Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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Pre-084
CAS:<p>Pre-084 is a high affinity, selective σ1 agonist.</p>Formula:C19H28ClNO3Purity:99.91%Color and Shape:SolidMolecular weight:353.88Shepherdin 79-87 acetate
<p>Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.</p>Formula:C43H68N12O14SPurity:98.08%Color and Shape:SolidMolecular weight:1009.14AZ13705339 hemihydrate
<p>AZ13705339 hemihydrate: potent PAK1 inhibitor (IC50: 0.33 nM), also binds PAK1/2 (Kd: 0.28/0.32 nM), for cancer research.</p>Formula:C33H36FN7O3SH2OColor and Shape:SolidMolecular weight:638.77Bexotegrast
CAS:<p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>Formula:C27H36N6O3Purity:99.53%Color and Shape:SolidMolecular weight:492.61Alvespimycin
CAS:<p>Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.</p>Formula:C32H48N4O8Purity:99.88%Color and Shape:SolidMolecular weight:616.75FAK activator 1
CAS:<p>ZINC40099027 is a FAK activator that induces gastric mucosal repair in persistent aspirin-associated gastric injury.</p>Formula:C23H26F3N3O3Purity:99.19%Color and Shape:SoildMolecular weight:449.47RO0270608
CAS:<p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>Formula:C24H19Cl3N2O4Purity:98.26%Color and Shape:SolidMolecular weight:505.78Muromonab
CAS:<p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>Purity:95% - 97.51% (SEC-HPLC)Color and Shape:LiquidNeurodazine
CAS:<p>Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.</p>Formula:C27H21ClN2O3Purity:98.01%Color and Shape:SolidMolecular weight:456.92Bosutinib hydrate
CAS:<p>Bosutinib hydrate (SKI-606 hydrate) is a kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of leukemia.</p>Formula:C26H31Cl2N5O4Purity:99.87%Color and Shape:SolidMolecular weight:548.46Etaracizumab
CAS:<p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>Purity:96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.3 (kDa)Vevorisertib trihydrochloride
CAS:<p>Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is ainhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3.</p>Formula:C35H41Cl3N8OPurity:98.28%Color and Shape:SolidMolecular weight:696.12Ruboxistaurin hydrochloride
CAS:<p>Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.</p>Formula:C28H28N4O3·HClPurity:98.44% - 99.22%Color and Shape:SolidMolecular weight:505.01H-Ile-Lys-Val-Ala-Val-OH
CAS:<p>H-Ile-Lys-Val-Ala-Val-OH can induce rapid differentiation of neural progenitor cells into neurons and neurite growth.</p>Formula:C25H48N6O6Purity:99.92%Color and Shape:SolidMolecular weight:528.69Arg-Gly-Asp-Ser
CAS:<p>Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.</p>Formula:C15H27N7O8Purity:98.29%Color and Shape:SolidMolecular weight:433.42NQTrp
CAS:<p>NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.</p>Formula:C21H16N2O4Purity:98.35%Color and Shape:SolidMolecular weight:360.36Mps1-IN-2
CAS:<p>Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.</p>Formula:C26H36N6O3Purity:96.24% - 99.75%Color and Shape:SolidMolecular weight:480.6WZU-13
CAS:<p>WZU-13 is an inhibitor of carboxylesterase (CES). At a concentration of 100 μM, WZU-13 suppresses 77% of CES activity.</p>Formula:C22H16N2OColor and Shape:SolidMolecular weight:324.38Anti-Mouse CD3ε Antibody (145-2C11)
<p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>Purity:99%Color and Shape:Odour LiquidST-401
CAS:<p>ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.</p>Formula:C24H20N2OColor and Shape:SolidMolecular weight:352.43Vepsitamab
CAS:<p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>Color and Shape:LiquidPinatuzumab
CAS:<p>Pinatuzumab is a humanised monoclonal antibody targeting CD22, B-cell malignancies non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukaemia (CLL).</p>Purity:95%Color and Shape:LiquidPasotuxizumab
CAS:<p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.</p>Color and Shape:LiquidTepoditamab
CAS:<p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>Color and Shape:LiquidGresonitamab
CAS:<p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>Color and Shape:LiquidObrindatamab
CAS:<p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>Color and Shape:LiquidEnlimomab
CAS:<p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>Color and Shape:LiquidNivatrotamab
<p>Nivatrotamab: Humanized anti-GD2/CD3 bispecific antibody for neuroblastoma research.</p>Color and Shape:Odour LiquidSemorinemab
CAS:<p>Semorinemab (RG6100) is a humanised monoclonal antibody targeting the N-terminal domain of tau protein with a Kd of 3.8 nM, suitable for Alzheimer's disease.</p>Purity:95% - 95%Color and Shape:Liquid4-Desacetylvinblastine hydrazide
CAS:<p>Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.</p>Formula:C43H56N6O7Color and Shape:SolidMolecular weight:768.94Raludotatug
CAS:<p>Raludotatug is a humanized antibody targeting cadherin-6 (CDH6). As part of the ADC Raludotatug deruxtecan, it shows promise in researching platinum-sensitive ovarian cancer.</p>Purity:95% - 95%Color and Shape:LiquidGosuranemab
CAS:<p>Gosuranemab (BMS-986168), a humanized IgG4 mAb, targets tau residues 15-22, and may aid in Alzheimer’s research.</p>Purity:95% - 95%Color and Shape:LiquidMeclofenamate sodium hydrate
CAS:<p>Meclofenamate sodium: a strong NSAID inhibiting leukocyte function—chemotaxis, degranulation, and radical production.</p>Formula:C14H12Cl2NNaO3Color and Shape:SolidMolecular weight:336.15Posdinemab
CAS:<p>Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].</p>Color and Shape:LiquidPlamotamab
CAS:<p>Plamotamab (XmAb-13676) is a bispecific antibody targeting CD3 and CD20, recruiting T cells to destroy CD20+ tumors and causing mild hematologic reactions.</p>Color and Shape:LiquidAnti-Mouse IL-1a Antibody (ALF-161)
<p>Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.</p>Purity:98%Color and Shape:Odour LiquidUbamatamab
CAS:<p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>Color and Shape:LiquidOsemitamab
CAS:<p>Osemitamab (TST001) is a humanised monoclonal antibody targeting claudin-18.2, gastric/gastric-oesophageal junction adenocarcinoma, PDAC, and lung cancer.</p>Purity:95%Color and Shape:LiquidVoxalatamab
CAS:<p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>Color and Shape:LiquidVonsetamig
CAS:<p>Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.</p>Color and Shape:LiquidFlotetuzumab
CAS:<p>Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.</p>Color and Shape:LiquidPacanalotamab
CAS:<p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>Color and Shape:LiquidVibecotamab
CAS:<p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>Color and Shape:LiquidOS-2966
<p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>Purity:95%Color and Shape:Odour LiquidRovelizumab
CAS:<p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>Color and Shape:LiquidLixudebart
CAS:<p>Lixudebart is a humanised monoclonal antibody targeting CLDN1 (Claudin-1), which can be used to reverse organ fibrosis and reduce initial ALT/AST levels.</p>Purity:95%Color and Shape:LiquidVatelizumab
CAS:<p>Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.</p>Purity:95%Color and Shape:LiquidLinvoseltamab
CAS:<p>Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/</p>Color and Shape:LiquidCevostamab
CAS:<p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>Color and Shape:LiquidOdronextamab
CAS:<p>Odronextamab, a fully human, hinge-stabilized IgG4-based bispecific antibody, targets CD3 receptors on T cells and CD20 receptors on B cells [1].</p>Color and Shape:Liquid
