DHFR
Dihydrofolate reductase (DHFR) is an enzyme that plays a crucial role in the folate cycle, which is essential for DNA synthesis, repair, and methylation. DHFR inhibitors are widely used as chemotherapeutic agents in the treatment of cancer and autoimmune diseases due to their ability to inhibit cell proliferation. At CymitQuimica, we provide a variety of DHFR inhibitors to support your research in cancer therapy, immunology, and molecular biology.
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Pyrimethamine
CAS:58-14-0
Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.
Formula:
C12H13ClN4
Purity:
99.74%
Color and Shape:
Crystals
Molecular weight:
248.71
Ref: TM-T0849
| 50mg | 45.00 € | ||
| 100mg | 56.00 € | ||
| 200mg | 85.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sulfameter
CAS:651-06-9
Sulfameter (Sulfametoxydiazine) is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and …
Formula:
C11H12N4O3S
Purity:
99.85%
Color and Shape:
Crystalline Solid
Molecular weight:
280.3
Ref: TM-T0748
| 1g | 37.00 € | ||
| 5g | 70.00 € | ||
| 10g | 96.00 € | ||
| 1mL*10mM (DMSO) | 46.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY 345899
CAS:10538-99-5
LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: …
Formula:
C20H21N7O7
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
471.42
Ref: TM-T15827
| 1mg | 47.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 232.00 € | ||
| 25mg | 420.00 € | ||
| 50mg | 613.00 € | ||
| 100mg | 891.00 € | ||
| 500mg | 1,756.00 € | ||
| 1mL*10mM (DMSO) | 163.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sulfadoxine
CAS:2447-57-6
Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with …
Formula:
C12H14N4O4S
Purity:
98.36%
Color and Shape:
White Or White Crystalline Powder
Molecular weight:
310.33
Ref: TM-T0836
| 500mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Trimethoprim
CAS:738-70-5
Trimethoprim (NSC-106568) inhibits dihydrofolate reductase, CYP2C8, and OCT2 - an antibacterial agent.
Formula:
C14H18N4O3
Purity:
99.81% - 99.88%
Color and Shape:
White To Yellowish Powder
Molecular weight:
290.32
Ref: TM-T1153
| 500mg | 49.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pemetrexed
CAS:137281-23-3
Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate …
Formula:
C20H21N5O6
Purity:
100% - 99.96%
Color and Shape:
Similar To White Powder
Molecular weight:
427.41
Ref: TM-T0189
| 25mg | 44.00 € | ||
| 50mg | 56.00 € | ||
| 100mg | 77.00 € | ||
| 200mg | 94.00 € | ||
| 500mg | 143.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Diaveridine
CAS:5355-16-8
Diaveridine (AI3-23935) (DVD) is a popular antibacterial synergist that is widely used in combination with …
Formula:
C13H16N4O2
Purity:
99.19%
Color and Shape:
White Solid
Molecular weight:
260.29
Ref: TM-T2204
| 1g | 64.00 € | ||
| 500mg | 49.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
P 218
CAS:1142407-60-0
P 218 is a novel DHFR inhibitor with antimalarial activity and antifolate effects and can …
Formula:
C18H25ClN4O4
Purity:
99.50%
Color and Shape:
Soild
Molecular weight:
396.87
Ref: TM-T73328L
| 1mg | 125.00 € | ||
| 5mg | 295.00 € | ||
| 10mg | 437.00 € | ||
| 25mg | 717.00 € | ||
| 50mg | 1,007.00 € | ||
| 100mg | 1,352.00 € | ||
| 500mg | 2,693.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Methotrexate Diglutamate
CAS:41600-13-9
Methotrexate Diglutamate Small molecule compound present in the liver that acts as a partially purified …
Formula:
C25H29N9O8
Purity:
98.84%
Color and Shape:
Solid
Molecular weight:
583.55
Ref: TM-T25886
| 1mg | 1,523.00 € | ||
| 5mg | 3,065.00 € | ||
| 10mg | 4,139.00 € | ||
| 25mg | 6,147.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DS44960156
CAS:2361327-08-2
DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 …
Formula:
C20H15NO5
Purity:
99.13%
Color and Shape:
Liquid
Molecular weight:
349.34
Ref: TM-T37655
| 1mg | 76.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 244.00 € | ||
| 25mg | 423.00 € | ||
| 50mg | 615.00 € | ||
| 100mg | 884.00 € | ||
| 1mL*10mM (DMSO) | 175.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DHFR-IN-3
CAS:137553-43-6
DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.
Formula:
C8H7BrN4
Purity:
99.59% - 99.61%
Color and Shape:
Solid
Molecular weight:
239.07
Ref: TM-T3693
| 100mg | 45.00 € | ||
| 200mg | 60.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
WR99210
CAS:47326-86-3
WR99210 (BRL 6231 free base) is a DHFR inhibitor with antiparasitic activity.
Formula:
C14H18Cl3N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
394.68
Ref: TM-T17257
| 1mg | 64.00 € | ||
| 5mg | 134.00 € | ||
| 10mg | 203.00 € | ||
| 25mg | 413.00 € | ||
| 50mg | 674.00 € | ||
| 100mg | 900.00 € | ||
| 500mg | 1,805.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Fanotaprim
CAS:2120282-75-7
Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.
Formula:
C19H22N8O
Purity:
97.37%
Color and Shape:
Solid
Molecular weight:
378.43
Ref: TM-T36692
| 1mg | 51.00 € | ||
| 2mg | 72.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 323.00 € | ||
| 50mg | 451.00 € | ||
| 100mg | 637.00 € | ||
| 200mg | 858.00 € | ||
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)
Key enzyme in folate metabolism.
Color and Shape:
Liquid
Molecular weight:
25.6 kDa (predicted)
Ref: TM-TMPH-03535
| 1mg | 2,208.00 € | ||
| 20µg | 346.00 € | ||
| 100µg | 651.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
Dihydrofolate reductase Protein, Human, Recombinant (His)
Key enzyme in folate metabolism.
Color and Shape:
Liquid
Molecular weight:
25.5 kDa (predicted)
Ref: TM-TMPH-01224
| 1mg | 1,630.00 € | ||
| 20µg | 193.00 € | ||
| 100µg | 378.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)
Key enzyme in folate metabolism.
Color and Shape:
Liquid
Molecular weight:
22.0 kDa (predicted)
Ref: TM-TMPH-03581
| 1mg | 2,232.00 € | ||
| 20µg | 350.00 € | ||
| 100µg | 658.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
10-Formylfolic acid
CAS:134-05-4
10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used …
Formula:
C20H19N7O7
Purity:
98.42%
Color and Shape:
Solid
Molecular weight:
469.41
Ref: TM-T24962
| 1mg | 366.00 € | ||
| 5mg | 853.00 € | ||
| 10mg | 1,149.00 € | ||
| 25mg | 1,698.00 € | ||
| 50mg | 2,292.00 € | ||
| 100mg | 3,111.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
LY 222306
CAS:154446-98-7
LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.
Formula:
C19H23N5O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
433.42
Ref: TM-T11921
| 25mg | 1,549.00 € | ||
| 50mg | 2,031.00 € | ||
| 100mg | 2,609.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Piritrexim
CAS:72732-56-0
Piritrexim (BW 301U) is an orally available fat-soluble dihydrofolate reductase inhibitor with pulmonary toxicity used …
Formula:
C17H19N5O2
Purity:
99.13% - 99.68%
Color and Shape:
Solid
Molecular weight:
325.37
Ref: TM-T24644
| 1mg | 327.00 € | ||
| 5mg | 905.00 € | ||
| 25mg | 1,486.00 € | ||
| 50mg | 1,850.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
DS18561882
CAS:2227149-22-4
DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.
Formula:
C28H31F3N4O6S
Purity:
98.27% - 99.63%
Color and Shape:
Solid
Molecular weight:
608.63
Ref: TM-T11103
| 1mg | 115.00 € | ||
| 5mg | 270.00 € | ||
| 10mg | 425.00 € | ||
| 25mg | 772.00 € | ||
| 50mg | 1,243.00 € | ||
| 100mg | 1,689.00 € | ||
| 1mL*10mM (DMSO) | 375.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
