CymitQuimica logo
PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.

Subcategories of "PI3K/Akt/mTOR Signaling"

Show 2 more subcategories

Found 1038 products of "PI3K/Akt/mTOR Signaling"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • TDZD-8
    Targetmol
    + Info

    TDZD-8

    CAS:
    <p>TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.</p>
    Formula:C10H10N2O2S
    Purity:97.13% - 99.61%
    Color and Shape:White Solid
    Molecular weight:222.26

    Ref: TM-T6187

  • HTH-01-015
    Targetmol
    + Info

    HTH-01-015

    CAS:
    <p>HTH-01-015 is a selective NUAK1 inhibitor (IC50=100 nM).</p>
    Formula:C26H28N8O
    Purity:98.38% - 99.70%
    Color and Shape:Solid
    Molecular weight:468.55

    Ref: TM-T2374

  • AG 1406
    Targetmol
    + Info

    AG 1406

    CAS:
    <p>AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.</p>
    Formula:C16H18N2O
    Purity:98.12%
    Color and Shape:Solid
    Molecular weight:254.33

    Ref: TM-T4554

  • ARN-3236
    Targetmol
    + Info

    ARN-3236

    CAS:
    <p>ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of &lt;1 nM, 21.63 nM and 6.63 nM</p>
    Formula:C19H16N2O2S
    Purity:98.89% - 99.7%
    Color and Shape:Solid
    Molecular weight:336.41

    Ref: TM-T5993

  • ZD-4190
    Targetmol
    + Info

    ZD-4190

    CAS:
    <p>ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.</p>
    Formula:C19H16BrFN6O2
    Purity:99.12%
    Color and Shape:Solid
    Molecular weight:459.27

    Ref: TM-T5475

  • PP 3
    Targetmol
    + Info

    PP 3

    CAS:
    <p>PP 3 is a Negative control for the Src kinase inhibitor PP 2</p>
    Formula:C11H9N5
    Purity:98.61%
    Color and Shape:Whit To Off-White Solid
    Molecular weight:211.22

    Ref: TM-T23176

  • Leniolisib
    Targetmol
    + Info

    Leniolisib

    CAS:
    <p>Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).</p>
    Formula:C21H25F3N6O2
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:450.46

    Ref: TM-T5166

  • Derazantinib dihydrochloride
    Targetmol
    + Info

    Derazantinib dihydrochloride

    CAS:
    <p>Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.</p>
    Formula:C29H31Cl2FN4O
    Color and Shape:Solid
    Molecular weight:541.49

    Ref: TM-T70143

  • 4-Chloro-2'-bromoacetophenone
    Targetmol
    + Info

    4-Chloro-2'-bromoacetophenone

    CAS:
    <p>4-Chloro-2'-bromoacetophenone against glycogen synthase kinase-3 (GSK-3beta).</p>
    Formula:C8H6BrClO
    Purity:98.34% - 99.41%
    Color and Shape:White To Beige Solid
    Molecular weight:233.49

    Ref: TM-T8908

  • WHI-P180
    Targetmol
    + Info

    WHI-P180

    CAS:
    <p>WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.</p>
    Formula:C16H15N3O3
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:297.31

    Ref: TM-T2032

  • Dacomitinib
    Targetmol
    + Info

    Dacomitinib

    CAS:
    <p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>
    Formula:C24H25ClFN5O2
    Purity:99.4% - 99.72%
    Color and Shape:Solid
    Molecular weight:469.94

    Ref: TM-T2483

  • PF-6274484
    Targetmol
    + Info

    PF-6274484

    CAS:
    <p>PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M and WT-EGFR, respectively.</p>
    Formula:C18H14ClFN4O2
    Purity:97.71%
    Color and Shape:Solid
    Molecular weight:372.78

    Ref: TM-T22396

  • AMG319
    Targetmol
    + Info

    AMG319

    CAS:
    <p>AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, &gt;47-fold selectivity over other PI3Ks. Phase 2.</p>
    Formula:C21H16FN7
    Purity:98.9% - 99.24%
    Color and Shape:Crystalline Solid
    Molecular weight:385.4

    Ref: TM-T6757

  • Taselisib
    Targetmol
    + Info

    Taselisib

    CAS:
    <p>Taselisib (GDC-0032) is an oral PI3K alpha inhibitor with potential cancer-treating properties.</p>
    Formula:C24H28N8O2
    Purity:99.62% - 99.79%
    Color and Shape:Solid
    Molecular weight:460.53

    Ref: TM-T1999

  • Torin 2
    Targetmol
    + Info

    Torin 2

    CAS:
    <p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>
    Formula:C24H15F3N4O
    Purity:98.31% - 99.32%
    Color and Shape:Solid
    Molecular weight:432.4

    Ref: TM-T6100

  • PD158780
    Targetmol
    + Info

    PD158780

    CAS:
    <p>PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.</p>
    Formula:C14H12BrN5
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:330.18

    Ref: TM-T5410

  • Bisindolylmaleimide I
    Targetmol
    + Info

    Bisindolylmaleimide I

    CAS:
    <p>Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.</p>
    Formula:C25H24N4O2
    Purity:98.19% - 98.75%
    Color and Shape:Orange Solid
    Molecular weight:412.48

    Ref: TM-T6513

  • JCN037
    Targetmol
    + Info

    JCN037

    CAS:
    <p>JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).</p>
    Formula:C16H11BrFN3O2
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:376.18

    Ref: TM-T8431

  • PKD-IN-1 dihydrochloride (956121-30-5 free base)
    Targetmol
    + Info

    PKD-IN-1 dihydrochloride (956121-30-5 free base)

    CAS:
    <p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>
    Formula:C18H21Cl3N4O
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:415.75

    Ref: TM-T8957L

  • WHI-P154
    Targetmol
    + Info

    WHI-P154

    CAS:
    <p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>
    Formula:C16H14BrN3O3
    Purity:98% - 99.67%
    Color and Shape:Solid
    Molecular weight:376.2

    Ref: TM-T1985