Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
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Subcategories of "Tyrosine Kinase/Adaptors"
ALK
CSF-1R
EGFR
Ephrin Receptor
FLT
Fibroblast Growth Factor Receptor (FGFR)
HER
Hck
IGF-1R
PDGFR
PYK2
Src
TAM Receptor
Tie-2
Trk receptor
Tyrosine Kinases
VEGFR
c-Fms
c-Kit
c-Met/HGFR
c-RET
Show 13 more subcategories
Products of "Tyrosine Kinase/Adaptors"
Cetuximab MMAE
Cetuximab-MMAE, an antibody-drug conjugate (ADC), combines an EGFR-targeting antibody with Monomethyl auristatin E (MMAE) to …
Color and Shape:
Liquid
Molecular weight:
150 kDa
Ref: TM-T9901A-219
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 16 Dec 2024
Mecbotamab vedotin
CAS:2460400-64-8
Mecbotamab vedotin (BA301) is an inhibitory IgG1 antibody that targets human tyrosine kinase receptor AXL …
Color and Shape:
Liquid
Ref: TM-T9901A-225
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 16 Dec 2024
EGFR-IN-124
EGFR-IN-124 (compound 10A) is an EGFR inhibitor with an IC50 value of 0.54 μM, utilized …
Ref: TM-T200720
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 16 Dec 2024
EGFR-IN-127
EGFR-IN-127 is an ATP-competitive inhibitor targeting EGFR, with IC50 values of 136.3 nM for EGFRdel19 …
Ref: TM-T200430
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 16 Dec 2024
NBI-31772
CAS:374620-70-9
NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki …
Formula:
C17H11NO7
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
341.27
Ref: TM-T8906
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 154.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 504.00 € | ||
| 100mg | 722.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Kemptide
CAS:65189-71-1
Kemptide is a synthetic heptapeptide, acting as a substrate for cAMP-dependent protein kinase (PK).
Formula:
C32H61N13O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
771.91
Ref: TM-TP1351
| 1mg | 108.00 € | ||
| 5mg | 332.00 € | ||
| 10mg | 610.00 € | ||
| 25mg | 1,385.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
BI-4732
CAS:2769715-68-4
DL-Homocystine is a mutagen secreted by F. nucleatum.
Formula:
C32H36N10O2
Color and Shape:
Liquid
Molecular weight:
592.69
Ref: TM-T85354
| 1mg | 380.00 € | ||
| 5mg | 828.00 € | ||
| 10mg | 1,110.00 € | ||
| 25mg | 1,597.00 € | ||
| 50mg | 2,159.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Necitumumab
Necitumumab (IMC-11F8) is a human monoclonal antibody against EGFR, an anti-angiogenic agent used in the …
Color and Shape:
Liquid
Molecular weight:
145.5 kDa
Ref: TM-T77459
| 1mg | 186.00 € | ||
| 5mg | 554.00 € | ||
| 10mg | 880.00 € | ||
| 25mg | 1,298.00 € | ||
| 50mg | 1,698.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Cixutumumab
CAS:947687-12-9
Cixutumumab (IMC-A12), a humanized monoclonal antibody targeting IGF-1R, exhibits high affinity and inhibits ligand-dependent receptor …
Purity:
95% - 95%
Color and Shape:
Liquid
Ref: TM-T78279
| 1mg | 117.00 € | ||
| 5mg | 314.00 € | ||
| 10mg | 505.00 € | ||
| 25mg | 805.00 € | ||
| 50mg | 1,079.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
ARRY-380 (analog )
CAS:937265-83-3
ARRY-380 analog (HER2-Inhibitor-1) is a potent and selective HER2 inhibitor.
Formula:
C29H27N7O4S
Purity:
98.22%
Color and Shape:
Solid
Molecular weight:
569.63
Ref: TM-T2518
| 1mg | 35.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 108.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 261.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
WAY-270250
CAS:852367-46-5
WAY-270250 is an IGF-1R/SRC inhibitor.
Formula:
C18H16N2O2
Purity:
99.77%
Color and Shape:
Soild
Molecular weight:
292.33
Ref: TM-T77624
| 1mg | 37.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 199.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 442.00 € | ||
| 500mg | 997.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Disitamab vedotin
CAS:2136633-23-1
Disitamab vedotin (RC-48) is a HER2-targeting ADC with MMAE, effective in HER2-expressing gastric cancer.
Purity:
95.00% - 98%
Color and Shape:
Liquid
Molecular weight:
Approximately 144.15 kDa
Ref: TM-T39595
| 1mg | 324.00 € | ||
| 5mg | 783.00 € | ||
| 10mg | 1,083.00 € | ||
| 25mg | 1,606.00 € | ||
| 50mg | 2,166.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
PF-04217903 phenolsulfonate
CAS:1159490-85-3
PF-04217903 phenolsulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for …
Formula:
C25H22N8O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
546.56
Ref: TM-T12418
| 25mg | 1,432.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Acrizanib
CAS:1229453-99-9
Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2.
Formula:
C20H18F3N7O2
Purity:
98.71% - 98.72%
Color and Shape:
Solid
Molecular weight:
445.4
Ref: TM-T5373
| 1mg | 109.00 € | ||
| 5mg | 269.00 € | ||
| 10mg | 414.00 € | ||
| 25mg | 707.00 € | ||
| 50mg | 984.00 € | ||
| 100mg | 1,281.00 € | ||
| 1mL*10mM (DMSO) | 295.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Pertuzumab
CAS:380610-27-5
Pertuzumab (anti-HER2) a humanized monoclonal antibody and the first in the class of agents called …
Purity:
98.00%
Color and Shape:
Liquid
Molecular weight:
148 kDa
Ref: TM-T9909
| 1mg | 177.00 € | ||
| 5mg | 537.00 € | ||
| 10mg | 773.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Taletrectinib free base
CAS:1505514-27-1
Taletrectinib (AB-106) is a potent, selective oral ROS1/NTRK inhibitor with low IC50s against ROS1 and …
Formula:
C23H24FN5O
Purity:
99.87%
Color and Shape:
Liquid
Molecular weight:
405.47
Ref: TM-T38995
| 1mg | 70.00 € | ||
| 5mg | 153.00 € | ||
| 10mg | 238.00 € | ||
| 25mg | 480.00 € | ||
| 50mg | 690.00 € | ||
| 100mg | 975.00 € | ||
| 1mL*10mM (DMSO) | 182.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
GIP (3-42), human
CAS:1802086-25-4
Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes …
Formula:
C214H324N58O63S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
4749.35
Ref: TM-T37589
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 656.00 € | ||
| 25mg | 1,027.00 € | ||
| 50mg | 1,403.00 € | ||
| 100mg | 1,865.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Mutated EGFR-IN-3
CAS:2375107-27-8
Mutated EGFR-IN-3: ATP-competitive, selective dibenzodiazepinone inhibitor for EGFR mutations, IC50 12-13 nM.
Formula:
C31H29FN4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
508.59
Ref: TM-T12131
| 25mg | 1,435.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Varlitinib
CAS:845272-21-1
Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, …
Formula:
C22H19ClN6O2S
Purity:
99.7%
Color and Shape:
Solid
Molecular weight:
466.94
Ref: TM-T6719
| 1mg | 35.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 165.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
KN1022
CAS:205255-11-4
KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of …
Formula:
C21H22N6O5
Purity:
99.88%
Color and Shape:
Soild
Molecular weight:
438.44
Ref: TM-T60110
| 1mg | 113.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 366.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 769.00 € | ||
| 100mg | 1,049.00 € | ||
| 500mg | 2,098.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
