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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1424 products of "Autophagy"

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  • Sanguinarine

    CAS:
    <p>Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.</p>
    Formula:C20H14NO4
    Purity:99.04% - 99.76%
    Color and Shape:Solid
    Molecular weight:332.33
  • TFEB activator 1

    CAS:
    <p>TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer's</p>
    Formula:C19H18O3
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:294.34
  • Isorhapontigenin

    CAS:
    <p>Isorhapontigenin: a methoxylated stilbenoid isomer of rhapontigenin, similar to resveratrol, present in Gnetum spp. and Aiphanes aculeata seeds.</p>
    Formula:C15H14O4
    Purity:98.49% - 99.85%
    Color and Shape:Off White Crystals Power
    Molecular weight:258.27
  • PTC-209

    CAS:
    <p>PTC-209 is a potent and selective BMI-1 inhibitor.</p>
    Formula:C17H13Br2N5OS
    Purity:99.43% - 99.887%
    Color and Shape:Solid
    Molecular weight:495.19
  • Lys05

    CAS:
    <p>Lys05, a potent autophagy inhibitor, outperforms HCQ in cancer treatment, showing promise for drug development.</p>
    Formula:C23H26Cl5N5
    Purity:99.13% - 99.55%
    Color and Shape:Solid
    Molecular weight:549.75
  • Valproic Acid

    CAS:
    <p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>
    Formula:C8H16O2
    Purity:97.78% - 99%
    Color and Shape:Colourless To Pale Yellow Liquid Viscous
    Molecular weight:144.21
  • Polydatin

    CAS:
    <p>Polydatin, a resveratrol glycoside from Polygonum cuspidatum, inhibits platelet aggregation, alters lipid ratios, and modulates cell functions.</p>
    Formula:C20H22O8
    Purity:97.2% - 98.94%
    Color and Shape:White Fine Powder
    Molecular weight:390.38
  • Rac-Belinostat

    CAS:
    <p>Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.</p>
    Formula:C15H14N2O4S
    Purity:99.67% - 99.96%
    Color and Shape:Solid
    Molecular weight:318.35
  • S29434

    CAS:
    <p>S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).</p>
    Formula:C21H18N4O3
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:374.39
  • Momelotinib

    CAS:
    <p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>
    Formula:C23H22N6O2
    Purity:97.47% - 99.56%
    Color and Shape:Solid
    Molecular weight:414.46
  • PH-797804

    CAS:
    <p>PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.</p>
    Formula:C22H19BrF2N2O3
    Purity:97.90% - 98.27%
    Color and Shape:Solid
    Molecular weight:477.3
  • Cordycepin

    CAS:
    <p>Cordycepin (3'-Deoxyadenosine) is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic</p>
    Formula:C10H13N5O3
    Purity:99.87% - >99.99%
    Color and Shape:Crystalline Solid
    Molecular weight:251.24
  • Deoxypodophyllotoxin

    CAS:
    <p>Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.</p>
    Formula:C22H22O7
    Purity:99.65% - 99.84%
    Color and Shape:Solid
    Molecular weight:398.41
  • Piperlongumine

    CAS:
    <p>Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.</p>
    Formula:C17H19NO5
    Purity:97.03% - 99.90%
    Color and Shape:Solid
    Molecular weight:317.34
  • Elubrixin HCl

    CAS:
    <p>Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist.</p>
    Formula:C17H18Cl3FN4O4S
    Color and Shape:Solid
    Molecular weight:499.77
  • SNX2112

    CAS:
    <p>SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM.</p>
    Formula:C23H27F3N4O3
    Purity:98.75% - 99.46%
    Color and Shape:Solid
    Molecular weight:464.48
  • Isradipine

    CAS:
    <p>Isradipine (PN 200-110), a dihydropyridine, is an antihypertensive calcium channel blocker that dilates arteries and reduces resistance.</p>
    Formula:C19H21N3O5
    Purity:99.84% - 99.95%
    Color and Shape:Yellow Solid
    Molecular weight:371.39
  • Selenomethionine

    CAS:
    <p>DL-Selenomethionine (SeMet) is a selenium analog of methionine, substituting sulfur with selenium, and can replace methionine in proteins.</p>
    Formula:C5H11NO2Se
    Purity:98% - 99.95%
    Color and Shape:Transparent Hexagonal Sheets Or Plates; Metallic Luster Of Crystals Solid
    Molecular weight:196.11
  • AM580

    CAS:
    <p>AM580 (CD336) is a retinoic acid receptor agonist that is selective for RARα( IC50 : 8 nM )</p>
    Formula:C22H25NO3
    Purity:98% - 99.89%
    Color and Shape:Solid
    Molecular weight:351.44
  • Mavorixafor trihydrochloride

    CAS:
    <p>Mavorixafor trihydrochloride blocks CXCR4 (IC50: 13 nM) and suppresses T-tropic HIV-1 replication (IC50: 1-9 nM). It's orally active.</p>
    Formula:C21H30Cl3N5
    Purity:98.00%
    Color and Shape:Solid
    Molecular weight:458.86
  • Bakuchiol

    CAS:
    <p>Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.</p>
    Formula:C18H24O
    Purity:98.04% - 99.05%
    Color and Shape:Brownish Yellow Liquid Viscous
    Molecular weight:256.38
  • Enalaprilat Dihydrate

    CAS:
    <p>Enalaprilat Dihydrate (MK-422 Dihydrate) (IC50=1.94 nM) is a potent angiotensin-converting enzyme (ACE) inhibitor.</p>
    Formula:C18H24N2O5·2H2O
    Purity:99.46% - 99.78%
    Color and Shape:Solid
    Molecular weight:348.4
  • GNE0877

    CAS:
    <p>GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).</p>
    Formula:C14H16F3N7
    Purity:98.01% - 99.97%
    Color and Shape:Solid
    Molecular weight:339.32
  • Reversine

    CAS:
    <p>Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).</p>
    Formula:C21H27N7O
    Purity:98% - 98.42%
    Color and Shape:Solid
    Molecular weight:393.49
  • ABT-751

    CAS:
    <p>ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.</p>
    Formula:C18H17N3O4S
    Purity:98.84% - 99.50%
    Color and Shape:Solid
    Molecular weight:371.41
  • IKK 16

    CAS:
    <p>IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.</p>
    Formula:C28H29N5OS
    Purity:98.76% - 99.61%
    Color and Shape:Solid
    Molecular weight:483.63
  • Apigenin

    CAS:
    <p>Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants.</p>
    Formula:C15H10O5
    Purity:97.64% - 99.66%
    Color and Shape:Yellow Needles From Aqueous Pyridine Solid
    Molecular weight:270.24
  • A-867744

    CAS:
    <p>A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).</p>
    Formula:C20H19ClN2O3S
    Purity:95.66%
    Color and Shape:Solid
    Molecular weight:402.89
  • NL-1

    CAS:
    <p>NL-1 is a mitoNEET inhibitor with antileukemic effect.</p>
    Formula:C18H25NO3S
    Purity:98.64%
    Color and Shape:Solid
    Molecular weight:335.46
  • JH-II-127

    CAS:
    <p>JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).</p>
    Formula:C19H21ClN6O3
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:416.86
  • Ruxolitinib

    CAS:
    <p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>
    Formula:C17H18N6
    Purity:99.4% - >99.99%
    Color and Shape:Solid
    Molecular weight:306.36
  • Corynoxine

    CAS:
    <p>Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.</p>
    Formula:C22H28N2O4
    Purity:96.83% - 99.93%
    Color and Shape:Solid
    Molecular weight:384.47
  • Silibinin

    CAS:
    <p>Silibinin, main component in milk thistle, offers liver protection and shows anti-cancer potential in various human cells.</p>
    Formula:C25H22O10
    Purity:97.98% - 98.37%
    Color and Shape:Solid
    Molecular weight:482.44
  • CHIR-99021

    CAS:
    <p>View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.</p>
    Formula:C22H18Cl2N8
    Purity:97.94% - ≥95%
    Color and Shape:Solid
    Molecular weight:465.34
  • TWS119

    CAS:
    <p>TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation</p>
    Formula:C18H14N4O2
    Purity:98.14% - 99.63%
    Color and Shape:Solid
    Molecular weight:318.33
  • α-Thujone

    CAS:
    <p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>
    Formula:C10H16O
    Purity:97.02% - 98.41%
    Color and Shape:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)
    Molecular weight:152.23
  • Urolithin A

    CAS:
    <p>Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.</p>
    Formula:C13H8O4
    Purity:99.14% - 99.67%
    Color and Shape:Solid
    Molecular weight:228.2
  • Rutin hydrate

    CAS:
    <p>Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.</p>
    Formula:C27H32O17
    Purity:97.23%
    Color and Shape:Solid
    Molecular weight:628.53
  • Liensinine diperchlorate

    CAS:
    <p>Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus.</p>
    Formula:C37H44Cl2N2O14
    Purity:99.8% - ≥95%
    Color and Shape:Solid
    Molecular weight:811.67
  • Bafilomycin A1

    CAS:
    <p>Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.</p>
    Formula:C35H58O9
    Purity:95.87% - 99.36%
    Color and Shape:Solid
    Molecular weight:622.83
  • Belinostat

    CAS:
    <p>Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.</p>
    Formula:C15H14N2O4S
    Purity:99.75% - >99.99%
    Color and Shape:Solid
    Molecular weight:318.35
  • Entrectinib

    CAS:
    <p>Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.</p>
    Formula:C31H34F2N6O2
    Purity:98.03% - 99.61%
    Color and Shape:Solid
    Molecular weight:560.64
  • Quercetin

    CAS:
    <p>Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.</p>
    Formula:C15H10O7
    Purity:96.29% - 98.05%
    Color and Shape:Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)
    Molecular weight:302.24
  • Quisinostat

    CAS:
    <p>Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.</p>
    Formula:C21H26N6O2
    Purity:96.01% - ≥98%
    Color and Shape:Solid
    Molecular weight:394.47
  • Dronedarone

    CAS:
    <p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>
    Formula:C31H44N2O5S
    Purity:98.85% - 99.58%
    Color and Shape:Solid
    Molecular weight:556.76
  • PF-04457845

    CAS:
    <p>PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).</p>
    Formula:C23H20F3N5O2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:455.43
  • MRT68921

    CAS:
    <p>MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.</p>
    Formula:C25H34N6O
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:434.58
  • KU-55933

    CAS:
    <p>KU-55933 (ATM Kinase Inhibitor) is an ATM inhibitor that is selective and ATP-competitive. KU-55933 has antitumor effects. Cost-effective and quality-assured.</p>
    Formula:C21H17NO3S2
    Purity:97.21% - >99.99%
    Color and Shape:Solid
    Molecular weight:395.49
  • CGI-1746

    CAS:
    <p>CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.</p>
    Formula:C34H37N5O4
    Purity:97.69% - 97.88%
    Color and Shape:Solid
    Molecular weight:579.69
  • Tolvaptan

    CAS:
    <p>Tolvaptan (OPC-41061) is an orally bioavailable, selective, arginine vasopressin receptor 2 (V2, AVPR2) antagonist that can be used to treat hyponatremia.</p>
    Formula:C26H25ClN2O3
    Purity:99.78% - >99.99%
    Color and Shape:Solid
    Molecular weight:448.94
  • Telaglenastat hydrochloride

    CAS:
    <p>Telaglenastat (CB-839) HCl: First-in-class, oral GLS1 inhibitor, targets KGA/GAC, IC50 23-28 nM, triggers autophagy, anticancer.</p>
    Formula:C26H25ClF3N7O3S
    Color and Shape:Solid
    Molecular weight:608.04
  • Isodeoxyelephantopin

    CAS:
    <p>Isodeoxyelephantopin can inhibit the growth of various tumor cells.</p>
    Formula:C19H20O6
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:344.36
  • Veliparib

    CAS:
    <p>Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.</p>
    Formula:C13H16N4O
    Purity:98.66% - 99%
    Color and Shape:Solid
    Molecular weight:244.29
  • SBE13

    CAS:
    <p>SBE13 is a selective and potent inhibitor of Plk1 (IC50: 200 pM). SBE13 has a weak effect on Plk2 or Plk3 with IC50 values of &gt;66 μM and 875 nM respectively.</p>
    Formula:C24H27ClN2O4
    Color and Shape:Solid
    Molecular weight:442.94
  • Biochanin A

    CAS:
    <p>Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.</p>
    Formula:C16H12O5
    Purity:97.1% - 98.97%
    Color and Shape:Solid
    Molecular weight:284.26
  • Regorafenib

    CAS:
    <p>Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally</p>
    Formula:C21H15ClF4N4O3
    Purity:98% - 99.95%
    Color and Shape:Solid
    Molecular weight:482.82
  • Nur77 modulator 1

    CAS:
    <p>Nur77 modulator 1: binds at 3.58 μM, boosts expression, alters location, triggers ER stress/autophagy, induces apoptosis, and fights hepatoma.</p>
    Formula:C28H25N5O2S
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:495.6
  • KM11060

    CAS:
    <p>KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma</p>
    Formula:C19H17Cl2N3O2S
    Purity:98.86%
    Color and Shape:Solid
    Molecular weight:422.33
  • Pirarubicin HCl

    CAS:
    <p>Pirarubicin HCl, a less cardiotoxic doxorubicin analogue, hinders DNA replication and repairs by intercalating into DNA and inhibiting topoisomerase II.</p>
    Formula:C32H38ClNO12
    Color and Shape:Solid
    Molecular weight:664.1
  • Fasudil hydrochloride

    CAS:
    <p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>
    Formula:C14H18ClN3O2S
    Purity:99.54% - ≥95%
    Color and Shape:White Solid
    Molecular weight:327.83
  • Torin 2

    CAS:
    <p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>
    Formula:C24H15F3N4O
    Purity:98.31% - 99.32%
    Color and Shape:Solid
    Molecular weight:432.4
  • Crenolanib

    CAS:
    <p>Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).</p>
    Formula:C26H29N5O2
    Purity:98.40% - 99.73%
    Color and Shape:Solid
    Molecular weight:443.54
  • NUCC-390 dihydrochloride

    CAS:
    <p>NUCC-390, a selective CXCR4 agonist, promotes nerve repair by inducing CXCR4 internalization, opposite to AMD3100.</p>
    Formula:C23H35Cl2N5O
    Color and Shape:Solid
    Molecular weight:468.46
  • Nordihydroguaiaretic acid

    CAS:
    <p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>
    Formula:C18H22O4
    Purity:97.82% - 99.91%
    Color and Shape:Solid
    Molecular weight:302.36
  • Genistein

    CAS:
    <p>Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.</p>
    Formula:C15H10O5
    Purity:98.22% - 99.64%
    Color and Shape:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether Solid
    Molecular weight:270.24
  • (1E,6E)-Bis(demethoxy)curcumin

    CAS:
    <p>(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.</p>
    Formula:C19H16O4
    Purity:97.45%
    Color and Shape:Solid
    Molecular weight:308.33
  • Venetoclax

    CAS:
    <p>Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki &lt; 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).</p>
    Formula:C45H50ClN7O7S
    Purity:98.00% - 99.97%
    Color and Shape:Solid
    Molecular weight:868.44
  • PD146176

    CAS:
    <p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>
    Formula:C15H11NS
    Purity:98.00%
    Color and Shape:Solid
    Molecular weight:237.32
  • EIPA

    CAS:
    <p>EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.</p>
    Formula:C11H18ClN7O
    Purity:96.62% - 99.981%
    Color and Shape:Off-White To Yellow Solid
    Molecular weight:299.76
  • AG490

    CAS:
    <p>AG490 inhibits EGFR (0.1 μM IC50), 135x &gt; selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>
    Formula:C17H14N2O3
    Purity:98.6% - 99.39%
    Color and Shape:Yellow Solid
    Molecular weight:294.3
  • Tomatidine

    CAS:
    <p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>
    Formula:C27H45NO2
    Purity:99.94% - 99.98%
    Color and Shape:Solid
    Molecular weight:415.65
  • GNE-7915

    CAS:
    <p>GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.</p>
    Formula:C19H21F4N5O3
    Purity:98% - ≥95%
    Color and Shape:Solid
    Molecular weight:443.4
  • Troglitazone

    CAS:
    <p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>
    Formula:C24H27NO5S
    Purity:98% - 99.8%
    Color and Shape:Yellow Solid
    Molecular weight:441.54
  • Lumacaftor

    CAS:
    <p>Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.</p>
    Formula:C24H18F2N2O5
    Purity:99.48% - 99.68%
    Color and Shape:Solid
    Molecular weight:452.41
  • Dehydropachymic acid

    CAS:
    <p>Dehydropachymic acid shows antiinflammatory activity.</p>
    Formula:C33H50O5
    Purity:99.61% - 99.78%
    Color and Shape:Solid
    Molecular weight:526.75
  • Glyphosate

    CAS:
    <p>Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.</p>
    Formula:C3H8NO5P
    Purity:99.12% - 99.91%
    Color and Shape:White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)
    Molecular weight:169.07
  • Notoginsenoside Fc

    CAS:
    <p>1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.</p>
    Formula:C58H98O26
    Purity:99.22% - 99.94%
    Color and Shape:Solid
    Molecular weight:1211.38
  • GNE-7915 tosylate

    CAS:
    <p>GNE-7915 tosylate is a potent, selective, and brain-penetrant LRRK2 inhibitor, boasting an IC50 value of 9 nM.</p>
    Formula:C26H29F4N5O6S
    Color and Shape:Solid
    Molecular weight:615.6
  • Cilofexor

    CAS:
    <p>Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.</p>
    Formula:C28H22Cl3N3O5
    Purity:99.86% - ≥95%
    Color and Shape:Solid
    Molecular weight:586.85
  • Talarozole

    CAS:
    <p>Talarozole is an oral RAMBA for treating acne and psoriasis, inhibiting CYP26A1/26B1 with IC50s of 5.4/0.46 nM.</p>
    Formula:C21H23N5S
    Purity:97.51%
    Color and Shape:Solid
    Molecular weight:377.51
  • Rosuvastatin

    CAS:
    <p>Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.</p>
    Formula:C22H28FN3O6S
    Purity:95.24% - 99.8%
    Color and Shape:Solid
    Molecular weight:481.54
  • STF-31

    CAS:
    <p>STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.</p>
    Formula:C23H25N3O3S
    Purity:99.55% - >99.99%
    Color and Shape:Solid
    Molecular weight:423.53
  • Dehydrocorydaline

    CAS:
    <p>1.</p>
    Formula:C22H24NO4
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:366.43
  • Hydroxychloroquine

    CAS:
    <p>HCQ, an anti-malarial, may induce cancer cell death and is being explored for COVID-19.</p>
    Formula:C18H26ClN3O
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:335.87
  • Lapatinib tosylate

    CAS:
    <p>Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) &amp; 9.8 nM (ErbB-2).</p>
    Formula:C36H34ClFN4O7S2
    Color and Shape:Solid
    Molecular weight:753.26
  • FIPI HCl

    CAS:
    <p>FIPI: Selective phospholipase D inhibitor, blocks mercury-induced lipid signals, protects aortic cells.</p>
    Formula:C23H25ClFN5O2
    Color and Shape:Solid
    Molecular weight:457.93
  • Fasudil dihydrochloride

    CAS:
    <p>Fasudil dihydrochloride (HA-1077/AT877) is a RhoA/ROCK inhibitor with kinase-blocking properties and acts as a vasodilator.</p>
    Formula:C14H19Cl2N3O2S
    Color and Shape:Solid
    Molecular weight:364.29
  • PI-1840

    CAS:
    <p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>
    Formula:C22H26N4O3
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:394.47
  • Fasudil hydrochloride hydrate

    CAS:
    <p>Fasudil HCl hydrate is a ROCK inhibitor that hinders mature CCM development and lowers portal pressure in cirrhotic rats.</p>
    Formula:C28H38Cl2N6O5S2
    Color and Shape:Solid
    Molecular weight:673.67
  • Liensinine

    CAS:
    <p>1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.</p>
    Formula:C37H42N2O6
    Purity:98.92% - 99.93%
    Color and Shape:White-Like Powder
    Molecular weight:610.74
  • Retro-2

    CAS:
    <p>Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.</p>
    Formula:C19H16N2OS
    Purity:98.15%
    Color and Shape:Solid
    Molecular weight:320.41
  • Atorvastatin hemicalcium salt

    CAS:
    <p>Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.</p>
    Formula:C33H34FN2O5Ca
    Purity:99.27% - >99.99%
    Color and Shape:White Crystalline Powder
    Molecular weight:577.67
  • Purvalanol A

    CAS:
    <p>Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.</p>
    Formula:C19H25ClN6O
    Purity:98.13% - 99.68%
    Color and Shape:Powder
    Molecular weight:388.89
  • Norepinephrine

    CAS:
    <p>Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway.</p>
    Formula:C8H11NO3
    Purity:99.43% - 99.84%
    Color and Shape:Colorless Microcrystals Solid
    Molecular weight:169.18
  • PHA-665752

    CAS:
    <p>PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), &gt;50-fold selectivity for c-Met than STKs or RTKs.</p>
    Formula:C32H34Cl2N4O4S
    Purity:97.05% - 98.82%
    Color and Shape:Solid
    Molecular weight:641.61
  • CZC-54252

    CAS:
    <p>CZC-54252 is a potent inhibitor of LRRK2.</p>
    Formula:C22H25ClN6O4S
    Purity:99.39%
    Color and Shape:Solid
    Molecular weight:504.99
  • Tacrolimus monohydrate

    CAS:
    <p>Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FKBP to form a complex.</p>
    Formula:C44H71NO13
    Purity:97.07% - 98.05%
    Color and Shape:Solid
    Molecular weight:822.05
  • Nilotinib monohydrochloride monohydrate

    CAS:
    <p>Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosine</p>
    Formula:C28H22F3N7O·HCl·H2O
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:583.99
  • Dorsomorphin

    CAS:
    <p>Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.</p>
    Formula:C24H25N5O
    Purity:98% - 99.06%
    Color and Shape:Solid
    Molecular weight:399.49
  • Glucosamine sulfate

    CAS:
    <p>Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.</p>
    Formula:C6H13NO5·H2SO4
    Purity:99.64%
    Color and Shape:White Crystal
    Molecular weight:277.25
  • Maprotiline

    CAS:
    <p>Maprotiline blocks norepinephrine uptake, has antidepressant properties, and fights cancer by inducing apoptosis and inhibiting ERK and CRABP1.</p>
    Formula:C20H23N
    Color and Shape:Solid
    Molecular weight:277.4
  • Lucanthone hydrochloride

    CAS:
    <p>Lucanthone hydrochloride is a novel acridine derivative which supresses autophagic degradation and triggers apoptosis in colon cancer cells.</p>
    Formula:C20H25ClN2OS
    Color and Shape:Solid
    Molecular weight:376.94
  • Cucurbitacin E

    CAS:
    <p>Cucurbitacin E, from Cucumic melo, inhibits cyclin B1/CDC2, and has neuroprotective, anti-proliferative, anti-cancer, and pain relief properties.</p>
    Formula:C32H44O8
    Purity:98.88% - 99.87%
    Color and Shape:Solid
    Molecular weight:556.69
  • Autogramin-2

    CAS:
    <p>Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either</p>
    Formula:C21H27N3O4S
    Purity:96.25%
    Color and Shape:Solid
    Molecular weight:417.52
  • Vistusertib

    CAS:
    <p>Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.</p>
    Formula:C25H30N6O3
    Purity:97.08% - 99.06%
    Color and Shape:Solid
    Molecular weight:462.54
  • Trifluoperazine

    CAS:
    <p>Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.</p>
    Formula:C21H24F3N3S
    Purity:98.3% - 99.46%
    Color and Shape:White To Yellowish Crystalline Powder
    Molecular weight:407.5
  • Vismodegib

    CAS:
    <p>Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).</p>
    Formula:C19H14Cl2N2O3S
    Purity:98% - 99.82%
    Color and Shape:Solid
    Molecular weight:421.3
  • PFK-158

    CAS:
    <p>PFK-158 is an effective and specific inhibitor PFKFB3.</p>
    Formula:C18H11F3N2O
    Purity:95.49% - 99.16%
    Color and Shape:Solid
    Molecular weight:328.29
  • Trametinib

    CAS:
    <p>Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits &gt;180 kinases.</p>
    Formula:C26H23FIN5O4
    Purity:98% - 99.96%
    Color and Shape:Solid
    Molecular weight:615.39
  • Paris saponin VII

    CAS:
    <p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>
    Formula:C51H82O21
    Purity:99.51% - 99.63%
    Color and Shape:Solid
    Molecular weight:1031.18
  • Levosimendan

    CAS:
    <p>Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.</p>
    Formula:C14H12N6O
    Purity:99.37% - 99.91%
    Color and Shape:Yellow Crystalline Powder
    Molecular weight:280.28
  • Wogonin

    CAS:
    <p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>
    Formula:C16H12O5
    Purity:98% - 99.8%
    Color and Shape:Yellow Crystal
    Molecular weight:284.26
  • SU9516

    CAS:
    <p>SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.</p>
    Formula:C13H11N3O2
    Purity:99.34% - 99.87%
    Color and Shape:Solid
    Molecular weight:241.25
  • DBEQ

    CAS:
    <p>DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.</p>
    Formula:C22H20N4
    Purity:98.93% - ≥95%
    Color and Shape:Solid
    Molecular weight:340.42
  • Nesolicaftor

    CAS:
    <p>Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.</p>
    Formula:C18H18N4O4
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:354.36
  • Degrasyn

    CAS:
    <p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>
    Formula:C19H18BrN3O
    Purity:98.32% - 99.98%
    Color and Shape:Solid
    Molecular weight:384.27
  • 10058-F4

    CAS:
    <p>10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest &amp; apoptosis.</p>
    Formula:C12H11NOS2
    Purity:98% - 99.87%
    Color and Shape:Solid
    Molecular weight:249.35
  • UBCS039

    CAS:
    <p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>
    Formula:C16H13N3
    Purity:98.31%
    Color and Shape:Solid
    Molecular weight:247.29
  • Ataluren

    CAS:
    <p>Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.</p>
    Formula:C15H9FN2O3
    Purity:99.16% - 99.84%
    Color and Shape:Solid
    Molecular weight:284.24
  • SRT 1720

    CAS:
    <p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is &gt;230-fold less potent for SIRT2 and SIRT3.</p>
    Formula:C25H23N7OS
    Purity:98.84%
    Color and Shape:Solid
    Molecular weight:469.56
  • BAY 11-7082

    CAS:
    <p>BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).</p>
    Formula:C10H9NO2S
    Purity:98% - 99.92%
    Color and Shape:Solid
    Molecular weight:207.25
  • L-779450

    CAS:
    <p>L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays &gt;7, &gt;30 and &gt;70-fold selectivity over p38α, GSK3β and Lck respectively.</p>
    Formula:C20H14ClN3O
    Purity:≥95%
    Color and Shape:Solid
    Molecular weight:347.8
  • Gemcitabine hydrochloride

    CAS:
    <p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>
    Formula:C9H11F2N3O4·HCl
    Purity:99.28% - 99.98%
    Color and Shape:White Crystalline Granular Odorless
    Molecular weight:299.66
  • Vps34-PIK-III

    CAS:
    <p>Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates.</p>
    Formula:C17H17N7
    Purity:98.39% - 98.43%
    Color and Shape:Solid
    Molecular weight:319.36
  • Rottlerin

    CAS:
    <p>Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.</p>
    Formula:C30H28O8
    Purity:97.41% - 99.44%
    Color and Shape:Orange To Brown Powder
    Molecular weight:516.54
  • Rosiglitazone hydrochloride

    CAS:
    <p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>
    Formula:C18H19N3O3S·HCl
    Purity:99.63% - 99.79%
    Color and Shape:Solid
    Molecular weight:393.89
  • Olaparib

    CAS:
    <p>View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.</p>
    Formula:C24H23FN4O3
    Purity:98% - >99.99%
    Color and Shape:Solid
    Molecular weight:434.46
  • BL-918

    CAS:
    <p>BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.</p>
    Formula:C23H15F8N3OS
    Purity:99.4% - 99.89%
    Color and Shape:Solid
    Molecular weight:533.44
  • TPEN

    CAS:
    <p>TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.</p>
    Formula:C26H28N6
    Purity:98% - 99.72%
    Color and Shape:White Crystalline Powder
    Molecular weight:424.54
  • RSVA405

    CAS:
    <p>RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor</p>
    Formula:C17H20N4O2
    Purity:99.30%
    Color and Shape:Solid
    Molecular weight:312.37
  • Sevelamer hydrochloride

    CAS:
    <p>Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption</p>
    Formula:(C3H7N·C3H5ClO·HCl)x
    Purity:98%
    Color and Shape:Solid
    Molecular weight:186.08
  • Cucurbitacin B

    CAS:
    <p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>
    Formula:C32H46O8
    Purity:97.1% - 99.33%
    Color and Shape:Solid
    Molecular weight:558.7
  • Zebularine

    CAS:
    <p>Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.</p>
    Formula:C9H12N2O5
    Purity:99.04% - >99.99%
    Color and Shape:Solid
    Molecular weight:228.2
  • Soyasapogenol B

    CAS:
    <p>Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.</p>
    Formula:C30H50O3
    Purity:99.51% - 99.81%
    Color and Shape:Solid
    Molecular weight:458.72
  • Cryptotanshinone

    CAS:
    <p>Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no impact on STAT1/5.</p>
    Formula:C19H20O3
    Purity:97.94% - ≥95%
    Color and Shape:Orange Needle Crystal
    Molecular weight:296.36
  • Idarubicin hydrochloride

    CAS:
    <p>Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).</p>
    Formula:C26H27NO9·HCl
    Purity:98.91% - 99.96%
    Color and Shape:Solid
    Molecular weight:533.95
  • GSK2606414

    CAS:
    <p>GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase(PERK)inhibitor.Cost-effective and quality-assured.</p>
    Formula:C24H20F3N5O
    Purity:98% - >99.99%
    Color and Shape:Solid
    Molecular weight:451.44
  • Panobinostat

    CAS:
    <p>Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.</p>
    Formula:C21H23N3O2
    Purity:97.2% - 99.81%
    Color and Shape:Yellow Solid
    Molecular weight:349.43
  • Crizotinib

    CAS:
    <p>Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.</p>
    Formula:C21H22Cl2FN5O
    Purity:99% - 99.87%
    Color and Shape:Solid
    Molecular weight:450.34
  • SB 216763

    CAS:
    <p>SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).</p>
    Formula:C19H12Cl2N2O2
    Purity:98.9% - 99.13%
    Color and Shape:Solid
    Molecular weight:371.22
  • (+)-JQ-1

    CAS:
    <p>(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.</p>
    Formula:C23H25ClN4O2S
    Purity:97.57% - ≥95%
    Color and Shape:Solid
    Molecular weight:456.99
  • Juglanin

    CAS:
    <p>Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.</p>
    Formula:C20H18O10
    Purity:98.8% - 99.33%
    Color and Shape:Solid
    Molecular weight:418.35
  • LYS01

    CAS:
    <p>LYS01 free base is a new lysosomal autophagy inhibitor.</p>
    Formula:C23H23Cl2N5
    Purity:98.28%
    Color and Shape:Solid
    Molecular weight:440.37
  • Meglutol

    CAS:
    <p>Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.</p>
    Formula:C6H10O5
    Purity:99.73% - 99.94%
    Color and Shape:Solid
    Molecular weight:162.14
  • MRT68921 dihydrochloride

    CAS:
    <p>MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).</p>
    Formula:C25H36Cl2N6O
    Purity:98.91% - 99.92%
    Color and Shape:Solid
    Molecular weight:507.499
  • Berberine hydrogen sulphate

    CAS:
    <p>Berberine hydrogen sulphate, a plant alkaloid, has broad antimicrobial effects on bacteria, fungi, and protozoa.</p>
    Formula:C20H19NO8S
    Purity:99% - 99.79%
    Color and Shape:Yellow Crystals Off-White To Yellow Powder
    Molecular weight:433.43
  • 4,4'-Dimethoxychalcone

    CAS:
    <p>4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.</p>
    Formula:C17H16O3
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:268.31
  • Hoechst 33342 trihydrochloride

    CAS:
    <p>Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.</p>
    Formula:C27H31Cl3N6O
    Purity:98.73% - ≥98%
    Color and Shape:Solid
    Molecular weight:561.93
  • Ixazomib citrate

    CAS:
    <p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>
    Formula:C20H23BCl2N2O9
    Purity:98.37% - >99.99%
    Color and Shape:Solid
    Molecular weight:517.12
  • MG-132

    CAS:
    <p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>
    Formula:C26H41N3O5
    Purity:95% - 99.99%
    Color and Shape:White To Off-White Powder
    Molecular weight:475.62
  • Vps34-IN-1

    CAS:
    <p>Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.</p>
    Formula:C21H24ClN7O
    Purity:97.04%
    Color and Shape:Solid
    Molecular weight:425.91
  • SAR405

    CAS:
    <p>SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.</p>
    Formula:C19H21ClF3N5O2
    Purity:99.42% - 99.79%
    Color and Shape:Solid
    Molecular weight:443.85
  • Galangin

    CAS:
    <p>Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.</p>
    Formula:C15H10O5
    Purity:98.24% - 99.93%
    Color and Shape:Yellowish Needle-Like Crystal
    Molecular weight:270.24
  • CZC-25146

    CAS:
    <p>CZC-25146, a stable LRRK2 inhibitor, IC50: 4.76 nM (wild-type), 6.87 nM (G2019S).</p>
    Formula:C22H25FN6O4S
    Purity:97.68%
    Color and Shape:Solid
    Molecular weight:488.54
  • AZ304

    CAS:
    <p>AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).</p>
    Formula:C27H25N5O2
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:451.52
  • KB-R7943 mesylate

    CAS:
    <p>KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.</p>
    Formula:C17H21N3O6S2
    Purity:99.88% - ≥95%
    Color and Shape:Solid
    Molecular weight:427.5
  • Briciclib

    CAS:
    <p>Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.</p>
    Formula:C19H23O10PS
    Purity:98% - 99.84%
    Color and Shape:Solid
    Molecular weight:474.42
  • JNJ-42165279

    CAS:
    <p>JNJ-42165279 selectively inactivates FAAH without notably affecting other enzymes, ion channels, receptors, or CYPs/hERG at 10 μM.</p>
    Formula:C18H17ClF2N4O3
    Purity:99.67% - 99.88%
    Color and Shape:Solid
    Molecular weight:410.8
  • Hoechst 33342

    CAS:
    <p>Hoechst 33342 (bisBenzimide H 33342) is a benzimidazole fluorescent dye and a cell-permeable fluorescent DNA dye. High-Quality, Low-Cost!</p>
    Formula:C27H28N6O
    Purity:98.12% - 99.75%
    Color and Shape:Yellow-Green Powder
    Molecular weight:452.55
  • Brevilin A

    CAS:
    <p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>
    Formula:C20H26O5
    Purity:99.97% - >99.99%
    Color and Shape:Solid
    Molecular weight:346.42
  • Ponatinib

    CAS:
    <p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>
    Formula:C29H27F3N6O
    Purity:98% - 99.60%
    Color and Shape:Solid
    Molecular weight:532.56
  • Actein

    CAS:
    <p>Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.</p>
    Formula:C37H56O11
    Purity:≥98%
    Color and Shape:Brown Powder
    Molecular weight:676.83
  • Tempol

    CAS:
    <p>Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.</p>
    Formula:C9H18NO2
    Purity:97% - 99.74%
    Color and Shape:4-Hydroxy-Tempo Appears As Orange Flakes Solid Flakes
    Molecular weight:172.25
  • N-​Benzyllinolenamide

    CAS:
    <p>N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).</p>
    Formula:C25H37NO
    Purity:98.7% - 99.92%
    Color and Shape:Solid
    Molecular weight:367.57
  • Peretinoin

    CAS:
    <p>Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.</p>
    Formula:C20H30O2
    Purity:97.23%
    Color and Shape:Solid
    Molecular weight:302.45
  • LC3-mHTT-IN-AN2

    CAS:
    <p>LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.</p>
    Formula:C15H10O4
    Purity:98.82% - ≥98%
    Color and Shape:Solid
    Molecular weight:254.24
  • Rabusertib

    CAS:
    <p>Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.</p>
    Formula:C18H22BrN5O3
    Purity:98.86% - 99.87%
    Color and Shape:Solid
    Molecular weight:436.3
  • SN-38

    CAS:
    <p>SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM).</p>
    Formula:C22H20N2O5
    Purity:98% - 99.97%
    Color and Shape:Light-Yellow Solid
    Molecular weight:392.4
  • Ethyl 3,4-dihydroxybenzoate

    CAS:
    <p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>
    Formula:C9H10O4
    Purity:99.88%
    Color and Shape:White Crystal Or Powder
    Molecular weight:182.17
  • AS1842856

    CAS:
    <p>AS1842856 is a Foxo1 inhibitor that blocks the transcriptional activity of Foxo1. AS1842856 has autophagy inhibitory activity. Cost-effective and quality-assured.</p>
    Formula:C18H22FN3O3
    Purity:99.36% - >99.99%
    Color and Shape:Solid
    Molecular weight:347.38
  • DMH-1

    CAS:
    <p>DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.</p>
    Formula:C24H20N4O
    Purity:98% - 99.92%
    Color and Shape:Solid
    Molecular weight:380.44
  • SP600125

    CAS:
    <p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>
    Formula:C14H8N2O
    Purity:97.63% - 99.82%
    Color and Shape:Solid
    Molecular weight:220.23
  • Pexmetinib

    CAS:
    <p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>
    Formula:C31H33FN6O3
    Purity:99.07% - 99.66%
    Color and Shape:Solid
    Molecular weight:556.63
  • Vps34-IN-4

    CAS:
    <p>VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)</p>
    Formula:C21H25N7O
    Purity:98.6%
    Color and Shape:Solid
    Molecular weight:391.47
  • 3BDO

    CAS:
    <p>3BDO is a new mTOR activator. 3BDO inhibits autophagy.</p>
    Formula:C18H17NO5
    Purity:97.76%
    Color and Shape:Solid
    Molecular weight:327.33
  • XCT790

    CAS:
    <p>XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).</p>
    Formula:C23H13F9N4O3S
    Purity:99% - 99.61%
    Color and Shape:Solid
    Molecular weight:596.42
  • 20-DEOXYINGENOL

    CAS:
    <p>20-DEOXYINGENOL is a natual product.</p>
    Formula:C20H28O4
    Purity:99.98% - ≥95%
    Color and Shape:Solid
    Molecular weight:332.43
  • Pseudolaric Acid B

    CAS:
    <p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>
    Formula:C23H28O8
    Purity:98.91% - 99.84%
    Color and Shape:Solid
    Molecular weight:432.46
  • U0126

    CAS:
    <p>U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.</p>
    Formula:C18H16N6S2
    Purity:99.61%
    Color and Shape:White Solid
    Molecular weight:380.49
  • Torin 1

    CAS:
    <p>Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.</p>
    Formula:C35H28F3N5O2
    Purity:98.3% - 99.33%
    Color and Shape:Solid
    Molecular weight:607.62
  • Clinofibrate

    CAS:
    <p>Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.</p>
    Formula:C28H36O6
    Purity:>99.99%
    Color and Shape:White Crystalline Powder
    Molecular weight:468.58
  • Alginic acid

    CAS:
    <p>Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.</p>
    Formula:C14H22O13
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:398.317
  • Oleanolic Acid

    CAS:
    <p>Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants.</p>
    Formula:C30H48O3
    Purity:97.04% - 98.51%
    Color and Shape:Solid
    Molecular weight:456.7
  • Tetrahydrocurcumin

    CAS:
    <p>Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.</p>
    Formula:C21H24O6
    Purity:97.81% - 98.82%
    Color and Shape:Solid Powder
    Molecular weight:372.41
  • Salbutamol hemisulfate

    CAS:
    <p>Salbutamol hemisulfate (Albuterol Sulfate) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.</p>
    Formula:C13H21NO3H2O4S
    Purity:99.35%
    Color and Shape:White Or Almost White Odourless Powder
    Molecular weight:576.70
  • JZL195

    CAS:
    <p>JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.</p>
    Formula:C24H23N3O5
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:433.46
  • Acumapimod

    CAS:
    <p>Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 &lt;1 μM).</p>
    Formula:C22H19N5O2
    Purity:≥95%
    Color and Shape:Solid
    Molecular weight:385.42
  • Lithocholic acid

    CAS:
    <p>Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!</p>
    Formula:C24H40O3
    Purity:99.69% - 99.93%
    Color and Shape:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)
    Molecular weight:376.57
  • Scutellarein

    CAS:
    <p>Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.</p>
    Formula:C15H10O6
    Purity:98.02% - 99.63%
    Color and Shape:Solid
    Molecular weight:286.24
  • Vancomycin

    CAS:
    <p>Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibiting</p>
    Formula:C66H75Cl2N9O24
    Purity:98.76% - 99.35%
    Color and Shape:Almost White Powder
    Molecular weight:1449.25
  • URB-597

    CAS:
    <p>URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.</p>
    Formula:C20H22N2O3
    Purity:97.20% - 98.24%
    Color and Shape:Solid
    Molecular weight:338.4
  • Tropifexor

    CAS:
    <p>Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.</p>
    Formula:C29H25F4N3O5S
    Purity:99.3% - 99.85%
    Color and Shape:Solid
    Molecular weight:603.58
  • Obeticholic Acid

    CAS:
    <p>Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.</p>
    Formula:C26H44O4
    Purity:99.88% - 99.97%
    Color and Shape:Solid
    Molecular weight:420.63
  • TG101209

    CAS:
    <p>TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.</p>
    Formula:C26H35N7O2S
    Purity:99% - >99.99%
    Color and Shape:Solid
    Molecular weight:509.67
  • Pifithrin-μ

    CAS:
    <p>Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.</p>
    Formula:C8H7NO2S
    Purity:99.33% - 99.79%
    Color and Shape:Solid
    Molecular weight:181.21
  • Valinomycin

    CAS:
    <p>Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin</p>
    Formula:C54H90N6O18
    Purity:95.37% - 97.16%
    Color and Shape:White Solid
    Molecular weight:1111.32
  • Eupatilin

    CAS:
    <p>Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.</p>
    Formula:C18H16O7
    Purity:98.53% - 99%
    Color and Shape:Solid
    Molecular weight:344.32
  • LYN-1604

    CAS:
    <p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>
    Formula:C33H43Cl2N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:584.62
  • SR9009

    CAS:
    <p>SR9009, a REV-ERB agonist, modulates genes and circadian rhythms, reducing fat mass and improving metabolism in obese mice.</p>
    Formula:C20H24ClN3O4S
    Purity:99.94% - >99.99%
    Color and Shape:Solid
    Molecular weight:437.94
  • BC1618

    CAS:
    <p>BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.</p>
    Formula:C24H24F3NO2
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:415.45