p38 MAPK
p38 MAPKs are a subgroup of MAPKs that respond to stress signals and are involved in the regulation of inflammation, cell differentiation, apoptosis, and autophagy. p38 MAPK signaling is crucial in immune responses and is implicated in various diseases, including chronic inflammatory conditions, cancer, and neurodegenerative disorders. At CymitQuimica, we provide a comprehensive range of p38 MAPK inhibitors and modulators to support your research in inflammation, stress response, and therapeutic development.
Found 117 products of "p38 MAPK"
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BMS582949
CAS:<p>BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.</p>Formula:C22H26N6O2Purity:98.11%Color and Shape:SolidMolecular weight:406.48Pexmetinib
CAS:<p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>Formula:C31H33FN6O3Purity:99.07% - 99.66%Color and Shape:SolidMolecular weight:556.63Dehydrocorydaline nitrate
CAS:<p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>Formula:C22H24N2O7Purity:99.79% - 99.92%Color and Shape:SolidMolecular weight:428.44VX-702
CAS:<p>VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.</p>Formula:C19H12F4N4O2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:404.32TLC1566-0618
CAS:<p>TLC1566-0618 shows antitumor activity and targets stat.</p>Formula:C20H15NO3S3Purity:98%Color and Shape:SolidMolecular weight:413.53(S)-(-)-PH-797804
CAS:Controlled ProductFormula:C19H38N5O5Color and Shape:NeatMolecular weight:416.536LY 294002 Hydrochloride
CAS:Controlled Product<p>Applications LY 294002 Hydrochloride is a highly selective inhibitor of Phosphatidylinositol 3-kinase (PI3K). It is a salt analogue of LY 294002 (L486590).<br>References Lin, C., et. al.: J. Biol. Chem., 286, 10483 (2011); Cao, H., et. al.: J. Biol. Chem., 288, 30399 (2013);<br></p>Formula:C19H17NO3·(HCl)Color and Shape:NeatMolecular weight:343.8SB 706504
CAS:<p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>Formula:C24H19F3N8OPurity:98.686%Color and Shape:SolidMolecular weight:492.46AL 8697
CAS:<p>AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.</p>Formula:C21H21F3N4OPurity:99.55% - 99.89%Color and Shape:SolidMolecular weight:402.41PF-05381941
CAS:<p>PF-05381941 is a selective and potent dual inhibitor of TAK1 and p38α that inhibits the kinase activity of TAK1 by binding to its active site.</p>Formula:C27H26N6O2Purity:98.04%Color and Shape:SolidMolecular weight:466.53EO-1606
CAS:<p>EO-1606 is a p38MAP kinase inhibitor with anti-inflammatory activity and may be used in studies of Alzheimer;s disease and dermatitis.</p>Formula:C21H17ClFNOPurity:98.28% - 98.84%Color and Shape:SolidMolecular weight:353.82p38α inhibitor 4
CAS:<p>p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.</p>Formula:C14H7F6N3OPurity:99.69%Color and Shape:SolidMolecular weight:347.215UR13870
CAS:<p>UR-13870 (Org 48762-0) is a p38 MAPK inhibitor that prevents bone damage in collagen-induced arthritis in mice.</p>Formula:C24H16F2N4Purity:99.18% - >99.99%Color and Shape:SolidMolecular weight:398.41AKP-001
CAS:<p>AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in the study of immune and digestive disorders.</p>Formula:C21H13ClF2N4O2Purity:99.50% - 99.92%Color and Shape:SolidMolecular weight:426.8p38 MAPK Inhibitor
CAS:<p>p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.</p>Formula:C20H13ClFN3OPurity:99.91%Color and Shape:SolidMolecular weight:365.79SB-747651A Dihydrochloride
CAS:<p>SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.</p>Formula:C16H24Cl2N8OPurity:98.05%Color and Shape:SolidMolecular weight:415.32Org OD 02-0
CAS:<p>10-Ethenyl-19-norprogesterone (Org OD 02-0) is a selective agonist for the membrane progesterone receptor α (mPRα) with an IC50 of 33.9 nM, known to activate</p>Formula:C22H30O2Purity:98%Color and Shape:SolidMolecular weight:326.47p38-α MAPK-IN-1
CAS:<p>p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.</p>Formula:C27H35N5O3Purity:99.93%Color and Shape:SolidMolecular weight:477.6PLK1/p38γ-IN-1
CAS:<p>PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellular</p>Formula:C21H26ClN3O2Purity:98%Color and Shape:SolidMolecular weight:387.9
