Metabolism

<p>B4GALT1 (LgtB) is key in biochemical research, bonding UDP-galactose and N-acetylglucosamine to form Galβ1-4GlcNAc.</p>

<p>Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.</p>

<p>Cholesteryl arachidonate is a human endogenous metabolite.</p>

<p>Ercalcitriol, active Vitamin D2 metabolite, boosts immunity by regulating CAMP and DEFB4 genes against infections.</p>

<p>CgtB enzyme, needed for GM1-like LOS SIAL, catalyzes galactose addition in biochemical studies.</p>

<p>2-NP-AHD, derived from AHD/nitrofuran metabolite, indicates illegal nitrofuran use.</p>

<p>Saccharopine hydrochloride, from lysine degradation, disrupts mitochondria and hinders development.</p>

<p>Naphthol AS-GR phosphate disodium: intense green fluorescent probe for phosphatases in histochemistry.</p>

<p>Pristanic acid, found in blood, aids in studying Alpha Methylacyl CoA Racemase Deficiency and Zellweger Syndrome.</p>

<p>Burnettramic acid A aglycone, from A. burnettii, has anticancer properties; cytotoxic to NS-1 cells (IC50 = 8.4 μg/ml), not to fibroblasts (&gt;100 μg/ml).</p>

<p>UDP-3-O-acyl-GlcNAc is an E. coli metabolite for KDO biosynthesis.</p>

<p>11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13</p>

<p>JTV-519 Formate is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA).</p>

<p>Adenylosuccinic acid, orally active, is a purine ribonucleotide involved in nucleotide metabolism, may aid in DMD studies.</p>

<p>Calcium gluconate monohydrate is a useful organic compound for research related to life sciences. The catalog number is T35350 and the CAS number is 66905-23-5.</p>

<p>6-Ethyl-2,7-dimethoxyjuglone is a metabolite isolated from freshwater fungi [1] .</p>

<p>CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.</p>

<p>α-Glucosidase-IN-82 (compound 8l) is a potent inhibitor of α-glucosidase, with an IC50 value of 13.66 μM. Its inhibitory activity is 52 times greater than that of Acarbose.</p>

<p>ISM012-042 is an orally active inhibitor of PHD1 and PHD2, with IC50 values of 1.9 and 2.5 nM, respectively. At a concentration of 2.5 μM, ISM012-042 protects Caco-2 cells from DSS-induced barrier damage. Additionally, in LPS-induced bone marrow-derived dendritic cells (BMDC) from mice, ISM012-042 exhibits anti-inflammatory properties by dose-dependently reducing the expression of IL-12 subunit IL-12p35 and TNF. It also restores intestinal barrier function and alleviates intestinal inflammation in various experimental colitis models. ISM012-042 is useful for studying intestinal mucosal repair and immune disorders.</p>

<p>Lunine is a bioactive chemical.</p>