Microbiology/Virology
Microbiology and virology inhibitors are compounds that target microorganisms, including bacteria, viruses, and fungi, disrupting their growth, replication, or survival. These inhibitors are essential for studying microbial pathogenesis, understanding resistance mechanisms, and developing new antimicrobial and antiviral therapies. Inhibitors in this category are used to combat infectious diseases, explore microbial ecology, and investigate host-pathogen interactions. At CymitQuimica, we provide a broad selection of high-quality microbiology and virology inhibitors to support your research in infectious diseases, microbiology, and virology.
Subcategories of "Microbiology/Virology"
- Antibacterial(2,949 products)
- Antibiotic(918 products)
- Antifection(23 products)
- DHFR(32 products)
- DNA/RNA Synthesis(706 products)
- HBV(176 products)
- HIV Protease(447 products)
- HSV(91 products)
- Integrase(2 products)
- Ribosome(13 products)
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Found 5832 products of "Microbiology/Virology"
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UNC0638 hydrate
CAS:<p>UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1/2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.</p>Formula:C30H49N5O3Color and Shape:SolidMolecular weight:527.74HT1171
CAS:<p>HT1171 is a potent and selective inhibitor of the Mycobacterium tuberculosis proteasome. It exhibits strong antitubercular activity against Mycobacterium tuberculosis H37Rv, with a MIC90 of 2 μg/mL and MIC of 4 μg/mL. At a concentration of 100 μM, HT1171 shows an inhibition rate of 53.8% against normal human liver cells (L02). HT1171 is applicable in antituberculosis drug research.</p>Formula:C7H4N2O4S2Color and Shape:SolidMolecular weight:244.248Antitubercular agent-11
<p>Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].</p>Formula:C16H15N3O4Color and Shape:SolidMolecular weight:313.31Menoctone
CAS:<p>Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.</p>Formula:C24H32O3Color and Shape:SolidMolecular weight:368.51Alpibectir
CAS:<p>Alpibectir has antibacterial activity [1].</p>Formula:C12H14F6N2O2Color and Shape:SolidMolecular weight:332.24Antitrypanosomal agent 5
<p>Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).</p>Formula:C30H30N6O4SColor and Shape:SolidMolecular weight:570.66Anti-Trypanosoma cruzi agent-2
<p>Compd 3b: anti-trypanosomal, IC50 0.51 μM (NINOA), 3.06 μM (INC-5), also combats T. gondii.</p>Formula:C17H10ClNO5Color and Shape:SolidMolecular weight:343.72Antibacterial agent 172
CAS:<p>Antibacterial Agent 172 (Compound 6a), a <i>Clostridioides difficile (Cd) SpoVD inhibitor with an IC50 value of 89 nM, effectively inhibits the sporulation of Clostridioides difficile. It is useful for research on bacterial infections [1].</p>Formula:C21H21N9O5S2Color and Shape:SolidMolecular weight:543.5820S Proteasome-IN-4
CAS:<p>20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.</p>Formula:C20H18ClF2N3O3Color and Shape:SolidMolecular weight:421.832-CEES
CAS:<p>2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.</p>Formula:C4H9ClSColor and Shape:SolidMolecular weight:124.632Antifungal agent 125
CAS:<p>Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.</p>Formula:C13H10BrNO4SColor and Shape:SolidMolecular weight:356.192CDA-IN-2
CAS:<p>CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.</p>Formula:C17H16N2O7Color and Shape:SolidMolecular weight:360.318SP-471
<p>SP-471 is a potent inhibitor of dengue virus (DENV) protease (IC50: 18 μM) and inhibits the inter- and intramolecular protease processes of DENV.</p>Formula:C33H26BrN5Color and Shape:SolidMolecular weight:572.5RmlA-IN-2
<p>RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).</p>Formula:C22H26BrN5O4SColor and Shape:SolidMolecular weight:536.44HBV-IN-31
CAS:<p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>Formula:C23H18ClNO6Color and Shape:SolidMolecular weight:439.85Antitubercular agent-16
<p>Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.</p>Formula:C21H27N3SColor and Shape:SolidMolecular weight:353.52MsbA-IN-5
<p>MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.</p>Formula:C23H19Cl2N5OColor and Shape:SolidMolecular weight:452.34NIP-22c
CAS:<p>NIP-22c, a novel inhibitor of coronavirus 3CL pro, exhibits antiviral activity [1]. The compound's EC50 values are 4.6 μM for Verona, 1.1 μM for Calu3, 0.1 μM for Caco2, and 0.6 μM for HBTEC-ALI.</p>Formula:C32H39N5O6Color and Shape:SolidMolecular weight:589.68AG-7404
CAS:<p>AG-7404: strong protease inhibitor, fights poliovirus, EC50 0.080-0.674 μM, effective on V-073-resistant strains.</p>Formula:C26H29N5O7Color and Shape:SolidMolecular weight:523.54BDM91288
CAS:<p>BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].</p>Formula:C17H22ClN5Color and Shape:SolidMolecular weight:331.84Antitubercular agent-15
<p>Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.</p>Formula:C21H29FN2Color and Shape:SolidMolecular weight:328.47LpxC-IN-10
CAS:<p>LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.</p>Formula:C30H31N5O3Color and Shape:SolidMolecular weight:509.6MA220607
CAS:<p>MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].</p>Formula:C34H38INColor and Shape:SolidMolecular weight:587.58Beclabuvir
CAS:<p>Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.</p>Formula:C36H45N5O5SPurity:99.87% - 99.93%Color and Shape:SolidMolecular weight:659.84Pks13-TE inhibitor 4
CAS:<p>Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.</p>Formula:C26H25N5O6Molecular weight:503.51GR 122222X
CAS:<p>GR 122222X is an inhibitor of topoisomerase II.</p>Formula:C26H35N5O11SPurity:98%Color and Shape:SolidMolecular weight:625.65Amicoumacin A
CAS:<p>Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.</p>Formula:C20H29N3O7Purity:98%Color and Shape:SolidMolecular weight:423.46N-Cbz-L-Cysteine
CAS:<p>N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].</p>Formula:C11H13NO4SColor and Shape:SolidMolecular weight:255.29Neuraminidase-IN-18
CAS:<p>Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].</p>Formula:C22H18FN3O3SColor and Shape:SolidMolecular weight:423.46FGI-106
CAS:<p>FGI-106 combats Ebola, Rift Valley, Dengue Fever, HCV, and HIV-1; EC50s range from 100-900 nM.</p>Formula:C28H38N6Purity:98%Color and Shape:SolidMolecular weight:458.64HIV-IN-3
<p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>Formula:C21H32ClN7O3Color and Shape:SolidMolecular weight:465.98DIDS
CAS:<p>DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.</p>Formula:C16H10N2O6S4Purity:98%Color and Shape:SolidMolecular weight:454.52CYP2C19-IN-1
<p>CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.</p>Formula:C26H26N2O6SColor and Shape:SolidMolecular weight:494.56Antibacterial agent 118
<p>Antibacterial agent 118, potent against various mycobacteria, has MIC values ranging from 10.2 to 163.0 μM. Useful in TB research.</p>Formula:C19H21N5O2SColor and Shape:SolidMolecular weight:383.47TCMDC-136230
<p>TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.</p>Formula:C24H34N4O2SColor and Shape:SolidMolecular weight:442.62WRN inhibitor 7
CAS:<p>WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].</p>Formula:C27H23N3O6Color and Shape:SolidMolecular weight:485.49Chitinase-IN-4
<p>Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.</p>Formula:C21H24ClN7Color and Shape:SolidMolecular weight:409.925-Methylcytosine hydrochloride
CAS:<p>5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.</p>Formula:C5H8ClN3OColor and Shape:SolidMolecular weight:161.59Squalamine lactate
CAS:<p>Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.</p>Formula:C37H71N3O8SPurity:98%Color and Shape:SolidMolecular weight:718.048-Hydroxyerythromycin A
CAS:<p>8-Hydroxyerythromycin A is a semi-synthetic antibiotic with antibacterial activity.</p>Formula:C37H67NO14Color and Shape:SolidMolecular weight:749.926BMT-052
CAS:<p>BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).</p>Formula:C30H17D9F4N6O5Purity:98%Color and Shape:SolidMolecular weight:635.61Antibacterial agent 75
<p>Antibacterial agent 75 re-sensitizes VRSA to vancomycin.</p>Formula:C22H28N6OColor and Shape:SolidMolecular weight:392.5YKL-04-085
CAS:<p>YKL-04-085 inhibits viral translation effectively, with strong antiviral action at much lower doses than those affecting host-cell growth.</p>Formula:C30H29N5O2Color and Shape:SolidMolecular weight:491.6NBTIs-IN-4
<p>NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.</p>Formula:C22H24FN5O5SColor and Shape:SolidMolecular weight:489.52HldA/E-IN-1
CAS:<p>HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, exhibiting IC50 values of 17.2 μM and 67.8 μM, respectively. This compound is utilized in research on antibacterial infections.</p>Formula:C8H17FO13P2Color and Shape:SolidMolecular weight:402.16Pol I-IN-1
<p>Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition</p>Formula:C23H22N4O2Color and Shape:SolidMolecular weight:386.45Cefclidin
CAS:<p>Cefclidin (Cefclidine) is a cephalosporin compound.</p>Formula:C21H26N8O6S2Color and Shape:SolidMolecular weight:550.611VNI
CAS:<p>VNI is an effective inhibitor of CYP51. It suppresses sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity.</p>Formula:C26H19Cl2N5O2Color and Shape:SolidMolecular weight:504.37Carbonic anhydrase inhibitor 28
<p>Carbonic anhydrase inhibitor28 (Compound 11) serves as an inhibitor for the Pseudomonas aeruginosa carbonic anhydrase. It exhibits antibacterial activity, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 0.5 and 1 μg/mL, respectively, against P. aeruginosa. Carbonic anhydrase inhibitor28 is utilized in research focused on anti-infection applications.</p>Formula:C24H24FN5O7SColor and Shape:SolidMolecular weight:545.54Antimalarial agent 44
<p>Antimalarial agent 44 (Compound 3) is an antiparasitic agent effective against malaria. It exhibits good permeability in MDCK-MDR1 cell monolayers and has a high clearance rate in mouse liver microsomes.</p>Formula:C37H37N5O7Color and Shape:SolidMolecular weight:663.72
