Toxicology

<p>Applications Mieshuan is a pesticide. It is effective against house and wild rodents, including rats and mice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Teng, T., et al.: Zhonghua Yufang Yixue Zazhi, 13, 220 (1979); Deng, Z.: Chinese J. Preventive Medicine, 13, 220 (1979)<br></p>

<p>Applications An agricultural fungicide. Kresoxim-methyl is also useful in cannabis testing kits as a component of pesticide mixes (P698235).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gold, R.E. et al.: Pestic. Sci., 43, 250 (1995); Creemers, P. et al.: Meded. Fac. Landbouwwet. Univ. Gent, 61, 431 (1996); Gold, R.E. et al: Mod. Fungic. Antifungal Compd., 11, 79 (1996);<br></p>

<p>Applications Ethynyl Estradiol-13C2 is isotope labelled version of Ethynyl Estradiol (E685100) which can be used in biological and analytical studies of simultaneous determination of UV-​filters and estrogens in aquatic invertebrates by modified Quick, Easy, Cheap, Effective, Rugged, and Safe extraction and liquid chromatography tandem mass spectrometry.<br>References 1. Koetsawang, S. et al.: Contraception. 1982 March:25(3) p231-2412. Cuttler, L. et al.: J. Endocrinol. Metab. 1985 Jun;60(6):1087-92.<br></p>

<p>Applications Growth hormone-release inhibiting factor; treatment of severe, acute hemorrhage of gastroduodenal ulcers; experimental antidiabetic.<br>References Brazeau, P., et al.: Science, 179, 77 (1973), Siler, T.M., et al.: J. Clin. Endocrinol. Metab., 37, 632 (1973), Pradayrol, L., et al.: Biochem. Biophys. Res. Commun., 85, 701 (1978), Mandarino, L., et al.: Nature, 291, 76 (1981),<br></p>

<p>Applications Diphacinone is an anticoagulant rodenticide widely used to control rodent infestations.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Eason, C., et al.: Ecotoxicology, 11, 35 (2002), Hegdal, P., et al.: Environ. Toxicol. Chem., 7, 245 (1988), Stone, W., et al.: Environ. Contam. Tox., 70, 34 (2003),<br></p>

<p>Applications Sarafloxacin is a quinolone antibiotic drug that was discontinued in 2001. Useful for biological studies and can be detected with colloidal gold test strips.<br>References Jia, F., et al.: Agric. Biotechnol., 8, 172 (2019)<br></p>

<p>Applications Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.<br>References Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011);<br></p>

<p>Applications A potentially related compound in cephalosporin antibacterial compounds. An isomer of Cefuroxime (C248050).<br>References Chavette, R., et al.: J. Med. Chem., 9, 741 (1966), Miyouchi, M., et al.: J. Chem. Pharm. Bull., 38, 1906 (1990), Sugioka, T., et al.: Chem. Pharm. Bull., 38, 1998 (1990),<br></p>

<p>Applications Pentachlorothioanisole is used in the preparation of arenethiols and arenethiolates as seen in agrochemicals or fungicides.<br>References Dulik, D. et al.: Xenobiotica, 22, 325 (1992); Rakitin, O. et al.: Sci. Synth., 31a, 949 (2007);<br></p>

<p>Stability Hygroscopic<br>Applications Labelled Cyromazine (C989300). Insect growth regulator. Insecticide.<br>References Hall, R.D., et al.: J. Econ. Entomol., 73, 564 (1980), Hart, R.J., et al.: Aust. Vet. J., 59, 104 (1982),<br></p>

<p>Applications A labelled antibacterial used in the treatment of dermatitis herpetiformis.<br>References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>

<p>Stability Hygroscopic<br>Applications N-Ethyl-N-(3-sulfobenzyl)sulfanilic Acid Disodium Salt can be obtained from 3-Sulfobenzaldehyde Sodium Salt (S689165) which can be used for the preparation of a series of novel sulfonamide derivatives, as inhibitors of the enzyme histone deacetylase (HDAC) as a novel approach to the treatment of cancer.<br>References Finn, P., et al.: Helvetica Chimica Acta, 88 (7), 1630 (2005);<br></p>

<p>Applications Quaternary ammonium composition to treat herpes, pseudomonas, staph, hepatitis and other infectious diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Berr, S., et al.: J. Phys. Chem., 91, 4760 (1987), Jones, M., et al.: Eur. J. Pharm. Biopharm., 48, 101 (1999), Okano, L., et al.: Langmuir, 16, 3119 (2000),<br></p>

<p>Impurity Cefixime EP Impurity D<br>Applications (E)-Cefixime is an isomeric impurity of the third generation cephalosporin antibiotic, Cefixime (C242800).<br>References Bian, L. et al.: Yao. Fen. Zaz., 30, 872 (2010); Rajadurai, R. et al.: Anal. Chem. Ind. J., 9, 265 (2010);<br></p>