Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Ethylundecanoic acid is a fatty acid with a hydrocarbon group. It has a molecular weight of 114.16 g/mol and an average particle diameter of 10.5 nm. This compound is soluble in water and can be used as an efficient method for the synthesis of alkenoic acids. 2-Ethylundecanoic acid is not combustible and does not react with strong oxidizing agents, acids, or bases. It has formyl and hydroxyl groups that are located at the terminal end of the molecule, which can be converted to carboxylic acid or alcohol groups by heating it in the presence of hydrogen gas.</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Hydroxymethyl)-2-methyl-1H-imidazole (HMI) is a diamine that has been shown to inhibit translation in mouse fibroblast cells. HMI is used for the treatment of inflammatory diseases such as rheumatoid arthritis and Crohn's disease, and it has also been shown to have haemodynamic effects. The clinical relevance of HMI is not well understood, but it has been found to be an effective anti-inflammatory agent in animal models. The drug is administered orally or by injection.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Hydroxy-1,2,5-thiadiazole-3-carboxylic acid is a source of health and has been shown to be effective in the treatment of infectious diseases. It has long-term efficacy in the treatment of hepatitis C, which is a type of hepatitis caused by a virus. 4-Hydroxy-1,2,5-thiadiazole-3-carboxylic acid also has an anti-cancer effect on skin cancer cells. Chronic viral hepatitis is found worldwide and can lead to death. Hepatitis C is the most common type of chronic viral hepatitis with prevalence rates between 2% and 5%. Gallbladder cancer is also known as gallstones or cholelithiasis and causes symptoms such as abdominal pain in adults. Endoscopic ultrasound (EUS) helps detect gallstones by using sound waves to see inside the gallbladder for stones or other problems that may cause blockages.</p>

<p>Versatile small molecule scaffold</p>

<p>(1-Ethenyl-1H-imidazol-2-yl)methanol is a heterocyclic compound with a triazole ring. It is a cyclic imide that contains an imidazole ring and a methyl group, giving it the properties of an azide. The molecule yields hydroxymethyl groups and has been used in the synthesis of triazolyl compounds. This molecule can be prepared by reacting benzaldehyde with hydrochloric acid to form benzyl chloride, which is then reacted with ammonia to produce (1-ethenyl-1H-imidazol-2-yl)methanol. Heterocycles are molecules containing at least one heteroatom such as nitrogen, oxygen, or sulfur. They are often unsaturated rings or rings containing two or more different types of atoms and may be found in drugs or other organic compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Chloro-pyrimidin-2-yl)-methyl-amine is a kinase inhibitor that has been shown to have the ability to inhibit inflammation. It is an analog of 5-chloro-N-(1,3-dioxo-1,3,3a,4,5,6,7,8a-octahydroindeno[1′,2′:4′,5′]pyrazino[2′:1′]pyrimidin-4-yl)methanamine and encompasses a number of derivatives. These derivatives include prodrugs and alcohols that are activated by esterases or reduced by glutathione reductase. The inhibition of kinases reduces the production of inflammatory cytokines such as TNFα and IL6.</p>

<p>Piperidine is the simplest piperidine alkaloid. It is a white crystalline compound that has a peppermint-like odor and is soluble in water. Piperidine is found in plants such as annuum, tuberosum, and crassulaceae. It also occurs naturally in animal tissues and human urine. Piperidine can be used as an intermediate in the production of other drugs, such as sedamine, which is used to treat insomnia. Other drugs that contain piperidine include aminopyrine, aminopropylpiperazine, aminopropylpiperidone, amphetamine sulfate, benzoic acid methyl ester hydrochloride, benzoylacetanilide, benzylpiperazine citrate dihydrochloride monohydrate, chlorpheniramine maleate hydrate</p>

<p>1-(Aminomethyl)cycloheptanol (1ACHP) is a new chemical entity that is an antagonist of the azolylbenzamides. It is a metabolically stable, orally bioavailable, and penetrable inhibitor of the azolylbenzamide-induced hyperalgesia in animals. 1ACHP also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. The compound has been shown to have good metabolic stability, with only one metabolite detected in rat urine after oral administration.</p>

<p>Versatile small molecule scaffold</p>

<p>[(2-Chlorophenyl)amino]carbonitrile is a model complex that has been studied extensively for its ability to form coordination complexes with anion radicals. The compound was synthesized by reacting cyanamide and the desired chloroaromatic compound in acid conditions. This reaction is a one-step method that can be used to generate many different types of models, which may be reused after they are generated. [(2-Chlorophenyl)amino]carbonitrile has also been shown to react efficiently with molecular orbitals, making it a useful tool for understanding the effect of various functional groups on the stability of metal-containing complexes.</p>

<p>2,3-Dihydro-1H-isoindol-5-amine is a compound that is used in the production of codeine. The drug binds to opioid receptors in the brain and spinal cord, which brings about analgesic effects. It has been shown to have synergistic effects when combined with nitrous oxide or phenylbutazone. 2,3-Dihydro-1H-isoindol-5-amine can be administered intravenously or intramuscularly as an organic solution. The drug is insoluble in water and does not dissolve well in most organic solvents. Diagnosis of Alzheimer's disease can be done by quantifying the concentration of 2,3-Dihydro-1H-isoindol-5-amine in cerebrospinal fluid (CSF).</p>

<p>5-Iodo-1-methyluracil is a synthetic pyrimidine nucleoside that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by interacting with the enzyme thymidine kinase, which is required for the conversion of thymine to uracil. 5-Iodo-1-methyluracil also interacts with adenosine deaminase, which converts adenosine to inosine. The activated form of 5-Iodo-1-methyluracil can be transformed into cytotoxic compounds by metathesis reactions, such as those involving carbonyl groups or activated esters. This compound is often used in assays to detect hypervalent iodine compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>N-Cycloheptyl-N-ethylamine is a synthetic compound that has been shown to inhibit the tyrosine kinase enzyme. This inhibition prevents the transmission of signals from the receptor to the inside of the cell, which may be responsible for the reduction in inflammation, immunosuppression, and cancer. N-Cycloheptyl-N-ethylamine is being developed as an anti-inflammatory drug for use in autoimmune diseases and cardiovascular diseases. It also has been shown to have anti-cancer properties by inhibiting pyrimidine synthesis in cancer cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(2-Hydroxyethyl)azepan-2-one is a neutralizing reaction product of melamine and an amine. It is used as a corrosion inhibitor for coatings and in the production of aziridines, which are monomers that can be converted to amides or aldehydes. 1-(2-Hydroxyethyl)azepan-2-one is also used as an organic solvent.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Azatricyclo[6.3.1.0,4,12]dodeca-1(12),4,6,8,10-pentaene is a synthetic compound that has been shown to have antiviral properties and is being investigated as an agent for the treatment of inflammatory diseases. 2-Azatricyclo[6.3.1.0,4,12]dodeca-1(12),4,6,8,10-pentaene binds to bromodomains in the nucleus and prevents the virus from interacting with it by competitively inhibiting its binding site on the DNA strand. This prevents transcription of genes and therefore inhibits viral replication. The mechanism of action of 2-azatricyclo[6.3.1.0,4,12]dodeca-1(12),4,6,8,10-pentaene has not yet been elucidated</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-hydroxy-4,4-dimethylpyrrolidin-2-one is a dienophile that reacts with cyclopentadiene to produce a cycloadduct. It is an efficient catalyst for the production of polymers and acrylates from dienophiles. This compound can be used in a solid phase synthesis. 3-hydroxy-4,4-dimethylpyrrolidin-2-one has been shown to react with benzoic acid to produce n-substituted isoprenes. These interactions are important for nature as they are part of the biosynthesis of natural products such as hormones and vitamins.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(2-Oxopropyl)-2,3-dihydro-1H-indole-2,3-dione is a neutral compound that belongs to the class of ketones. It has been found to be decarboxylated in alkaline conditions and is oxidized by halomethyl radicals. The compound is also recyclized from isatin and reacts with phenols. 1-(2-Oxopropyl)-2,3-dihydro-1H-indole-2,3-dione has been found to form heterocyclic compounds when mixed with benzaldehyde and nitromethane.</p>

<p>2-Nitrobenzene-1-carbothioamide is a hydroxylamine derivative that inhibits the activity of degraders, such as nitrosoperoxycarbonic acid, which breaks down clots. It also has an inhibitory effect on the activity of clotting enzymes and sirtuin. The compound has been shown to be useful in diagnosis of cancer and other diseases. 2-Nitrobenzene-1-carbothioamide is used in conjunction with a radioactive isotope for diagnosis. It can be conjugated to diagnostic agents for use in imaging studies or it can be used as a reagent for the identification of proteins or nucleic acids. 2-Nitrobenzene-1-carbothioamide is also used as an organic solvent in diagnostic chemistry, due to its relatively low toxicity and high stability in organic solvents.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 5-(bromomethyl)-2-furoate is a polycyclic compound that has been shown to have activity against deacetylases. It is believed to work by binding to the catalytic site of the enzyme, thereby inhibiting acetylation reactions. This results in increased levels of histone acetylation and an improvement in cognition. Methyl 5-(bromomethyl)-2-furoate also has been shown to inhibit phosphodiesterases, which are enzymes that break down cyclic nucleotides in cells.END&gt;</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(2R,5R)-2,5-Dimethylpyrrolidine HCl ee is a chiral molecule that is the active form of 2,5-dimethypyrrolidine hydrochloride. It is a colorless solid with a melting point of 87 °C. The substance has the chemical formula C4H9NHCl and molecular weight of 206.75 g/mol. It can be classified as an asymmetric compound because it does not have an equal number of atoms on each side of its plane of symmetry. (2R,5R)-2,5-Dimethylpyrrolidine HCl ee has been shown to have antihypertensive properties in rats and rabbits. It also has been used for the treatment of essential tremor and Parkinson's disease. This drug is characterized by being flammable and soluble in ethanol and diethyl ether but insoluble in water. Recrystallized (2R,5R)-</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Furan-3-carbohydrazide is a gaseous molecule with an electron configuration of 5s2p3d1. This molecule has a molecular weight of 102.06 and refractivity of 1.5. Furan-3-carbohydrazide has two optical isomers, one with a dipole moment of 1.9 debye and the other with a dipole moment of 3.2 debye, as well as two different electronic structures: five-membered and six-membered. The five-membered electronic structure is more stable than the six-membered electronic structure because it has lower energy levels for the electrons in the orbitals. Furan-3-carbohydrazide is an exothermic molecule that can be synthesized by reacting pyrrole and thiourea in the presence of hydrazine hydrate.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6,8-dimethyl-3H,4H-imidazo[1,5-a][1,3,5]triazin-4-one is a cytotoxic compound that binds to chloride anions in the cell membrane and causes disruption of the ionic equilibrium. It also binds to human cells by coordinating with the anionic sites on the cell surface. This drug has been shown to inhibit growth and induce apoptosis in bladder cancer cells. 6,8-Dimethyl-3H,4H-imidazo[1,5-a][1,3,5]triazin-4-one also inhibits tumor growth in mice transplanted with human bladder cancer cells. The drug works by binding to DNA bases and causing crosslinking of DNA chains. This leads to inhibition of RNA synthesis and protein synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(Pyridin-3-ylmethyl)-amino]-ethanol is the methanol analogue of the coordination compound 2-[(pyridin-2-ylmethyl)-amino]-ethanol. The molecule has a chain structure, with two coordination bonds and a total of six atoms. It is a dimeric molecule that can be polymerized to form polymers. The structure is metallic with antiferromagnetic coupling between the two metal centers, which can be assembled into larger structures. This compound interacts with other molecules at the coordinated sites where it binds. Magnetism results from the unpaired electron spins on each metal center and from spin-spin interactions between these centers.</p>

<p>9-Ethyl-9H-carbazole-3,6-dicarbaldehyde (9ECDA) is a fluorescent molecule that has been shown to have anticholinesterase activity. This compound is being developed for the treatment of cervical cancer and other cancers. 9ECDA is synthesized by reacting 2,4,5,6-tetrafluorobenzaldehyde with excess ethyl acetoacetate in the presence of sodium methoxide. 9ECDA can be used as a fluorescent probe for the detection of anions in water. This compound also has optical properties that are dependent on its anion conjugation state. The fluorescence of 9ECDA is quenched when it binds to butyrylcholinesterase and other anionic binding sites.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>