Organometallic Ligands

<p>MF-438 is a novel chemical catalyst, which is synthesized from specialized organic compounds. Functioning as a highly effective facilitator in chemical reactions, it accelerates reaction rates without being consumed in the process. This catalyst operates at a molecular level, optimizing the energy profile of reactions and thereby increasing yield and efficiency.</p>

<p>Aumitin is an innovative compound that is categorized as a bioactive molecule, which is derived from natural sources such as medicinal plants or microorganisms. It exhibits its mode of action through specific interactions with cellular pathways, potentially modulating key processes within the cell. These interactions can lead to alterations in cellular functions such as signaling, metabolism, or growth regulation.</p>

<p>rac-Enprostil is a synthetic prostaglandin analog derived from the natural compound prostaglandin E2, produced primarily via synthetic chemical processes. This compound functions by mimicking the action of endogenous prostaglandins on the gastrointestinal mucosa. It enhances the secretion of mucus and bicarbonate, promoting mucosal protection and stability. Additionally, rac-Enprostil inhibits gastric acid secretion, thus providing a protective effect against gastric lesions and ulcers.</p>

<p>1,2-Dipalmitoyl-d62-sn-glycero-3-phosphocholine-N,N,N-trimethyl-d9 is a deuterated phospholipid, which is an important tool in biophysical research. This molecule is sourced from the synthetic modification of natural phosphatidylcholine, incorporating deuterium atoms to enhance its utility in specialized studies. The deuterium labeling replaces hydrogen atoms, which significantly reduces background noise and enhances signal clarity in spectroscopic techniques like NMR and neutron scattering.</p>

<p>GAT228 is a herbicide that functions as an enzyme inhibitor, originating from synthetic chemical formulations developed for agricultural use. The mode of action involves inhibiting specific enzymes that are crucial for the growth and survival of certain plant species, thereby disrupting their normal physiological processes. This interruption prevents the synthesis of essential amino acids, ultimately leading to the death of the targeted weeds.</p>

<p>NVP DPP 728 is a DPP IV Inhibitor, which is a small molecule compound derived from pharmaceutical research aimed at targeting metabolic pathways. As a potent inhibitor of dipeptidyl peptidase IV (DPP-IV), it functions by preventing the degradation of incretin hormones, primarily glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). This action enhances the body's ability to regulate glucose levels by increasing insulin secretion in a glucose-dependent manner, while simultaneously suppressing glucagon release.</p>

<p>7-Chloro-3,4-dihydro-2-(3-pyridyl)-1(2H)-naphthalenone is a prenylated aromatic amine that is metabolized to 1,4-benzodioxane by cytochrome P450 enzymes. The enzyme activities of 7-chloro-3,4-dihydro-2-(3-pyridyl)-1(2H)-naphthalenone have been shown to be dose dependent in rat liver microsomes and in testicular incubations. This compound is not reactive with the electron spin resonance spectrometer (ESR) at room temperature but becomes highly reactive when it is warmed up. This increased reactivity may be due to an increase in the concentration of free radicals or an increase in the number of accessible sites on the molecule after warming.</p>

<p>Vapreotide acetate is a synthetic somatostatin analog, which is derived through chemical synthesis to mimic the naturally occurring hormone somatostatin. Its mode of action involves binding to somatostatin receptors, leading to the inhibition of the secretion of several hormones and growth factors, such as growth hormone (GH), insulin, glucagon, and gastrin. This inhibitory effect is achieved due to its structural similarity to somatostatin, allowing it to effectively modulate endocrine and exocrine functions.</p>

<p>CEP-33779 is a small-molecule inhibitor designed to target the Janus kinase 2 (JAK2) enzyme, which is a crucial component in the JAK-STAT signaling pathway originating from pro-inflammatory cytokine and growth factor receptors. Derived through sophisticated medicinal chemistry and pharmacological exploration, CEP-33779 functions by selectively inhibiting JAK2 activity. This inhibition is achieved by binding to the ATP-binding pocket of the JAK2 enzyme, thereby blocking the phosphorylation and subsequent activation of STAT proteins, which are essential for the transcription of genes involved in inflammation and tumor proliferation.</p>

<p>ASP3026 is a selective tyrosine kinase inhibitor, which is a synthetic small molecule derived from advanced pharmaceutical research. Its mode of action involves the selective inhibition of the anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase implicated in a variety of cancers. By blocking the activity of ALK, ASP3026 interferes with critical signaling pathways that are essential for cancer cell proliferation and survival.</p>

<p>Dinitrodenafil is a synthetic phosphodiesterase type 5 (PDE5) inhibitor, which is developed through chemical synthesis. Its mode of action involves inhibiting the PDE5 enzyme, leading to increased levels of cyclic guanosine monophosphate (cGMP) in smooth muscle cells. This results in vasodilation and improved blood flow, particularly in the corpus cavernosum of the penis.</p>

<p>Bay 11-7085 is a synthetic chemical inhibitor that is utilized in scientific research. It is derived from a class of bioactive molecules designed to interfere with specific cellular pathways. Bay 11-7085 functions as a covalent inhibitor of the NF-κB signaling pathway, a critical regulator of immune response and cell survival. By targeting the phosphorylation of IκBα, Bay 11-7085 effectively prevents the translocation of NF-κB to the nucleus, thereby modulating gene expression and inhibiting downstream effects.</p>

<p>Please enquire for more information about N-[4-(3-Aminopiperidin-1-yl)-5-bromo-1H-indol-3-yl]cyclopropanecarboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PAT-1251 hydrochloride is a synthetic compound, classified as a selective serotonin receptor antagonist. It is synthesized through complex organic chemistry processes in a controlled laboratory environment, ensuring high purity and specificity. Its mode of action involves the selective inhibition of the 5-HT3 receptor, a subtype of serotonin receptors, which are ion channels involved in neurotransmission in the central and peripheral nervous systems.</p>

<p>Deriglidole is a synthetic compound, which is an organic molecule developed through chemical synthesis. Its source is a lab-engineered process, designed to provide consistency and precision in its molecular structure. This compound functions by inhibiting specific enzymes involved in critical metabolic pathways, thereby altering the biochemical reactions within cellular systems.</p>

<p>Brobactam sodium is a β-lactamase inhibitor, which is a chemically synthesized compound with the primary function of inactivating β-lactamase enzymes produced by certain bacteria. These enzymes can degrade β-lactam antibiotics, such as penicillins and cephalosporins, rendering them ineffective. Brobactam sodium functions by forming a covalent bond with the active site of β-lactamase enzymes, thus inhibiting their activity and allowing the concomitantly administered β-lactam antibiotic to exert its bactericidal effect on the susceptible pathogens.</p>

<p>PF-03549184 is a novel pharmacological compound, classified as a selective GABA_A receptor modulator. It is synthetically derived through advanced chemical processes to achieve high specificity and potency. The mode of action of PF-03549184 involves targeting specific subtypes of the GABA_A receptor, which plays a significant role in inhibitory neurotransmission in the central nervous system. By modulating these receptors, PF-03549184 enhances synaptic transmission and neural network function.</p>

<p>PYZD-4409 is a synthetic compound designed for use in advanced materials science. It is sourced from a meticulously controlled chemical synthesis process that ensures high purity and specificity. The compound operates through a unique molecular interaction mechanism, enabling it to modify the physical properties of polymer matrices. This interaction enhances the durability and thermal stability of the materials in which it is incorporated.</p>

<p>Milfasartan is an angiotensin II receptor blocker (ARB), which is synthetically derived. Its mode of action involves selectively blocking the binding of angiotensin II to the angiotensin I receptor, a crucial aspect in the regulation of blood pressure. This inhibition results in vasodilation, thereby reducing blood pressure and decreasing the workload on the heart.</p>

<p>AB 1010 is a natural antioxidant derived from plant sources, specifically formulated to exhibit potent free radical scavenging properties. This product operates by neutralizing reactive oxygen species (ROS) and other free radicals, thereby preventing oxidative stress and subsequent cellular damage. The primary mechanism involves the donation of electrons to unstable molecules, effectively stabilizing them and halting further oxidative chain reactions.</p>

<p>1-Deoxy-L-threo-sphinganine-d3 is a deuterated sphingolipid analogue, which is a synthetic derivative obtained through selective hydrogen-deuterium exchange. This compound acts as a stable isotope-labeled internal standard, essential for accurate quantification in mass spectrometry-based lipidomics and metabolomics studies. As an analog of naturally occurring sphingolipids, it participates in cellular signaling by modulating pathways involved in cell growth, differentiation, and apoptosis.</p>

<p>Trk-in-4 is a small molecule inhibitor, which is synthetically derived to target Trk kinases. These kinases, part of the receptor tyrosine kinase family, are critically involved in neurotrophin signaling pathways, impacting cell differentiation, growth, and survival. Trk-in-4 functions by selectively binding to the ATP-binding site of Trk receptors, thereby blocking downstream signaling cascades.</p>

<p>SIRT1 Activator II is a biochemical compound known as a small molecule activator. It is derived from synthetic sources, specifically engineered to interact with cellular pathways involved in aging and metabolism. The mode of action of SIRT1 Activator II involves the activation of the SIRT1 enzyme, a member of the sirtuin family of NAD+-dependent deacetylases. This activation results in the modulation of gene expression relevant to cellular stress resistance, metabolic regulation, and longevity.</p>

<p>Sch-42495 racemate is a synthetic compound, categorized as a central nervous system (CNS) agent, derived from laboratory synthesis. This racemate comprises a mixture of enantiomers that display activity affecting neurotransmitter systems, which makes it of particular interest in neuropharmacology. The mode of action involves modulation of specific receptor pathways in the CNS, potentially influencing neurotransmitter release and receptor sensitivity.<br><br>Scientific investigations have explored Sch-42495 racemate primarily for its potential applications in treating neurological disorders. Its effects on brain chemistry suggest possible use in addressing conditions such as depression, anxiety, and other mood disorders. Researchers are also examining its utility in neuroprotection and cognitive enhancement, given its interactions with neural signaling pathways. While still in experimental phases, the compound's dual-enantiomer profile may offer unique advantages in fine-tuning therapeutic effects and minimizing side effects, making it a promising candidate for future CNS drug development.</p>

<p>Erythro-3,4-dimethyl-alpha-[1-(methylamino)ethyl]benzylalcohol hydrochloride is a synthetic compound, which is a derivative obtained through intricate chemical synthesis. It functions primarily as a norepinephrine-dopamine reuptake inhibitor, thereby influencing the synaptic levels of these neurotransmitters by blocking their reabsorption into presynaptic neurons, which increases their availability in the synaptic cleft.</p>

<p>E 5555 hydrobromide is a psychoactive compound, which is a synthetic derivative developed for research purposes. This product is derived from laboratory synthesis, specifically designed to interact with neurological pathways, reflecting a controlled and reproducible production process. The mode of action involves modulation of neurotransmitter systems, specifically targeting receptors commonly associated with psychiatric and neurological disorders. This interaction alters synaptic transmission, providing insights into receptor function and potential pharmacological profiles.</p>

<p>NVX-207 is a nanoparticle-based vaccine platform, which is engineered using recombinant nanoparticle technology with a protein subunit approach. This vaccine is derived from a proprietary recombinant baculovirus that infects insect cells, enabling the production of dense, protein-filled nanoparticles. This unique mode of action allows for the stable presentation of antigens in a manner that mimics their native conformation, effectively enhancing the host's immune response.</p>

<p>Phytosphingosine acetamide is a bioactive lipid derivative, which is synthesized from phytosphingosine, a naturally occurring component present in the stratum corneum of the skin. Its mode of action involves modulation of ceramide synthesis, improvement of the skin’s barrier function, and inhibition of microbial adherence. This compound effectively integrates into the skin’s lipid matrix and influences cellular processes related to skin health.</p>

<p>PK68 is an innovative chemical compound that serves as a selective protein kinase inhibitor, derived through advanced synthetic chemistry techniques. The compound operates by binding to the ATP-binding pocket of target kinases, effectively inhibiting their activity. This mode of action allows PK68 to modulate various kinase-driven signaling pathways that are crucial in cellular processes.</p>

<p>12:0(2S-OH) ceramide is a bioactive lipid molecule, which is a type of ceramide characterized by a specific chemical structure denoted by its 12 carbon atoms and a 2S-hydroxy group. It is derived from sphingolipids, typically sourced from cellular membranes where sphingolipids are major components. Ceramides are integral to the maintenance of the structural integrity of cell membranes and are involved in diverse cellular functions.</p>

<p>Deramciclane is an anxiolytic medication, which is a synthetic compound derived from chemical synthesis. Its mode of action involves modulating the serotonergic neurotransmission system in the brain. Deramciclane primarily functions as a 5-HT2A receptor antagonist. This interaction is believed to contribute to its anxiolytic properties by balancing serotonin levels, thereby reducing symptoms of anxiety.<br><br>The uses and applications of Deramciclane are predominantly within the field of psychiatry for the management of anxiety disorders. It is administered in therapeutic settings where decreasing excessive neural excitability is desired. Unlike benzodiazepines, which also have anxiolytic effects, Deramciclane does not exhibit sedative or muscle relaxant properties, making it potentially advantageous where cognitive impairment needs to be minimized. Ongoing research is also investigating its effects on other mood disorders, contributing to a broader understanding of its clinical efficacy.</p>

<p>M1001 is a biochemical reagent, which is synthesized through advanced organic chemistry techniques, with a specific mode of action that targets nucleic acid structures. It functions as an intercalating agent, inserting itself between base pairs in DNA strands. This interaction alters DNA topology, making M1001 invaluable for research applications that involve DNA replication, transcription, and repair studies.</p>

<p>Iso IRX-A is a novel isomeric compound, which is synthetically derived from advanced organic chemical processes. Its molecular structure has been meticulously engineered to optimize its stability and reactivity, making it an invaluable tool for researchers investigating complex chemical reactions and synthetic pathways. This compound operates through a unique mode of action that involves precise intermolecular interactions, facilitating the formation and cleavage of chemical bonds with high specificity. The isomer's capability to engage in such targeted reactions makes it an ideal candidate for exploring reaction mechanisms and for use as a reference substance in analytical applications.</p>

<p>Aspochracin is a mycotoxin, which is a naturally occurring product derived from certain fungi, specifically from the genus Aspergillus. It acts by inhibiting protein synthesis in susceptible organisms, altering fundamental cellular processes. As a biologically active compound, Aspochracin has been studied for its potential antibiotic and antifungal properties. Its mode of action involves the disruption of cellular mechanisms crucial for growth and replication, making it a compound of interest in the study of microbial growth inhibitors.</p>

<p>6-Methoxy-2-(5-methyl-2-furyl)-N-[(1-methyl-4-piperidyl)methyl]-7-(3-pyrrolidin-1-ylpropoxy)quinolin-4-amine is a synthetic quinoline derivative, which is developed through a series of targeted chemical modifications of the quinoline core structure. This compound is engineered to interact selectively with specific receptors within the central nervous system, due to its high affinity for particular receptor subtypes. Its molecular architecture facilitates the modulation of neurotransmitter pathways, by either agonistic or antagonistic activities, depending on its application.</p>

<p>Ccr7 Ligand 1 is a synthetic chemotactic cytokine, which is a product designed for research purposes sourced from a specialized laboratory synthesis process. This ligand functions by specifically binding to the CCR7 receptor, thus activating intracellular signaling pathways that are crucial for navigation of cells toward lymphoid organs. It engages in signaling pathways that influence cell migration, maturation, and activation through G-protein coupled receptor mechanisms.</p>

<p>GW 311616A is an experimental immunomodulatory compound, which is synthesized through chemical processes designed to interact with specific biological pathways. The compound works by selectively inhibiting particular enzymes involved in the immune response, thereby modulating inflammatory processes. This mode of action allows researchers to explore its potential in regulating overactive immune systems or in conditions where immune suppression might be beneficial.</p>

<p>2’-Oxo tadalafil is a synthetic compound, specifically a derivative of tadalafil. It is a research chemical derived from chemical modifications and is closely related to phosphodiesterase type 5 (PDE5) inhibitors. Its mode of action involves the inhibition of the PDE5 enzyme, leading to increased levels of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the corpus cavernosum. This action facilitates smooth muscle relaxation and increased blood flow, which are key mechanisms in the treatment of erectile dysfunction.</p>

<p>4-Amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]-benzenesulfonamide dihydrochloride is a sulfonamide antibiotic, commonly known as sulfadiazine dihydrochloride. It is a synthetic antimicrobial agent derived from sulfanilamide, a compound originally extracted from azo dyes. Its mode of action involves inhibiting bacterial dihydropteroate synthase, which leads to the obstruction of folic acid synthesis. This disruption is critical as folic acid is essential for bacterial growth and replication.</p>

<p>Lometrexol disodium is an antifolate chemotherapeutic agent, which is a synthetic derivative of the naturally occurring compound folic acid. Its mechanism of action involves the inhibition of the enzyme glycinamide ribonucleotide formyltransferase (GARFT), which plays a critical role in the de novo purine biosynthesis pathway. By targeting GARFT, Lometrexol disodium effectively disrupts nucleotide synthesis, leading to impaired DNA replication and cell division, primarily affecting rapidly proliferating cancer cells.</p>

<p>NSC305787 is a small molecule modulator, which is derived from synthetic sources. It exhibits its mode of action by interfering with specific cell signaling pathways, ultimately influencing cellular processes. The compound is particularly known for its ability to inhibit or modify the activity of certain proteins involved in these pathways, offering insight into cellular behavior and potential intervention points for various biological systems.</p>

<p>Heparin cofactor II is a serine protease inhibitor (serpin), which is a naturally occurring protein primarily synthesized in the liver. It plays a critical role in the regulation of thrombin, an enzyme involved in blood coagulation. The mechanism of action involves Heparin cofactor II binding to heparin or dermatan sulfate, which significantly enhances its ability to inhibit thrombin by forming a stable complex, thereby reducing thrombin’s activity and preventing the conversion of fibrinogen to fibrin.</p>

<p>Bisphenol A-d6 diglycidyl ether is a deuterated form of an epoxy resin prepolymer, which is a vital compound in polymer chemistry and materials science. It is synthesized through the glycidylation of deuterated bisphenol A, introducing stable isotopic labeling with six deuterium atoms. This isotopic form retains the structural integrity of Bisphenol A diglycidyl ether but enhances its utility in specific scientific applications.</p>

<p>Inhibitor of sodium channels; analgesic</p>

<p>NVP-QAV 680 is a kinase inhibitor, which is a synthetic compound designed to obstruct the enzymatic activity of specific kinases involved in various cellular processes. It is derived from precise chemical synthesis, allowing for targeted interaction with the ATP-binding pockets of kinases pertinent to oncogenic signaling pathways. The mode of action involves competitive inhibition, where NVP-QAV 680 competes with ATP, effectively decreasing the phosphorylation of downstream substrates and resulting in the inhibition of aberrant cell proliferation.</p>

<p>Please enquire for more information about ORM-15341 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about HMN-154 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The AIM-100 is an advanced spectrophotometer, which is a sophisticated instrument originating from the field of optical technology, and it operates through the absorption of light wavelengths for the quantification and analysis of molecular compounds. By utilizing a state-of-the-art monochromator and photodetector, it precisely measures the intensity of light absorbed by a sample as a function of wavelength. This method enables the elucidation of molecular structure, concentration, and interactions within complex mixtures. The AIM-100 is particularly valuable in biochemical and pharmaceutical laboratories, where it contributes to the identification and quantitative analysis of proteins, nucleic acids, and small molecules. Its applications are further extended to environmental science, where it assists in the analysis of pollutants and organic materials in water and soil samples. Scientists leverage the AIM-100 to obtain high-resolution spectra that are critical for research and development, ensuring enhanced accuracy and reliability in experimental outcomes.</p>

<p>N-[(E,2S,3R)-1,3-Dihydroxyoctadec-4-en-2-yl]triacontanamide is a complex lipid molecule, which is typically synthesized or isolated from biological sources such as plant or animal lipids. This compound belongs to a class of fatty acid conjugates known for their structural complexity and biological activities.</p>

<p>RTC-30 is an optogenetic tool, which is a photoresponsive device that operates by altering its chemical structure upon exposure to specific wavelengths of light. This molecule can be precisely controlled through exposure to UV or visible light, leading to reversible changes between its active and inactive forms. RTC-30's mechanism involves photoswitching, a property that allows it to toggle cellular processes on or off, effectively acting as a molecular switch.</p>