AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 574 products of "AChR"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
TC-T 6000
CAS:<p>TC-T 6000 (hENT4-IN-1) is an ENT4 inhibitor with vasodilator activity that inhibits hENT1 and hENT2 for the study of cancer and cardiovascular damage.</p>Formula:C26H48N8O2Purity:98.14%Color and Shape:SolidMolecular weight:504.71Tarafenacin D-tartrate
CAS:<p>Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.</p>Formula:C25H26F4N2O8Purity:99.86%Color and Shape:SolidMolecular weight:558.48SIB-1553A hydrochloride
CAS:<p>SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligand</p>Formula:C13H20ClNOSPurity:99.56% - 99.73%Color and Shape:SolidMolecular weight:273.82JNJ-39393406
CAS:<p>JNJ-39393406 is an α7 nicotinic acetylcholine receptor positive allosteric modulator for the study of tobacco dependence and Alzheimer's disease.</p>Formula:C19H18F2N6O3Purity:98.5%Color and Shape:SolidMolecular weight:416.38PHA 543613
CAS:<p>PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.</p>Formula:C15H17N3O2Purity:99.43% - 99.96%Color and Shape:SolidMolecular weight:271.31Thonzylamine hydrochloride
CAS:<p>Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.</p>Formula:C16H23ClN4OPurity:99.67%Color and Shape:White Crystalline PowderMolecular weight:322.83Desformylflustrabromine hydrochloride
CAS:<p>Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.</p>Formula:C17H12INO5Purity:98.12%Color and Shape:SolidMolecular weight:437.19AQW051
CAS:<p>AQW051 (VQW-765) is an oral α7-nAChR activator for cognitive impairments, used in anxiety disorder studies.</p>Formula:C19H22N2OPurity:99.94%Color and Shape:SolidMolecular weight:294.39PF-03635659
CAS:<p>PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.</p>Formula:C28H32N2O3Purity:98.39% - 99.83%Color and Shape:SolidMolecular weight:444.57rel-(1R,2R)-Vesamicol Hydrochloride
CAS:<p>Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.</p>Formula:C17H26ClNOPurity:99.88%Color and Shape:SolidMolecular weight:295.85SCH-900271
CAS:<p>SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.</p>Formula:C14H16N2O4Purity:98.82% - 99.93%Color and Shape:SolidMolecular weight:276.29CP-810123
CAS:<p>CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.</p>Formula:C14H18N4OPurity:98.63% - 99.60%Color and Shape:SolidMolecular weight:258.32McN-A 343
CAS:<p>McN-A 343: Selective M1 muscarinic agonist; reduces inflammation in colitis models.</p>Formula:C14H18Cl2N2O2Purity:99.65%Color and Shape:SolidMolecular weight:317.21Tribendimidine
CAS:<p>Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.</p>Formula:C28H32N6Purity:≥98%Color and Shape:SolidMolecular weight:452.59Xanomeline
CAS:<p>Xanomeline: orally active, M1/M4 selective activator for neurological disorders; promising in trials, crosses blood-brain barrier, liver metabolized.</p>Formula:C14H23N3OSPurity:99.61%Color and Shape:SolidMolecular weight:281.42Dimethindene
CAS:<p>Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.</p>Formula:C20H24N2Purity:98.3% - 98.99%Color and Shape:SolidMolecular weight:292.42ASM-024
CAS:<p>ASM-024, a synthetic piperazine, activates nicotinic and β2-adrenergic receptors for potential asthma and bronchitis treatment with anti-inflammatory effects.</p>Formula:C15H25N2Purity:99.74%Color and Shape:SolidMolecular weight:233.37Otenzepad
CAS:<p>Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.</p>Formula:C24H31N5O2Purity:99.79%Color and Shape:SolidMolecular weight:421.54NB001
CAS:<p>NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.</p>Formula:C12H20N6OPurity:99.69%Color and Shape:Off-White To Pale Pink SolidMolecular weight:264.33Xanomeline oxalate
CAS:<p>Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.</p>Formula:C16H25N3O5SPurity:99.1%Color and Shape:SolidMolecular weight:371.45
