Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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Tubulin inhibitor 12
CAS:<p>New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.</p>Formula:C24H20N2OColor and Shape:SolidMolecular weight:352.43BCR-ABL1-IN-1
CAS:<p>BCR-ABL1-IN-1: potent, orally active ABL kinase inhibitor with high specificity, promising for CNS research.</p>Formula:C18H12F3N3O2Color and Shape:SolidMolecular weight:359.3KY-04031
CAS:<p>KY-04031 is an inhibitor of p21-activated kinase 4.</p>Formula:C21H20N8OColor and Shape:SolidMolecular weight:400.44AFG210
CAS:<p>AFG210 is a novel first-generation “type II” FLT3 inhibitor.</p>Formula:C19H14F3N3O2Color and Shape:SolidMolecular weight:373.33BCR-ABL-IN-5
CAS:<p>BCR-ABL-IN-5: Bcr-Abl kinase inhibitor, IC50: Bcr-AblWT 0.014 μM, Bcr-AblT315I 0.45 μM; anti-leukemia cell growth.</p>Formula:C25H21Cl2N5O2Color and Shape:SolidMolecular weight:494.37Iso-Fludelone
CAS:<p>Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.</p>Formula:C27H36F3NO6Color and Shape:SolidMolecular weight:527.5710-DEBC hydrochloride
CAS:<p>10-DEBC hydrochloride, a selective Akt inhibitor demonstrating an IC50 value of 1.28 μM, is identified as a novel anti-tuberculosis compound [1] [2].</p>Formula:C20H26Cl2N2OColor and Shape:SolidMolecular weight:381.34DRP1i27
CAS:<p>DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.</p>Formula:C20H26N6OColor and Shape:SolidMolecular weight:366.46KY-04045
CAS:<p>KY-04045 is a PAK4 inhibitor.</p>Formula:C13H14BrN5Color and Shape:SolidMolecular weight:320.19NAMI-A
CAS:<p>NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.</p>Formula:C8H15Cl4N4ORuSPurity:98%Color and Shape:SolidMolecular weight:458.18SSTC3
CAS:<p>SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.</p>Formula:C23H17F3N4O3S2Purity:98.65% - 99.94%Color and Shape:SolidMolecular weight:518.53CHMFL-ABL-053
CAS:<p>CHMFL-ABL-053: potent, selective BCR-ABL/SRC/p38 inhibitor (IC50: 70/90/62 nM). Orally available, potential CML drug.</p>Formula:C28H26F3N7O2Color and Shape:SolidMolecular weight:549.55BuChE-IN-5
CAS:<p>"BuChE-IN-5 is a potent inhibitor with an IC50 of 1.94 μM and shows promise for Alzheimer's research."</p>Formula:C25H35N3Color and Shape:SolidMolecular weight:377.57Microtubule inhibitor 5
CAS:<p>Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.</p>Formula:C22H15FN2O4Color and Shape:SolidMolecular weight:390.36AJH-836
CAS:<p>AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation of</p>Formula:C22H38O5Purity:98%Color and Shape:SolidMolecular weight:382.53Tubulin inhibitor 27
CAS:<p>DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.</p>Formula:C21H19NO4Color and Shape:SolidMolecular weight:349.38Tubulin polymerization-IN-10
CAS:<p>Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.</p>Formula:C18H21NO6SColor and Shape:SolidMolecular weight:379.43HSP90-IN-22
CAS:<p>HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM in</p>Formula:C25H30N4O3Purity:98%Color and Shape:SolidMolecular weight:434.53YM-1
CAS:<p>YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.</p>Formula:C20H20ClN3OS2Color and Shape:SolidMolecular weight:417.98Sibrafiban
CAS:<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Formula:C20H28N4O6Color and Shape:SolidMolecular weight:420.46Neuroinflammatory-IN-3
CAS:<p>Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.</p>Formula:C19H19ClO3Color and Shape:SolidMolecular weight:330.81Tubulin polymerization-IN-36
CAS:<p>Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.</p>Formula:C18H18N2O3Color and Shape:SolidMolecular weight:310.35Tubulin polymerization-IN-16
CAS:<p>Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.</p>Formula:C24H27N5O5Color and Shape:SolidMolecular weight:465.5BCR-ABL-IN-6
CAS:<p>BCR-ABL-IN-6, an imatinib derivative, inhibits Bcr-AblWT (4.6 nM IC50) and T315I (277 nM), for chronic myeloid leukemia study.</p>Formula:C27H22F3N5O2Color and Shape:SolidMolecular weight:505.49Retaspimycin
CAS:<p>Retaspimycin is a potent and water-soluble Hsp90 inhibitor(EC50s of 119 nM for both Hsp90 and Grp9).</p>Formula:C31H45N3O8Purity:98%Color and Shape:SolidMolecular weight:587.7Tubulin polymerization-IN-15
CAS:<p>Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].</p>Formula:C18H17N3O4Color and Shape:SolidMolecular weight:339.35Tubulin inhibitor 18
CAS:<p>"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."</p>Formula:C22H26O5Color and Shape:SolidMolecular weight:370.44Tubulin polymerization-IN-18
CAS:<p>Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.</p>Formula:C25H25NO6Color and Shape:SolidMolecular weight:435.47GNF-1331
CAS:<p>GNF-1331: potent, selective oral porcupine inhibitor; IC50=12 nM; targets aberrant Wnt signaling in cancers.</p>Formula:C20H20N6O2S2Color and Shape:SolidMolecular weight:440.54Synstab A
CAS:<p>Synstab A is a microtubule stabilizer.</p>Formula:C15H13BrCl3N3O3SColor and Shape:SolidMolecular weight:501.61KUNB31
CAS:<p>KUNB31 is a potent and selective inhibitor of Hsp90β.</p>Formula:C19H18N2O3Color and Shape:SolidMolecular weight:322.36Microtubule inhibitor 7
CAS:<p>Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.</p>Formula:C25H19FN2O5Color and Shape:SolidMolecular weight:446.43(S)-Dolaphenine hydrochloride
CAS:<p>(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.</p>Formula:C11H13ClN2SPurity:98%Color and Shape:SolidMolecular weight:240.75Dihydrocytochalasin B
CAS:<p>Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.</p>Formula:C29H39NO5Purity:98%Color and Shape:SolidMolecular weight:481.62MK-0668
CAS:<p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>Formula:C31H30Cl2N6O6SColor and Shape:SolidMolecular weight:685.58Tau tracer 1
CAS:<p>Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.</p>Formula:C34H23N5O2Color and Shape:SolidMolecular weight:533.591Deox B 7,4
CAS:<p>Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.</p>Formula:C18H18O5Color and Shape:SolidMolecular weight:314.33SW02
CAS:<p>SW02 is a potent ATPase activator of Hsp70 (EC50: 150 μM). SW02 is able to accumulate total tau and phosphorylated tau (pTau).</p>Formula:C19H23BrN2O5Color and Shape:SolidMolecular weight:439.3Tubulin polymerization-IN-30
CAS:<p>Compound 6e inhibits tubulin polymerization, disrupts microtubules, halts G2/M phase, and targets HeLa, SGC-7901, A549 with low IC50.</p>Formula:C22H25N5O3Color and Shape:SolidMolecular weight:407.47Tubulin inhibitor 29
CAS:<p>Compound 3c, a tubulin inhibitor, blocks assembly at colchicine site with IC50 of 1.2 μM; anti-proliferative IC50 7.5 μM in MCF-7 cells.</p>Formula:C12H8F2O2S2Color and Shape:SolidMolecular weight:286.32Microtubule inhibitor 6
CAS:<p>Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.</p>Formula:C24H19FN2O5Color and Shape:SolidMolecular weight:434.42Tubulin inhibitor 31
<p>Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.</p>Formula:C22H19NO2Color and Shape:SolidMolecular weight:329.39BCR-ABL-IN-1
CAS:<p>BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.</p>Formula:C23H21F4N5OPurity:98%Color and Shape:SolidMolecular weight:459.44PD-173956
CAS:<p>PD-173956 is an inhibitor of the Src family tyrosine kinases.</p>Formula:C20H13Cl2FN4OColor and Shape:SolidMolecular weight:415.25Tubulin polymerization-IN-7
CAS:<p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>Formula:C28H24N4O6SColor and Shape:SolidMolecular weight:544.58PF-06651481-00
CAS:<p>PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.</p>Formula:C26H29Cl2N5O3Purity:97.01%Color and Shape:SolidMolecular weight:530.45β-glycosidase-IN-1
CAS:<p>β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.</p>Formula:C13H23NO5Purity:98%Color and Shape:SolidMolecular weight:273.33TCS 2314
CAS:<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Formula:C28H34N4O6Purity:98%Color and Shape:SolidMolecular weight:522.59Anticancer agent 60
CAS:<p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>Formula:C27H33N5O4SColor and Shape:SolidMolecular weight:523.65Cevipabulin
CAS:<p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>Formula:C18H18ClF5N6OPurity:99.53%Color and Shape:SolidMolecular weight:464.82
