Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Microtubule inhibitor 1
CAS:<p>Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity(IC50 = 9-16 nM, in cancer cells).</p>Formula:C21H19NO3Purity:98%Color and Shape:SolidMolecular weight:333.38Tubulin inhibitor 28
CAS:<p>Compound 2g, a tubulin inhibitor with an IC50 of 1.2 μM, inhibits MCF-7 cell proliferation.</p>Formula:C12H8Br2S2Color and Shape:SolidMolecular weight:376.13ARUK3001185
CAS:<p>ARUK3001185 (8l): potent, selective Notum inhibitor; oral, brain-penetrant; IC50=6.7 nM; for rodent disease models.</p>Formula:C9H4Cl2F3N3Color and Shape:SolidMolecular weight:282.05CHPG sodium salt
CAS:<p>CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways.</p>Formula:C8H7ClNNaO3Purity:>99.99%Color and Shape:SolidMolecular weight:223.59Valategrast
CAS:<p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>Formula:C30H32Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:604.95Cardionogen 1
CAS:<p>Wnt signaling modulator</p>Formula:C13H14N4OSPurity:98%Color and Shape:SolidMolecular weight:274.34EMD534085
CAS:<p>EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).</p>Formula:C25H31F3N4O2Purity:98%Color and Shape:SolidMolecular weight:476.53Wnt/β-catenin agonist 1
CAS:<p>Wnt/β-catenin agonist 1 is an agonist of Wnt/β-catenin signalling pathway(EC50 of 0.27 μM).</p>Formula:C22H25N3O2Purity:98%Color and Shape:SolidMolecular weight:363.45BCR-ABL-IN-2
CAS:<p>BCR-ABL-IN-2 is a BCR-ABL1 tyrosine kinase inhibitor (IC50s: 57 nM, 773 nM for ABL1 native and ABL1 T315I).</p>Formula:C24H25Cl2N5O3Purity:98%Color and Shape:SolidMolecular weight:502.39Bimoclomol
CAS:<p>Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.</p>Formula:C14H20ClN3O2Color and Shape:SolidMolecular weight:297.78UR-1505
CAS:<p>UR-1505 is an NF-AT inhibitor that prevents T cell activation without reducing cell viability.</p>Formula:C10H7F5O4Purity:98%Color and Shape:SolidMolecular weight:286.15c-ABL-IN-2
CAS:<p>C-ABL-IN-2 is a potent c-Abl protein inhibitor, promising for research in cancer and neurodegenerative diseases like ALS and PD.</p>Formula:C21H20N4OColor and Shape:SolidMolecular weight:344.41AKT-IN-7
CAS:<p>AKT-IN-7 (compound 1-P1) is a potent inhibitor of AKT. AKT-IN-7 has potential for cancer research.</p>Formula:C23H27ClN6O2Color and Shape:SolidMolecular weight:454.95YW1128
CAS:<p>YW1128 inhibits Wnt/β-catenin signaling (IC50=4.1 nM), reduces β-catenin, affects gene expression, and improves glucose tolerance and weight control in mice.</p>Formula:C20H17N5OColor and Shape:SolidMolecular weight:343.38MT-7
CAS:<p>MT-7 is a tubulin polymerization inhibitor.</p>Formula:C22H17N3O2Purity:98%Color and Shape:SolidMolecular weight:355.39Kif15-IN-1
CAS:<p>Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.</p>Formula:C20H22N4O5SPurity:99.39% - 99.39%Color and Shape:SolidMolecular weight:430.48Anticancer agent 49
CAS:<p>Anticancer agent 49, also 69, hinders cell growth and microtubule aggregation, with potential in solid and blood cancer research.</p>Formula:C26H25N3O4Color and Shape:SolidMolecular weight:443.49Tubulin polymerization-IN-19
CAS:<p>Tubulin aggregation-IN-19 (compound 4) is a potent tubulin aggregation inhibitor that has shown potential in breast cancer and drug-resistant colon cancer.</p>Formula:C25H25NO5Color and Shape:SolidMolecular weight:419.47HSP90-IN-12
CAS:<p>VAC, a potent anti-cancer vibsanin A analog, inhibits cell proliferation and affects HSP90 protein levels.</p>Formula:C25H36O4Color and Shape:SolidMolecular weight:400.55DJ101
CAS:<p>DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.</p>Formula:C23H20N4O3Purity:98%Color and Shape:SolidMolecular weight:400.43Hsp90-IN-15
CAS:<p>Hsp90-IN-15: Hsp90 blocker with anticancer properties; halts S phase, triggers apoptosis, cuts Hsp90 in Hela cells.</p>Formula:C23H27F3N4Color and Shape:SolidMolecular weight:416.48YM-01 Tosylate
CAS:<p>YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.</p>Formula:C27H27N3O4S3Color and Shape:SolidMolecular weight:553.72Displurigen
CAS:<p>Displurigen is an inhibitor of ATPase activity of HSP70.</p>Formula:C15H10O4SPurity:98%Color and Shape:SolidMolecular weight:286.3AKT-IN-9
CAS:<p>AKT-IN-9, a potent AKT inhibitor, may aid breast/prostate cancer studies. See WO2021185238A1.</p>Formula:C24H29ClN6OColor and Shape:SolidMolecular weight:452.98ZW4864 free base
CAS:<p>ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.</p>Formula:C33H42N6O3Purity:99.81%Color and Shape:SolidMolecular weight:570.72Box5
CAS:<p>Box5 blocks Wnt5a, reducing Ca2+ release and cell migration; promising for melanoma studies.</p>Formula:C30H50N6O13S2Color and Shape:SolidMolecular weight:766.88Malonganenone A
CAS:<p>Malonganenone A is a selective plasmodial Hsp70s modulator. It also has antimalarial activity.</p>Formula:C26H38N4O2Color and Shape:SolidMolecular weight:438.61Mivobulin
CAS:<p>Mivobulin is an inhibitor of tubulin .</p>Formula:C17H19N5O2Purity:98%Color and Shape:SolidMolecular weight:325.37NC043
CAS:<p>NC043 is an inhibitor of Wnt/β-catenin signaling, it forms a covalent bond with the Cys-516 residue of CARF.</p>Formula:C20H26O4Purity:98%Color and Shape:SolidMolecular weight:330.42KIF18A-IN-3
CAS:<p>KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.</p>Formula:C28H38N4O5S2Purity:98.45%Color and Shape:SolidMolecular weight:574.76Zaurategrast ethyl ester
CAS:<p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>Formula:C28H29BrN4O3Purity:98%Color and Shape:SolidMolecular weight:549.46IMB-10
CAS:<p>IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.</p>Formula:C19H15NOS2Color and Shape:SolidMolecular weight:337.46(R)-Filanesib
CAS:<p>(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).</p>Formula:C20H22F2N4O2SColor and Shape:SolidMolecular weight:420.48CH5138303
CAS:<p>CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.</p>Formula:C19H18ClN5O2SPurity:98%Color and Shape:SolidMolecular weight:415.9Tau protein aggregation-IN-1
CAS:<p>Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders</p>Formula:C17H11BrN2O2Color and Shape:SolidMolecular weight:355.19CK2-IN-9
CAS:<p>CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter</p>Formula:C23H29N9OColor and Shape:SolidMolecular weight:447.54Zaurategrast ethyl ester sulfate
CAS:<p>Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.</p>Formula:C56H60Br2N8O10SPurity:98%Color and Shape:SolidMolecular weight:1197.01Tubulin polymerization-IN-27
CAS:<p>Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.</p>Formula:C22H20N2O2Color and Shape:SolidMolecular weight:344.41CK548
CAS:<p>CK548 is a novel actin-related protein (Arp)2/3 complex inhibitor.</p>Formula:C15H11BrClNO2SPurity:98%Color and Shape:SolidMolecular weight:384.68SC-10
CAS:<p>SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.</p>Formula:C17H22ClNO2SPurity:99.24% - 99.58%Color and Shape:SolidMolecular weight:339.88MG-2119
CAS:<p>MG-2119 is a potent inhibitor of monomeric tau and α-syn aggregation and can be used to study neurological diseases.</p>Formula:C27H29N5O4Color and Shape:SolidMolecular weight:487.55AN-019
CAS:<p>AN-019 (NRC-019) is a Bcr-Abl kinase inhibitor with antitumor activity for the study of chronic myelogenous leukemia (CML) and breast cancer.</p>Formula:C25H17F6N5OPurity:98.99%Color and Shape:SolidMolecular weight:517.43isoCA-4
CAS:<p>isoCA-4 is a Combretastatin A4 derivative. isoCA-4 is a tubulin polymerization inhibitor with anti-proliferative activities [1].</p>Formula:C18H20O5Color and Shape:SolidMolecular weight:316.35Tubulin polymerization-IN-29
CAS:<p>Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.</p>Formula:C25H20FNO6Color and Shape:SolidMolecular weight:449.43BNC105P
CAS:<p>BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.</p>Formula:C20H21O10PColor and Shape:SolidMolecular weight:452.34856BrCaQ
CAS:<p>6BrCaQ inhibits TRAP1, has antiproliferative effects, and is used in 6BrCaQ-TPP synthesis.</p>Formula:C18H15BrN2O3Color and Shape:SolidMolecular weight:387.23Ellipticine quinone
CAS:<p>Ellipticine quinone (NSC-383230) outperforms mdivi-1 in inhibiting Drp1, reduces lung cancer growth, and lessens IR injury by curbing mitochondrial issues.</p>Formula:C15H8N2O2Color and Shape:SolidMolecular weight:248.24Dynamin IN-1
CAS:<p>Dynamin IN-1 is a potent dynamin inhibitor with an IC 50 value of 1.0 µM .</p>Formula:C23H24N2OColor and Shape:SolidMolecular weight:344.45PU3
CAS:<p>PU3 is an inhibitor of Hsp90.</p>Formula:C19H25N5O3Purity:98%Color and Shape:SolidMolecular weight:371.43Conteltinib
CAS:<p>Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It can be used to study lymphoma.</p>Formula:C32H45N9O3SPurity:98.12% - 99.54%Color and Shape:SolidMolecular weight:635.82
