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Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.

Found 562 products of "Cyclooxygenase (COX) Inhibitors"

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  • 2,5-Di-tert-butylhydroquinone
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    2,5-Di-tert-butylhydroquinone

    CAS:
    <p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>
    Formula:C14H22O2
    Purity:97.11%
    Color and Shape:Pelletslargecrystals
    Molecular weight:222.32

    Ref: TM-T7540

  • (+)-Catechin Hydrate
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    (+)-Catechin Hydrate

    CAS:
    <p>(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological</p>
    Formula:C15H16O7
    Purity:99.03% - 99.96%
    Color and Shape:Solid
    Molecular weight:308.28

    Ref: TM-T2778

  • Chlorotrianisene
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    Chlorotrianisene

    CAS:
    <p>Chlorotrianisene, a synthetic SERM, is orally active, lipophilic, and has estrogenic and antiestrogenic effects.</p>
    Formula:C23H21ClO3
    Purity:98.88% - 99.03%
    Color and Shape:Crystals From Methanol Physical Description Small White Crystals Or White Powder Softens At 226°F Odorless (Ntp 1992)
    Molecular weight:380.86

    Ref: TM-T2569

  • Avicularin
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    Avicularin

    CAS:
    <p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>
    Formula:C20H18O11
    Purity:97.02% - 99.94%
    Color and Shape:White Powder
    Molecular weight:434.35

    Ref: TM-T6S0117

  • [8]-Shogaol
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    [8]-Shogaol

    CAS:
    <p>[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.</p>
    Formula:C19H28O3
    Purity:97.01%
    Color and Shape:Solid
    Molecular weight:304.42

    Ref: TM-T5430

  • Diclofenac Potassium
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    Diclofenac Potassium

    CAS:
    <p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>
    Formula:C14H10Cl2KNO2
    Purity:99.51%
    Color and Shape:White To Yellowish Crystalline Powder
    Molecular weight:334.24

    Ref: TM-T6470

  • Lumiracoxib
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    Lumiracoxib

    CAS:
    <p>Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.</p>
    Formula:C15H13ClFNO2
    Purity:96.64% - 99.77%
    Color and Shape:Pale Yellow Solid
    Molecular weight:293.72

    Ref: TM-T6574

  • (-)-Catechin gallate
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    (-)-Catechin gallate

    CAS:
    <p>(-)-Catechin gallate inhibits 6PGD, IDH, Beta-secretase, and fights chloroquine-sensitive/resistant Plasmodium falciparum.</p>
    Formula:C22H18O10
    Purity:97.74% - >99.99%
    Color and Shape:Solid
    Molecular weight:442.37

    Ref: TM-T3682

  • Adelmidrol
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    Adelmidrol

    CAS:
    <p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>
    Formula:C13H26N2O4
    Purity:99.35% - 99.73%
    Color and Shape:Solid
    Molecular weight:274.36

    Ref: TM-T3954

  • 7,3',4'-Tri-O-methylluteolin
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    7,3',4'-Tri-O-methylluteolin

    CAS:
    <p>7,3',4'-Tri-O-methylluteolin is anti-inflammatory, antibacterial, antifungal, and has moderate antitrypanosomal effects (MIC 19.0 ug/ml).</p>
    Formula:C18H16O6
    Purity:98.66% - 99.79%
    Color and Shape:Solid
    Molecular weight:328.32

    Ref: TM-TN1291

  • sphondin
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    sphondin

    CAS:
    <p>Sphondin inhibits IL-1beta, reduces COX-2 and PGE(2) in A549 cells, and has anticonvulsant, anti-inflammatory, anti-proliferative properties.</p>
    Formula:C12H8O4
    Purity:99.9% - ≥95%
    Color and Shape:Solid
    Molecular weight:216.19

    Ref: TM-T5758

  • Ginsenoside Rb3
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    Ginsenoside Rb3

    CAS:
    <p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>
    Formula:C53H90O22
    Purity:98% - 99.98%
    Color and Shape:Solid
    Molecular weight:1079.27

    Ref: TM-T3918

  • SC-58125
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    SC-58125

    CAS:
    <p>SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor. SC-58125 exhibits antitumor activity, and also inhibits oedema at sites of inflammation.</p>
    Formula:C17H12F4N2O2S
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:384.35

    Ref: TM-T23333

  • Roburic acid
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    Roburic acid

    CAS:
    <p>Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.</p>
    Formula:C30H48O2
    Purity:98.765% - 99.88%
    Color and Shape:Solid
    Molecular weight:440.7

    Ref: TM-T3883

  • Tinoridine
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    Tinoridine

    CAS:
    <p>Tinoridine is a quinoline derivative analog that acts by inhibiting the production of cyclooxygenase-2 (COX-2).</p>
    Formula:C17H20N2O2S
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:316.42

    Ref: TM-T50001

  • FK 3311
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    FK 3311

    CAS:
    <p>FK 3311 (COX-2 Inhibitor V) is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (</p>
    Formula:C15H13F2NO4S
    Purity:97.98%
    Color and Shape:Solid
    Molecular weight:341.33

    Ref: TM-T7207

  • Propyphenazone
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    Propyphenazone

    CAS:
    <p>Propyphenazone: an anti-inflammatory, analgesic, antipyretic pyrazolone; prodrug; COX-2 inhibitor.</p>
    Formula:C14H18N2O
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:230.31

    Ref: TM-T5010

  • Teriflunomide impurity 3
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    Teriflunomide impurity 3

    CAS:
    <p>Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor(IC50 of 30 μM).</p>
    Formula:C14H11F3N2O
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:280.25

    Ref: TM-T9042

  • Otenaproxesul
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    Otenaproxesul

    CAS:
    <p>Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.</p>
    Formula:C21H19NO3S
    Purity:98.76% - 99.13%
    Color and Shape:Solid
    Molecular weight:365.45

    Ref: TM-T1867

  • Fenoprofen Calcium
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    Fenoprofen Calcium

    CAS:
    <p>Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.</p>
    Formula:C30H26CaO6
    Purity:99.24% - 99.66%
    Color and Shape:Solid
    Molecular weight:522.6

    Ref: TM-T6497