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Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.

Found 562 products of "Cyclooxygenase (COX) Inhibitors"

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  • Tinoridine hydrochloride
    Targetmol
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    Tinoridine hydrochloride

    CAS:
    <p>Tinoridine HCl is an NSAID that inhibits lipid peroxides and renin release, unlike indomethacin and corticosteroids.</p>
    Formula:C17H21ClN2O2S
    Purity:97.49%
    Color and Shape:Solid
    Molecular weight:352.88

    Ref: TM-T4313

  • Isofraxidin
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    Isofraxidin

    CAS:
    <p>Isofraxidin combats leukemia, ALI, and inflammation by modulating ROS, COX-2, PGE2, TNF-α, and p38/ERK1/2 pathways.</p>
    Formula:C11H10O5
    Purity:99.51% - ≥95%
    Color and Shape:Solid
    Molecular weight:222.19

    Ref: TM-T5S0045

  • Tolmetin
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    Tolmetin

    CAS:
    <p>Tolmetin (Tolectin) NSAID; acts as a cyclooxygenase inhibitor; classified as an anti-inflammatory.</p>
    Formula:C15H15NO3
    Purity:99.74% - >99.99%
    Color and Shape:Off-White Crystalline Power
    Molecular weight:257.28

    Ref: TM-T2550

  • [10]-Shogaol
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    [10]-Shogaol

    CAS:
    <p>[10]-Shogaol (10-Shogaol) is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.</p>
    Formula:C21H32O3
    Purity:97.64% - 98.65%
    Color and Shape:Solid
    Molecular weight:332.48

    Ref: TM-T5431

  • α-Spinasterol
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    α-Spinasterol

    CAS:
    <p>α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects.</p>
    Formula:C29H48O
    Purity:97.03% - 99.58%
    Color and Shape:Solid
    Molecular weight:412.69

    Ref: TM-TN1377

  • Mofezolac
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    Mofezolac

    CAS:
    <p>Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index &gt; 6000</p>
    Formula:C19H17NO5
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:339.34

    Ref: TM-T5460

  • Firocoxib
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    Firocoxib

    CAS:
    <p>Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.</p>
    Formula:C17H20O5S
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:336.4

    Ref: TM-T7596

  • Parecoxib
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    Parecoxib

    CAS:
    <p>Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.</p>
    Formula:C19H18N2O4S
    Purity:99.71% - 99.78%
    Color and Shape:Solid
    Molecular weight:370.42

    Ref: TM-T1780

  • Tazofelone
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    Tazofelone

    CAS:
    <p>Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease.</p>
    Formula:C18H27NO2S
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:321.48

    Ref: TM-T22437

  • (E)-Ethyl p-methoxycinnamate
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    (E)-Ethyl p-methoxycinnamate

    CAS:
    <p>1. (E)-Ethyl p-methoxycinnamate (EPMC) is an anticarcinogenic agent. 2. (E)-Ethyl p-methoxycinnamate (EPMC) is a glutathion S tranferase inhibitor.</p>
    Formula:C12H14O3
    Purity:97.43%
    Color and Shape:Solid
    Molecular weight:206.24

    Ref: TM-T2S1625

  • RK33
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    RK33

    CAS:
    <p>"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."</p>
    Formula:C23H20N6O3
    Purity:99.04% - 99.72%
    Color and Shape:Solid
    Molecular weight:428.44

    Ref: TM-T6970

  • Cis-5-Dodecenoic Acid
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    Cis-5-Dodecenoic Acid

    CAS:
    <p>Cis-5-Dodecenoic Acid is a monounsaturated fatty acid that has a C12 chain as a backbone and a cis double bond at the C5 position.</p>
    Formula:C12H22O2
    Purity:98% - 99.37%
    Color and Shape:Solid
    Molecular weight:198.3

    Ref: TM-T8240

  • Madecassic acid
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    Madecassic acid

    CAS:
    <p>Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.</p>
    Formula:C30H48O6
    Purity:98.80% - 99.69%
    Color and Shape:Solid
    Molecular weight:504.7

    Ref: TM-T2758

  • Gnetol
    Targetmol
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    Gnetol

    CAS:
    <p>Gnetol inhibits butyrylcholinesterase (IC50: 1.3 μM), tyrosinase, melanin synthesis in B16 cells, and AA-induced platelet aggregation.</p>
    Formula:C14H12O4
    Purity:98.55% - ≥95%
    Color and Shape:Solid
    Molecular weight:244.24

    Ref: TM-T7052

  • Columbin
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    Columbin

    CAS:
    <p>Columbin: anti-inflammatory, prevents colon cancer, inhibits PLA2 in RBC dose-dependently.</p>
    Formula:C20H22O6
    Purity:99.34% - 99.74%
    Color and Shape:Solid
    Molecular weight:358.39

    Ref: TM-T4S0590

  • S-(+)-Marmesin
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    S-(+)-Marmesin

    CAS:
    <p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>
    Formula:C14H14O4
    Purity:98.00% - ≥98%
    Color and Shape:Solid
    Molecular weight:246.26

    Ref: TM-T5759

  • Losartan Carboxaldehyde
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    Losartan Carboxaldehyde

    CAS:
    <p>Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.</p>
    Formula:C22H21ClN6O
    Purity:99.1%
    Color and Shape:Solid
    Molecular weight:420.89

    Ref: TM-T7838

  • Esculentoside A
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    Esculentoside A

    CAS:
    <p>Esculentoside A dampens inflammation in ALI, modulates T cells, and could treat autoimmune diseases and BXSB mice by adjusting cytokines and renal cells.</p>
    Formula:C42H66O16
    Purity:98% - 99.85%
    Color and Shape:Solid
    Molecular weight:826.96

    Ref: TM-T3877

  • Isoorientin
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    Isoorientin

    CAS:
    <p>Isoorientin (Homoorientin) has antioxidant activity.</p>
    Formula:C21H20O11
    Purity:98.84% - 99.93%
    Color and Shape:Solid
    Molecular weight:448.38

    Ref: TM-T6S0722

  • Psoralidin
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    Psoralidin

    CAS:
    <p>Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.</p>
    Formula:C20H16O5
    Purity:98% - 99.61%
    Color and Shape:Solid
    Molecular weight:336.34

    Ref: TM-T3399