Building Blocks

<p>Versatile small molecule scaffold</p>

<p>3-(Chloromethyl)-5-phenylisoxazole is a water soluble moiety that is used in the synthesis of conjugates with antitumor activity. 3-(Chloromethyl)-5-phenylisoxazole has been shown to inhibit the growth of brain tumors by binding to DNA, inhibiting transcription and replication. The drug also inhibits protein synthesis and cell division. This compound can be esterified and isothiazole substituted to form an antitumor drug that has a strong antiproliferative effect on human leukemia cells. The biological activity of 3-(chloromethyl)-5-phenylisoxazole can be enhanced by catalytic hydrogenation with methanol in acidic conditions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Methoxy-2-oxoethyl)benzoic acid is an organic compound that can be synthesized by the reaction of 2-methoxyacetophenone with lithium borohydride. It is also obtained as a byproduct in the synthesis of other organic compounds, such as esters and anhydrides. The chloride group of 2-(2-methoxy-2-oxoethyl)benzoic acid can be replaced with other groups to produce homophthalic, acetyl, or anhydride derivatives. 2-(2-Methoxy-2-oxoethyl)benzoic acid is often used as a starting material for the synthesis of cyclic esters and alcohols. It has been used in the synthesis of drugs such as dipyridamole and dapsone.</p>

<p>2-Amino-5-phenyl-3-furonitrile is a heterocyclic compound that belongs to the group of pyrimidine derivatives. It can be prepared by the reaction of 2,4,6-trichloropyrimidine with phenylacetonitrile and sodium hydroxide in water. This synthesis gives high yields of 2-amino-5-phenyl-3-furonitrile. The compound reacts with isothiocyanates to form heterocyclic compounds. The process of catalyzed heterocyclization has been shown to be effective for the synthesis of pyrimidine derivatives.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Formylfuran-3-carboxylic acid is a furan derivative with an oxidation product that has been shown to be useful as a peroxide scavenger. It is synthesized by the reaction of 2-formylphenol and formaldehyde in the presence of copper salts. The molecular modelling studies revealed that this compound consists of a five membered ring with an oxygen atom at its centre, which is flanked by two carbon atoms at each side. The carboxylic acid group (-COOH) is on one end and the hydroxymethyl group (-CHOH) on the other end. The molecule also has a carbonyl group (-C=O) and a methylene bridge (-CH2-) between the two carbon atoms. This compound has been found to have efficient antioxidant properties when it reacts with reactive oxygen species (ROS). It was also found to have antioxidative activities when it reacts with ROS produced by galacturonic acid and fur</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>