Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(147 products)
- Cell wall(5 products)
- IL Receptor(113 products)
- IκB/IKK(61 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3035 products of "Immunology and Inflammation"
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CDD-3290
<p>CDD-3290 (Compound 20) is an inhibitor of prostate-specific antigen (PSA) with a Ki value of 216 nM. This compound also exhibits inhibitory effects on α-chymotrypsin and elastase.</p>Color and Shape:Odour SolidZ-VRPR-FMK TFA
<p>Z-VRPR-FMK (TFA), a tetrapeptide, irreversibly inhibits MALT1, protecting against influenza A.</p>Formula:C33H50F4N10O8Color and Shape:SolidMolecular weight:790.81TLR7/8 agonist 4 TFA
CAS:<p>TLR7/8 agonist 4 TFA (compound 41) is a highly potent TLR7/8 agonist that exhibits significant anti-cancer activity.</p>Formula:C20H25F3N6O2Color and Shape:SolidMolecular weight:438.45RDR 02308
CAS:<p>RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase [1] .</p>Formula:C19H15N3O3Color and Shape:SolidMolecular weight:333.34Dectrekumab
CAS:<p>Dectrekumab (QAX576) is a humanized monoclonal antibody targeting IL-13.</p>Purity:96.5% (SDS-PAGE); 97.1% (SEC-HPLC) - 96.5% (SDS-PAGE); 97.1% (SEC-HPLC)Color and Shape:LiquidTP508
CAS:<p>TP508 (Chrysalin), a 23-amino-acid peptide from human prothrombin, aids in tissue repair, targeting thrombin receptors.</p>Formula:C97H146N28O36SPurity:98%Color and Shape:SolidMolecular weight:2312.44IKKγ NBD Inhibitory Peptide
CAS:<p>A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF</p>Formula:C170H259N49O42S1Purity:98%Color and Shape:SolidMolecular weight:3693.3Vemircopan
CAS:<p>Vemircopan is a complement factor D inhibitor.</p>Formula:C29H28BrN7O3Color and Shape:SolidMolecular weight:602.493NC318
<p>NC318 is a humanized antibody targeting Siglec-15/CD33L3 for the study of non-small cell lung cancer.</p>Purity:98.6% (SDS-PAGE); 99% (SEC-HPLC) - 98.6% (SDS-PAGE); 99% (SEC-HPLC)Color and Shape:Odour LiquidDamnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formula:C16H12O5Color and Shape:SolidMolecular weight:284.267cyclo(RLsKDK) TFA
<p>Cyclo(RLsKDK) TFA (BK-1361 TFA) is a cyclic peptide and selective ADAM8 metalloproteinase inhibitor, used in research on inflammation and cancer.</p>Formula:C33H58F3N11O11Purity:98.54%Color and Shape:SolidMolecular weight:841.88TBK1/IKKε-IN-6
CAS:<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Formula:C31H36F2N8O4Color and Shape:SolidMolecular weight:622.678DOPAL
CAS:<p>DOPAL, a neurotoxic aldehyde from dopamine metabolism, is linked to Parkinson's and can convert to DOPAC or DOPET.</p>Formula:C8H8O3Color and Shape:SolidMolecular weight:152.15MAPK-IN-4
<p>MAPK-IN-4 (Compound c1) is an orally active anti-inflammatory agent that inhibits the expression and release of pro-inflammatory cytokines IL-6 and TNF-α induced by LPS. It interacts with IRAK4 to exert its anti-inflammatory effects by inhibiting the MAPK pathway.</p>Color and Shape:Odour SolidFITC-labeled Agatolimod sodium
<p>FITC-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Color and Shape:Odour SolidChitoheptaose heptahydrochloride
CAS:<p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>Formula:C42H80ClN7O29Color and Shape:SolidMolecular weight:1182.57HuMax-IL8
<p>HuMax-IL8 (MDX 018) is a humanized anti-IL-8 monoclonal antibody for the study of metastatic or unresectable solid tumors.</p>Purity:98.8% (SDS-PAGE); 97.4% (SEC-HPLC) - 98.8% (SDS-PAGE); 97.4% (SEC-HPLC)Color and Shape:Odour LiquidEfmarodocokin alfa
CAS:<p>Efmarodocokin alfa, IL-22/IgG4 fusion protein, activates IL-22 pathways, researched for severe COVID-19 pneumonia.</p>Color and Shape:LiquidIFN-α Receptor Recognition Peptide 1
CAS:<p>IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.</p>Formula:C35H59N13O12SPurity:98%Color and Shape:SolidMolecular weight:885.99Septeremophilane E
<p>Septeremophilane E, from Septoria rudbeckiae fungus, inhibits NO production.</p>Formula:C21H26O5Color and Shape:SolidMolecular weight:358.43ROS inducer 6
<p>ROS inducer 6 (compound 9) acts as a reactive oxygen species (ROS) inducer by depleting intracellular glutathione, thereby functioning as an antitumor agent.</p>Formula:C32H26N2O3Color and Shape:SolidMolecular weight:486.56Neuroprotective agent 8
<p>Neuroprotective agent 8 (compound AA-9) is an orally active neuroprotective agent that functions through antioxidant stress reduction and anti-inflammatory mechanisms. In a rat model of MCAO ischemic stroke, it activates PGC-1α and inhibits the NLRP3 inflammasome.</p>Color and Shape:Odour Solid17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
CAS:<p>DPA metabolite 17-oxo-DPA, found in fish oil, spurs antioxidant genes, modulates inflammation, and activates PPARγ (EC50 ≈ 200 nM).</p>Formula:C22H32O3Color and Shape:SolidMolecular weight:344.495WAY-605471
CAS:<p>WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.</p>Formula:C14H15NO3S2Purity:99.62%Color and Shape:SolidMolecular weight:309.4ODN 2395
CAS:<p>ODN 2395, a class C oligodeoxynucleotide and TLR9 agonist, serves as a vaccine adjuvant. Its sequence is 5'-tcgtcgttttcggcgc:gcgccg-3' [1].</p>Color and Shape:SolidMolecular weight:7035RC529-MDP
<p>RC529-MDP is an immunological adjuvant that couples Toll-like receptors (TLR4a) and NOD-like receptors (NOD2a) to enhance the innate immune response through the TLR4 and NOD2 signaling pathways. In mouse models, RC529-MDP induces high levels of the cytokine interleukin-related factor (IL-6), highlighting its immunostimulatory activity. Additionally, when injected into mice models with ovalbumin (OVA), RC529-MDP elevates OVA-specific antibody responses, T cell responses, and the proportion of memory T cells.</p>Formula:C118H215N10O28PColor and Shape:SolidMolecular weight:2252.99JH-FK-08
<p>JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.</p>Formula:C45H73N3O13Color and Shape:SolidMolecular weight:864.073Ripertamab
CAS:<p>Ripertamab (SCT-400) is a recombinant human-mouse chimeric monoclonal antibody that targets CD20 and is cytotoxic.</p>Purity:97.8% (SEC-HPLC) - 97.8% (SEC-HPLC)Color and Shape:Liquid3-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Formula:C30H44O7SColor and Shape:SolidMolecular weight:548.73Biotinoyl tripeptide-1
CAS:<p>Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.</p>Formula:C24H38N8O6SPurity:98%Color and Shape:SolidMolecular weight:566.67Bavunalimab
CAS:<p>Bavunalimab: bispecific anti-CTLA-4/LAG-3 antibody, T-cell activator in NSG mice, for cancer research.</p>Color and Shape:LiquidLadanetin-6-O-β-D-glucopyranoside
CAS:<p>Ladanetin-6-O-β-D-glucopyranoside, an active flavonoid, exhibits antioxidative effects and has potential for research into cardioprotective effects [1].</p>Formula:C22H22O11Color and Shape:SolidMolecular weight:462.4SARS-CoV-2-IN-107
<p>SARS-CoV-2-IN-107 (Compound A7) is an inhibitor of SARS-CoV-2 3CLpro, with an IC50 of 261.3 nM. It inhibits the replication of SARS-CoV-2, exhibiting an EC50 of 11.7 μM. Additionally, SARS-CoV-2-IN-107 demonstrates anti-inflammatory activity in LPS-stimulated RAW264.7 macrophages, with a NO inhibition rate of 68.6%.</p>Formula:C15H11FO4Color and Shape:SolidMolecular weight:274.244IL-17A inhibitor 2
CAS:<p>IL-17A inhibitor 2 is an IL-17A inhibitor for treating psoriasis, rheumatoid arthritis, and multiple sclerosis.</p>Formula:C24H25F7N8O4Color and Shape:SolidMolecular weight:622.505CAY10512
CAS:<p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>Formula:C15H13FOColor and Shape:SolidMolecular weight:228.266Romilkimab
CAS:<p>Romilkimab (SAR156597) is a chimeric humanized immunoglobulin (Ig) antibody designed to specifically target interleukins 4 and 13 (IL-4 and IL-13) [1].</p>Color and Shape:LiquidCLIP (86-100)
CAS:<p>Amino acids 86-100 of CLIP, replaced by DM to allow MHC class II to present foreign peptides, triggering immune response.</p>Formula:C72H128N20O19S3Purity:98%Color and Shape:SolidMolecular weight:1674.1Factor B-IN-1
CAS:<p>Factor B-IN-1 is a Factor B inhibitor.</p>Formula:C19H16N4O2Color and Shape:SolidMolecular weight:332.3559PROTAC IRAK4 degrader-5
CAS:<p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>Formula:C41H40F3N11O9Color and Shape:SolidMolecular weight:887.834Mifamurtide sodium
CAS:<p>Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.</p>Formula:C59H108N6NaO19PPurity:98%Color and Shape:SolidMolecular weight:1259.48KTX-955
CAS:<p>KTX-955, a potent IRAK4 degrader, exhibits DC50 values of 5 nM for IRAK4 and 130 nM for Ikaros. It is primarily utilized in anticancer research [1] [2].</p>Formula:C46H51F3N8O7Color and Shape:SolidMolecular weight:884.94STING agonist-17
CAS:<p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>Formula:C43H53N13O8Color and Shape:SolidMolecular weight:879.96MCC950
CAS:<p>MCC950 (CP-456773) is a NLRP3 inflammasome inhibitor (IC50=7.5-8.1 nM). MCC950 can be used to treat inflammatory diseases. High-Quality, Low-Cost!</p>Formula:C20H24N2O5SPurity:97% - 98%Color and Shape:SolidMolecular weight:404.48CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Color and Shape:SolidNosantine racemate
CAS:<p>Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).</p>Formula:C14H22N4O2Purity:98%Color and Shape:SolidMolecular weight:278.35Nω-Propyl-L-arginine
CAS:<p>Nω-Propyl-L-arginine, a powerful and specific inhibitor of neuronal nitric oxide synthase (nNOS), effectively inhibits nNOS with a Ki of 57 nM.</p>Formula:C9H20N4O2Color and Shape:SolidMolecular weight:216.28Bivalirudin TFA
CAS:<p>Bivalirudin TFA, a 20-residue synthetic peptide, reversibly inhibits thrombin, affecting platelet aggregation and thrombin generation.</p>Formula:C98H138N24O33·C2HF3O2Color and Shape:SolidMolecular weight:2294.34G3-C12
CAS:<p>G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.</p>Formula:C74H115N23O23S2Purity:98%Color and Shape:SolidMolecular weight:1758.99PMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Formula:C47H63F3N10O8Color and Shape:SolidMolecular weight:953.06Bengamide B
CAS:<p>Potent NF-κB inhibitor, IC50 at 85 nM. Reduces IκBα phosphorylation, NO, TNF-α, IL-6, MCP. Inhibits HeLa, HCT116 cell growth. Anti-inflammatory, antitumor.</p>Formula:C32H58N2O8Color and Shape:SolidMolecular weight:598.81
