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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5400 products of "Neuroscience"

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  • CymitQuimica logo
    Targetmol
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    CaMKIIα-IN-1

    <p>CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.</p>
    Formula:C14H11ClO4
    Color and Shape:Solid
    Molecular weight:278.69

    Ref: TM-T60515

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    Monoamine Oxidase B inhibitor 2

    <p>MAO-B inhibitor 2: potent, reversible, oral, selective (IC50=1.33 nM), BBB-penetrant, with anti-oxidant and anti-inflammatory effects for Parkinson's study.</p>
    Formula:C19H19FO3
    Color and Shape:Solid
    Molecular weight:314.35

    Ref: TM-T60806

  • Mesulergine hydrochloride
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    Mesulergine hydrochloride

    CAS:
    <p>5-HT2A and 2C receptor antagonist</p>
    Formula:C18H27ClN4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:398.95

    Ref: TM-T22970

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    AChE-IN-22

    <p>AChE-IN-22 (10q) selectively inhibits AChE (IC50: 0.88 μM), less on BuChE (IC50: 10 μM), targets CAS and PAS, useful in Alzheimer's research.</p>
    Formula:C21H20N4O5S
    Color and Shape:Solid
    Molecular weight:440.47

    Ref: TM-T62541

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    5-HT1A antagonist 1

    <p>Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.</p>
    Formula:C23H29ClN6O2
    Color and Shape:Solid
    Molecular weight:456.97

    Ref: TM-T62843

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    AChE/BACE1/GSK3β-IN-1

    <p>AChE/BACE1/GSK3β-IN-1 is an orally active, blood-brain barrier-transparent, moderately bioavailable triple inhibitor of AChE/BACE1/GSK3β.</p>
    Formula:C26H27FN2O4
    Color and Shape:Solid
    Molecular weight:450.5

    Ref: TM-T62719

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    K203

    <p>K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.</p>
    Formula:C16H18Br2N4O2
    Color and Shape:Solid
    Molecular weight:458.15

    Ref: TM-T62857

  • SGE-516
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    SGE-516

    CAS:
    <p>SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.</p>
    Formula:C23H35N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:385.54

    Ref: TM-T28766

  • γ-Secretase modulator 11 hydrochloride
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    γ-Secretase modulator 11 hydrochloride

    CAS:
    <p>γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM).</p>
    Formula:C28H23ClF2N4O2
    Color and Shape:Solid
    Molecular weight:520.96

    Ref: TM-T63638

  • LB-102
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    LB-102

    CAS:
    <p>LB-102 is an orally active inhibitor of dopamine D2, D3, and serotonin 5-HT7 receptors, utilized in the study of schizophrenia and other psychiatric disorders.</p>
    Formula:C18H29N3O4S
    Color and Shape:Solid
    Molecular weight:383.51

    Ref: TM-T200914

  • DL-AP5 lithium
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    DL-AP5 lithium

    CAS:
    <p>DL-AP5 (2-APV) lithium is a competitive antagonist of the NMDA (N-Methyl-D-aspartate) receptor. It exhibits notable analgesic activity and specifically blocks channels in the rabbit retina.</p>
    Formula:C5H11LiNO5P
    Color and Shape:Solid
    Molecular weight:203.06

    Ref: TM-T201724

  • SB 243213 dihydrochloride
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    SB 243213 dihydrochloride

    CAS:
    <p>SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for</p>
    Formula:C22H21Cl2F3N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:501.33

    Ref: TM-T12859L

  • Remlifanserin
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    Remlifanserin

    CAS:
    <p>Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).</p>
    Formula:C24H29F2N3O2
    Color and Shape:Solid
    Molecular weight:429.50

    Ref: TM-T201055

  • Tuclazepam
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    Tuclazepam

    CAS:
    <p>Tuclazepam (KC 1956) is a derivative of the benzodiazepine class of drugs, exhibiting anti-anxiety and sedative properties.</p>
    Formula:C17H16Cl2N2O
    Color and Shape:Solid
    Molecular weight:335.23

    Ref: TM-T201570

  • hMAO-B-IN-10
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    hMAO-B-IN-10

    <p>hMAO-B-IN-10 (compound 7) is an inhibitor of MAO-A/B with IC50 values of 424.1 nM and 177.9 nM, respectively. It has demonstrated neuroprotective effects in the MPTP-induced mouse model of Parkinson's Disease (PD).</p>
    Formula:C16H12N4O4
    Color and Shape:Solid
    Molecular weight:324.29

    Ref: TM-T201531

  • BACE1-IN-5
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    BACE1-IN-5

    CAS:
    <p>BACE1-IN-5 inhibits BACE1 (IC50: 9.1 nM) &amp; Aβ production (IC50: 0.82 nM), enhances hERG inhibition &amp; P-gp efflux.</p>
    Formula:C18H16F5N5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:461.41

    Ref: TM-T10453

  • Elzasonan hydrochloride
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    Elzasonan hydrochloride

    CAS:
    <p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>
    Formula:C22H24Cl3N3OS
    Color and Shape:Solid
    Molecular weight:484.87

    Ref: TM-T201763

  • PXS-4787 hydrochloride
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    PXS-4787 hydrochloride

    CAS:
    <p>PXS-4787 hydrochloride is a specific and potent pan-lysyl oxidase inhibitor that effectively eliminates the activity of lysyl oxidase. It exhibits varying IC50 values against different forms of the enzyme, including 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), and 0.2 μM (rh LOXL4). In addition, PXS-4787 hydrochloride reduces the deposition and cross-linking of collagen I secreted by human fibroblasts.</p>
    Formula:C10H13ClFNO2S
    Color and Shape:Solid
    Molecular weight:265.73

    Ref: TM-T201314

  • Rodatristat ethyl
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    Rodatristat ethyl

    CAS:
    <p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels &amp; lowering PAH at low doses.</p>
    Formula:C29H31ClF3N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:590.04

    Ref: TM-T16779

  • AChE/BChE-IN-10
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    AChE/BChE-IN-10

    CAS:
    <p>AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.</p>
    Formula:C26H30N2O2
    Purity:99.55% - 99.88%
    Color and Shape:Soild
    Molecular weight:402.53

    Ref: TM-T61969