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Cytoskeletal Signaling

Cytoskeletal Signaling

Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.

Found 1382 products of "Cytoskeletal Signaling"

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  • Myosin V-IN-1

    CAS:
    <p>Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.</p>
    Formula:C29H26N6O3S
    Purity:98.64% - 98.64%
    Color and Shape:Solid
    Molecular weight:538.62
  • Cepeginterferon alfa-2b

    CAS:
    <p>Cepeginterferon alfa-2b: pegylated interferon with 20 kDa PEG for HCV, PV, ET research.</p>
    Color and Shape:Liquid
  • Tubulin inhibitor 50


    <p>Tubulin inhibitor 50 (compound 07) is a microtubule protein inhibitor that enhances mitochondrial reactive oxygen species levels. It exhibits anticancer activity in HeLa cells with an IC50 value of 0.46 μM, while showing low toxicity in normal cell lines.</p>
    Formula:C16H10ClFN2O2
    Color and Shape:Solid
    Molecular weight:316.04148
  • DSPE-PEG5000-cRGD


    <p>DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.</p>
    Color and Shape:Odour Solid
  • Bimosiamose

    CAS:
    <p>Bimosiamose has anti-inflammatory effects[1].</p>
    Formula:C46H54O16
    Purity:98%
    Color and Shape:Solid
    Molecular weight:862.91
  • hAChE-IN-1


    <p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>
    Formula:C22H24N4O
    Color and Shape:Solid
    Molecular weight:360.45
  • SNIPER(ABL)-013


    <p>SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of</p>
    Formula:C42H52F3N7O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:839.9
  • SRI 37892

    CAS:
    <p>SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell viability.</p>
    Formula:C26H19N5O2S
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:465.53
  • 187-1, N-WASP inhibitor

    CAS:
    <p>Inhibits N-WASP by stabilizing its autoinhibited form, blocking PIP2-induced actin assembly (IC50 ~2 μM), not directly affecting actin polymerization.</p>
    Formula:C96H122N18O16
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1784.13
  • Tubulin inhibitor 37


    <p>Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cell</p>
    Formula:C16H10Cl2N6O
    Color and Shape:Solid
    Molecular weight:373.2
  • Tubulin inhibitor 36


    <p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>
    Formula:C16H13ClN6S
    Color and Shape:Solid
    Molecular weight:356.83
  • SIAIS100


    <p>SIAIS100, a potent BCR-ABL PROTAC degrader, demonstrates a DC50 value of 2.7 nM, highlighting its efficacy.</p>
    Formula:C44H50ClF2N9O5S
    Color and Shape:Solid
    Molecular weight:890.44
  • MPC-0767

    CAS:
    <p>MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability.</p>
    Formula:C26H36BrN7O9S2
    Color and Shape:Solid
    Molecular weight:734.64
  • YS-49 monohydrate


    <p>YS-49, a PI3K/Akt activator, curbs RhoA/PTEN; inhibits VSMC growth by inducing HO-1; an isoquinoline alkaloid that stimulates cardiac β-adrenoceptors.</p>
    Formula:C20H22BrNO3
    Color and Shape:Solid
    Molecular weight:404.3
  • JG-258

    CAS:
    <p>JG-258 is an inactive negative control for Hsp70 inhibitors [1] .</p>
    Formula:C20H22ClN3OS3
    Color and Shape:Solid
    Molecular weight:452.06
  • ML 2-23


    <p>ML 2-23 is a potent BCR-ABL degrader operating as a PROTAC, exhibiting selective proteasome-dependent degradation of BCR-ABL within leukemia cells [1].</p>
    Formula:C47H53BrCl2N10O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1052.86
  • Zolbetuximab MMAE


    <p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
    Molecular weight:150 kDa
  • Protein Kinase C (19-36)

    CAS:
    <p>Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.</p>
    Formula:C93H159N35O24
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2151.48
  • Orbofiban acetate

    CAS:
    <p>Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered</p>
    Formula:C19H27N5O6
    Color and Shape:Solid
    Molecular weight:421.45
  • Integrin Binding Peptide

    CAS:
    <p>Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.</p>
    Formula:C42H63N15O16S
    Color and Shape:Solid
    Molecular weight:1066.12