GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 255 products of "GluR"
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Troriluzole
CAS:<p>Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.</p>Formula:C15H16F3N5O4SPurity:97.14%Color and Shape:SolidMolecular weight:419.38Dipraglurant
CAS:<p>Dipraglurant: a blood-brain permeable mGluR5 NAM, orally active, selective, IC50 = 21 nM, treats PD-LID.</p>Formula:C16H12FN3Purity:98.7%Color and Shape:SolidMolecular weight:265.29LSN2463359
CAS:<p>LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.</p>Formula:C16H15N3OPurity:99.26%Color and Shape:SolidMolecular weight:265.31(E/Z)-SIB-1893
CAS:<p>(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893.</p>Formula:C14H13NPurity:99.92%Color and Shape:SolidMolecular weight:195.26Dasolampanel
CAS:<p>Dasolampanel (NGX-426) is an ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders.</p>Formula:C17H20ClN5O3Purity:98.70%Color and Shape:SolidMolecular weight:377.83LY-2300559
CAS:<p>LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.</p>Formula:C26H26O6Purity:99.51%Color and Shape:SolidMolecular weight:434.48Valiglurax
CAS:<p>Valiglurax (VU2957), potent mGlu4 PAM, crosses blood-brain barrier, orally available; promising for Parkinson's treatment.</p>Formula:C16H10F3N5Purity:98.29%Color and Shape:SolidMolecular weight:329.28CBiPES hydrochloride
CAS:<p>CBiPES hydrochloride (CBiPES HCl) is an orthosteric modulator of the mGlu2 receptor and is used to study neurological disorders like epilepsy.</p>Formula:C21H20ClN3O2SPurity:99.66%Color and Shape:SolidMolecular weight:413.92CPCCOEt
CAS:<p>CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b</p>Formula:C13H13NO4Purity:99.91%Color and Shape:SolidMolecular weight:247.25S 18986
CAS:<p>S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in</p>Formula:C10H12N2O2SPurity:99.64%Color and Shape:SolidMolecular weight:224.28VU 0285683
CAS:<p>VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.</p>Formula:C14H7FN4OPurity:99.98%Color and Shape:SolidMolecular weight:266.23ABP688
CAS:<p>ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging.</p>Formula:C15H16N2OPurity:98.63%Color and Shape:SolidMolecular weight:240.3AZD 9272
CAS:<p>AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.</p>Formula:C14H6F2N4OPurity:98.29%Color and Shape:SolidMolecular weight:284.22AZD6538
CAS:<p>AZD6538 is an mGluR5 negative allosteric modulator used in the study of CNS-related diseases such as Alzheimer's disease.</p>Formula:C15H6FN5OPurity:98.68%Color and Shape:SolidMolecular weight:291.24MNI 137
CAS:<p>MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.</p>Formula:C15H9BrN4OPurity:97.49%Color and Shape:SolidMolecular weight:341.16VU0029251
CAS:<p>VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.</p>Formula:C10H11N3S2Color and Shape:SolidMolecular weight:237.34MTPG
CAS:<p>Group II/group III metabotropic glutamate receptor antagonist</p>Formula:C10H11N5O2Purity:98%Color and Shape:SolidMolecular weight:233.23L-AP4
CAS:<p>L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).</p>Formula:C4H10NO5PPurity:98%Color and Shape:White To Off-White Crystalline PowderMolecular weight:183.1mGluR5 antagonist-1
CAS:<p>mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].</p>Formula:C23H18N4O2Color and Shape:SolidMolecular weight:382.41VU0360172
CAS:<p>VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).</p>Formula:C18H15FN2OPurity:99.56%Color and Shape:SolidMolecular weight:294.32
