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MAPK

MAPK

MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.

Found 885 products of "MAPK"

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  • SOS1-IN-5
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    SOS1-IN-5

    CAS:
    <p>SOS1-IN-5, a potent pyrimidine inhibitor, disrupts RAS-SOS1, blocking KRAS activation.</p>
    Formula:C26H31F3N4O5
    Color and Shape:Solid
    Molecular weight:536.54

    Ref: TM-T63781

  • ZG1077
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    ZG1077

    CAS:
    <p>ZG1077, a covalent KRAS G12C inhibitor, is utilized in non-small cell lung cancer (NSCLC) research.</p>
    Formula:C33H33F2N5O5S
    Color and Shape:Solid
    Molecular weight:649.71

    Ref: TM-T73510

  • KRAS G12C mutant protein inhibitor A-1
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    KRAS G12C mutant protein inhibitor A-1

    CAS:
    <p>KRAS G12C mutant protein inhibitor A-1 can be used in studies about Ras.</p>
    Formula:C31H26ClF4N7O2
    Color and Shape:Solid
    Molecular weight:640.03

    Ref: TM-T77805

  • ERK1/2 inhibitor 9
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    ERK1/2 inhibitor 9

    CAS:
    <p>ERK1/2 Inhibitor 9 (Probe 1), a covalent antagonist of ERK1/2, exhibits sub-micromolar efficacy in cellular assays (A375 GI50=0.47 μM) and facilitates the</p>
    Formula:C31H32ClN7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:586.08

    Ref: TM-T78190

  • Org OD 02-0
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    Org OD 02-0

    CAS:
    <p>10-Ethenyl-19-norprogesterone (Org OD 02-0) is a selective agonist for the membrane progesterone receptor α (mPRα) with an IC50 of 33.9 nM, known to activate</p>
    Formula:C22H30O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:326.47

    Ref: TM-T81598

  • FGTI-2734
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    FGTI-2734

    CAS:
    <p>FGTI-2734, a dual FT/GGT-1 inhibitor (IC50: 250/520 nM), blocks KRAS membrane binding and curbs KRAS-driven pancreatic cancer.</p>
    Formula:C26H31FN6O2S
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:510.63

    Ref: TM-T11282

  • GNE 220
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    GNE 220

    CAS:
    <p>GNE-220 is a potent and selective inhibitor of MAP4K4 (IC50: 7 nM).</p>
    Formula:C25H26N8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.53

    Ref: TM-T11443

  • HPK1-IN-12
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    HPK1-IN-12

    CAS:
    <p>HPK1-IN-12 is a potent inhibitor of HPK1. HPK1-IN-12 has potential for the study of HPK1-related diseases.</p>
    Formula:C25H24FN5O2
    Color and Shape:Solid
    Molecular weight:445.49

    Ref: TM-T62628

  • XRP44X
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    XRP44X

    CAS:
    <p>XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.</p>
    Formula:C21H21ClN4O
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:380.87

    Ref: TM-T20759

  • KRAS G12D mutation regulator 4
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    KRAS G12D mutation regulator 4

    CAS:
    <p>KRAS G12D mutation regulator 4 can be used in studies about Ras.</p>
    Formula:C33H33FN6O2
    Color and Shape:Solid
    Molecular weight:564.65

    Ref: TM-T77804

  • ERK-IN-2 free base
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    ERK-IN-2 free base

    CAS:
    <p>ERK-IN-2 free base inhibits ERK2 (IC50: 1.8 nM); potential off-target effects at &gt;10 μM.</p>
    Formula:C16H17N5O2
    Color and Shape:Solid
    Molecular weight:311.34

    Ref: TM-T72517

  • DT-061
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    DT-061

    CAS:
    <p>DT-061 is an orally bioavailable protein phosphatase 2A (PP2A) activator. It could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis.</p>
    Formula:C25H23F3N2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:520.52

    Ref: TM-T10060L

  • KRAS G12C inhibitor 16
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    KRAS G12C inhibitor 16

    CAS:
    <p>KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor.</p>
    Formula:C24H21ClFN3O3
    Purity:97.84%
    Color and Shape:Solid
    Molecular weight:453.89

    Ref: TM-T11770

  • CymitQuimica logo
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    CXJ-2

    CAS:
    <p>CXJ-2, a cyclic peptide, binds EDPs, inhibits PI3K/ERK, and reduces hepatic cell growth/migration, offering antifibrotic effects.</p>
    Formula:C55H87N15O22
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1310.37

    Ref: TM-T74782

  • KRAS G12C inhibitor 58
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    KRAS G12C inhibitor 58

    CAS:
    <p>KRAS G12C inhibitor 58 is utilized in cancer research as an inhibitor of the KRAS G12C mutation [1].</p>
    Formula:C51H64ClF4N9O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1074.62

    Ref: TM-T79057

  • HPK1-IN-27
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    HPK1-IN-27

    CAS:
    <p>HPK1-IN-27 inhibits HPK1 (MAP4K1), a kinase with potential for cancer treatment, per patent WO2019016071A1, compound 38.</p>
    Formula:C26H23F3N4O4
    Color and Shape:Solid
    Molecular weight:512.48

    Ref: TM-T63541

  • KRAS inhibitor FB9
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    KRAS inhibitor FB9

    CAS:
    <p>KRAS inhibitor FB9 can be used in studies about Ras.</p>
    Formula:C23H21ClF4N2O5
    Color and Shape:Solid
    Molecular weight:516.87

    Ref: TM-T77806

  • KRAS G12D modulator-1
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    KRAS G12D modulator-1

    CAS:
    <p>KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and is</p>
    Formula:C30H36FN5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:549.64

    Ref: TM-T79072

  • MS934
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    MS934

    CAS:
    <p>MS934, a novel VHL-recruiting MEK 1/2 degrader, exhibits potent anti-proliferative effects on HT-29 cell growth, achieving a GI50 of 0.023 μM.</p>
    Formula:C52H69F3IN7O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1104.11

    Ref: TM-T79143

  • B-Raf IN 16
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    B-Raf IN 16

    CAS:
    <p>B-Raf IN 16, a BRAF inhibitor, belongs to cyclic iminopyrimidine derivatives and can be used for cancer or tumour research.</p>
    Formula:C20H19N5O3S
    Purity:99.31% - 99.78%
    Color and Shape:Solid
    Molecular weight:409.46

    Ref: TM-T79830