PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Found 242 products of "PI3K"
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PIK-93
CAS:<p>PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.</p>Formula:C14H16ClN3O4S2Purity:97.72%Color and Shape:SolidMolecular weight:389.88CH5132799
CAS:<p>CH5132799 has been used in trials studying the treatment of Solid Tumors.</p>Formula:C15H19N7O3SPurity:99.41% - 99.87%Color and Shape:SolidMolecular weight:377.42Seletalisib
CAS:<p>Seletalisib (UCB5857) (UCB5857) is a potent and specific PI3Kδ inhibitor (IC50: 12 nM).</p>Formula:C23H14ClF3N6OPurity:99.81%Color and Shape:SolidMolecular weight:482.85α-Linolenic acid
CAS:<p>α-Linolenic Acid (ALA) is an essential fatty acid. α-Linolenic acid improves memory, inhibits thrombosis, and lowers blood lipids. Cost-effective and quality-assured.</p>Formula:C18H30O2Purity:97.05% - 99.81%Color and Shape:Physical Description Clear Colorless Liquid (Ntp 1992)Molecular weight:278.43GSK2636771
CAS:<p>GSK2636771, an effective, specific, orally bioavailable, PI3Kβ inhibitor, has been used in cancer, lymphoma, solid neoplasm, recurrent solid neoplasm, and</p>Formula:C22H22F3N3O3Purity:98.58% - ≥95%Color and Shape:SolidMolecular weight:433.42Vps34-IN-1
CAS:<p>Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.</p>Formula:C21H24ClN7OPurity:97.04%Color and Shape:SolidMolecular weight:425.91SAR405
CAS:<p>SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.</p>Formula:C19H21ClF3N5O2Purity:99.42% - 99.79%Color and Shape:SolidMolecular weight:443.85PIK-90
CAS:<p>PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) .</p>Formula:C18H17N5O3Purity:98.25% - ≥95%Color and Shape:SolidMolecular weight:351.36A66
CAS:<p>A66 is a specific and effective p110α inhibitor(IC50=32 nM).</p>Formula:C17H23N5O2S2Purity:99.51% - ≥95%Color and Shape:SolidMolecular weight:393.53Linperlisib
CAS:<p>Linperlisib (PI3Kδ-IN-2) is a potent and selective inhibitor of PI3Kδ</p>Formula:C28H37FN6O5SPurity:99.01%Color and Shape:SolidMolecular weight:588.69Vps34-IN-4
CAS:<p>VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)</p>Formula:C21H25N7OPurity:98.6%Color and Shape:SolidMolecular weight:391.47CAY10505
CAS:<p>CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).</p>Formula:C14H8FNO3SPurity:99.69% - 99.74%Color and Shape:SolidMolecular weight:289.28GDC-0326
CAS:<p>GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor).</p>Formula:C19H22N6O3Purity:99.35% - >99.99%Color and Shape:SolidMolecular weight:382.42AZD8186
CAS:<p>AZD8186 is an effective and specific PI3Kβ/δ inhibitor (IC50: 4/12 nM).</p>Formula:C24H25F2N3O4Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:457.47Selective PI3Kδ Inhibitor 1
CAS:<p>Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM).</p>Formula:C23H20FN7OPurity:97.96%Color and Shape:SolidMolecular weight:429.45Pilaralisib analogue
CAS:<p>Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.</p>Formula:C21H16N6O2S2Purity:99.3% - 99.72%Color and Shape:SolidMolecular weight:448.52AZD 6482
CAS:<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Formula:C22H24N4O4Purity:99.79% - 99.95%Color and Shape:SolidMolecular weight:408.45PIK-293
CAS:<p>PIK-293 is a PI3K inhibitor, for PI3Kδ( IC50=0.24 μM), and less potent for PI3Kα/β/ γ.</p>Formula:C22H19N7OPurity:99.88%Color and Shape:SolidMolecular weight:397.43ETP-45658
CAS:<p>ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).</p>Formula:C16H17N5O2Purity:99.14%Color and Shape:SolidMolecular weight:311.34Dactolisib
CAS:<p>Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).</p>Formula:C30H23N5OPurity:97.64% - 99.85%Color and Shape:SolidMolecular weight:469.54
