Microbiology/Virology
Microbiology and virology inhibitors are compounds that target microorganisms, including bacteria, viruses, and fungi, disrupting their growth, replication, or survival. These inhibitors are essential for studying microbial pathogenesis, understanding resistance mechanisms, and developing new antimicrobial and antiviral therapies. Inhibitors in this category are used to combat infectious diseases, explore microbial ecology, and investigate host-pathogen interactions. At CymitQuimica, we provide a broad selection of high-quality microbiology and virology inhibitors to support your research in infectious diseases, microbiology, and virology.
Subcategories of "Microbiology/Virology"
- Antibacterial(2,949 products)
- Antibiotic(918 products)
- Antifection(23 products)
- DHFR(32 products)
- DNA/RNA Synthesis(706 products)
- HBV(176 products)
- HIV Protease(447 products)
- HSV(91 products)
- Integrase(2 products)
- Ribosome(13 products)
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Found 5832 products of "Microbiology/Virology"
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GSK_WRN4
CAS:<p>GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer research</p>Formula:C16H20N2O4SPurity:99.95%Color and Shape:SolidMolecular weight:336.41PLpro-IN-6
CAS:<p>PLpro-IN-6 (compound 6) serves as an inhibitor for the papain-like protease (PLpro), demonstrating potent activity with an IC 50 of 0.019 μM against the SARS-CoV-2 PLpro enzyme.</p>Formula:C29H30N6OColor and Shape:SolidMolecular weight:478.59Lamivudine, (+/-)-trans-
CAS:<p>Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.</p>Formula:C8H11N3O3SPurity:98%Color and Shape:SolidMolecular weight:229.26GC373
CAS:<p>GC373, an effective inhibitor of the SARS-CoV-2 M pro, impedes virus replication, exhibiting an inhibition concentration (IC 50) of 0.4 μM. This compound is valuable for use in anti-COVID-19 research.</p>Formula:C21H29N3O5Color and Shape:SolidMolecular weight:403.47LN002
CAS:<p>LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.</p>Formula:C22H15N7Color and Shape:SolidMolecular weight:377.40Fabimycin
CAS:<p>Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.</p>Formula:C23H25ClN4O3Color and Shape:SolidMolecular weight:440.92NBD-14189
CAS:<p>NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).</p>Formula:C18H16F4N4O2SColor and Shape:SolidMolecular weight:428.40Enzyme-IN-3 disodium
CAS:<p>Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.</p>Formula:C20H13N3Na2O8S2Color and Shape:SolidMolecular weight:533.442HBV-IN-19 TFA
CAS:<p>HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.</p>Formula:C26H31F3N2O8Color and Shape:SolidMolecular weight:556.53UNI418
CAS:<p>UNI418 is a dual inhibitor targeting PIKfyve and PIP5K1C, exhibiting antiviral activity against SARS-CoV-2 (EC50=1.4 μM). It inhibits the endocytosis of the virus mediated by ACE2 by suppressing PIP5K1C (IC50=60.1 nM; Kd=61 nM). Additionally, UNI418 impedes the entry of SARS-CoV-2 into host cells by inhibiting the proteolytic activation regulated by PIKfyve (Kd=0.78 nM).</p>Formula:C22H16N6Color and Shape:SolidMolecular weight:364.40Anti-Influenza agent 3
<p>Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).</p>Formula:C16H22ClNOSColor and Shape:SolidMolecular weight:311.87PLpro-IN-5
CAS:<p>PLpro-IN-5 (compound 21), serving as a PLPro protease inhibitor, boasts an IC50 of 91.14 nM. This compound exhibits a broad-spectrum antivirus efficacy, particularly effective against SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formula:C26H33N3OColor and Shape:SolidMolecular weight:403.56ZINC000104379474
<p>ZINC000104379474 is a compound that targets SARS-CoV-2 endoribonuclease.</p>Formula:C27H33N3O10Color and Shape:SolidMolecular weight:559.57Neocryptolepine-Cl
CAS:<p>Neocryptolepine-Cl (compound Z24) is an inhibitor of Bcthi4, demonstrating excellent antifungal activity against B. cinerea, with an EC50 value of 0.56 μg/mL.</p>Formula:C16H11ClN2Color and Shape:SolidMolecular weight:266.725Cephalosporin C
CAS:<p>Cephalosporin C exhibits relatively weak resistance to Gram-positive and Gram-negative bacteria. It is stable against penicillinase, but can be decomposed by cephalosporinase. When hydrolyzed to remove its side chain, it yields 7-amino-cefenoic acid (7-ACA), which is an essential raw material for the production of semisynthetic cephalosporins.</p>Formula:C16H21N3O8SColor and Shape:SolidMolecular weight:415.418Colistin adjuvant-2
<p>Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].</p>Formula:C14H7Cl2F3N2OColor and Shape:SolidMolecular weight:347.12ZK-316
CAS:<p>ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.</p>Formula:C27H22D6N6O3S2Color and Shape:SolidMolecular weight:554.72Cefoxazole
CAS:<p>Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.</p>Formula:C21H18ClN3O7SColor and Shape:SolidMolecular weight:491.902NBTIs-IN-5
CAS:<p>NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.</p>Formula:C24H25F3N4O2Color and Shape:SolidMolecular weight:458.48Telinavir
CAS:<p>Telinavir (SC-52151) is a potent and selective inhibitor of HIV protease. It effectively inhibits both HIV-1 and HIV-2, as well as lymphotropic, monocytotropic strains, and wild isolates of simian immunodeficiency viruses, with an EC50 of 26 ng/mL (43 nM). Telinavir shows high protein binding in human plasma and a low distribution rate in red blood cells.</p>Formula:C33H44N6O5Color and Shape:SolidMolecular weight:604.74NITD-688
CAS:<p>NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.</p>Formula:C25H32N4O3S2Color and Shape:SolidMolecular weight:500.68Antifungal agent 127
CAS:<p>Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.</p>Formula:C13H12ClN3OColor and Shape:SolidMolecular weight:261.707XR8-89
CAS:<p>XR8-89, a potent PLpro inhibitor (IC50=0.1μM), blocks SARS-CoV-2 replication; useful for research.</p>Formula:C29H36N4O2SColor and Shape:SolidMolecular weight:504.69TCMDC-125431
<p>TCMDC-125431 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystals.</p>Formula:C25H27N3O2SColor and Shape:SolidMolecular weight:433.57BMIM-TFSI
CAS:<p>BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.</p>Formula:C10H15F6N3O4S2Color and Shape:SolidMolecular weight:419.364MsbA-IN-4
<p>MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).</p>Formula:C23H18Cl2FN5OColor and Shape:SolidMolecular weight:470.33Antibacterial agent 81
CAS:<p>Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.</p>Formula:C33H28N2O8Color and Shape:SolidMolecular weight:580.58Antimicrobial agent-38
CAS:<p>Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.</p>Formula:C14H11N3O4SColor and Shape:SolidMolecular weight:317.32MPro N3
CAS:<p>Mpro inhibitor blocks MHV-A29, HCoV-229E, FOPV (IC50: 2.7–8.8 μM), and SARS-CoV-2 (IC50: 16.8 μM) in plaque assays.</p>Formula:C35H48N6O8Color and Shape:SolidMolecular weight:680.79RdRP-IN-4
<p>RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.</p>Formula:C17H17Br2N3O2Color and Shape:SolidMolecular weight:455.14(E)-2,6-Di-tertbutyl-4(4-(diethylamino)styryl)pyrylium TFA
CAS:<p>(E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium TFA (Compound 4a) functions as a Gram-negative outer membrane permeabilizer by targeting Met47 in LptA to disrupt LptA/LptC interactions, exhibiting synergistic antibacterial activity. This compound, when in the form of (trifluoromethanesulfonate), enhances the efficacy of pol B against both wild-type and multi-drug resistant A. baumannii and E. coli strains. Additionally, (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) serves as an adjuvant for antibiotics combating multi-drug resistant Gram-negative bacteria.</p>Formula:C26H36F3NO4SColor and Shape:SolidMolecular weight:515.629MraY-IN-3
<p>MraY-IN-3 (12a) is a potent inhibitor of the bacterial translocase MraY (IC50: 140 μM). 46 μg/ml).</p>Formula:C35H45N3O5Color and Shape:SolidMolecular weight:587.75SARS-CoV-2-IN-24
<p>SARS-CoV-2-IN-24 blocks PLpro, altering its shape and stopping virus replication—useful for SARS-CoV-2 research.</p>Formula:C27H30N4O5Color and Shape:SolidMolecular weight:490.55HBV-IN-12
CAS:<p>HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)</p>Formula:C23H27NO8Color and Shape:SolidMolecular weight:445.46Laninamivir trifluoroacetate
CAS:<p>Laninamivir trifluoroacetate, a long-acting antiviral, treats and prevents Influenza A and B via nasal spray.</p>Formula:C15H23F3N4O9Purity:98%Color and Shape:SolidMolecular weight:460.363Glutamate-5-kinase-IN-1
<p>Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.</p>Formula:C20H18N2OColor and Shape:SolidMolecular weight:302.37HldA/E-IN-1
CAS:<p>HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, exhibiting IC50 values of 17.2 μM and 67.8 μM, respectively. This compound is utilized in research on antibacterial infections.</p>Formula:C8H17FO13P2Color and Shape:SolidMolecular weight:402.16Antibacterial agent 279
CAS:<p>Antibacterialagent 279 (compound A12) is an effective antibacterial agent. It inhibits the SOS response of Pseudomonas aeruginosa.</p>Formula:C9H11NO2SColor and Shape:SolidMolecular weight:197.25Teslexivir hydrochloride
CAS:<p>Teslexivir (BTA074) HCl inhibits HPV 6/11 by blocking E1-E2 protein interaction, vital for DNA replication. Used in condyloma research.</p>Formula:C35H37BrClN3O4Color and Shape:SolidMolecular weight:679.04Antibacterial synergist 1
<p>Compound 20P is a potent antibacterial, inhibits biofilms with IC50 4.5 μM, and reduces pyocyanin at IC50 8.6 μM.</p>Formula:C19H24N2O4Color and Shape:SolidMolecular weight:344.4HIV-1 inhibitor-52
CAS:<p>HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.</p>Formula:C46H72FNO5SColor and Shape:SolidMolecular weight:770.13Dioxidine
CAS:<p>Dioxidine is an antimicrobial agent that can inhibit bacterial growth. It is utilized in research on pyogenic infections.</p>Formula:C10H10N2O4Color and Shape:SolidMolecular weight:222.197Plm IV inhibitor-2
CAS:<p>"Plm IV inhibitor-2: Potent for Plm IV (IC50=24nM), affects Plm II/Plm I; malaria research compound."</p>Formula:C39H54N4O4Color and Shape:SolidMolecular weight:642.87(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Formula:C14H10ClN3S2Color and Shape:SolidMolecular weight:319.83D-G23
CAS:<p>D-G23 is a selective RAD52 inhibitor. It disrupts RAD52-mediated DNA repair pathways and suppresses the growth of cancer cells deficient in BRCA1 and BRCA2. D-G23 shows promise for research into homologous recombination-related cancers caused by BRCA1/2 mutations, such as hereditary breast and ovarian cancers.</p>Formula:C19H22N4O3Color and Shape:SolidMolecular weight:354.403PptT-IN-1
<p>PptT-IN-1, a potent PptT inhibitor (IC50: 2.8 μM), shows promise for tuberculosis research.</p>Formula:C18H29N5O2Color and Shape:SolidMolecular weight:347.46Benzohydroxamic acid
CAS:<p>Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.</p>Formula:C7H7NO2Color and Shape:SolidMolecular weight:137.136GSK-2878175
CAS:<p>GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Formula:C27H23BClFN2O6SPurity:98%Color and Shape:SolidMolecular weight:568.81ZIKV-IN-5
<p>ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.</p>Formula:C36H45NO4SiColor and Shape:SolidMolecular weight:583.83MT0703
CAS:<p>MT0703 is a cephalosporin antibiotic featuring an aminothiazolylglycyl moiety with a 1,5-dihydroxy-4-pyridinone-2-carbonyl group, displaying potent activity against Pseudomonas species.</p>Formula:C26H25N7O9S3Color and Shape:SolidMolecular weight:675.71Adafosbuvir
CAS:<p>Adafosbuvir has antiviral activity.</p>Formula:C22H29FN3O10PColor and Shape:SolidMolecular weight:545.457Cap-dependent endonuclease-IN-6
CAS:<p>Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.</p>Formula:C23H21N3O3SColor and Shape:SolidMolecular weight:419.5Gln-AMS TFA
<p>Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.</p>Formula:C17H23F3N8O10SColor and Shape:SolidMolecular weight:588.47RAD51-IN-5
CAS:<p>RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)</p>Formula:C26H38N4O5S2Color and Shape:SolidMolecular weight:550.73Antifungal agent 13
CAS:<p>Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.</p>Formula:C21H16ClF3N4OColor and Shape:SolidMolecular weight:432.83PptT-IN-2
<p>PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.</p>Formula:C22H29N5O2Color and Shape:SolidMolecular weight:395.5Anti-MRSA agent 23
CAS:<p>Anti-MRSA agent 23 (compound 11) is a potent agent against methicillin-resistant Staphylococcus aureus. This compound exhibits both antibacterial and antibiofilm properties. It facilitates the healing and reconstruction of MRSA-infected skin wounds by reducing bacterial load, alleviating inflammation, and promoting angiogenesis.</p>Formula:C20H17N5O3SColor and Shape:SolidMolecular weight:407.446ACSS2-IN-1
CAS:<p>ACSS2-IN-1, a potent ACSS2 inhibitor, has IC50 0.01-<1 nM; useful in cancer research.</p>Formula:C27H25ClN6O2Color and Shape:SolidMolecular weight:500.98ddCTP trisodium
<p>ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.</p>Formula:C9H13N3Na3O12P3Color and Shape:SolidMolecular weight:517.1Lentiginosine
CAS:<p>Lentiginosine is a selective amyloglucosidase inhibitor.</p>Formula:C8H15NO2Color and Shape:SolidMolecular weight:157.21AnCDA-IN-1
CAS:<p>AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.</p>Formula:C16H13ClN4O2Color and Shape:SolidMolecular weight:328.753SARS-CoV-2 3CLpro-IN-32
CAS:<p>SARS-CoV-2 3CLpro-IN-32 (compound B16) is a potent inhibitor of the SARS-CoV-2 3CLpro enzyme, with an IC50 of 0.109 μM. It also demonstrates antiviral activity against the coronavirus HCoV-OC43, with an EC50 of 1.99 μM.</p>Formula:C30H37N3O4S3Color and Shape:SolidMolecular weight:599.83(S)-Batylalcohol
CAS:<p>(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is an analogue of phosphonoformic acid (PFA) and demonstrates higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) compared to PFA. This compound is applicable in antiretroviral research.</p>Formula:C21H44O3Color and Shape:SolidMolecular weight:344.572Enantiomer of Sofosbuvir
<p>Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.</p>Formula:C22H29FN3O9PPurity:98%Color and Shape:SolidMolecular weight:529.45Cap-dependent endonuclease-IN-2
<p>Cap-dependent endonuclease-IN-2 strongly blocks influenza A virus RNA polymerase; it's a CEN inhibitor.</p>Formula:C30H24FN3O7SColor and Shape:SolidMolecular weight:589.59BAS-118
CAS:<p>BAS-118 is a benzamide derivative exhibiting antibacterial activity. For 100 randomly selected strains of Helicobacter pylori, its MIC50, MIC90, and MIC range were ≤0.003, 0.013, and ≤0.003-0.025 mg/L, respectively. BAS-118 shows potential for research as an anti-H. pylori agent.</p>Formula:C20H18N2O2Color and Shape:SolidMolecular weight:318.369trans-RdRP-IN-5
<p>Trans-RdRP-IN-5 is a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), with applications in influenza virus research.</p>Formula:C23H21N3O5Color and Shape:SolidMolecular weight:419.43Antibacterial agent 113
<p>Antibacterial agent 113 targets multiple bacteria including P. aeruginosa and E. coli, showing efficacy at MIC 15625 μM.</p>Formula:C29H18ClN5OColor and Shape:SolidMolecular weight:487.94Antimalarial agent 3
<p>Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.</p>Formula:C15H16BrN3O2Color and Shape:SolidMolecular weight:350.21GT-055
<p>GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.</p>Formula:C13H20F3N5O8SColor and Shape:SolidMolecular weight:463.39LN-439A
CAS:<p>LN-439A (compound LN-439A) is a novel BAP1 inhibitor that suppresses the growth of basal-like breast cancer by degrading KLF5.</p>Formula:C24H26FN3O4Color and Shape:SolidMolecular weight:439.48Cap-dependent endonuclease-IN-7
CAS:<p>Cap-dependent endonuclease-IN-7, a potent CEN inhibitor, blocks viral mRNA synthesis and virus spread, with research use for influenza A, B, C.</p>Formula:C36H28FN3O7SColor and Shape:SolidMolecular weight:665.69(4-Aminobenzoyl)-D-glutamic acid
CAS:<p>(4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth.</p>Formula:C12H14N2O5Color and Shape:SolidMolecular weight:266.25Antileishmanial agent-5
<p>Antileishmanial agent-4, a ribonucleoside analogue, targets L.infantum and T.cruzi with EC50s of 0.68 μM and 0.83 μM.</p>Formula:C17H17ClN4O4Color and Shape:SolidMolecular weight:376.79Cap-dependent endonuclease-IN-14
CAS:<p>Cap-dependent endonuclease-IN-14 hinders CEN and could treat influenza virus infections. (Patent CN113620948A, compound 1-c).</p>Formula:C30H23FN2O6SColor and Shape:SolidMolecular weight:558.58Antileishmanial agent-4
<p>Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].</p>Formula:C17H18N4O4Color and Shape:SolidMolecular weight:342.35NS2B/NS3-IN-2
<p>Potent dengue inhibitor NS2B/NS3-IN-2 (IC50: 6 nM, Ki: 0.66 μM) boosts cell viability, non-toxic.</p>Formula:C24H21N3O5SColor and Shape:SolidMolecular weight:463.51FWM-1
<p>FWM-1 blocks SARS-CoV-2 NSP13, hinders ATP binding, with -328.6 kcal/mol binding energy.</p>Formula:C15H11ClN4O4S2Color and Shape:SolidMolecular weight:410.86Purine phosphoribosyltransferase-IN-2
<p>Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.</p>Formula:C11H15N5Na4O10P2Color and Shape:SolidMolecular weight:531.17Triazophos
CAS:<p>Triazophos is a non-systemic pesticide that acts as an acetylcholinesterase (AChE) inhibitor, forming a covalent and irreversible bond with the acetylcholine binding site. This action blocks the hydrolysis of acetylcholine, leading to increased excitability. It is effective against a wide range of soil insects and mites, including aphids, thrips, midges, beetles, lepidopteran larvae, mole crickets, and red spiders. Triazophos is suitable for use on various crops such as ornamental plants, cotton, rice, corn, soybeans, oil palm, olives, and coffee.</p>Formula:C12H16N3O3PSColor and Shape:SolidMolecular weight:313.31Pyriftalid
CAS:<p>Pyriftalid is a novel insecticide known for its potent inhibitory activity against a variety of pests. It is widely utilized in agriculture to effectively manage crop pests, thereby enhancing both the yield and quality of crops. Additionally, research is exploring the use of Pyriftalid in boosting plant resistance to pests and diseases.</p>Formula:C15H14N2O4SColor and Shape:SolidMolecular weight:318.35Trypanothione synthetase-IN-4
<p>Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).</p>Formula:C29H52INO2Color and Shape:SolidMolecular weight:573.63FPI-1465
CAS:<p>FPI-1465: Dual serine-β-lactamase & PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.</p>Formula:C11H18N4O7SColor and Shape:SolidMolecular weight:350.35Antibacterial agent 262
CAS:<p>Antibacterialagent 262 (compound A23) is a potent antibacterial agent that inhibits the activity of Xanthomonas oryzae pv oryzae. It also disrupts the integrity of bacterial cell membranes by preventing the formation of biofilms of Xanthomonas oryzae pv oryzae.</p>Formula:C17H18F2N6O4S3Color and Shape:SolidMolecular weight:504.5545-Iminodaunorubicin hydrochloride
CAS:<p>5-Iminodaunorubicin HCl: quinone-modified anthracycline with antitumor properties, induces DNA breaks in cancer cells.</p>Formula:C27H31ClN2O9Color and Shape:SolidMolecular weight:563.00RAD51-IN-7
CAS:<p>RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)</p>Formula:C25H31N5O4S2Color and Shape:SolidMolecular weight:529.67MK-8876
CAS:<p>MK-8876 is an Inhibitor of HCV NS5B Site D.</p>Formula:C32H24F2N4O5SPurity:98%Color and Shape:SolidMolecular weight:614.62Fipravirimat
CAS:<p>Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.</p>Formula:C43H67FN2O4SColor and Shape:SolidMolecular weight:727.07DC-159a
CAS:<p>DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.</p>Formula:C21H23F2N3O40·5H2OColor and Shape:SolidMolecular weight:428.4295Anticaries agent-1
CAS:<p>Anticaries agent-1 (Compound 21b) is utilized as an anticaries agent. It effectively inhibits biofilm formation with an IC50 of 77 μM and restricts the growth of S. mutans.</p>Formula:C15H12O4Color and Shape:SolidMolecular weight:256.253(R)-ZG197
<p>(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.</p>Formula:C28H35F3N4O3Color and Shape:SolidMolecular weight:532.6Glutamate-5-kinase-IN-2
<p>Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.</p>Formula:C17H10ClFN2Color and Shape:SolidMolecular weight:296.73DXR-IN-3
CAS:<p>DXR-IN-3 is an anti-Toxoplasma DXR inhibitor. It exhibits in vitro activity against the TgDXR enzyme, with an IC50 value of 0.62 μM and a Ki value of 0.19 μM. Furthermore, DXR-IN-3 can inhibit the proliferation of Toxoplasma, displaying an IC50 value of 5.46 μM.</p>Formula:C10H12Cl2NO5PSColor and Shape:SolidMolecular weight:360.15SARS-CoV-2 nsp14-IN-2
<p>SARS-CoV-2 nsp14-IN-2: Strong Nsp14 methyltransferase inhibitor (IC50: 0.09 μM), potential for COVID-19 research.</p>Formula:C21H21N5O5SColor and Shape:SolidMolecular weight:455.49Streptothricin F
CAS:<p>Streptothricin F is a biochemical.</p>Formula:C19H34N8O8Color and Shape:SolidMolecular weight:502.52SP-471
<p>SP-471 is a potent inhibitor of dengue virus (DENV) protease (IC50: 18 μM) and inhibits the inter- and intramolecular protease processes of DENV.</p>Formula:C33H26BrN5Color and Shape:SolidMolecular weight:572.5MsbA-IN-5
<p>MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.</p>Formula:C23H19Cl2N5OColor and Shape:SolidMolecular weight:452.34AG-7404
CAS:<p>AG-7404: strong protease inhibitor, fights poliovirus, EC50 0.080-0.674 μM, effective on V-073-resistant strains.</p>Formula:C26H29N5O7Color and Shape:SolidMolecular weight:523.54Palmitanilide
CAS:<p>Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.</p>Formula:C22H37NOColor and Shape:SolidMolecular weight:331.535Antiviral agent 15
<p>Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).</p>Formula:C27H24FN5OColor and Shape:SolidMolecular weight:453.51NS2B/NS3-IN-4
CAS:<p>Compound 34e inhibits DENV2/ZIKV proteases; IC50: 0.69 µM (DENV2), 1.04 µM (ZIKV).</p>Formula:C15H11NO4Color and Shape:SolidMolecular weight:269.25Ep vinyl quinidine
CAS:<p>3-Epiquinine is a Quinidine stereoisomer, used in malaria, antiarrhythmic, inhibits P450db, and blocks K+ channels, IC50: 19.9 μM.</p>Formula:C20H24N2O2Color and Shape:SolidMolecular weight:324.42Ciluprevir
CAS:<p>Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.</p>Formula:C40H50N6O8SPurity:98%Color and Shape:SolidMolecular weight:774.93SARS-CoV-2 PLpro-IN-1
CAS:<p>SARS-CoV-2 PLpro-IN-1 (Compound 85) is a non-covalent competitive inhibitor of SARS-CoV-2 PLpro with an IC50 value of 15.06 μM and a Ki value of 22.93 μM. It inhibits the proliferation of Vero cells, exhibiting an IC50 of 7.47 μM.</p>Formula:C18H19N5OColor and Shape:SolidMolecular weight:321.376CRS-3123
CAS:<p>CRS-3123, a methionyl-tRNA synthetase inhibitor, is used potentially for the treatment of enteric infections.</p>Formula:C19H19Br2N3O2SPurity:98%Color and Shape:SolidMolecular weight:513.25Antiviral agent 67
CAS:<p>Antiviralagent 67 (compound PC6) is an inhibitor of DENVNS5 (RNA-dependent RNA polymerase) with a Ki value of 1.12 nM.</p>Formula:C19H19N3OColor and Shape:SolidMolecular weight:305.374UMPK ligand 1
CAS:<p>UMPK ligand 1 (ZINC07785412) serves as a ligand for uridine monophosphate kinase (UMPK).</p>Formula:C15H22N4O5SColor and Shape:SolidMolecular weight:370.424Antibacterial agent 99
CAS:<p>Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.</p>Formula:C27H27BrN2Color and Shape:SolidMolecular weight:459.42FGI-106
CAS:<p>FGI-106 combats Ebola, Rift Valley, Dengue Fever, HCV, and HIV-1; EC50s range from 100-900 nM.</p>Formula:C28H38N6Purity:98%Color and Shape:SolidMolecular weight:458.64HIV-IN-3
<p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>Formula:C21H32ClN7O3Color and Shape:SolidMolecular weight:465.98Flutimide
CAS:<p>Flutimide: Endonuclease inhibitor, IC50 = 3μM, for research on acute respiratory diseases like influenza.</p>Formula:C12H18N2O3Color and Shape:SolidMolecular weight:238.28(S)-ZG197
<p>(S)-ZG197 is a compound that acts as a highly selective activator of the Staphylococcus aureus Caseinolytic Protease P (Sa ClpP), demonstrating efficacy at a</p>Formula:C28H35F3N4O3Color and Shape:SolidMolecular weight:532.6SARS-CoV-2-IN-6
<p>SARS-CoV-2-IN-6 is an inhibitor of SARS-CoV-2 3CLpro with the IC 50 value of 73 nM.</p>Formula:C17H13ClN2O2Color and Shape:SolidMolecular weight:312.75Methyl 3-oxodecanoate
CAS:<p>Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.</p>Formula:C11H20O3Color and Shape:SolidMolecular weight:200.275epi-D-Captopril
CAS:<p>epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and functions as an inhibitor of metallo-beta-lactamases (MBLs). The IC50 values of epi-D-Captopril for NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. This compound holds potential for research in MBLs-related antibiotic-resistant infections.</p>Formula:C9H15NO3SColor and Shape:SolidMolecular weight:217.285Mt KARI-IN-1
<p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>Formula:C14H11N5O4S2Color and Shape:SolidMolecular weight:377.4C-467929
CAS:<p>C-467929 is an inhibitor of the Nsp15 endoribonuclease, exhibiting an IC50 value of 8 μM. This compound binds to the SARS-CoVNsp15 protein and is applicable for infection research.</p>Formula:C29H20N4O10Color and Shape:SolidMolecular weight:584.494'-Ethynyl-2'-deoxyadenosine
CAS:<p>4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).</p>Formula:C12H13N5O3Purity:98%Color and Shape:SolidMolecular weight:275.26(R)-CSN5i-3
CAS:<p>(R)-CSN5i-3 is CSN5i-3 of the R configuration.</p>Formula:C28H29F2N5O2Purity:99.76% - 99.97%Color and Shape:SolidMolecular weight:505.56L 689065
CAS:<p>L 689065 is a 5-lipoxygenase inhibitor.</p>Formula:C35H33ClN2O3SPurity:98%Color and Shape:SolidMolecular weight:597.17DNA polymerase-IN-6
CAS:<p>DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, with EC50 values of 0.33 µM for HCMV, 1.9 µM for HSV-1, 0.76 µM for HSV-2, and 0.066 µM for EBV.</p>Formula:C26H28ClFN8O4Color and Shape:SolidMolecular weight:571.003ACHN-975 TFA
CAS:<p>ACHN-975 TFA is a selective LpxC inhibitor with a subnanomolar inhibitory. It is against a wide range of gram-negative bacterias with low MIC values (≤1 μg/mL).</p>Formula:C22H24F3N3O6Purity:98%Color and Shape:SolidMolecular weight:483.4377Metesind Glucuronate
CAS:<p>Metesind Glucuronate is an antineoplastic. It also is a specific thymidylate synthase inhibitor.</p>Formula:C29H34N4O10SColor and Shape:SolidMolecular weight:630.67WQ3810
CAS:<p>WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.</p>Formula:C22H22F3N5O3Purity:98%Color and Shape:SolidMolecular weight:461.44Kinamycin B
CAS:<p>Kinamycin B is an antibacterial agent with anticancer activity.</p>Formula:C20H16N2O8Purity:98%Color and Shape:SolidMolecular weight:412.35Antibacterial agent 79
<p>Antibacterial agent 79 is an antibacterial agent.</p>Formula:C18H27N3O2S3Color and Shape:SolidMolecular weight:413.62Ibafloxacine
CAS:<p>Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect against</p>Formula:C15H14FNO3Purity:97.67%Color and Shape:SolidMolecular weight:275.27YKL-04-085
CAS:<p>YKL-04-085 inhibits viral translation effectively, with strong antiviral action at much lower doses than those affecting host-cell growth.</p>Formula:C30H29N5O2Color and Shape:SolidMolecular weight:491.6Dencatistat
CAS:<p>Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.</p>Formula:C24H27N7O5SPurity:98.85%Color and Shape:SolidMolecular weight:525.58NBTIs-IN-4
<p>NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.</p>Formula:C22H24FN5O5SColor and Shape:SolidMolecular weight:489.52MsbA-IN-1
<p>MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.</p>Formula:C23H18Cl2FNO3Color and Shape:SolidMolecular weight:446.3Antifungal agent 40
<p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>Formula:C22H20Cl2N4SeColor and Shape:SolidMolecular weight:490.29Chitin synthase inhibitor 11
<p>Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.</p>Formula:C24H24N4O8Color and Shape:SolidMolecular weight:496.47PRRSV-IN-1
CAS:<p>PRRSV-IN-1 (Compound 4s) acts as an inhibitor of the nsp4 protease of PRRSV. It has an EC50 value of 0.45 μM against PRRSV, binds to the nsp4 protease with a Kd of 29.24 pM, and exhibits an IC50 value of 80.36 pM for nsp4 protease inhibition. PRRSV-IN-1 is applicable in antiviral infection research.</p>Formula:C19H18BrNO3Color and Shape:SolidMolecular weight:388.255WR-27653
CAS:<p>WR-27653 (RC-12), a derivative of Catechol, demonstrates significant activity against hypnozoites in the Plasmodium cynomolgi-Rhesus monkey (Macaca mulatta) model, which is considered the gold standard. Additionally, WR-27653 exhibits antimalarial properties.</p>Formula:C20H36BrN3O2Color and Shape:SolidMolecular weight:430.423NBD-10007
CAS:<p>NBD-10007 is an inhibitor of HIV-1 entry.</p>Formula:C20H25ClN4O3SPurity:98%Color and Shape:SolidMolecular weight:436.96L 702007
CAS:<p>L 702007 is an inhibitor of HIV-1 reverse transcriptase.</p>Formula:C18H25N3O2Purity:98%Color and Shape:SolidMolecular weight:315.41HBV-IN-20
<p>HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).</p>Color and Shape:SolidGanaplacide hydrochloride
CAS:<p>Ganaplacide hydrochloride (KAF156 HCl) is an orally administered imidazopyrimidine antimalarial agent that inhibits Plasmodium PI4K activity.</p>Formula:C22H24ClF2N5OPurity:93.97%Color and Shape:SoildMolecular weight:447.91Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Formula:C21H19F2N7O3S2Color and Shape:SolidMolecular weight:519.55MTH1 activator-1
CAS:<p>MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.</p>Formula:C29H23F3N4O2Color and Shape:SolidMolecular weight:516.514Antibacterial agent 82
<p>Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].</p>Formula:C22H18N2O2Color and Shape:SolidMolecular weight:342.39Eravacycline
CAS:<p>Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.</p>Formula:C27H31FN4O8Purity:97.46%Color and Shape:SolidMolecular weight:558.56G247
<p>G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.</p>Formula:C24H19Cl2FO3Color and Shape:SolidMolecular weight:445.31GS-9822
CAS:<p>GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.</p>Formula:C36H39ClN4O4SColor and Shape:SolidMolecular weight:659.24PKZ18
CAS:<p>PKZ18 is an antibiotic that inhibits bacterial growth with a MIC value of 32-64 μg/mL against most Gram-positive bacteria. It suppresses the in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria, directly reducing T-box transcription readthrough of associated genes. It prevents codon-anticodon pairing necessary for tRNA binding and is less likely to induce resistance.</p>Formula:C22H26N2O3SColor and Shape:SolidMolecular weight:398.5183HKT-IN-1
CAS:<p>3HKT-IN-1 (Compound 17122279) is an inhibitor of Anopheles gambiae 3-hydroxykynurenine transaminase (3HKT) and is utilized in malaria research.</p>Formula:C12H11BrN2O3Color and Shape:SolidMolecular weight:311.131MsbA-IN-3
<p>MsbA-IN-3 is a potent and highly selective MsbA inhibitor (IC50: 2 nM). MsbA-IN-3 inhibits Escherichia coli activity (MIC: 35 μM).</p>Formula:C24H22Cl2N2O4SColor and Shape:SolidMolecular weight:505.41Tuberculosis inhibitor 4
<p>TB inhibitor 4, a spirothiazolidinone from mandelic acid, blocks 98% of M. tuberculosis H37Rv under 6 μg/mL.</p>Formula:C23H26N2O3SColor and Shape:SolidMolecular weight:410.533-Deazaguanosine
CAS:<p>3-Deazaguanosine (C3Guo) exhibits potent antiviral activity against SARS-CoV-2 with an EC50 of 1.14 μM and a CC50 greater than 200 μM in Vero E6 cells. It has the potential to prevent COVID-19.</p>Formula:C11H14N4O5Color and Shape:SolidMolecular weight:282.25Antibacterial agent 63
CAS:<p>Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to a</p>Formula:C35H43N9O14S2Color and Shape:SolidMolecular weight:877.9ZK-806450
CAS:<p>ZK-806450 is a compound with antiviral properties. It exhibits high binding potential to the allosteric site of the SARS-CoV-2 3CL protease and is capable of specific and stable interaction with the GAG site of the dengue virus envelope protein.</p>Formula:C31H31N5OColor and Shape:SolidMolecular weight:489.611Cyclophilin inhibitor 1
CAS:<p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>Formula:C31H39N5O7Purity:98%Color and Shape:SolidMolecular weight:593.67PLP_Snyder530
<p>PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.</p>Formula:C24H24N2O2Color and Shape:SolidMolecular weight:372.46Antibacterial agent 90
<p>Antibacterial agent 90 (6n), a pleuromutilin derivative, targets Gram-positive pathogens and Mycoplasma pneumoniae.</p>Formula:C30H42N2O6Color and Shape:SolidMolecular weight:526.66Squalamine lactate
CAS:<p>Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.</p>Formula:C37H71N3O8SPurity:98%Color and Shape:SolidMolecular weight:718.04Anti-MRSA agent 6
<p>Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].</p>Formula:C16H11F2N3Color and Shape:SolidMolecular weight:283.28trans-Clopenthixol
CAS:<p>Trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic without any sedative properties. It can be used in vitro to inhibit Pseudomonas aeruginosa and Plasmodium falciparum.</p>Formula:C22H25ClN2OSColor and Shape:SolidMolecular weight:400.965Saphenamycin
CAS:<p>Saphenamycin is an antibiotic from a strain of Streptomyces.</p>Formula:C23H18N2O5Purity:98%Color and Shape:SolidMolecular weight:402.40RSV-IN-5
CAS:<p>RSV-IN-5: Dual inhibitor for RSV fusion proteins, effective on wild-type A2 and D486N mutant with EC50s of 2.0 nM & 8.1 nM. Potent anti-RSV.</p>Formula:C28H37N7O2Color and Shape:SolidMolecular weight:503.642-CEES
CAS:<p>2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.</p>Formula:C4H9ClSColor and Shape:SolidMolecular weight:124.632LolCDE-IN-2
CAS:<p>LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].</p>Formula:C22H17N5OPurity:98%Color and Shape:SolidMolecular weight:367.40Anti-MRSA agent 27
CAS:<p>Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.</p>Formula:C15H10F3N3OSColor and Shape:SolidMolecular weight:337.32A25822B
CAS:<p>A25822B is an antifungal agent.</p>Formula:C28H45NOPurity:98%Color and Shape:SolidMolecular weight:411.66PCNA-IN-1
CAS:<p>PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.</p>Formula:C19H18I3NO3Color and Shape:SolidMolecular weight:689.065β-Glucuronidase-IN-2
<p>β-Glucuronidase-IN-2 is a potent inhibitor of E.</p>Formula:C21H17Cl3O7Color and Shape:SolidMolecular weight:487.71Doxazosin impurity 12
CAS:<p>Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.</p>Formula:C10H6O5SColor and Shape:SolidMolecular weight:238.217Anti-infective agent 10
CAS:<p>Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.</p>Formula:C26H25N3O7SColor and Shape:SolidMolecular weight:523.56Antibacterial agent 66
<p>Compound 6q, a trifluoromethylpyridine oxadiazole, targets Xanthomonas oryzae with EC50 of 7.2 μg/mL.</p>Formula:C17H10ClF6N3O2SColor and Shape:SolidMolecular weight:469.79(Rac)-Plevitrexed
CAS:<p>(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).</p>Formula:C26H25FN8O4Purity:98%Color and Shape:SolidMolecular weight:532.53PFK-IN-1
CAS:<p>PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.</p>Formula:C18H15Cl2N3O4SColor and Shape:SolidMolecular weight:440.3Saussureamine C
CAS:<p>Saussureamine C is an inhibitor of H274Y and N294S mutants.</p>Formula:C19H26N2O5Color and Shape:SolidMolecular weight:362.42HIV-1 inhibitor-13
<p>HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).</p>Formula:C30H32N6O3Color and Shape:SolidMolecular weight:524.61BRL-42715
CAS:<p>BRL-42715 is an effective inhibitor of bacterial beta-lactamases.</p>Formula:C10H7N4NaO3SPurity:98%Color and Shape:SolidMolecular weight:286.24ZIKV-IN-4
<p>ZIKV-IN-4 is a low cytotoxic, acid-stable anti-ZIKV agent with an EC50 value of 3.49 μM. ZIKV-IN-4 exhibited potent inhibition of ZIKV NS5 MTase.</p>Formula:C33H37NO4Color and Shape:SolidMolecular weight:511.65DHX9-IN-19
CAS:<p>DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.</p>Formula:C20H21ClN4O4S2Color and Shape:SolidMolecular weight:480.988MAY0132
CAS:<p>MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.</p>Formula:C16H15ClF3NColor and Shape:SolidMolecular weight:313.745NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Formula:C14H9IN2O3SColor and Shape:SolidMolecular weight:412.2MsbA-IN-2
<p>MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).</p>Formula:C23H19Cl2NO3Color and Shape:SolidMolecular weight:428.31ABT-072
CAS:<p>ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.</p>Formula:C24H27N3O5SPurity:98%Color and Shape:SolidMolecular weight:469.55Neuraminidase-IN-4
<p>Neuraminidase-IN-4 inhibits neuraminidase (EC50: 1.59 μM) and has strong anti-H5N1 activity.</p>Formula:C21H20N2O6SColor and Shape:SolidMolecular weight:428.461,5-Dideoxy-1,5-imino-D-mannitol
CAS:<p>1,5-Dideoxy-1,5-imino-D-mannitol is an antibiotic with antibacterial properties.</p>Formula:C6H13NO4Color and Shape:SolidMolecular weight:163.172Menoctone
CAS:<p>Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.</p>Formula:C24H32O3Color and Shape:SolidMolecular weight:368.51Meclocycline
CAS:<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Formula:C22H21ClN2O8Color and Shape:SolidMolecular weight:476.86SARS-CoV-2 Mpro-IN-31
CAS:<p>SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 of 11 nM. Additionally, this compound effectively inhibits the enzymatic activity of the cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively.</p>Formula:C31H34Cl2N4O7Color and Shape:SolidMolecular weight:645.53Tenellin
CAS:<p>Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.</p>Formula:C21H23NO5Color and Shape:SolidMolecular weight:369.41UNC0638 hydrate
CAS:<p>UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1/2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.</p>Formula:C30H49N5O3Color and Shape:SolidMolecular weight:527.74SARS-CoV-2-IN-102
CAS:<p>SARS-CoV-2-IN-102 (example 58) is an inhibitor of the SARS-CoV papain-like protease (SARS-CoVPLpro), demonstrating an IC50 of less than 100 nM.</p>Formula:C29H34F2N6O2Color and Shape:SolidMolecular weight:536.62Antifungal agent 113
CAS:<p>Antifungalagent 113 (compound 9a) serves as an effective antifungal and antibacterial agent. It exhibits strong inhibitory activity against both S. aureus and methicillin-resistant S. aureus.</p>Formula:C23H20O5Color and Shape:SolidMolecular weight:376.40HRSV/HMPV-IN-1
CAS:<p>HRSV/HMPV-IN-1 (compound 3) is an inhibitor targeting HRSV/HMPV, exhibiting EC50 values of < 0.2 μM against human RSV-A and < 0.5 μM for human MPV A2 TN/94-49. This compound is utilized in the study of bronchiolitis and pneumonia.</p>Formula:C34H31ClF2N4O5SColor and Shape:SolidMolecular weight:681.15MED6-189
CAS:<p>MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.</p>Formula:C17H26N2OColor and Shape:SolidMolecular weight:274.40ZINC4497834
CAS:<p>ZINC4497834 is an inhibitor of the main protease Mpro of SARS-CoV-2. It is utilized in research targeting the treatment of COVID-19.</p>Formula:C18H19N5O3SColor and Shape:SolidMolecular weight:385.44PLpro-IN-7
CAS:<p>PLpro-IN-7 (compound 83) is a novel papain-like protease (PLpro) inhibitor with an IC50 of 3 nM.</p>Formula:C30H34ClN7OColor and Shape:SolidMolecular weight:544.09Plevitrexed
CAS:<p>Plevitrexed, an oral TS inhibitor (Ki: 0.44 nM), targets α-folate receptor & reduced folate carrier, treats gastric cancer.</p>Formula:C26H25FN8O4Purity:98%Color and Shape:SolidMolecular weight:532.53Penethamate hydriodide
CAS:<p>Penethamate hydriodide is a diethylaminoethyl ester prodrug of penicillin, utilized via intramuscular injection to treat mastitis in cattle.</p>Formula:C22H32IN3O4SColor and Shape:SolidMolecular weight:561.477TKB272
CAS:<p>TKB272 is an orally active antiviral agent that selectively targets the main protease (Mpro) of SARS-CoV-2, effectively inhibiting the infection and replication of various strains, including Omicron variants (such as XBB.1.5 and EG.5.1). It exhibits an enzyme inhibitory activity with an IC50 of 0.7 µM against SARS-CoV-2WK-521 Mpro and shows potent antiviral activity at the cellular level with an EC50 as low as 2.6 nM in HeLahACE2-TMPRSS2 cells against the BQ.1.1 strain. TKB272 also has a CC50 of 98 µM, indicating low cytotoxicity. Furthermore, it demonstrates a significant suppression of SARS-CoV-2XBB.1.5 replication in the B6.Cg-Tg(K18-hACE2)2-Prlmn/J transgenic mouse model, suggesting potential use in the research of SARS-CoV-2 infections.</p>Formula:C30H35F4N5O5SColor and Shape:SolidMolecular weight:653.688RAD51-IN-8
<p>RAD51-IN-8 inhibits RAD51-BRCA2 interaction and H4A4 with EC50 of 19 μM; a micromolar PPI inhibitor.</p>Formula:C16H14Cl2FN3O2Color and Shape:SolidMolecular weight:370.21FNC-TP trisodium
<p>FNC-TP trisodium, active intracellular FNC form, inhibits NRTI, fights HIV, HBV, and HCV.</p>Formula:C9H11FN6Na3O13P3Color and Shape:SolidMolecular weight:592.11Succinate dehydrogenase-IN-8
CAS:<p>Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).</p>Formula:C22H19Cl2F2N5O2Color and Shape:SolidMolecular weight:494.32Antifungal agent 16
<p>Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.</p>Formula:C27H21N5O2SColor and Shape:SolidMolecular weight:479.55
