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Tyrosine Kinase/Adaptors

Tyrosine Kinase/Adaptors

Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.

Subcategories of "Tyrosine Kinase/Adaptors"

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Found 1375 products of "Tyrosine Kinase/Adaptors"

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  • RO9021
    Targetmol
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    RO9021

    CAS:
    <p>RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).</p>
    Formula:C18H25N7O
    Purity:97.19%
    Color and Shape:Solid
    Molecular weight:355.44

    Ref: TM-T16776

  • EGFR/HER2-IN-3
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    EGFR/HER2-IN-3

    CAS:
    <p>EGFR/HER2-IN-3 (Compound ZINC21942954) is a dual EGFR and HER2 inhibitor.</p>
    Formula:C26H23N5O3
    Color and Shape:Solid
    Molecular weight:453.49

    Ref: TM-T62777

  • Protein kinase inhibitor 5
    Targetmol
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    Protein kinase inhibitor 5

    CAS:
    <p>Protein kinase inhibitor 5 is a potent inhibitor of TRK-A, demonstrating an IC50 of 1.8 nM, and effectively suppresses cell viability [1].</p>
    Formula:C29H31F2N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:531.6

    Ref: TM-T79125

  • NSC114126
    Targetmol
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    NSC114126

    CAS:
    <p>NSC114126 is a potent, oral EGFR-TK inhibitor with strong antiproliferative effects, promising for cancer research.</p>
    Formula:C22H20O4
    Color and Shape:Solid
    Molecular weight:348.39

    Ref: TM-T61177

  • EGFR-IN-54
    Targetmol
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    EGFR-IN-54

    CAS:
    <p>EGFR-IN-54 (Compound 3c) is a potent inhibitor of EGFR (IC50: 1.623 μM) and is toxic to cancer cells.</p>
    Formula:C17H14N4O4S3
    Color and Shape:Solid
    Molecular weight:434.51

    Ref: TM-T62457

  • EGFR-IN-50
    Targetmol
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    EGFR-IN-50

    CAS:
    <p>EGFR-IN-50, a potent EGFR blocker, hinders L858R mutation; GI50: 8 nM for TEL-EGFR-L858R, 6.03 μM for T790M-L858R; curbs cancer cell growth.</p>
    Formula:C24H26BrN3O4S2
    Color and Shape:Solid
    Molecular weight:564.51

    Ref: TM-T63996

  • EGFR-IN-25
    Targetmol
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    EGFR-IN-25

    CAS:
    <p>EGFR-IN-25, an efficacious EGFR inhibitor, demonstrates IC50 values of 9 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and 60 nM for A431 cells (WT), respectively.</p>
    Formula:C34H43N9O2
    Color and Shape:Solid
    Molecular weight:609.76

    Ref: TM-T73101

  • CHMFL-BTK-01
    Targetmol
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    CHMFL-BTK-01

    CAS:
    <p>CHMFL-BTK-01 is an irreversible inhibitor of BTK (IC50: 7 nM) and also potently inhibits BTK Y223 auto-phosphorylation.</p>
    Formula:C38H41N5O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:647.76

    Ref: TM-T14956

  • FGFR2-IN-1
    Targetmol
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    FGFR2-IN-1

    CAS:
    <p>FGFR2-IN-1 is an FGFR inhibitor that inhibits FGFR1, FGFR2, and FGFR3, and can be used to study FGFR2-associated cancers.</p>
    Formula:C22H19N3O2
    Purity:98.71%
    Color and Shape:Solid
    Molecular weight:357.41

    Ref: TM-T61304

  • JBJ-09-063 hydrochloride
    Targetmol
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    JBJ-09-063 hydrochloride

    <p>JBJ-09-063 hydrochloride: targeted EGFR inhibitor, effective for various mutations and TKI-resistant lung cancer models.</p>
    Formula:C31H30ClFN4O3S
    Color and Shape:Solid
    Molecular weight:593.11

    Ref: TM-T72237

  • AG-183
    Targetmol
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    AG-183

    CAS:
    <p>(Z)-Tyrphostin A51, a Z-isomer of Lanoconazole A51, is a strong PTK inhibitor blocking [3 H]taurine release and tyrosyl phosphorylation.</p>
    Formula:C13H8N4O3
    Color and Shape:Brown Solid
    Molecular weight:268.23

    Ref: TM-T21783

  • TC-S 7003
    Targetmol
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    TC-S 7003

    CAS:
    <p>TC-S 7003 (Lck Inhibitor) is a Lck inhibitor with anti-inflammatory activity that inhibits T-cell proliferation and can be used to study arthritis.</p>
    Formula:C31H30N8O
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:530.62

    Ref: TM-T15726

  • EGFR/HER2-IN-2
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    EGFR/HER2-IN-2

    CAS:
    <p>EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual EGFR and HER2 inhibitor that acts on both EGFR (IC50: 5.02 μM) and HER2 (IC50: 0.83 μM).</p>
    Formula:C26H23N5O3
    Color and Shape:Solid
    Molecular weight:453.49

    Ref: TM-T62776

  • Nimotuzumab
    Targetmol
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    Nimotuzumab

    CAS:
    <p>Nimotuzumab is a humanized therapeutic monoclonal antibody against epidermal growth factor receptor EGFR).</p>
    Purity:95.00% - 98.5% (SDS-PAGE); 96.4% (SEC-HPLC)
    Color and Shape:Liquid

    Ref: TM-T9923

  • c-Fms-IN-6
    Targetmol
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    c-Fms-IN-6

    CAS:
    <p>c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: &gt; 1 μM).</p>
    Formula:C22H25N7O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:419.48

    Ref: TM-T10645

  • CSF1R-IN-7
    Targetmol
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    CSF1R-IN-7

    CAS:
    <p>CSF1R-IN-7 is a highly selective CSF-1R inhibitor with good brain penetration for treatment of diseases associated with microglia-mediated neuroinflammation.</p>
    Formula:C22H22N6O3
    Purity:99.41% - 99.93%
    Color and Shape:Solid
    Molecular weight:418.45

    Ref: TM-T62190

  • EGFR-IN-73
    Targetmol
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    EGFR-IN-73

    CAS:
    <p>EGFR-IN-73 (Compound 3f) effectively inhibits the prevalent EGFR mutation, EGFR Del19, exhibiting an IC50 value of 119 nM [1].</p>
    Formula:C19H17ClFN3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:405.81

    Ref: TM-T73165

  • (R)-Zanubrutinib
    Targetmol
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    (R)-Zanubrutinib

    CAS:
    <p>(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).</p>
    Formula:C27H29N5O3
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:471.55

    Ref: TM-T13447

  • AMPK-IN-3
    Targetmol
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    AMPK-IN-3

    CAS:
    <p>AMPK-IN-3: potent, selective AMPK (α2/α1) &amp; KDR inhibitor; IC50: 60.7/107/3820 nM; anticancer in K562 cells.</p>
    Formula:C25H33N5O3
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:451.56

    Ref: TM-T62745

  • SKLB 1028
    Targetmol
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    SKLB 1028

    CAS:
    <p>SKLB 1028, an oral EGFR/FLT3/Abl inhibitor, excels in AML and CML with Abl mutations.</p>
    Formula:C24H29N9
    Purity:99.90% - >99.99%
    Color and Shape:Solid
    Molecular weight:443.55

    Ref: TM-T34656

  • I-OMe-Tyrphostin AG 538
    Targetmol
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    I-OMe-Tyrphostin AG 538

    CAS:
    <p>I-OMe-Tyrphostin AG 538: IGF-1R &amp; PI5P4Kα inhibitor, ATP-competitive, IC50 of 1 µM, targets IGF-1R pathway, cytotoxic in nutrient-poor PANC1 cells.</p>
    Formula:C17H12INO5
    Purity:98.23%
    Color and Shape:Solid
    Molecular weight:437.19

    Ref: TM-T11593

  • Chiauranib
    Targetmol
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    Chiauranib

    CAS:
    <p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>
    Formula:C27H21N3O3
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:435.47

    Ref: TM-T35570

  • EGFR-IN-99
    Targetmol
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    EGFR-IN-99

    CAS:
    <p>EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor for the study of non-small cell lung cancer (NSCLC).</p>
    Formula:C25H22FN7O3
    Purity:97.75%
    Color and Shape:Solid
    Molecular weight:487.49

    Ref: TM-T35901

  • CGP77675
    Targetmol
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    CGP77675

    CAS:
    <p>CGP77675 (ZINC1488120) is a potent and selective inhibitor of Src family kinase with IC50s of 5-20 and 40 nM for the phosphorylation of peptide substrates and</p>
    Formula:C26H29N5O2
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:443.54

    Ref: TM-T30855

  • INDY
    Targetmol
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    INDY

    CAS:
    <p>INDY is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B with IC50s of 0.24 μM and 0.23 μM and a Ki of 0.18 μM for Dyrk1A ATP pocket, respectively.</p>
    Formula:C12H13NO2S
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:235.3

    Ref: TM-T15579

  • (Z)-FeCP-oxindole
    Targetmol
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    (Z)-FeCP-oxindole

    CAS:
    <p>(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.</p>
    Formula:C19H15FeNO
    Purity:99.63% - 99.84%
    Color and Shape:Solid
    Molecular weight:329.17

    Ref: TM-T23554

  • CLK-IN-T3
    Targetmol
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    CLK-IN-T3

    CAS:
    <p>CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.</p>
    Formula:C28H30N6O2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:482.58

    Ref: TM-T14980

  • Pz-1
    Targetmol
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    Pz-1

    CAS:
    <p>Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.</p>
    Formula:C26H26N6O2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:454.52

    Ref: TM-T12598

  • SU16f
    Targetmol
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    SU16f

    CAS:
    <p>SU16f, a 3-substituted indolin-2-one, is a selective PDGFRβ inhibitor; IC50: 10 nM (PDGFRβ), 140 nM (PDGFR1), 2.29 μM (PDGFR2), halts GC cell growth.</p>
    Formula:C24H22N2O3
    Purity:97.69%
    Color and Shape:Solid
    Molecular weight:386.44

    Ref: TM-T16947

  • DDR Inhibitor
    Targetmol
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    DDR Inhibitor

    CAS:
    <p>DDR inhibitor is a potent discidin domain receptor (DDR) inhibitor. The IC50 of DDR2 is 3.3 nM, and DDR1 has 53% inhibition at 1.5 nM.</p>
    Formula:C23H20FN5O2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:417.44

    Ref: TM-T10985

  • Larotinib
    Targetmol
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    Larotinib

    CAS:
    <p>Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.</p>
    Formula:C24H26ClFN4O4
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:488.94

    Ref: TM-T73334

  • GTP-14564
    Targetmol
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    GTP-14564

    CAS:
    <p>GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.</p>
    Formula:C15H10N2O
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:234.25

    Ref: TM-T71857

  • (E)-FeCP-oxindole
    Targetmol
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    (E)-FeCP-oxindole

    CAS:
    <p>(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂，IC50 为 214 nM。</p>
    Formula:C19H15FeNO
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:329.17

    Ref: TM-T22755

  • Pimicotinib
    Targetmol
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    Pimicotinib

    CAS:
    <p>Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.</p>
    Formula:C22H24N6O3
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:420.46

    Ref: TM-T79157

  • VEGFR-3-IN-1
    Targetmol
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    VEGFR-3-IN-1

    CAS:
    <p>VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.</p>
    Formula:C29H29ClF3N7OS
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:616.1

    Ref: TM-T72924

  • PD 174265
    Targetmol
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    PD 174265

    CAS:
    <p>PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.</p>
    Formula:C17H15BrN4O
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:371.23

    Ref: TM-T28339

  • Epitinib succinate
    Targetmol
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    Epitinib succinate

    CAS:
    <p>Epitinib succinate (HMPL-813 succinate) is an orally active and brain penetration EGFR tyrosine kinase inhibitor and can be used in studies about cancer.</p>
    Formula:C28H32N6O6
    Purity:98.02% - 99.79%
    Color and Shape:Solid
    Molecular weight:548.59

    Ref: TM-T35914

  • Cloperastine fendizoate
    Targetmol
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    Cloperastine fendizoate

    CAS:
    <p>Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).</p>
    Formula:C40H38ClNO5
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:648.19

    Ref: TM-T13619

  • YK-2-69
    Targetmol
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    YK-2-69

    CAS:
    <p>YK-2-69 selectively blocks DYRK2 at Lys-231 and Lys-234, outperforming enzalutamide in prostate cancer treatment.</p>
    Formula:C25H27FN8OS
    Purity:98.61% - 99.64%
    Color and Shape:Solid
    Molecular weight:506.6

    Ref: TM-T69564

  • ProINDY
    Targetmol
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    ProINDY

    CAS:
    <p>ProINDY (Pro-indy) is a potent DYRK inhibitor that activates NFAT for the study of Down syndrome.</p>
    Formula:C14H15NO3S
    Purity:97.19%
    Color and Shape:Solid
    Molecular weight:277.34

    Ref: TM-T23186

  • (±)-Zanubrutinib
    Targetmol
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    (±)-Zanubrutinib

    CAS:
    <p>(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability,</p>
    Formula:C27H29N5O3
    Purity:99.09%
    Color and Shape:Solid
    Molecular weight:471.55

    Ref: TM-TQ0039

  • A 419259 trihydrochloride
    Targetmol
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    A 419259 trihydrochloride

    CAS:
    <p>A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).</p>
    Formula:C29H37Cl3N6O
    Purity:99.75% - 99.96%
    Color and Shape:Solid
    Molecular weight:592

    Ref: TM-TQ0132

  • Tilfrinib
    Targetmol
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    Tilfrinib

    CAS:
    <p>Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities.</p>
    Formula:C17H13N3O
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:275.3

    Ref: TM-T17098

  • ML 315
    Targetmol
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    ML 315

    CAS:
    <p>ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.</p>
    Formula:C18H13Cl2N3O2
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:374.22

    Ref: TM-T36707

  • Rezivertinib
    Targetmol
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    Rezivertinib

    CAS:
    <p>Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study central nervous system diseases.</p>
    Formula:C27H30N6O3
    Purity:99.26% - 99.89%
    Color and Shape:Solid
    Molecular weight:486.57

    Ref: TM-T36644

  • Falnidamol
    Targetmol
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    Falnidamol

    CAS:
    <p>Falnidamol (BIBX 1382), an oral selective EGFR inhibitor, IC50 3 nM, weak on ErbB2 and others, anti-cancer pyrimido-pyrimidine.</p>
    Formula:C18H19ClFN7
    Purity:98.816%
    Color and Shape:Solid
    Molecular weight:387.84

    Ref: TM-TQ0271

  • PP58
    Targetmol
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    PP58

    CAS:
    <p>PP58 is an inhibitor of PDGFR, FGFR and Src family.</p>
    Formula:C22H19Cl2N5O2
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:456.32

    Ref: TM-T13824

  • LY 456236 hydrochloride
    Targetmol
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    LY 456236 hydrochloride

    CAS:
    <p>LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM.</p>
    Formula:C16H16ClN3O2
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:317.77

    Ref: TM-T22954

  • TG-89
    Targetmol
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    TG-89

    CAS:
    <p>TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 μM against JAK2, showing anticancer activity in the treatment of ovarian and</p>
    Formula:C26H34N6O3S
    Purity:98.68%
    Color and Shape:Solid
    Molecular weight:510.65

    Ref: TM-T20742

  • Sunvozertinib
    Targetmol
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    Sunvozertinib

    CAS:
    <p>Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor, with inhibitory effects on EGFR, Her2.Cost-effective and quality-assured.</p>
    Formula:C29H35ClFN7O3
    Purity:98.11% - 99.63%
    Color and Shape:Solid
    Molecular weight:584.08

    Ref: TM-T64124