Antibacterial
Antibacterial inhibitors are compounds that target bacterial cells, inhibiting their growth or killing them outright. These inhibitors are essential in the development of treatments for bacterial infections and are widely used in research to study bacterial physiology, resistance mechanisms, and the efficacy of new antibacterial agents. At CymitQuimica, we offer a range of antibacterial inhibitors to support your research in microbiology, infectious diseases, and drug development.
Found 2949 products of "Antibacterial"
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Cetefloxacin
CAS:<p>Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.</p>Formula:C20H16F3N3O3Molecular weight:403.35MtTMPK-IN-1
<p>MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.</p>Formula:C22H24N4O3Color and Shape:SolidMolecular weight:392.45Antitubercular agent-23
<p>Antitubercular agent-23 combats Candida albicans (MIC: 1.1 μg/ml) and M. tuberculosis (MIC: 1 μg/ml).</p>Formula:C20H22FN5O8SColor and Shape:SolidMolecular weight:511.48Antibacterial agent 79
<p>Antibacterial agent 79 is an antibacterial agent.</p>Formula:C18H27N3O2S3Color and Shape:SolidMolecular weight:413.62Ibafloxacine
CAS:<p>Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect against</p>Formula:C15H14FNO3Purity:97.67%Color and Shape:SolidMolecular weight:275.27Enzyme-IN-3 disodium
CAS:<p>Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.</p>Formula:C20H13N3Na2O8S2Color and Shape:SolidMolecular weight:533.442epi-D-Captopril
CAS:<p>epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and functions as an inhibitor of metallo-beta-lactamases (MBLs). The IC50 values of epi-D-Captopril for NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. This compound holds potential for research in MBLs-related antibiotic-resistant infections.</p>Formula:C9H15NO3SColor and Shape:SolidMolecular weight:217.285WQ3810
CAS:<p>WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.</p>Formula:C22H22F3N5O3Purity:98%Color and Shape:SolidMolecular weight:461.44RNAP-σ interaction inhibitor-1
CAS:<p>RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.</p>Formula:C19H11Cl3N2O6S2Color and Shape:SolidMolecular weight:533.792'-Amino-2'-deoxyadenosine
CAS:<p>2'-Amino-2'-deoxyadenosine (9-(2-Amino-2-deoxypentofuranosyl)-9H-purin-6-amine) is a nucleoside antibiotic that effectively inhibits various Mycoplasma strains.</p>Formula:C10H14N6O3Molecular weight:266.26Meclocycline
CAS:<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Formula:C22H21ClN2O8Color and Shape:SolidMolecular weight:476.86Antibacterial agent 75
<p>Antibacterial agent 75 re-sensitizes VRSA to vancomycin.</p>Formula:C22H28N6OColor and Shape:SolidMolecular weight:392.5Urease-IN-1
<p>Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).</p>Formula:C17H12BrFN4O2SColor and Shape:SolidMolecular weight:435.27Anti-MRSA agent 6
<p>Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].</p>Formula:C16H11F2N3Color and Shape:SolidMolecular weight:283.28Nitrovin
CAS:<p>Nitrovin is an antimicrobial growth promoter that induces ROS-mediated non-apoptotic and quasi-apoptotic cell death by targeting TrxR1. It exhibits anticancer activity with IC50 values ranging from 1.31 to 6.60 μM for both tumor and normal cells.</p>Formula:C14H12N6O6Color and Shape:SolidMolecular weight:360.28Streptothricin F
CAS:<p>Streptothricin F is a biochemical.</p>Formula:C19H34N8O8Color and Shape:SolidMolecular weight:502.52TBAJ-5307
CAS:<p>TBAJ-5307 is a broad-spectrum anti-non-tuberculous mycobacteria inhibitor that targets the FO-domain of the engine, preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo [1].</p>Formula:C30H35BrN4O6Color and Shape:SolidMolecular weight:627.53BDM91288
CAS:<p>BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].</p>Formula:C17H22ClN5Color and Shape:SolidMolecular weight:331.84Antibiotic U 44590
CAS:<p>5,6-Dihydro-5-azathymidine exhibits activity against both Gram-positive and Gram-negative bacteria, as well as DNA viruses.</p>Formula:C9H15N3O5Color and Shape:SolidMolecular weight:245.23Anti-MRSA agent 23
CAS:<p>Anti-MRSA agent 23 (compound 11) is a potent agent against methicillin-resistant Staphylococcus aureus. This compound exhibits both antibacterial and antibiofilm properties. It facilitates the healing and reconstruction of MRSA-infected skin wounds by reducing bacterial load, alleviating inflammation, and promoting angiogenesis.</p>Formula:C20H17N5O3SColor and Shape:SolidMolecular weight:407.446Kendomycin
CAS:<p>Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.</p>Formula:C29H42O6Color and Shape:SolidMolecular weight:486.64NDM-1 inhibitor-5
CAS:<p>NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].</p>Formula:C24H23NO4Color and Shape:SolidMolecular weight:389.44Levofloxacin mesylate
CAS:<p>Levofloxacin mesylate is an orally active antibiotic effective against both Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase and topoisomerase IV enzymes. Levofloxacin mesylate is employed in research related to chronic periodontitis, airway inflammation, and BK viremia. Additionally, it possesses anti-Orthopoxvirus activity.</p>Formula:C19H24FN3O7SColor and Shape:SolidMolecular weight:457.473Antibacterial agent 204
CAS:<p>Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].</p>Formula:C14H18N2Color and Shape:SolidMolecular weight:214.31DL-2-Aminopimelic Acid
CAS:<p>DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate.</p>Formula:C7H13NO4Color and Shape:SolidMolecular weight:175.18Antitubercular agent-13
<p>Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.</p>Formula:C18H18N4O5Color and Shape:SolidMolecular weight:370.36Antibacterial agent 81
CAS:<p>Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.</p>Formula:C33H28N2O8Color and Shape:SolidMolecular weight:580.58Pneumolysin-IN-1
CAS:<p>Pneumolysin-IN-1 (compound PB-3), characterized as a targeted small molecule inhibitor of Pneumolysin (PLY) with an IC50 value of 3.1 µM, acts as a pore-blocking agent and an anti-virulence factor. This compound is useful for researching infections caused by Streptococcus pneumoniae [1].</p>Formula:C23H16Cl2N2O4Color and Shape:SolidMolecular weight:455.29LasR antagonist 1
CAS:<p>LasR antagonist 1 (Compound 7), with an IC50 of 0.4 μM, is an effective antagonist of LasR that modulates quorum sensing (QS) in the opportunistic pathogen Pseudomonas aeruginosa [1].</p>Formula:C20H15F3N2O3Color and Shape:SolidMolecular weight:388.34L 689065
CAS:<p>L 689065 is a 5-lipoxygenase inhibitor.</p>Formula:C35H33ClN2O3SPurity:98%Color and Shape:SolidMolecular weight:597.17MA220607
CAS:<p>MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].</p>Formula:C34H38INColor and Shape:SolidMolecular weight:587.58Xeruborbactam isoboxil
CAS:<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Formula:C15H16BFO6Color and Shape:SolidMolecular weight:322.093Diploicin
CAS:<p>Diploicin is a dibenzofuran lactone compound with activity against Gram-positive bacteria, found in lichens (lichens).</p>Formula:C16H10Cl4O5Color and Shape:SolidMolecular weight:424.06HKI12134085
CAS:<p>HKI12134085 (compound 3), an orally administered nitrobenzothiazinone (BTZ) derivative, demonstrates antibacterial efficacy against Mycobacterium tuberculosis. This compound exhibits significant in vivo inhibitory potency within a BALB/c mouse model of Mycobacterium tuberculosis infection [1].</p>Formula:C18H18F3N3O5SColor and Shape:SolidMolecular weight:445.41Mt KARI-IN-1
<p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>Formula:C14H11N5O4S2Color and Shape:SolidMolecular weight:377.4Antitubercular agent-15
<p>Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.</p>Formula:C21H29FN2Color and Shape:SolidMolecular weight:328.47N-Cbz-L-Cysteine
CAS:<p>N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].</p>Formula:C11H13NO4SColor and Shape:SolidMolecular weight:255.29QPX7728 bis-acetoxy methyl ester
CAS:<p>QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.</p>Formula:C15H14BFO8Purity:98%Color and Shape:SolidMolecular weight:352.08Ro 24-4383
CAS:<p>Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.</p>Formula:C32H31FN8O10S2Purity:98%Color and Shape:SolidMolecular weight:770.76BRL-42715
CAS:<p>BRL-42715 is an effective inhibitor of bacterial beta-lactamases.</p>Formula:C10H7N4NaO3SPurity:98%Color and Shape:SolidMolecular weight:286.24MBL-IN-5
CAS:<p>MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.</p>Formula:C20H16ClNO3Color and Shape:SolidMolecular weight:353.80MK-3402
CAS:<p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>Formula:C15H19N9O5S2Color and Shape:SolidMolecular weight:469.50Antifungal agent 38
<p>Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.</p>Formula:C8H12N2S2Color and Shape:SolidMolecular weight:200.32H052
CAS:<p>H052 is a selective inhibitor of Staphylococcus aureus α-hemolysin (Hla). It binds to the Hla monomer, disrupting its interaction with the host cell membrane, thereby blocking pore formation and inhibiting calcium influx, cytotoxicity, and inflammatory response. H052 exhibits inhibitory activity against Hla-induced calcium influx (EC50 = 30 nM in U937 cells) and holds potential for research into lung infections caused by S. aureus.</p>Formula:C21H15ClFN3O4SColor and Shape:SolidMolecular weight:459.88LasR-IN-1
<p>LasR-IN-1 (9g) strongly inhibits LasR, potent vs E. coli, with a 28.13 μM MIC against P. aeruginosa.</p>Formula:C23H21N3O2Color and Shape:SolidMolecular weight:371.43OSUAB-0284
CAS:<p>OSUAB-0284 is an inhibitor of bacterial topoisomerase. It exhibits significant activity against staphylococci, particularly methicillin-resistant Staphylococcus aureus (MRSA). The compound exerts its antibacterial effect by inhibiting bacterial topoisomerase and may be used in research on infections caused by drug-resistant bacteria, including MRSA.</p>Formula:C22H23FN6O6Color and Shape:SolidMolecular weight:486.45Antibacterial agent 278
CAS:<p>Antibacterialagent 278 (compound B1) is an antimicrobial agent that exhibits potent inhibitory activity against Gram-positive bacteria.</p>Formula:C24H17ClF2N4O3Color and Shape:SolidMolecular weight:482.87Palmitanilide
CAS:<p>Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.</p>Formula:C22H37NOColor and Shape:SolidMolecular weight:331.535(R)-ZG197
<p>(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.</p>Formula:C28H35F3N4O3Color and Shape:SolidMolecular weight:532.6Cefclidin
CAS:<p>Cefclidin (Cefclidine) is a cephalosporin compound.</p>Formula:C21H26N8O6S2Color and Shape:SolidMolecular weight:550.611
