CymitQuimica logo
PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.

Subcategories of "PI3K/Akt/mTOR Signaling"

Show 2 more subcategories

Found 1038 products of "PI3K/Akt/mTOR Signaling"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Methyl 2,5-dihydroxycinnamate
    Targetmol
    + Info

    Methyl 2,5-dihydroxycinnamate

    CAS:
    <p>Methyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.</p>
    Formula:C10H10O4
    Purity:99.60%
    Color and Shape:Crystalline
    Molecular weight:194.18

    Ref: TM-T22974

  • Allitinib tosylate
    Targetmol
    + Info

    Allitinib tosylate

    CAS:
    <p>Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.</p>
    Formula:C31H26ClFN4O5S
    Purity:98.46% - 98.68%
    Color and Shape:Solid
    Molecular weight:621.08

    Ref: TM-T6331

  • Butein
    Targetmol
    + Info

    Butein

    CAS:
    <p>Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.</p>
    Formula:C15H12O5
    Purity:98.76% - >99.99%
    Color and Shape:Solid
    Molecular weight:272.25

    Ref: TM-T6427

  • CL-387785
    Targetmol
    + Info

    CL-387785

    CAS:
    <p>CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.</p>
    Formula:C18H13BrN4O
    Purity:99.56% - 99.62%
    Color and Shape:Solid
    Molecular weight:381.23

    Ref: TM-T2245

  • AMG319
    Targetmol
    + Info

    AMG319

    CAS:
    <p>AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, &gt;47-fold selectivity over other PI3Ks. Phase 2.</p>
    Formula:C21H16FN7
    Purity:98.9% - 99.24%
    Color and Shape:Crystalline Solid
    Molecular weight:385.4

    Ref: TM-T6757

  • PI3K-IN-1
    Targetmol
    + Info

    PI3K-IN-1

    CAS:
    <p>PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.</p>
    Formula:C31H29N5O6S
    Purity:97.03% - 98%
    Color and Shape:Solid
    Molecular weight:599.66

    Ref: TM-T1826

  • Tuxobertinib
    Targetmol
    + Info

    Tuxobertinib

    CAS:
    <p>Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations. BDTX-189 exhibits anticancer activity.</p>
    Formula:C29H29ClN6O4
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:561.03

    Ref: TM-T9072

  • AR-A014418
    Targetmol
    + Info

    AR-A014418

    CAS:
    <p>AR-A014418 (GSK 3β inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor.</p>
    Formula:C12H12N4O4S
    Purity:>99.99% - ≥95%
    Color and Shape:Solid
    Molecular weight:308.31

    Ref: TM-T1881

  • WYE-687 dihydrochloride
    Targetmol
    + Info

    WYE-687 dihydrochloride

    CAS:
    <p>WYE-687 dihydrochloride is an mTOR inhibitor with IC50 of 7 nM, also targeting PI3Kα (81 nM) and PI3Kγ (3.11 μM).</p>
    Formula:C28H34Cl2N8O3
    Color and Shape:Solid
    Molecular weight:601.53

    Ref: TM-T72270

  • PKD-IN-1 dihydrochloride (956121-30-5 free base)
    Targetmol
    + Info

    PKD-IN-1 dihydrochloride (956121-30-5 free base)

    CAS:
    <p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>
    Formula:C18H21Cl3N4O
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:415.75

    Ref: TM-T8957L

  • WHI-P154
    Targetmol
    + Info

    WHI-P154

    CAS:
    <p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>
    Formula:C16H14BrN3O3
    Purity:98% - 99.67%
    Color and Shape:Solid
    Molecular weight:376.2

    Ref: TM-T1985

  • ETP-46321
    Targetmol
    + Info

    ETP-46321

    CAS:
    <p>ETP-46321 is an effective and orally bioavailable PI3Kα/PI3Kδ inhibitor (Ki: 2.3/14.2 nM).</p>
    Formula:C20H27N9O3S
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:473.55

    Ref: TM-TQ0229

  • RGB-286638 free base
    Targetmol
    + Info

    RGB-286638 free base

    CAS:
    <p>RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.</p>
    Formula:C29H35N7O4
    Purity:98% - 99.91%
    Color and Shape:Solid
    Molecular weight:545.63

    Ref: TM-T2378

  • Olmutinib
    Targetmol
    + Info

    Olmutinib

    CAS:
    <p>Olmutinib (BI1482694) is a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor</p>
    Formula:C26H26N6O2S
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:486.59

    Ref: TM-T8460

  • Gallein
    Targetmol
    + Info

    Gallein

    CAS:
    <p>Gallein (Mordant violet 25) is a small molecule inhibitor of Gβγ activity.</p>
    Formula:C20H12O7
    Purity:85.50% - 95.94%
    Color and Shape:Solid
    Molecular weight:364.31

    Ref: TM-T3040

  • GNF4877
    Targetmol
    + Info

    GNF4877

    CAS:
    <p>GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.</p>
    Formula:C25H27FN6O4
    Purity:98.68% - 99.40%
    Color and Shape:Solid
    Molecular weight:494.52

    Ref: TM-T11447

  • Selective PI3Kδ Inhibitor 1
    Targetmol
    + Info

    Selective PI3Kδ Inhibitor 1

    CAS:
    <p>Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM).</p>
    Formula:C23H20FN7O
    Purity:97.96%
    Color and Shape:Solid
    Molecular weight:429.45

    Ref: TM-T5831

  • (E)-AG 99
    Targetmol
    + Info

    (E)-AG 99

    CAS:
    <p>(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).</p>
    Formula:C10H8N2O3
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:204.18

    Ref: TM-T5155

  • WS6
    Targetmol
    + Info

    WS6

    CAS:
    <p>WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.</p>
    Formula:C29H31F3N6O3
    Purity:97.65% - 99.95%
    Color and Shape:Solid
    Molecular weight:568.59

    Ref: TM-T2106

  • Indirubin-3′-oxime
    Targetmol
    + Info

    Indirubin-3′-oxime

    CAS:
    <p>Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.</p>
    Formula:C16H11N3O2
    Purity:98.34%
    Color and Shape:Solid
    Molecular weight:277.28

    Ref: TM-T9138