Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Found 562 products of "Cyclooxygenase (COX) Inhibitors"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Lonazolac Calcium
CAS:<p>Lonazolac Calcium, a nonsteroidal anti-inflammatory drug (NSAID), is used to treat inflammation and pain.</p>Formula:C34H24CaCl2N4O4Purity:98%Color and Shape:SolidMolecular weight:663.56C2 Ceramide (d14:1/2:0)
CAS:<p>C2 Ceramide (d14:1/2:0), a bioactive sphingolipid, causes lipotoxic cardiomyopathy when fed to Drosophila at 100 μM.</p>Formula:C16H31NO3Color and Shape:SolidMolecular weight:285.42COX-2/NLRP3-IN-1
<p>COX-2/NLRP3-IN-1 (Compound 6k) is an inhibitor that targets COX-2 and NLRP3, exhibiting an IC50 value of 1.53 μM for COX-2. This compound exerts anti-inflammatory effects by inhibiting the NF-κB/NLRP3 signaling pathway.</p>Formula:C24H19Cl2N5OSMolecular weight:495.06874Chloranthalactone B
CAS:<p>Chloranthalactone B, a sesquiterpenoid from Sarcandra glabra, inhibits inflammation via AP-1 & p38 MAPK.</p>Formula:C15H16O3Color and Shape:SolidMolecular weight:244.29Anti-inflammatory agent 78
<p>Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. It effectively inhibits PGE2, PGE1, COX-2, and COX-1. Additionally, Anti-inflammatory agent 78 suppresses the release of NO in LPS-stimulated RAW 264.7 cell lines.</p>Formula:C19H14ClNO4Molecular weight:355.06114NF157
CAS:<p>NF157, a selective P2Y11 antagonist with pKi 7.35, lowers MMP-3/MMP-13, aiding OA treatment; IC50s: P2Y11 463 nM, P2Y1 1811 μM, P2Y2 170 μM.</p>Formula:C49H28F2N6Na6O23S6Purity:98%Color and Shape:SolidMolecular weight:1437.1Fentiazac
CAS:<p>Fentiazac (BR-700) is an oral NSAID for pain, inflammation, fever, studied for arthritis and tendonitis.</p>Formula:C17H12ClNO2SPurity:99.83%Color and Shape:SolidMolecular weight:329.8Parecoxib sodium
CAS:<p>Parecoxib: COX2 inhibitor, treats short-term postoperative pain, water-soluble, injectable, valdecoxib prodrug, less GI toxicity than ketorolac.</p>Formula:C19H18N2NaO4SPurity:98%Color and Shape:SolidMolecular weight:393.41Bardoxolone Methyl
CAS:Formula:C32H43NO4Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:505.70Loxoprofen Sodium Salt Dihydrate
CAS:Formula:C15H17NaO3·2H2OPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:304.32Etoricoxib
CAS:Formula:C18H15ClN2O2SPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:358.84Butyl 2-[[3-(Trifluoromethyl)phenyl]amino]benzoate
CAS:Formula:C18H18F3NO2Purity:>98.0%(HPLC)(N)Color and Shape:Colorless to Yellow clear liquidMolecular weight:337.34(S)-(+)-Ibuprofen D3
CAS:<p>(S)-(+)-Ibuprofen D3, deuterium-labeled S-enantiomer, COX-1/2 inhibitor with IC50s of 2.1 and 1.6 μM.</p>Formula:C13H18O2Purity:98%Color and Shape:SolidMolecular weight:209.3Etoricoxib-d4
CAS:<p>Etoricoxib-d4 is the 2H-labeled form of Etoricoxib. Etoricoxib is a COX-2 inhibitor with antipyretic, analgesic, and potential anticancer properties.</p>Formula:C18H11D4ClN2O2SPurity:>99.99%Color and Shape:SolidMolecular weight:362.87SC-560
CAS:Formula:C17H12ClF3N2OPurity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:352.74Valdecoxib
CAS:Formula:C16H14N2O3SPurity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:314.36Ketorolac Tromethamine
CAS:Formula:C15H13NO3·C4H11NO3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:376.41Tenoxicam
CAS:Formula:C13H11N3O4S2Purity:>98.0%(HPLC)(N)Color and Shape:White to Yellow to Green powder to crystalMolecular weight:337.37Nimesulide D5
CAS:<p>Nimesulide D5 is a deuterium labeled Nimesulide. Nimesulide is a selective inhibitor OF COX-2(IC50s of 70 nM-70 μM)</p>Formula:C13H12N2O5SPurity:98%Color and Shape:SolidMolecular weight:313.34Parecoxib
CAS:Formula:C19H18N2O4SPurity:>97.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:370.42
![Butyl 2-[[3-(Trifluoromethyl)phenyl]amino]benzoate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb-webp%2FB5391.webp&w=3840&q=75)
