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Calcium Channel

Calcium Channel

Calcium channels are membrane proteins that regulate the flow of calcium ions into and out of cells, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calcium channel activity is associated with conditions such as hypertension, cardiac arrhythmias, and neurological disorders. At CymitQuimica, we provide a wide selection of calcium channel modulators to support your research in cardiovascular health, neurobiology, and signal transduction.

Found 493 products of "Calcium Channel"

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  • Cis-22a

    CAS:
    <p>Cis-22a: selective TRPV6 inhibitor (IC50=0.32μM), halts T47D breast cancer cell growth.</p>
    Formula:C24H30F3N3O2
    Purity:99.07%
    Color and Shape:Solid
    Molecular weight:449.51
  • EMD57033

    CAS:
    <p>EMD57033 activates cardiac troponin C, enhances Ca2+ sensitivity to boost heart contraction.</p>
    Formula:C22H23N3O4S
    Purity:99.72% - >99.99%
    Color and Shape:Solid
    Molecular weight:425.5
  • Reldesemtiv

    CAS:
    <p>Reldesemtiv (CK-2127107) boosts exercise capacity, targeting fast muscle troponin, EC50 3.4 μM.</p>
    Formula:C19H18F2N6O
    Purity:97.27%
    Color and Shape:Solid
    Molecular weight:384.38
  • Calcium channel-modulator-1

    CAS:
    <p>Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.</p>
    Formula:C26H24Cl2N2O7S
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:579.45
  • AY 77

    CAS:
    <p>AY 77: Potent, selective PAR2 agonist, favors Ca2+ (ec50=40nM) &amp; ERK1/2 (ec50=2μM), boosts breast cancer cell migration.</p>
    Formula:C21H32N4O4
    Purity:99.7%
    Color and Shape:Solid
    Molecular weight:404.5
  • Fluspirilene

    CAS:
    <p>Fluspirilene is a long-acting antipsychotic for schizophrenia, inhibiting L-type calcium channels (IC50: 0.03 μM).</p>
    Formula:C29H31F2N3O
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:475.57
  • Bupivacaine hydrochloride monohydrate

    CAS:
    <p>Bupivacaine hydrochloride monohydrate is an NMDA receptor inhibitor that inhibits SCN5A channels and is commonly used in the study of chronic pain.</p>
    Formula:C18H31ClN2O2
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:342.9
  • SR 33805 oxalate

    CAS:
    <p>Ca2+ channel antagonist</p>
    Formula:C34H42N2O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:654.77
  • IAA65

    CAS:
    <p>IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].</p>
    Formula:C16H13F6NO2
    Color and Shape:Solid
    Molecular weight:365.27
  • CCR4 antagonist 2

    CAS:
    <p>CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg</p>
    Formula:C26H28Cl2N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:511.45
  • Cav 2.2/3.2 blocker 1


    <p>Compound 9e is a Cav 2.2/3.2 blocker; IC50: 1.22 μM &amp; 80 μM, respectively; penetrates CNS.</p>
    Formula:C28H30N2O3
    Color and Shape:Solid
    Molecular weight:442.55
  • (rel)-Mirogabalin

    CAS:
    <p>(rel)-Mirogabalin ((rel)-DS5565) is an inhibitor of voltage-dependent calcium channels, specifically targeting the α2δ-1 subunit.</p>
    Formula:C12H19NO2
    Color and Shape:Solid
    Molecular weight:209.28
  • NNC 55-0396

    CAS:
    <p>NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.</p>
    Formula:C30H40Cl2FN3O2
    Purity:99.00%
    Color and Shape:Solid
    Molecular weight:564.56
  • SB-423557

    CAS:
    <p>SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nM</p>
    Formula:C28H36N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:464.60
  • Mibefradil

    CAS:
    <p>Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).</p>
    Formula:C29H38FN3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:495.63
  • Sesamodil

    CAS:
    <p>Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.</p>
    Formula:C29H32N2O6S
    Purity:98.58% - 99.01%
    Color and Shape:Solid
    Molecular weight:536.64
  • Cav 3.2 inhibitor 1


    <p>Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.</p>
    Formula:C32H39N3O
    Color and Shape:Solid
    Molecular weight:481.67
  • MP-010

    CAS:
    <p>MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.</p>
    Formula:C14H20N4O2S
    Color and Shape:Solid
    Molecular weight:308.399
  • Cav 3.2 inhibitor 3


    <p>Cav 3.2 inhibitor 3 is a potent inhibitor of the Cav3.2 T-type Ca2+channel (IC50: 0.1534 μM) and has a low binding affinity for D2 receptors.</p>
    Formula:C32H37N3O2
    Color and Shape:Solid
    Molecular weight:495.66
  • PD-217014

    CAS:
    <p>PD-217014 is an α2δ ligand that exhibits visceral analgesic activity and can suppress visceral hypersensitivity. Its antihyperalgesic effects are dose-dependent.</p>
    Formula:C10H17NO2
    Color and Shape:Solid
    Molecular weight:183.25