>Nurulimab (BCD-145) is an anti-CTLA-4 antibody with anti-cancer activity for the study of skin and musculoskeletal diseases.</p>Purity:95.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 95.5% (SDS-PAGE); 97.3% (SEC-HPLC)Color and Shape:LiquidBRCA2-IN-1
<p>BRCA2-IN-1 (Compound 3j) is a potential BRCA2 inhibitor with antiproliferative activity against the breast cancer MCF-7 cell line. This compound also demonstrates DPPH radical scavenging ability, with an IC50 value of 12.36 µM.</p>Color and Shape:Odour SolidMEDI-7836
<p>MEDI-7836 is a humanized monoclonal antibody inhibitor that targets the interleukin-13 (interleukin-13 receptor) receptor. It shows potential for research into diseases associated with inflammation.</p>Color and Shape:Odour LiquidBCL6 PROTAC 1
CAS:<p>BCL6 PROTAC 1: Selective BCL6 degrader, IC50 8.8 µM, used in DLBCL research.</p>Formula:C45H52ClN9O12Color and Shape:SolidMolecular weight:946.4Pterisolic acid B
<p>Pterisolic acid B is a useful organic compound for research related to life sciences and the catalog number is T125924.</p>Formula:C20H26O4Color and Shape:SolidMolecular weight:330.424Xanthine oxidase-IN-12
<p>Xanthine oxidase-IN-12 (Compound 11), an inhibitor of xanthine oxidase (XO), possesses an IC50 value of 91 nM and exhibits antioxidant properties, additionally</p>Purity:98%Color and Shape:Odour SolidMAPK Inhibitor Library
<p>A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;</p>Color and Shape:Odour SolidGuretolimod hydrochloride
<p>Guretolimod hydrochloride acts as an agonist for Toll-like receptor 7 (TLR7) [1].</p>Formula:C24H35ClF3N5O4Color and Shape:SolidMolecular weight:550.01COX-2-IN-48
<p>COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.</p>Color and Shape:Odour SolidBMS-986251
CAS:<p>BMS-986251: Oral RORγt inverse agonist, EC50 12 nM; inhibits IL-17 (EC50 24 nM); effective in mouse psoriasis models.</p>Formula:C30H29F8NO5SColor and Shape:SolidMolecular weight:667.61Cartap hydrochloride
CAS:<p>Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.</p>Formula:C18H33Cl2CuN3O3Color and Shape:Colorless Crystalline Slightly Hygroscopic Solid CoaMolecular weight:473.93Mepolizumab
CAS:<p>Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5.</p>Purity:98% - 98%Color and Shape:LiquidBiotinoyl tripeptide-1
CAS:<p>Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.</p>Formula:C24H38N8O6SPurity:98%Color and Shape:SolidMolecular weight:566.67Aspulvinone O
CAS:<p>Aspulvinone O, from P. variotti, is an antioxidant with anticancer properties, inhibits GOT1, and reduces SW1990 pancreatic tumor growth in mice.</p>Formula:C27H28O6Color and Shape:SolidMolecular weight:448.515Bengamide B
CAS:<p>Potent NF-κB inhibitor, IC50 at 85 nM. Reduces IκBα phosphorylation, NO, TNF-α, IL-6, MCP. Inhibits HeLa, HCT116 cell growth. Anti-inflammatory, antitumor.</p>Formula:C32H58N2O8Color and Shape:SolidMolecular weight:598.81CD73-IN-16
<p>CD73-IN-16 (compound 18) acts as an inhibitor of hCD73, exhibiting an IC50 value of 0.28 μM.</p>Color and Shape:Odour SolidSacituzumab tirumotecan
CAS:<p>Sacituzumab tirumotecan (SKB264) is an antibody-drug conjugate (ADC) targeting TROP2 (trophoblast cell surface antigen 2), capable of releasing the active payload KL610023 within TROP2-positive tumour cells. an effective topoisomerase I inhibitor that induces DNA damage and leads to cell cycle arrest and apoptosis, for use in non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC).</p>Purity:99%Color and Shape:LiquidPIC1 PA TFA
<p>PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.</p>Formula:C71H123N19O21S2·xC2HF3O2Color and Shape:SolidS7
CAS:<p>S7, an IL-6 receptor antagonist, prevents the interaction between IL-6 and IL-6R, thereby inhibiting angiogenesis and tumor growth [1].</p>Formula:C37H70N10O10Color and Shape:SolidMolecular weight:815.01FITC-labeled ODN 1018 sodium
<p>FITC-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, facilitates the assessment of CpG ODN cellular uptake and localization through confocal</p>Color and Shape:SolidMolecular weight:8171Prostaglandin D synthase
CAS:<p>Prostaglandin D synthase is a biomarker for meningioma cells and coronary artery disease. Lipocalin-type prostaglandin D synthase (L-PGDS) is found in human coronary atherosclerotic plaques and can be detected in human serum.</p>Color and Shape:SolidHuangjiangsu A
CAS:<p>Huangjiangsu A, from D. villosa, may protect the liver from H2O2 damage and reduce ROS, showing therapeutic promise.</p>Formula:C51H82O22Purity:98%Color and Shape:SolidMolecular weight:1047.18KTX-951
CAS:<p>KTX-951, a PROTAC, degrades IRAK4 (DC50=18 nM), 22% oral bioavailability in rats, shows promise as anticancer agent.</p>Formula:C46H52F2N8O6Color and Shape:SolidMolecular weight:850.95Ubletamig
CAS:<p>Ubletamig is a humanized IgG4κ monoclonal antibody that targets MUC16.</p>Color and Shape:LiquidSDH-IN-23
<p>SDH-IN-23 (Compound B21) is an SDH inhibitor with exceptional nematicidal activity. It can suppress nematode feeding, reproduction, and embryonic development while also inducing lethal effects through mechanisms such as oxidative stress, intestinal damage, and SDH inhibition.</p>Formula:C19H11ClF6N2O2Color and Shape:SolidMolecular weight:448.75TLR8 agonist 7
CAS:<p>TLR8 agonist7 is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of less than 250 nM. It remains stable in human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist7 demonstrates antitumor activity, achieving a tumor growth inhibition (TGI) rate of 98%.</p>Formula:C54H63N9O16Color and Shape:SolidMolecular weight:1094.13Nogapendekin alfa inbakicept
CAS:<p>Nogapendekin alfa inbakicept is an IL-15 superagonist that enhances anti-tumor immune responses by activating NK cells and T cells. It is being studied for use in non-muscle invasive bladder cancer (NMIBC).</p>Color and Shape:SolidPROTAC IRAK4 degrader-3
CAS:<p>PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau.</p>Formula:C57H68FN11O8SColor and Shape:SolidMolecular weight:1086.3NOX4-IN-1
<p>NOX4-IN-1 (Compound 14m) is an inhibitor of NADPH oxidase 4 (NOX4) that reduces the production of reactive oxygen species (ROS). It also inhibits the TGF-β1/Smad signaling pathway, leading to decreased expression of fibrosis-related proteins. Additionally, NOX4-IN-1 impedes the migration of NRK-49F cells.</p>Formula:C26H16ClN3O3Color and Shape:SolidMolecular weight:453.877MAO-B-IN-39
<p>MAO-B-IN-39 (compound11) is a potent inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 3.61 μM. It demonstrates strong NRF2 induction capabilities and exhibits significant anti-inflammatory and neuroprotective effects in oxidative stress-related in vitro models. Additionally, MAO-B-IN-39 shows high liver microsomal stability and favorable pharmacokinetic properties in mice, making it a valuable compound for Parkinson's disease research.</p>Formula:C17H13FN2OColor and Shape:SolidMolecular weight:280.3Endoplasmic Reticulum Stress Compound Library
<p>A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);</p>Color and Shape:Odour SolidVarokibart
CAS:<p>Varokibart (TEV-53275) is a human IgG4λ antibody that targets interleukin-5 (IL-5) [1].</p>Color and Shape:LiquidM133 peptide
<p>The M133 peptide is a coronavirus-specific CD4 T cell epitope. In mice infected with the neurotropic coronavirus (strain JHM of mouse hepatitis virus), the M133 peptide demonstrates immunodominance. It activates CD4 T cells by forming an MHC/peptide complex through binding with MHC II molecules, which is recognized by specific TCRs.</p>Formula:C84H130N20O25Molecular weight:1818.9516Biotin-labeled ODN 2088 sodium
<p>Biotin-labeled ODN 2088 (sodium) acts as a potent inhibitor of TLR3, TLR7, and TLR9.</p>Color and Shape:Odour SolidArginase inhibitor 9
<p>Arginase inhibitor9 (Compound 12a) is a type of arginase enzyme inhibitor with IC50 values of 9 μM for bovine and 55 μM for human arginase I. It also exhibits antioxidant activity by scavenging free radicals. Moreover, Arginase inhibitor9 effectively regulates collagen and procollagen levels, thereby exerting an anti-fibrotic effect.</p>Formula:C13H11NO4SColor and Shape:SolidMolecular weight:277.3Nuclear Receptor Compound Library
<p>A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;</p>Color and Shape:Odour SolidPhotosensitizer-4
<p>Compound PS-I (Photosensitizer-4) is an effective photosensitizer that can efficiently kill cancer cells and inhibit tumor growth under light exposure.</p>Color and Shape:Odour SolidSacituzumab MMAE
<p>Sacituzumab-MMAE (CHB295) Anti-TROP2 Reference Antibody is produced in CHO cells and consists of a huIgG1 heavy chain and a hukappa light chain. This compound has a predicted molecular weight (MW) of 146.06 kDa.</p>Color and Shape:LiquidMolecular weight:150 kDaEPI-589
CAS:<p>EPI-589, a quinone oxidoreductase inhibitor, may treat ALS; it's safe and tolerable.</p>Formula:C14H19NO4Purity:98%Color and Shape:SolidMolecular weight:265.31(±)11(12)-EET
CAS:<p>(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.4719-epi-Scholaricine
CAS:<p>19-epi-Scholaricine: indole alkaloid, taken orally, reduces collagen fibrosis, boosts SOD.</p>Formula:C20H24N2O4Color and Shape:SolidMolecular weight:356.42PNT2001
CAS:<p>PNT2001 (LY4181530) is an effective prostate-specific membrane antigen (PSMA) ligand with an IC50 of 3.1 nM. It enhances cellular internalization and, when labeled with 177Lu and 225Ac, is applicable for prostate cancer research.</p>Formula:C85H107N15O32Color and Shape:SolidMolecular weight:1850.84Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Color and Shape:Odour SolidRomilkimab
CAS:<p>Romilkimab (SAR156597) is a chimeric humanized immunoglobulin (Ig) antibody designed to specifically target interleukins 4 and 13 (IL-4 and IL-13) [1].</p>Color and Shape:LiquidAntiparasitic agent-26
<p>Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).</p>Color and Shape:Odour SolidR-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Formula:C22H19N3O2S2Color and Shape:SolidMolecular weight:421.54Antibacterial agent 119
<p>Antibacterialagent 119 (Compound 21 g) is a potential antibacterial agent effective against methicillin-resistant Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of less than 1 μg/mL against tested strains. It induces reactive oxygen species (ROS) generation and disrupts bacterial cell membranes, causing their rupture. Antibacterialagent 119 exhibits strong antimicrobial activity, low cytotoxicity, rapid bactericidal action, and favorable in vivo antibacterial efficacy.</p>Formula:C42H54BrClN2O4Color and Shape:SolidMolecular weight:766.246TGF-β/Smad Compound Library
<p>A unique collection of xnum TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;</p>Color and Shape:Odour SolidGinger extract
CAS:<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Color and Shape:SolidCNTO4088
<p>CNTO4088 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It holds potential for research in autoimmune diseases such as psoriasis and rheumatoid arthritis.</p>Color and Shape:Odour LiquidBivalirudin TFA
CAS:<p>Bivalirudin TFA, a 20-residue synthetic peptide, reversibly inhibits thrombin, affecting platelet aggregation and thrombin generation.</p>Formula:C98H138N24O33·C2HF3O2Color and Shape:SolidMolecular weight:2294.34Ieramilimab
<p>Ieramilimab (LAG525) is a humanized antibody targeting LAG-3 with potential anticancer activity for the study of malignant tumors.</p>Purity:96.4% (SDS-PAGE); 97.8% (SEC-HPLC) - 96.4% (SDS-PAGE); 97.8% (SEC-HPLC)Color and Shape:Odour LiquidNLRP3-IN-48
<p>NLRP3-IN-48 is an inhibitor of NLRP3. It suppresses the activation of the NLRP3 inflammasome by targeting the NLRP3 protein, thereby interfering with the assembly of the NLRP3 inflammasome. Additionally, NLRP3-IN-48 exhibits anti-inflammatory activity in a DSS-induced acute colitis model in mice.</p>Color and Shape:Odour SolidMosnodenvir
CAS:<p>Mosnodenvir is a pan-DENV inhibitor effective against all four serotypes of dengue viruses, with the advantage of being highly potent and orally bioavailable, and blocks viral replication by inhibiting the formation of the complex between NS3 and NS4B.</p>Formula:C26H22ClF3N2O6SPurity:99.72%Color and Shape:SoildMolecular weight:582.98BMS-986179
<p>BMS-986179 is a human monoclonal antibody targeting NT5E/CD73. It inhibits CD73 enzymatic activity both in tumor vasculature and tumor cells. BMS-986179 is applicable for research in advanced solid tumors.</p>Color and Shape:Odour LiquidNLRP3-IN-14
CAS:<p>NLRP3-IN-14, potent selective NLRP3 inhibitor, KD 5.87μM; IC50 0.131μM for IL-1β; for inflammation research.</p>Formula:C27H28N2O4Color and Shape:SolidMolecular weight:444.52PMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Formula:C47H63F3N10O8Color and Shape:SolidMolecular weight:953.06Moxilubant HCl
CAS:<p>Moxilubant HCl: small molecule LTB4R antagonist for immune, skin, musculoskeletal disorders, and research in psoriasis, arthritis.</p>Formula:C26H38ClN3O4Purity:99.94%Color and Shape:SoildMolecular weight:492.05C6 L-threo Ceramide (d18:1/6:0)
CAS:<p>C6 L-threo Ceramide: bioactive sphingolipid, cytotoxic to U937 cells (IC50=18μM), non-metabolic, boosts IL-4 in T cells at 10μM.</p>Formula:C24H47NO3Color and Shape:SolidMolecular weight:397.63ZL-1102
<p>ZL-1102 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). SCH-900117 is being investigated for its potential use in the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis.</p>Color and Shape:Odour LiquidRucosopasem manganese
CAS:<p>Rucosopasem manganese (GC4711), a selective SOD mimetic, converts superoxide to peroxide for cancer research.</p>Formula:C27H45MnN5O4Color and Shape:SolidMolecular weight:558.626Phthalazine
CAS:<p>Compound PDK0135, with CAS No. 253-52-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0135 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C8H6N2Color and Shape:Yellow SolidMolecular weight:130.14Butan-1-amine hydrochloride
CAS:<p>1-Butylamine hydrochloride,butylamine, a potential agonist of Nrf2/ARE (Nuclear Factor Erythroid 2 Associated Factor 2/Antioxidant Response Element).</p>Formula:C4H12ClNColor and Shape:SolidMolecular weight:109.6AMY-101
CAS:<p>AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.</p>Formula:C83H117N23O18S2Purity:98%Color and Shape:SolidMolecular weight:1789.111-Ethoxycarbonyl-β-carboline
CAS:<p>1-Ethoxycarbonyl-β-carboline is a natural product for research related to life sciences. The catalog number is TN7072 and the CAS number is 72755-19-2.</p>Formula:C28H23N4O4Color and Shape:SolidMolecular weight:479.516Tetrachlorohydroquinone
CAS:<p>TCHQ, a pentachlorophenol metabolite, toxic to trout liver cells, increases ROS, disrupts mitochondria, and causes necrosis in splenocytes. EC50: 1.55 μM.</p>Formula:C6H2Cl4O2Color and Shape:SolidMolecular weight:247.89iE-DAP dihydrochloride
<p>iE-DAP dihydrochloride is a Nod1 agonist that activates the NF-κB pathway through recognition by Nod1, leading to an inflammatory cytokine response. This compound is useful for studying maternal-fetal inflammation and preterm birth.</p>Formula:C12H23Cl2N3O7Color and Shape:SolidMolecular weight:391.09131Allyl methyl trisulfide
CAS:<p>Allyl methyl trisulfide: a garlic oil compound with antibacterial, antioxidant, and antitumor properties.</p>Formula:C4H8S3Color and Shape:SolidMolecular weight:152.3CAY10614
CAS:<p>CAY10614 is a TLR4 antagonist.</p>Formula:C42H78INO2Color and Shape:SolidMolecular weight:755.995Sirtuin modulator 2
CAS:<p>Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.</p>Formula:C19H15N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:349.41STING modulator-5
CAS:<p>STING modulator-5: pIC50 9.5, antagonizes PBMC (pIC50 8.1), THP-1 cell antagonist, for immunology research.</p>Formula:C43H45F4N11O5Color and Shape:SolidMolecular weight:871.88Salicortin
CAS:<p>Salicortin, a phenolic glycoside from Populus and Salix, has anti-adipogenic, anti-amnesic, and immune effects.</p>Formula:C20H24O10Purity:98%Color and Shape:SolidMolecular weight:424.40Polyinosinic acid
CAS:<p>Polyinosinic acid: single-strand, TLR3 agonist, boosts immune response, has immune regulation uses.</p>Formula:(C10H13N4O8P)xColor and Shape:SolidSTING agonist-17
CAS:<p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>Formula:C43H53N13O8Color and Shape:SolidMolecular weight:879.96QX-005N
<p>QX 005N is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. It is applicable in research related to asthma.</p>Color and Shape:Odour LiquidKYN-101
CAS:<p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>Formula:C22H19FN6Purity:98.35%Color and Shape:SolidMolecular weight:386.43Isoxaben
CAS:<p>Isoxaben (EL 107) is a specific inhibitor of cell wall biosynthesis, often used as a herbicide, that inhibits the incorporation of radiolabeled glucose into</p>Formula:C18H24N2O4Purity:98.84%Color and Shape:SolidMolecular weight:332.39ATWLPPR Peptide TFA
<p>ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.</p>Formula:C42H62F3N11O11Purity:98%Color and Shape:SolidMolecular weight:954cGAMP disodium
CAS:<p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>Formula:C20H24N10O13P2·2NaColor and Shape:SoildMolecular weight:720.39FM101
<p>FM101 is a humanized monoclonal anti-IL6 antibody, suitable for use in asthma-related research.</p>Color and Shape:Odour LiquidNLRP3-IN-49
<p>NLRP3-IN-49 (compound Z48) is a potent and specific inhibitor of NLRP3, displaying IC50 values of 0.26 μM in THP-1 cells and 0.21 μM in mouse bone marrow-derived macrophages. It directly binds to the NLRP3 protein with a dissociation constant (Kd) of 1.05 μM, effectively preventing the assembly and activation of the NLRP3 inflammasome, thereby exhibiting anti-inflammatory properties. NLRP3-IN-49 is utilized in the research of inflammatory bowel disease.</p>Color and Shape:Odour SolidPhytoene desaturase-IN-1
CAS:<p>Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.</p>Formula:C18H13ClF3N3O2SColor and Shape:SolidMolecular weight:427.83Valeriandoid F
CAS:<p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>Formula:C23H34O9Color and Shape:SolidMolecular weight:454.516Timosaponin E2
CAS:<p>Timosaponin E2 is an anti-inflammatory agent that inhibits active oxygen production [1].</p>Formula:C46H78O20Color and Shape:SolidMolecular weight:951.1Mesalamine impurity P
CAS:<p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>Formula:C13H11NO6SColor and Shape:SolidMolecular weight:309.30TLR4 agonist-1 TEA
<p>TLR4 agonist-1 (TEA, compound 17a) is a potent activator of Toll-like Receptor 4 (TLR4) and prompts the production of MIP-1β in RAW 264.7 and MM6 cells [1].</p>Color and Shape:Odour SolidMCI
<p>MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation</p>Formula:C45H52ClN7O13Purity:98%Color and Shape:SolidMolecular weight:934.39CAY10657
CAS:<p>CAY10657 has a wide range of applications in life science related research.</p>Formula:C17H20N4O3SColor and Shape:SolidMolecular weight:360.43GSK1795091
CAS:<p>GSK1795091, a synthetic TLR4 agonist, boosts immunity and shows antitumor effects, enhancing flu vaccine response.</p>Formula:C81H157N2O16PColor and Shape:SolidMolecular weight:1446.119COX-2/15-LOX-IN-2
<p>COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.</p>Formula:C27H26N6OS2Purity:98%Color and Shape:SolidMolecular weight:514.66Feeblin
CAS:<p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>Formula:C27H33N3O2Purity:99.58% - 99.88%Color and Shape:SoildMolecular weight:431.57LL-37 GKE acetate
<p>LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.</p>Formula:C121H206N38O30Purity:99.88%Color and Shape:SolidMolecular weight:2673.17Gliotoxin
CAS:<p>Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.</p>Formula:C13H14N2O4S2Purity:98%Color and Shape:SolidMolecular weight:326.39Gp100 (25-33), human
CAS:<p>Gp100 (25-33), human: 9-AA melanoma antigen fragment, H-2Db restricted, T-cell recognized, targets B16 melanoma.</p>Formula:C52H82N16O14Purity:98%Color and Shape:SolidMolecular weight:1155.31PROTAC STING Degrader-1
CAS:<p>PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader exhibiting a DC50 of 3.2 μM and demonstrates anti-inflammatory activity [1].</p>Formula:C34H33N7O10Color and Shape:SolidMolecular weight:699.67NF-κΒ activator 1
CAS:<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Formula:C16H11FN2O2SPurity:99.58%Color and Shape:SolidMolecular weight:314.33Balekafusp alfa
CAS:<p>Balekafusp alfa is a human IgG1κ antibody targeting IL-2, known for its antitumor properties.</p>Color and Shape:Liquid3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide
CAS:<p>3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).</p>Formula:C28H24ClN3O6Purity:99.9%Color and Shape:SolidMolecular weight:533.961-Hydroxy-ibuprofen
CAS:<p>1-Hydroxy Ibuprofen, a metabolite in P. australis, targets COX-1/COX-2 with IC50s: 13 μM/370 μM.</p>Formula:C13H18O3Color and Shape:SolidMolecular weight:222.2802Anti-IL11RA Antibody (X209)
<p>Anti-IL11RA Antibody (X209) is a human-derived IgG4, κ type antibody inhibitor targeting human IL-11RA.</p>Color and Shape:Odour LiquidMifamurtide sodium
CAS:<p>Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.</p>Formula:C59H108N6NaO19PPurity:98%Color and Shape:SolidMolecular weight:1259.48NF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Formula:C62H50N4O4SColor and Shape:SolidMolecular weight:947.15[12]-Dehydrogingerdione
CAS:<p>[12]-Dehydrogingerdione is a natural product found in ginger that has anti-neuroinflammatory activity.Cost-effective and quality-assured.</p>Formula:C23H34O4Purity:98%Color and Shape:SolidMolecular weight:374.51Aminopicoline
CAS:<p>Compound Fr16695, with CAS No. 695-34-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16695 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C6H8N2Color and Shape:White To Pale Yellow Solid FlakesMolecular weight:108.14Cyclic-di-GMP disodium
CAS:<p>Cyclic-di-GMP disodium (5GP-5GP disodium) is a STING agonist and a second messenger in bacteria.Cost-effective and quality-assured.</p>Formula:C20H22N10Na2O14P2Purity:98.98% - 99.93%Color and Shape:SolidMolecular weight:734.38E7766 disodium
CAS:<p>E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.</p>Formula:C24H26F2N10Na2O8P2S2Color and Shape:SolidMolecular weight:792.58HNGF6A
CAS:<p>increases glucose stimulated insulin secretion and glucose metabolism</p>Formula:C112H198N34O31S2Purity:98%Color and Shape:SolidMolecular weight:2581.11STING-IN-13
<p>STING-IN-13 is a selective STING inhibitor that effectively suppresses downstream signaling of the STING pathway and STING-mediated inflammation. It exhibits low toxicity and is suitable for research related to STING-associated inflammatory and autoimmune diseases.</p>Color and Shape:Odour SolidPSMA-IN-3
<p>PSMA-IN-3 (compound 17) is a novel, high-affinity inhibitor of Prostate-Specific Membrane Antigen (PSMA) with an inhibitory concentration (IC50) of 13 nM,</p>Formula:C43H50FN7O15Color and Shape:SolidMolecular weight:923.89CFT7455
CAS:<p>CFT7455: orally active anti-cancer drug, targets cereblon E3 ligase (Kd 0.9 nM), degrades IKZF1/Ikaros, IKZF3/Aiolos.</p>Formula:C28H27N3O4Purity:97.93%Color and Shape:SolidMolecular weight:469.53JH-FK-08
<p>JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.</p>Formula:C45H73N3O13Color and Shape:SolidMolecular weight:864.073Obinutuzumab
CAS:<p>Obinutuzumab (Obinutuzumab/afutuzumab) GA101) is a glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.</p>Purity:98.00% - 98.9% (SDS-PAGE); 99.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.6 kDaNLRP3-IN-74
<p>NLRP3-IN-74 (Compound 11) is an orally active NLRP3 inhibitor with an IC50 of 2.7 μM. It significantly reduces IL-1β release by approximately 90% without affecting TNFα release. NLRP3-IN-74 is applicable in research on diseases such as atherosclerosis and Parkinson's disease.</p>Color and Shape:Odour SolidEftilagimod alfa
CAS:<p>Eftilagimod alfa (IMP321), a recombinant LAG-3Ig fusion protein, binds to MHC class II and mediates the activation of antigen-presenting cells (APCs), which in</p>Color and Shape:LiquidLY2409881
CAS:<p>LY2409881 is a selective IκB kinase β ( IKK2 ) inhibitor with an IC 50 of 30 nM.</p>Formula:C24H29ClN6OSColor and Shape:SolidMolecular weight:485.05TLR8 agonist 8
CAS:<p>TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.</p>Formula:C53H63N11O10Color and Shape:SolidMolecular weight:1014.14HPK1-IN-58
<p>HPK1-IN-58 is an inhibitor of HPK1 (IC50: 2.6 nM) and SLP76 (IC50: 20 nM). It enhances IL-2 secretion, thereby reversing PGE2-induced immunosuppression. HPK1-IN-58 is applicable for research in antitumor immunity.</p>Formula:C26H30N8OColor and Shape:SolidMolecular weight:470.25426Cryogenine
CAS:<p>Cryogenine, from H. salicifolia, is an anti-inflammatory alkaloid, blocks prostaglandin synthetase, and alleviates rat arthritis.</p>Formula:C26H29NO5Color and Shape:SolidMolecular weight:435.52Antidesmone
CAS:<p>Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.</p>Formula:C19H29NO3Purity:98%Color and Shape:SolidMolecular weight:319.44Sericin
<p>Sericin is a globular protein isolated from silkworm cocoons. It has cognitive enhancement and pain-relieving properties. Additionally, Sericin serves as a cryoprotectant, potentially replacing fetal bovine serum or dimethyl sulfoxide (DMSO). It helps reduce oxidative stress and reactive oxygen species (ROS). Sericin aids in wound repair by promoting collagen production and exhibits activities such as antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, moisturizing, wound healing promotion, antibacterial, and antitumor effects.</p>Color and Shape:Odour SolidFGT-4
<p>FGT-4 is a chimeric molecule targeting folate receptor β (FR-β) and functions as a TLR7 agonist. It enhances the secretion of iNOS and the pro-inflammatory cytokine IL-6 associated with M1 macrophages and promotes the proliferation of cytotoxic CD8+ T cells. FGT-4 demonstrates antitumor activity in the 4T1 breast cancer mouse model and is applicable for cancer immunotherapy research.</p>Formula:C50H57N11O9S2Color and Shape:SolidMolecular weight:1019.37821c-di-AMP disodium
CAS:<p>c-di-AMP sodium: STING agonist, activates TBK3-IRF3 pathway, boosts type I IFN/TNF, regulates bacterial growth/virulence, and stimulates immune responses.</p>Formula:C20H22N10Na2O12P2Color and Shape:SolidMolecular weight:702.38TLR7 agonist 17
CAS:<p>TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].</p>Formula:C25H37N7O3Color and Shape:SolidMolecular weight:483.61ODN D-SL03
CAS:<p>ODN D-SL03, a C class CpG oligonucleotide, stimulates PBMCs, activating B cells, NK cells & monocytes, and can inhibit tumor growth.</p>Color and Shape:SolidMolecular weight:9345Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Formula:C20H28O6Color and Shape:SolidMolecular weight:364.437-O-Methylaloeasinol
CAS:<p>7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.</p>Formula:C20H26O9Color and Shape:SolidMolecular weight:410.419His-Pro
CAS:<p>His-Pro is a dipeptide consisting of histidyl and proline.</p>Formula:C11H16N4O3Purity:98%Color and Shape:SolidMolecular weight:252.27Ketoprofen lysine salt
CAS:<p>Ketoprofen lysine salt is a lysine salt of ketoprofen, a Non-Steroidal Anti-Inflammatory Drug</p>Formula:C22H28N2O5Color and Shape:SolidMolecular weight:400.483′-Hydroxy-4′-O-methylglabridin
CAS:<p>3′-Hydroxy-4′-O-methylglabridin effectively prevents NADH-dependent peroxidation, exhibiting potent antioxidant properties [1].</p>Formula:C21H22O5Color and Shape:SolidMolecular weight:354.4Helenalin
CAS:<p>Helenalin: anti-inflammatory sesquiterpene, inhibits NF-κB by alkylating p65 cysteine groups, blocks DNA binding.</p>Formula:C15H18O4Purity:98%Color and Shape:SolidMolecular weight:262.37-Deoxy-trans-dihydronarciclasine
CAS:<p>7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-</p>Formula:C14H15NO6Color and Shape:SolidMolecular weight:293.27Glutathione ethyl ester acetate
<p>Glutathione ethyl ester acetate is an antioxidant and cell-permeable Glutathione (GSH) donor that restore oxidative stress and TGase up-regulation.</p>Formula:C14H25N3O8SPurity:97.49%Color and Shape:SolidMolecular weight:395.43Romurtide
CAS:<p>Romurtide is a synthetic muramyl dipeptide analog and can be used for the prophylaxis of leukocytopenia during radiation therapy.</p>Formula:C43H78N6O13Purity:98%Color and Shape:SolidMolecular weight:887.126Bavunalimab
CAS:<p>Bavunalimab: bispecific anti-CTLA-4/LAG-3 antibody, T-cell activator in NSG mice, for cancer research.</p>Color and Shape:LiquidFM-303
<p>FM-303 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It shows promise for research in immune system and digestive system diseases.</p>Color and Shape:Odour LiquidG3-C12
CAS:<p>G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.</p>Formula:C74H115N23O23S2Purity:98%Color and Shape:SolidMolecular weight:1758.99Prezalumab
CAS:<p>Prezalumab (AMG 557) is a human IgG2 monoclonal antibody against ICOSL and BAFF.</p>Purity:> 95%Color and Shape:LiquidMolecular weight:145.42 kDaSTING agonist-8 dihydrochloride
<p>STING Agonist-8 Dihydrochloride (Compound 5-AB) is a highly effective STING agonist, exhibiting an EC50 value of 27 nM in THP1-Dual KI-hSTING-R232 cells.</p>Formula:C41H48Cl2N14O4Color and Shape:SolidMolecular weight:871.82N-decanoyl-L-Homoserine lactone
CAS:<p>C10-HSL, an AHL from Pseudomonas cremoris ND07, stunts Arabidopsis roots by raising Ca2+, ROS, MPK6 activity, and NO levels.</p>Formula:C14H25NO3Purity:99.81%Color and Shape:SolidMolecular weight:255.35Ladanetin-6-O-β-D-glucopyranoside
CAS:<p>Ladanetin-6-O-β-D-glucopyranoside, an active flavonoid, exhibits antioxidative effects and has potential for research into cardioprotective effects [1].</p>Formula:C22H22O11Color and Shape:SolidMolecular weight:462.4BRD5075
<p>BRD5075 is an effective activator of GPR65, stimulating the production of cAMP in a GPR65-dependent manner. Additionally, it reduces the gene expression of IL-1, IL-2, TNF, and chemokines. BRD5075 holds potential for researching multiple sclerosis and inflammatory bowel disease (IBD).</p>Color and Shape:Odour SolidCRX 527
CAS:<p>CRX 527 is a TLR4 ligand and serves as an adjuvant for peptide cancer vaccines, enhancing anti-tumor immune responses. CRX 527 also induces hematopoietic stem cell (HSC) differentiation, increasing the proportion and number of LSK cells, and promotes their differentiation into macrophages. This activation bolsters immune defense and protects intestinal epithelium from radiation damage.</p>Formula:C81H151N2O19PColor and Shape:SolidMolecular weight:1488.04SIN 14
<p>SIN 14 is an HO-1 activator that targets and activates HO-1 through an allosteric mechanism. Additionally, SIN 14 can induce the polarization of macrophages from the M1 phenotype to the M2 phenotype.</p>Formula:C20H22ClNO4Color and Shape:SolidMolecular weight:375.12374Pam2CSK4
CAS:<p>TLR2/6 agonist; boosts TNF-α in human cells & mouse B cell growth/activation.</p>Formula:C65H126N10O12SPurity:98%Color and Shape:SolidMolecular weight:1271.83MethADP sodium salt
CAS:<p>MethADP is a specific CD73 inhibitor.</p>Formula:C11H17N5NaO9P2Purity:98%Color and Shape:SolidMolecular weight:448.22KD014
<p>KD014 (DX-2400) is a human monoclonal antibody (mAb) that targets MMP14, with a Ki of 0.9 nM. It inhibits TGFβ and SMAD2/3 signaling, increases macrophage count and iNOS expression, and shifts macrophage phenotype towards an antitumor M1-like type. KD014 exhibits antitumor activity in three tumor models (MDA-MB-231, MDA-MB-435, and PC3) and is applicable in breast cancer research.</p>Color and Shape:Odour LiquidReltecimod
CAS:<p>Reltecimod, a CD28 antigen inhibitor, is used potentially for the treatment of necrotizing soft tissue infection.</p>Formula:C46H72N10O15SPurity:98%Color and Shape:SolidMolecular weight:1037.19cGAMP diammonium
<p>cGAMP is a second messenger that triggers interferon production via STING activation upon detecting cytosolic DNA.</p>Formula:C20H30N12O13P2Color and Shape:SolidMolecular weight:708.47
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