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DUB

DUB

DUB inhibitors target deubiquitinases, enzymes that remove ubiquitin molecules from proteins, thereby regulating the stability, localization, and activity of proteins within the cell. Deubiquitinases play essential roles in various cellular processes, including cell cycle regulation, DNA repair, and immune responses. Dysregulation of DUB activity is linked to cancer, neurodegenerative disorders, and viral infections. Inhibitors of DUBs can modulate these processes, offering potential therapeutic approaches for these conditions. At CymitQuimica, we provide DUB inhibitors to support your research in protein homeostasis, cancer, and neurobiology.

Found 84 products of "DUB"

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  • USP7-IN-6

    CAS:
    <p>USP7-IN-6 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 6.8 nM).</p>
    Formula:C41H43N7O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:729.89
  • USP7-797

    CAS:
    <p>USP7-797 is a selective non-covalent active site USP7 inhibitor, inhibiting USP7 and ubiquitin binding, with anti-tumor, oral and high efficiency properties.</p>
    Formula:C27H28ClN3O3S
    Purity:95.90%
    Color and Shape:Solid
    Molecular weight:510.05
  • USP5-IN-1


    <p>USP5-IN-1, a powerful USP5 deubiquitinase inhibitor, selectively binds with 2.8 μM affinity, blocking USP5's di-ubiquitin cleavage.</p>
    Formula:C19H20ClN3O5S
    Purity:99.76%
    Color and Shape:Soild
    Molecular weight:437.9
  • USP15-IN-1

    CAS:
    <p>USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM).</p>
    Formula:C22H23N3O3
    Purity:99.509% - 99.81%
    Color and Shape:Solid
    Molecular weight:377.44