Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(940 products)
- ACK(1 products)
- AChR(574 products)
- ATP Citrate Lyase(16 products)
- Adrenergic Receptor(2,939 products)
- BACE(36 products)
- Beta Amyloid(204 products)
- CaMK(68 products)
- Cyclooxygenase (COX) Inhibitors(562 products)
- Dopamine Receptor(407 products)
- GABA Receptor(336 products)
- Gamma-secretase(59 products)
- GluR(255 products)
- GlyT(24 products)
- Histamine Receptor(358 products)
- LRRK2(33 products)
- Melatonin Receptor(24 products)
- NMDAR(28 products)
- OX Receptor(40 products)
- Opioid Receptor(296 products)
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Found 5400 products of "Neuroscience"
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Calmodulin-Dependent Protein Kinase II 290-309 acetate
<p>Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).</p>Formula:C105H189N31O26SPurity:96.7%Color and Shape:SolidMolecular weight:2333.88Davunetide acetate
<p>Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS.</p>Formula:C38H64N10O14Purity:99.52% - 99.78%Color and Shape:SolidMolecular weight:884.97AC3-I, myristoylated
<p>Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).</p>Formula:C78H137N21O20Purity:98%Color and Shape:SolidMolecular weight:1689.05Hydroxytacrine maleate
CAS:<p>Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase inhibitor used in the study of Alzheimer's type dementia (SDAT).</p>Formula:C17H18N2O5Purity:98.84%Color and Shape:SolidMolecular weight:330.34MAO-B-IN-25
<p>MAO-B-IN-25 (compound 92) is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting inhibitory half-maximal inhibitory concentrations (IC50) of 240 nM</p>Formula:C16H13BrO3Purity:98%Color and Shape:SolidMolecular weight:333.18BSB
CAS:<p>BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.</p>Formula:C24H17BrO6Purity:95.53%Color and Shape:SolidMolecular weight:481.29COX-1/2-IN-5
<p>COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and</p>Formula:C21H22N2O5SPurity:98%Color and Shape:SolidMolecular weight:414.47Guvacine hydrobromide
CAS:<p>Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.</p>Formula:C6H10BrNO2Purity:98%Color and Shape:SolidMolecular weight:208.05Trontinemab
CAS:<p>Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).</p>Purity:96.77% - 99%Color and Shape:Liquid2,6-DMA hydrochloride
CAS:<p>2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.</p>Formula:C11H18ClNO2Color and Shape:SolidMolecular weight:231.72(Rac)-Sabcomeline
CAS:<p>(Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.</p>Formula:C10H15N3OPurity:99.14%Color and Shape:SolidMolecular weight:193.254-Iodoamphetamine hydrochloride
CAS:<p>4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.</p>Formula:C9H13ClINColor and Shape:SolidMolecular weight:297.565-(2-Aminopropyl)indole
CAS:<p>5-(2-Aminopropyl)indole is an orally active psychoactive substance that inhibits monoamine oxidase (MAO) and exhibits long-lasting stimulant effects.</p>Formula:C11H14N2Color and Shape:SolidMolecular weight:174.243-Hydroxy desalkylflurazepam
CAS:<p>3-Hydroxy desalkylflurazepam is a benzodiazepine compound with potential sedative and anxiolytic effects.</p>Formula:C15H10ClFN2O2Color and Shape:SolidMolecular weight:304.75-MeO-MET
CAS:<p>5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.</p>Formula:C14H20N2OColor and Shape:SolidMolecular weight:232.32Methyllycaconitine citrate
CAS:<p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>Formula:C43H58N2O17Purity:98.03% - 98.91%Color and Shape:SolidMolecular weight:874.9225N-NBOMe hydrochloride
CAS:<p>25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.</p>Formula:C18H23ClN2O5Color and Shape:SolidMolecular weight:382.84Desalkylgidazepam
CAS:<p>Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).</p>Formula:C15H11BrN2OColor and Shape:SolidMolecular weight:315.17Litoxetine HCl
<p>Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.</p>Formula:C16H20ClNOPurity:99.56% - 99.75%Color and Shape:SoildMolecular weight:277.79Desfesoterodine
CAS:<p>Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.</p>Formula:C22H31NO2Purity:99.77%Color and Shape:SolidMolecular weight:341.49BU 226 hydrochloride
CAS:<p>BU 226 hydrochloride demonstrates affinity for imidazoline (I) receptors, in particular the I2 binding site with a Ki of 1.4 nM.</p>Formula:C12H12ClN3Purity:99.67%Color and Shape:SolidMolecular weight:233.7MRS7925
<p>MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosis</p>Formula:C20H26IN5O3Purity:98%Color and Shape:SolidMolecular weight:511.365-HT6 agonist 1
<p>Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting platelet</p>Formula:C17H22Cl2N6SPurity:98%Color and Shape:SolidMolecular weight:413.37Aminoacetone hydrochloride
CAS:<p>Aminoacetone hydrochloride (1-Aminoacetone Hydrochloride) is an oxidative agent that induces loss of ferritin ferrireductase activity and iron uptake.</p>Formula:C3H8ClNOPurity:99.76%Color and Shape:SolidMolecular weight:109.56ZZL-7
CAS:<p>ZZL-7 is a rapid antidepressant targeting nNOS & SERT in DRN, crosses blood-brain barrier, with MDD research potential.</p>Formula:C11H20N2O4Purity:99.79%Color and Shape:SoildMolecular weight:244.294-Bromo-2,5-DMMA
CAS:<p>4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.</p>Formula:C12H18BrNO2Color and Shape:SolidMolecular weight:288.18MAO-B-IN-18
<p>MAO-B-IN-18 is a potent, selective inhibitor of MAO B, demonstrating IC50 values of 52 nM for hMAO B and 14 μM for hMAO A.</p>Formula:C25H22N4O5Purity:98%Color and Shape:SolidMolecular weight:458.47MAO-B-IN-3
<p>MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki</p>Formula:C24H25N3O2Purity:98%Color and Shape:SolidMolecular weight:387.47PZ-1922
<p>PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.</p>Purity:98%Color and Shape:Odour SolidDOPR hydrochloride
CAS:<p>DOPR hydrochloride is a psychoactive substance belonging to the amphetamine class.</p>Formula:C14H24ClNO2Color and Shape:SolidMolecular weight:273.8Methyl piperate
CAS:<p>Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibition</p>Formula:C13H12O4Purity:98%Color and Shape:SolidMolecular weight:232.23Rapastinel acetate
CAS:<p>Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.</p>Formula:C20H35N5O8Purity:99.6%Color and Shape:SoildMolecular weight:473.52(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Formula:C10H10ClNO6Purity:99.53% - 99.9%Color and Shape:SoildMolecular weight:275.64Pyrazolam
CAS:<p>Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.</p>Formula:C16H12BrN5Color and Shape:SolidMolecular weight:354.2STX-107
CAS:<p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>Formula:C18H10FN3SPurity:99.17%Color and Shape:SolidMolecular weight:319.36LE 300
CAS:<p>LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.</p>Formula:C20H22N2Purity:97.91% - 98.79%Color and Shape:SolidMolecular weight:290.4Anti-inflammatory agent 52
<p>Anti-inflammatory agent 52 (compound 7j) is an orally active, selective COX-2 inhibitor with the capability to induce G2/M phase arrest and exhibit anti-HT29</p>Formula:C24H21ClN2O3SPurity:98%Color and Shape:SolidMolecular weight:452.95COX-2-IN-31
<p>COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 μM).</p>Formula:C17H16N6O4SPurity:98%Color and Shape:SolidMolecular weight:400.41MmTx2 toxin
<p>MmTx2 toxin, extracted from the venom of the coral snake, serves as a modulator of the GABA A receptor, increasing its responsiveness to agonists.</p>Formula:C295H450N94O97S10Purity:98%Color and Shape:SolidMolecular weight:7185.95Lysyl hydroxylase 2-IN-2
<p>Lysyl Hydroxylase 2-IN-2 (compound 13) is a potent inhibitor of Lysyl Hydroxylase 2 (LH2), exhibiting an IC50 of approximately 500 nM.</p>Formula:C19H21N3O2Purity:98%Color and Shape:SolidMolecular weight:323.39NMDA receptor antagonist 6
<p>NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotective</p>Formula:C25H23NO2Purity:98%Color and Shape:SolidMolecular weight:369.46Arotinolol hydrochloride
CAS:<p>Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.</p>Formula:C15H22ClN3O2S3Purity:99.84%Color and Shape:SolidMolecular weight:408C18 L-erythro Ceramide (d18:1/18:0)
CAS:<p>C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.</p>Formula:C36H71NO3Color and Shape:SolidMolecular weight:565.95(-)-2-Phenylpropylamine
CAS:<p>(-)-2-Phenylpropylamine ((S)-2-Phenylpropylamine) (compound 3b) functions as an inhibitor for both MAO-A and MAO-B, with Ki values of 584 μM and 156 μM, respectively.</p>Formula:C9H13NColor and Shape:SolidMolecular weight:135.21RuBi-Nicotine
CAS:<p>Nicotinic receptor agonist</p>Formula:C40H44Cl2N8RuPurity:98%Color and Shape:SolidMolecular weight:808.81Pyrantel hydrochloride
CAS:<p>Pyrantel hydrochloride is the hydrochloride form of Pyrantel. Pyrantel is is an anthelmintic and a nicotinic acetylcholine receptor (nAChR) agonist.</p>Formula:C11H15ClN2SPurity:98.01%Color and Shape:SoildMolecular weight:242.77Timegadine hydrochloride
CAS:<p>Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine. It is an orally active inhibitor of COX and lipo-oxygenase, effectively suppressing COX in rabbit platelets and rat brain with IC50 values of 5 nM and 20 μM, respectively, and inhibiting lipo-oxygenase in horse and rabbit platelets with an IC50 of 100 μM. Timegadine hydrochloride also exhibits anti-arthritis activity.</p>Formula:C20H24ClN5SColor and Shape:SolidMolecular weight:401.96Pridinol hydrochloride
CAS:<p>Pridinolhydrochloride is the hydrochloride form of Pridinol. Pridinol hydrochloride is an orally active anticholinergic agent, which can also be used as a muscle relaxant.</p>Formula:C20H26ClNOColor and Shape:SolidMolecular weight:331.88γ-DGG TFA
CAS:<p>Gamma-DGG TFA is an antagonist of excitatory amino acids that can inhibit depolarization induced by NMDA, Kainate, and Quisqualate. In addition, it counteracts excitatory postsynaptic potentials (e.p.s.p.) in rat hippocampal slices.</p>Formula:C9H13F3N2O7Color and Shape:SolidMolecular weight:318.22-APB hydrochloride
CAS:<p>2-APB is an analog of 6-APB and falls under the category of benzofuran derivatives, known for its psychoactive properties. Certain benzofuran derivatives also exhibit monoamine oxidase-A (MAO-A) inhibitory activity.</p>Formula:C11H14ClNOColor and Shape:SolidMolecular weight:211.69Methalthiazide
CAS:<p>Methalthiazide enhances the activity of natural agonists of AMPA receptors and can be utilized in schizophrenia research.</p>Formula:C12H16ClN3O4S3Color and Shape:SolidMolecular weight:397.92Pirimiphos-ethyl
CAS:<p>Pirimiphos-ethyl is used as an organophosphorus pesticide.</p>Formula:C13H24N3O3PSPurity:98%Color and Shape:SolidMolecular weight:333.39Tropicamide
CAS:<p>Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.</p>Formula:C17H20N2O2Purity:99.78% - 99.94%Color and Shape:White PowderMolecular weight:284.352002-H20
CAS:<p>2002-H20 is an Aβ42-induced cytotoxicity inhibitor. It acts by binding the Alzheimer's Aβ peptide and reducing its cytotoxicity.</p>Formula:C20H15N3O3Purity:98%Color and Shape:SolidMolecular weight:345.358Ebiratide TFA
<p>Ebiratide (HOE-427) TFA is a derivative of ACTH4-9 that exerts its effect directly on the central nervous system, enhancing memory. Ebiratide TFA also promotes the metabolism of acetylcholine (ACh) in the rat brain.</p>Formula:C48H73N11O10S·xC2HF3O2Color and Shape:SolidMolecular weight:996.23 (free base)BSBM6
CAS:<p>BSBM6 is an inhibitor of Aβ aggregation and neuronal toxicity that acts by reversing the aggregation and toxicity of amyloid-β peptides.</p>Formula:C23H29N3O5Purity:98%Color and Shape:SolidMolecular weight:427.49(Rac)-5-Carboxy tolterodine
CAS:<p>(Rac)-5-Carboxy tolterodine is an inactive metabolite of Tolterodine, which acts as a muscarinic acetylcholine receptor antagonist.</p>Formula:C22H29NO3Color and Shape:SolidMolecular weight:355.47Emamectin B1a
CAS:<p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>Formula:C49H75NO13Color and Shape:SolidMolecular weight:886.133Fentonium bromide
CAS:<p>Fentonium bromide is a biochemical.</p>Formula:C31H34BrNO4Color and Shape:SolidMolecular weight:564.51Imagabalin
CAS:<p>Imagabalin is an active compound used in the study of neurological diseases.</p>Formula:C9H19NO2Color and Shape:SolidMolecular weight:173.25(+)-Coclaurine hydrochloride
CAS:<p>(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.</p>Formula:C17H20ClNO3Purity:98%Color and Shape:SolidMolecular weight:321.8FGIN-1-43
CAS:<p>FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.</p>Formula:C28H36Cl2N2OPurity:99.57%Color and Shape:SolidMolecular weight:487.5(Iso)-Atagabalin HCl
CAS:<p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>Formula:C10H20ClNO2Purity:99.26% - >99.99%Color and Shape:SoildMolecular weight:221.72[D-Trp7,9,10]-Substance P
CAS:<p>Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.</p>Formula:C79H105N21O13SPurity:98%Color and Shape:SolidMolecular weight:1588.89TMPH
CAS:<p>TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.</p>Formula:C16H31NO2Purity:99.78%Color and Shape:SoildMolecular weight:269.42Suntinorexton
CAS:<p>Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.</p>Formula:C23H28F2N2O4SPurity:99.89%Color and Shape:SolidMolecular weight:466.54(Iso)-Landipirdine
CAS:<p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>Formula:C18H19FN2O3SPurity:98.50%Color and Shape:SoildMolecular weight:362.42Polyglutamine binding peptide 1
CAS:<p>Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ). It effectively inhibits polyQ protein aggregation in vitro and prevents polyQ-induced cell death in cell cultures.</p>Formula:C72H90N16O16Color and Shape:SolidMolecular weight:1435.58I2-IRs ligand-1
<p>I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.</p>Formula:C21H23ClFN2O4PColor and Shape:SolidMolecular weight:452.845-HT6R antagonist 6
<p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>Formula:C24H26N4O2SColor and Shape:SolidMolecular weight:434.55TIM-098a
<p>TIM-098a is a selective AAK1 inhibitor with an IC50 of 0.24 µM. It does not inhibit CaMKK isoforms. By inhibiting AAK1 kinase activity, TIM-098a disrupts AAK1-regulated endocytosis.</p>Formula:C18H11N3O2Molecular weight:301.08513Amyloid β Peptide (42-1)(human) acetate
<p>Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42).</p>Purity:95.20%Color and Shape:SoildhAChE/hBuChE/GSK-3β-IN-1
<p>hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a multi-target compound designed for Alzheimer's treatment capable of crossing the blood-brain barrier. It inhibits hAChE with an IC50 of 28.88 nM, hBuChE with an IC50 of 131.90 nM, and GSK-3β with an IC50 of 51.42 nM. Additionally, it acts as an inhibitor of tau protein and Aβ protein aggregation.</p>Formula:C19H15NO4Color and Shape:SolidMolecular weight:321.327AChE-IN-49
<p>AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.</p>Formula:C31H28BrClN2O3Molecular weight:590.09718ACHE Inhibitor 12
CAS:<p>ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.</p>Formula:C11H12OPurity:98.71%Color and Shape:SolidMolecular weight:160.21Calmodulin Kinase IINtide, Myristoylated
<p>Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].</p>Formula:C156H275N47O43Purity:98%Color and Shape:SolidMolecular weight:3497.14(S)-AMPA HCl
<p>(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.</p>Formula:C7H11ClN2O4Purity:99.18%Color and Shape:SolidMolecular weight:222.63AChE-IN-60
<p>AChE-IN-60 (compound 6k) is a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 27 nM and 43 nM, respectively. It also inhibits monoamine oxidase MAO-A and MAO-B, with IC50 values of 353 nM and 716 nM, respectively.</p>Formula:C24H29N3O4S3Molecular weight:519.13202Org 13011
CAS:<p>Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.</p>Formula:C18H25F3N4OPurity:98.02%Color and Shape:SoildMolecular weight:370.41SB 216641
CAS:<p>SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.</p>Formula:C28H30N4O4Purity:98.09%Color and Shape:SolidMolecular weight:486.56Brexanolone caprilcerbate
CAS:<p>Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.</p>Formula:C48H78O12Color and Shape:SolidMolecular weight:847.13AChE/BChE-IN-22
<p>AChE/BChE-IN-22 (compound 7) exhibits competitive inhibition against both AChE and BChE enzymes, with inhibition constants of 28.18 μM and 41.74 μM respectively.</p>Formula:C14H11F3N2O4SColor and Shape:SolidMolecular weight:360.31MAO-B-IN-36
<p>MAO-B-IN-36 (Compound A6) is an effective MAO-B inhibitor with an IC50 of 13 nM.</p>Formula:C20H14O3Color and Shape:SolidMolecular weight:302.32Inaperisone
CAS:<p>Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.</p>Formula:C16H23NOPurity:99.48%Color and Shape:SolidMolecular weight:245.36Femoxetine
CAS:<p>Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.</p>Formula:C20H25NO2Purity:99.1% - 99.35%Color and Shape:SolidMolecular weight:311.42CPN-351
CAS:<p>CPN-351 (compound 9a) is a pentapeptide that acts as a selective antagonist for human NMUR1, with a pA2 value of 7.35. It exhibits ten times greater antagonistic activity toward human NMUR1 compared to NMUR2. CPN-351 is applicable in inflammation research.</p>Formula:C45H61N13O6SMolecular weight:912.11β-Amyloid (35-25)
CAS:<p>β-Amyloid (35-25) is the reverse sequence of β-Amyloid (25-35).</p>Formula:C45H81N13O14SMolecular weight:1060.27SKF-83566 hydrochloride
CAS:<p>SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.</p>Formula:C17H19BrClNOPurity:99.27%Color and Shape:SoildMolecular weight:368.69Orexin A (human, rat, mouse) acetate
<p>Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.</p>Formula:C154H247N47O46S4Color and Shape:SolidMolecular weight:3621.15FITC-β-Ala-Amyloid β-Protein (1-42)
CAS:<p>FITC-β-Ala-Amyloid β-Protein (1-42) is a polypeptide identified through peptide screening. This screening method predominantly utilizes immunoassays to gather active polypeptides and is used in studying protein interactions, conducting functional analyses, and screening antigen epitopes, with particular application in the research and development of active molecules.</p>Formula:C227H327N57O66S2Molecular weight:4971.34251Tiaspirone hydrochloride
CAS:<p>Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.</p>Formula:C24H33ClN4O2SPurity:99.87%Color and Shape:SoildMolecular weight:477.06Brexpiprazole S-oxide
CAS:<p>Brexpiprazole S-oxide is the main metabolite of Brexpiprazole, a human 5-HT1A and dopamine receptor partial agonist (Ki: 0.12, 0.3 nM).</p>Formula:C25H27N3O3SPurity:98%Color and Shape:SolidMolecular weight:449.57Nemifitide diTFA
CAS:<p>Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.</p>Formula:C37H45F7N10O10Purity:99.78% - 99.84%Color and Shape:SolidMolecular weight:922.85-HT1AR agonist 2
<p>5-HT1AR Agonist 2 (Compound 4f) is a potent agonist of the 5-HT1A receptor with a Ki value of 10.0 nM. It also binds to SERT, D2, and 5-HT6 receptors with Ki values of 2.8 nM, 23 nM, and 192 nM, respectively. Furthermore, this compound demonstrates stability in microsomes and induces hypothermia in mice.</p>Formula:C31H31N5O3Color and Shape:SolidMolecular weight:521.61VU0483605
CAS:<p>VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.</p>Formula:C20H10Cl3N3O3Purity:99.61%Color and Shape:SolidMolecular weight:446.67Aβ1-14-εK-KKK-MvF5 Th
<p>Aβ1-14-εK-KKK-MvF5 Th (UB311 immunogen I) is a biologically active peptide and one of the Aβ1–14 targeting peptides (B-cell epitope) used in UB-311.</p>Formula:C199H318N56O55Molecular weight:4372.38081Furosemide
CAS:<p>Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.</p>Formula:C12H11ClN2O5SPurity:99.32% - 99.89%Color and Shape:Crystals From Aqueous Ethanol Tasteless (Ntp 1992)Molecular weight:330.744Binospirone
CAS:<p>Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.</p>Formula:C20H26N2O4Purity:97.57% - 98.96%Color and Shape:SoildMolecular weight:358.43Endosulfan I
CAS:<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Formula:C9H6Cl6O3SPurity:99.86%Color and Shape:SolidMolecular weight:406.93rac Desmethyl Citalopram Hydrochloride
CAS:<p>rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.</p>Formula:C19H20ClFN2OPurity:99.24%Color and Shape:SolidMolecular weight:346.83Lu AF27139
CAS:<p>Lu AF27139: P2X7 receptor antagonist; IC50: 12 nM (human), 2.4 nM (rat); Ki: 22 (mouse), 54 (human), 13 nM (rat); for CNS research.</p>Formula:C21H19ClF3N5O2SPurity:99.96%Color and Shape:SolidMolecular weight:497.92Tiquizium
CAS:<p>Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.</p>Formula:C19H24NS2Purity:99.82%Color and Shape:SolidMolecular weight:330.53COX-1/2-IN-4
<p>COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.</p>Formula:C22H24N2O2SPurity:98%Color and Shape:SolidMolecular weight:380.5NMDA receptor antagonist 8
<p>Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM.</p>Formula:C22H27N3OPurity:98%Color and Shape:SolidMolecular weight:349.47COX-2-IN-33
<p>COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.</p>Formula:C20H13ClF3N5O4Purity:98%Color and Shape:SolidMolecular weight:479.8nAChR agonist 2
CAS:<p>Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,</p>Formula:C11H16N2Color and Shape:SolidMolecular weight:176.263MAO-B-IN-37
CAS:<p>MAO-B-IN-37 (Compound 37) is a derivative of TT01001 and acts as a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 270 nM. It exhibits good metabolic stability in mouse microsomes and shows strong affinity for human serum albumin.</p>Formula:C14H12FN3O3Color and Shape:SolidMolecular weight:289.266-Fluoro-N,N-diethyltryptamine
CAS:<p>6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.</p>Formula:C14H19FN2Color and Shape:SolidMolecular weight:234.31Orexin B, human
CAS:<p>Orexin B, human agonizes Orexin receptors (OX1 Ki=420 nM, OX2 Ki=36 nM), promotes feeding in rats, and is a neuropeptide.</p>Formula:C123H212N44O35SPurity:98%Color and Shape:SolidMolecular weight:2899.34Br-PBTC
CAS:<p>Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.</p>Formula:C14H15BrN2OSColor and Shape:SolidMolecular weight:339.25TC-2559 difumarate
CAS:<p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>Formula:C20H26N2O9Color and Shape:SolidMolecular weight:438.43Methamnetamine hydrochloride
CAS:<p>Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.</p>Formula:C14H18ClNColor and Shape:SolidMolecular weight:235.757-Methyl DMT
CAS:<p>7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.</p>Formula:C13H18N2Color and Shape:SolidMolecular weight:202.3Rilmazolam
CAS:<p>Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.</p>Formula:C19H15Cl2N5OColor and Shape:SolidMolecular weight:400.2625E-NBOMe hydrochloride
CAS:<p>25E-NBOMe hydrochloride is a derivative of 2C-E, featuring an N-(2-methoxybenzyl) addition to the amine group, and acts as a selective agonist of the 5-HT2A receptor.</p>Formula:C20H28ClNO3Color and Shape:SolidMolecular weight:365.89SB 699551
CAS:<p>SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.</p>Formula:C34H45N3OPurity:99.83%Molecular weight:511.74COX-1/2-IN-9
<p>COX-1/2-IN-9 (Compound 3n) serves as a selective and potent inhibitor of both COX-1 and COX-2, demonstrating IC 50 values of 0.031 µM for COX-1 and 0.01 µM for COX-2. This compound exhibits antibacterial and anti-inflammatory properties, effectively targeting MRSA 1478 (MIC=50 μg/mL) and multidrug-resistant S. lentus (MIC=50 μg/mL). Furthermore, COX-1/2-IN-9 shows promise in relieving MRSA-induced pneumonia in conditions of compromised immunity.</p>Formula:C30H20IN9O13S2Color and Shape:SolidMolecular weight:905.57β-Amyloid (1-11)
CAS:<p>Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid</p>Formula:C56H76N16O22Purity:98%Color and Shape:SolidMolecular weight:1325.3Otaplimastat HCl
CAS:<p>Otaplimastat HCl is an MMP inhibitor reducing NMDA-mediated excitotoxicity and oxidative stress, restoring TIMP levels, and protecting vascular permeability.</p>Formula:C28H35ClN6O5Purity:100%Molecular weight:571.07Triazolomethylindole-3-acetic acid
CAS:<p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>Formula:C13H12N4O2Color and Shape:SolidMolecular weight:256.26COX-2-IN-46
<p>COX-2-IN-46 (compound 5m) serves as a potent anti-inflammatory and analgesic agent. It demonstrates a significant inhibitory action on COX-2, with an IC 50 value of 87.74 nM.</p>Formula:C28H19F2N3SColor and Shape:SolidMolecular weight:467.53AChE/BChE-IN-25
<p>AChE/BChE-IN-25 (Compound 6e) is an orally active inhibitor of hAChE and eqBChE, with IC50 values of 7.9 nM and 0.79 nM, respectively. This compound exhibits antioxidant activity, effective in scavenging free radicals with an IC50 of 22.91 μM. AChE/BChE-IN-25 demonstrates neuroprotective effects by reducing mitochondrial and cellular oxidative stress in a Drosophila Alzheimer's model and improves spatial and cognitive memory impairments induced by Scopolamine in mouse models.</p>Formula:C21H24ClN3O2Color and Shape:SolidMolecular weight:385.89β-Amyloid (18-28)
CAS:<p>Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.</p>Formula:C55H81N13O18Purity:98%Color and Shape:SolidMolecular weight:1212.31TAT-CN21
<p>TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.</p>Formula:C169H303N69O43Color and Shape:SolidMolecular weight:3989.65Dual AChE-MAO B-IN-3
<p>Compound C10 is a potent dual AChE/MAO-B inhibitor with IC50s of 0.58μM (AChE) and 0.41μM (MAO-B), useful in Alzheimer's research.</p>Formula:C30H26F3NO3Color and Shape:SolidMolecular weight:505.534-hydroxy DiPT hydrochloride
CAS:<p>4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.</p>Formula:C16H25ClN2OColor and Shape:SolidMolecular weight:296.84Argiotoxin 636
CAS:<p>Argiotoxin 636 is a toxin and serves as a non-specific, non-competitive, and effective antagonist of ionotropic glutamate receptors (iGluR). It inhibits excitatory synaptic transmission in neurons and has paralyzing and muscle relaxant effects. Argiotoxin 636 can be utilized for research in neurological disorders.</p>Formula:C29H52N10O6Color and Shape:SolidMolecular weight:636.795-HT2A receptor agonist-6
CAS:<p>5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.</p>Formula:C18H19N3O3Color and Shape:SolidMolecular weight:325.363-Chloroamphetamine hydrochloride
CAS:<p>3-Chloroamphetamine hydrochloride is a derivative of amphetamine that acts as a central nervous system stimulant by releasing serotonin and dopamine.</p>Formula:C9H13Cl2NColor and Shape:SolidMolecular weight:206.11AChE/BChE-IN-11
CAS:<p>AChE/BChE-IN-11, natural from artichoke leaves, inhibits AChE and BChE (IC50: 70/71 μM) for Alzheimer's research.</p>Formula:C21H22O12Color and Shape:SolidMolecular weight:466.39Dicloromezotiaz
CAS:<p>Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.</p>Formula:C19H12Cl3N3O2SColor and Shape:SolidMolecular weight:452.74Melatonin-Tamoxifen Conjugate
<p>Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.</p>Formula:C47H58N4O4Color and Shape:SolidMolecular weight:742.99Cinazepam
CAS:<p>Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.</p>Formula:C19H14BrClN2O5Color and Shape:SolidMolecular weight:465.68p-Xylene bis(pyridinium bromide)
CAS:<p>p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.</p>Formula:C18H18Br2N2Color and Shape:SolidMolecular weight:422.16Multitarget AD inhibitor-1
CAS:<p>Multitarget AD inhibitor-1: reversible, selective BuChE blocker, inhibits β-secretase and amyloid/tau aggregation, promising for Alzheimer's research.</p>Formula:C29H38N2OColor and Shape:SolidMolecular weight:430.636β-Amyloid (29-40)
CAS:<p>β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties</p>Formula:C49H88N12O13SPurity:98%Color and Shape:SolidMolecular weight:1085.36Amyloid β-Protein (1-24)
CAS:<p>Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.</p>Formula:C130H183N35O40Molecular weight:2876.05nAChR modulator-1
CAS:<p>nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Formula:C12H8ClN3O2Color and Shape:SolidMolecular weight:261.66AC1-IN-1
CAS:<p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>Formula:C18H18FN5O2Purity:99.89%Color and Shape:SolidMolecular weight:355.37BChE-IN-10
CAS:<p>BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.</p>Formula:C23H20O5Color and Shape:SolidMolecular weight:376.4γ-Secretase modulator 10
CAS:<p>γ-Secretase modulator 10 is a novel γ-secretase modulator.</p>Formula:C25H23F3N4O2Color and Shape:SolidMolecular weight:468.48MGS0274
CAS:<p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>Formula:C21H32FNO7Color and Shape:SolidMolecular weight:429.485CUR-IPA
<p>CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.</p>Formula:C43H38N2O8Color and Shape:SolidMolecular weight:710.77BuChE-IN-11
<p>BuChE-IN-11 (Compound 3b-1) is a selective inhibitor of BuChE with an IC50 of 0.44 μM for hBuChE. The compound demonstrates high brain-blood barrier permeability and possesses free radical scavenging capabilities, indicating significant antioxidant activity. BuChE-IN-11 interacts with the choline binding site, the acyl binding site, and the peripheral anionic site, showing submicromolar inhibitory activity against BuChE and preventing the self-aggregation of β-amyloid protein (Aβ). This compound holds promise for research in the field of Alzheimer's disease.</p>Formula:C28H27FN4O2Molecular weight:470.2118Bencycloquidium Bromide
CAS:<p>Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.</p>Formula:C21H32BrNO2Color and Shape:SolidMolecular weight:410.39Navicixizumab
CAS:<p>Navicixizumab, a bispecific VEGF/DLL4 inhibitor, pairs with Paclitaxel in ovarian and other cancer research.</p>Color and Shape:LiquidmHTT-IN-1
CAS:<p>mHTT-IN-1 is a potent inhibitor of toxic mHTT, linked to Huntington's disease, with an EC50 of 46 nM.</p>Formula:C18H19N7OSColor and Shape:SolidMolecular weight:381.45MR33317
<p>MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.</p>Formula:C22H28ClN3O2Molecular weight:401.187Flufiprole
CAS:<p>Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.</p>Formula:C16H10Cl2F6N4OSColor and Shape:SolidMolecular weight:491.24TRV-7019
CAS:<p>TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.</p>Formula:C14H12INO3Color and Shape:SolidMolecular weight:369.15LPYFD-NH2
CAS:<p>neuroprotective peptide that binds to amyloid beta (Aβ)</p>Formula:C33H44N6O8Purity:98%Color and Shape:SolidMolecular weight:652.74TET-13
<p>TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.</p>Formula:C15H16N2O3SColor and Shape:SolidMolecular weight:304.36Millmerranone A
<p>Millmerranone A shows the acetylcholinesterase inhibitory property.</p>Formula:C27H28O9Color and Shape:SolidMolecular weight:496.51Cinanserin hydrochloride
CAS:<p>Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.</p>Formula:C20H25ClN2OSPurity:99.57%Color and Shape:SolidMolecular weight:376.94Dehydrodiscretamine chloride
CAS:<p>Dehydrodiscretamine chloride, a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibits IC50 values of 17.8 μM and 118.8 μM,</p>Formula:C19H18ClNO4Color and Shape:SolidMolecular weight:359.8(S)-3,4-DCPG
CAS:<p>(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).</p>Formula:C10H9NO6Purity:98%Color and Shape:SolidMolecular weight:239.18(-)-Coclaurine hydrochloride
CAS:<p>(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.</p>Formula:C17H20ClNO3Purity:99.07%Color and Shape:SoildMolecular weight:321.84-Hydroxy MPT
CAS:<p>4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.</p>Formula:C14H20N2OColor and Shape:SolidMolecular weight:232.32AChE-IN-29
<p>AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric</p>Formula:C18H19BrN2O2Color and Shape:SolidMolecular weight:375.26p-MPPF
CAS:<p>p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.</p>Formula:C25H27FN4O2Purity:99.92%Color and Shape:SolidMolecular weight:434.51LP 12 hydrochloride
CAS:<p>LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).</p>Formula:C32H40ClN3OColor and Shape:SolidMolecular weight:518.14RuBi-GABA
CAS:<p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>Formula:C42H39F6N5O2P2RuPurity:98%Color and Shape:SolidMolecular weight:922.81H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS:<p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>Formula:C26H34N2O7Purity:99.44%Color and Shape:SoildMolecular weight:486.56Mosapride citrate dihydrate
CAS:<p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>Formula:C27H35ClFN3O11Purity:98%Color and Shape:SolidMolecular weight:632.04AHN-683
CAS:<p>AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.</p>Formula:C42H32FN3O7Purity:98%Color and Shape:SolidMolecular weight:709.72Anabaseine
CAS:<p>Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.</p>Formula:C10H12N2Color and Shape:SolidMolecular weight:160.224-Methoxyphenyl isothiocyanate
CAS:<p>4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.</p>Formula:C8H7NOSColor and Shape:SolidMolecular weight:165.21CALP2
CAS:<p>CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.</p>Formula:C68H104N14O13SPurity:98%Color and Shape:SolidMolecular weight:1357.72Lu AE51090
CAS:<p>Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.</p>Formula:C24H29N3O3Purity:99.57%Color and Shape:SolidMolecular weight:407.51AChE-IN-86
<p>AChE-IN-86 (Compound 6f) is an inhibitor of acetylcholinesterase (AChE) with an IC50 value of 25.33 μg/mL. This compound exerts its inhibitory effects by forming hydrogen bonds, π-π, and π-alkyl interactions with amino acid residues at the key catalytic site of AChE. AChE-IN-86 can be utilized in Alzheimer's disease research.</p>Formula:C28H27N3O6SColor and Shape:SolidMolecular weight:533.595AChE-IN-27
CAS:<p>AChE-IN-27 is a small molecule used for high-throughput assays.</p>Formula:C20H14N2O3Purity:98.54%Color and Shape:SolidMolecular weight:330.34SIB 1553A
CAS:<p>SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.</p>Formula:C13H19NOSPurity:99.79%Color and Shape:SoildMolecular weight:237.36Syk Inhibitor II hydrochloride
CAS:<p>Syk signaling is key in lupus. Syk inhibitors reduce inflammation and sepsis severity in FcgRIIb-/- mice, lowering cytokines and organ damage.</p>Formula:C14H16ClF3N6OPurity:99.05%Color and Shape:SolidMolecular weight:376.77(S)-UFR2709 hydrochloride
CAS:<p>(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety & alcohol intake in rats, studies nicotine addiction.</p>Formula:C13H18ClNO2Purity:98.94%Color and Shape:SolidMolecular weight:255.74LY3027788
CAS:<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Formula:C25H31F2NO11SColor and Shape:SolidMolecular weight:591.58(±)-Acetylcarnitine chloride
CAS:<p>(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with neuroprotective properties and can be used in studies of neuritis.</p>Formula:C9H18ClNO4Purity:99.98%Color and Shape:White Crystalline PowderMolecular weight:239.7MAO-B-IN-20
<p>MAO-B-IN-20, potent with 0.037 μM IC50, is stable and BBB permeable, useful for Parkinson's research.</p>Formula:C20H18F2N2O2Color and Shape:SolidMolecular weight:356.37LRRK2 inhibitor 1
CAS:<p>LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.</p>Formula:C20H23N5O4Purity:99.94%Color and Shape:SolidMolecular weight:397.43Adatanserin hydrochloride
CAS:<p>Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.</p>Formula:C21H32ClN5OPurity:99.64%Color and Shape:SolidMolecular weight:405.961,8-Cineole
CAS:<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Formula:C10H18OPurity:97.44% - 97.44%Color and Shape:SolidMolecular weight:154.25SB 258585
CAS:<p>SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.</p>Formula:C18H22IN3O3SPurity:99.8%Color and Shape:SoildMolecular weight:487.36DOAM
CAS:<p>DOAM is an antagonist of the 5-HT2 receptor.</p>Formula:C16H27NO2Color and Shape:SolidMolecular weight:265.39SPL-707
CAS:<p>SPL-707 is an effective and selective signal peptide peptidase-like 2a inhibitor (IC50: 80 nM).</p>Formula:C27H28FN5O4Purity:98%Color and Shape:SolidMolecular weight:505.54RS 56812
CAS:<p>RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.</p>Formula:C18H21N3O2Purity:99.38%Color and Shape:SoildMolecular weight:311.38CIA-1 (Free base)
CAS:<p>CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.</p>Formula:C17H19N3O2SPurity:99%Color and Shape:SolidMolecular weight:329.42TIP 39, Tuberoinfundibular Neuropeptide
CAS:<p>TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.</p>Formula:C202H325N61O54SPurity:98%Color and Shape:SolidMolecular weight:4504.26,7-dimethylisatin
CAS:<p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>Formula:C10H9NO2Purity:98.98%Color and Shape:SolidMolecular weight:175.18β-Secretase inhibitor-STA
CAS:<p>BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor</p>Formula:C73H118N16O27Purity:98%Color and Shape:SolidMolecular weight:1651.81Ro 12-5637
CAS:<p>Ro 12-5637 is a metabolite of moclobemide.</p>Formula:C13H17ClN2O3Color and Shape:SolidMolecular weight:284.74GRGDSPK acetate
CAS:<p>GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.</p>Formula:C30H53N11O13Purity:97.9%Color and Shape:SoildMolecular weight:775.815-HT2C agonist-4
CAS:<p>Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.</p>Formula:C24H25N5OColor and Shape:SolidMolecular weight:399.49Emraclidine
CAS:<p>Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.</p>Formula:C20H21F3N4OPurity:99.96%Color and Shape:SolidMolecular weight:390.4TC-2216
CAS:<p>TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.</p>Formula:C12H17N3Purity:99.33%Color and Shape:SolidMolecular weight:203.28LY-53857 free base
CAS:<p>LY-53857 free base is a bioactive chemical.</p>Formula:C23H32N2O3Color and Shape:SolidMolecular weight:384.51NT 13 acetate
<p>NT 13 acetate is a partial agonist of NMDA receptor and can be used for research on depression, anxiety, and other related diseases.</p>Formula:C20H34N4O9Purity:98%Color and Shape:SolidMolecular weight:474.515β-Cholanic acid
CAS:<p>5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.</p>Formula:C24H40O2Purity:98.91% - 99.89%Color and Shape:SoildMolecular weight:360.57NF023 hexasodium
CAS:<p>NF023 hexasodium is a selective and competitive P2X1 receptor antagonist, with IC50 values of 0.21 μM, 28.9 μM, > 50 μM and > 100 μM for human P2X1, P2X3, P2X2</p>Formula:C35H26N4Na6O21S6Purity:98%Color and Shape:SolidMolecular weight:1168.92α-Conotoxin PIA TFA
<p>α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.</p>Formula:C81H126F3N27O27S4Purity:98.81%Color and Shape:SolidMolecular weight:2095.3γ-Secretase Modulators
CAS:<p>gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.</p>Formula:C26H24F3N3O3Purity:98%Color and Shape:SolidMolecular weight:483.484-fluoro MBZP
CAS:<p>4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.</p>Formula:C12H17FN2Color and Shape:SolidMolecular weight:208.28
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