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Tyrosine Kinase/Adaptors

Tyrosine Kinase/Adaptors

Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.

Subcategories of "Tyrosine Kinase/Adaptors"

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Found 1375 products of "Tyrosine Kinase/Adaptors"

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  • SGI-7079
    Targetmol
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    SGI-7079

    CAS:
    <p>SGI-7079: selective Axl inhibitor; hinders tumor growth dose-dependently; may target EGFR inhibitor resistance.</p>
    Formula:C26H26FN7
    Purity:95.51% - 99.26%
    Color and Shape:Solid
    Molecular weight:455.53

    Ref: TM-T6982

  • GIP (1-30) amide, porcine acetate
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    GIP (1-30) amide, porcine acetate

    <p>GIP (1-30) amide, porcine is a GIP receptor agonist that stimulates insulin and mildly inhibits gastric acid.</p>
    Formula:C164H249N41O49S
    Purity:98.50%
    Color and Shape:Solid
    Molecular weight:3611.04

    Ref: TM-T37588L

  • MAZ51
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    MAZ51

    CAS:
    <p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>
    Formula:C21H18N2O
    Purity:98.53%
    Color and Shape:Solid
    Molecular weight:314.38

    Ref: TM-T8496

  • PKI 14-22 amide, myristoylated Acetate
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    PKI 14-22 amide, myristoylated Acetate

    <p>PKI 14-22 amide, myristoylated Acetate inhibit cAMP-dependent protein kinase (PKA) and blocks hyperalgesia produced by spinal administration of 8-bromo-cAMP. </p>
    Formula:C55H104N20O14
    Purity:96.34%
    Color and Shape:Solid
    Molecular weight:1269.54

    Ref: TM-T21983L

  • G5-7
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    G5-7

    CAS:
    <p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>
    Formula:C22H19F2NO3
    Purity:97.3%
    Color and Shape:Solid
    Molecular weight:383.39

    Ref: TM-T8742

  • AZD8931 diFuMaric acid
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    AZD8931 diFuMaric acid

    CAS:
    <p>AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).</p>
    Formula:C31H33ClFN5O11
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:706.1

    Ref: TM-T8751

  • Theliatinib
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    Theliatinib

    CAS:
    <p>Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).</p>
    Formula:C25H26N6O2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:442.51

    Ref: TM-T7322

  • Theliatinib tartrate
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    Theliatinib tartrate

    CAS:
    <p>Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), &gt;50x kinase selectivity.</p>
    Formula:C29H32N6O8
    Color and Shape:Solid
    Molecular weight:592.6

    Ref: TM-T72431

  • UNC2025 2HCl (1429881-91-3(free base))
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    UNC2025 2HCl (1429881-91-3(free base))

    <p>UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.</p>
    Formula:C28H42Cl2N6O
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:549.62

    Ref: TM-T4419

  • Decernotinib
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    Decernotinib

    CAS:
    <p>Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.</p>
    Formula:C18H19F3N6O
    Purity:99.28% - >99.99%
    Color and Shape:Solid
    Molecular weight:392.38

    Ref: TM-T2636

  • RepSox
    Targetmol
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    RepSox

    CAS:
    <p>RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM).</p>
    Formula:C17H13N5
    Purity:98.8% - 99.73%
    Color and Shape:Solid
    Molecular weight:287.32

    Ref: TM-T6337

  • Malantide acetate(86555-35-3 free base)
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    Malantide acetate(86555-35-3 free base)

    <p>Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide</p>
    Formula:C74H128N22O23
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:1693.97

    Ref: TM-TP1789L

  • R112
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    R112

    CAS:
    <p>R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.</p>
    Formula:C16H13FN4O2
    Purity:99.27% - 99.84%
    Color and Shape:Solid
    Molecular weight:312.3

    Ref: TM-T3185

  • NRC-2694
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    NRC-2694

    CAS:
    <p>NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.</p>
    Formula:C24H26N4O3
    Purity:99.90%
    Color and Shape:Solid
    Molecular weight:418.49

    Ref: TM-T16343

  • SYR127063
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    SYR127063

    CAS:
    <p>SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.</p>
    Formula:C23H20ClF3N4O3
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:492.88

    Ref: TM-T34760

  • Ponatinib
    Targetmol
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    Ponatinib

    CAS:
    <p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>
    Formula:C29H27F3N6O
    Purity:98% - 99.60%
    Color and Shape:Solid
    Molecular weight:532.56

    Ref: TM-T2372

  • PQ401 hydrochloride (196868-63-0(free base))
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    PQ401 hydrochloride (196868-63-0(free base))

    <p>PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of &lt;1 μM.</p>
    Formula:C18H17Cl2N3O2
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:378.25

    Ref: TM-T4324

  • Oritinib mesylate
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    Oritinib mesylate

    CAS:
    <p>Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.</p>
    Formula:C32H41N7O5S
    Color and Shape:Solid
    Molecular weight:635.78

    Ref: TM-T39670

  • R-268712
    Targetmol
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    R-268712

    CAS:
    <p>R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type I receptor orally.</p>
    Formula:C20H18FN5O
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:363.39

    Ref: TM-T16708

  • MSDC 0160
    Targetmol
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    MSDC 0160

    CAS:
    <p>MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.</p>
    Formula:C19H18N2O4S
    Purity:98.11% - 99.53%
    Color and Shape:Solid
    Molecular weight:370.42

    Ref: TM-T2607