Amines

<p>Applications 1-(2-Phenylethynyl)cyclohexanamine is a reactant that functions as a catalyst in the cyclization of propargylamines.<br>References Zhao, D. et al.: ChemCatChem., 9, 4598 (2017); Yuan, R. et al.: J. Org. Chem., 82, 3639 (2017);<br></p>

<p>Stability Hygroscopic<br>Applications 2-(2,5-diaminophenyl)ethanol Sulfate (cas# 93841-25-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Amino-1,3-benzenedisulfonic Acid is used as a reagent in the synthesis of arylazopyridoxal phosphate and phosphonate derivatives as P2 receptor antagonists.<br>References Kim, Y., et al.: Drug Develop. Res., 45, 52 (1998)<br></p>

<p>Applications Ethyl trans-2-(4-aminocyclohexyl)acetate, HCl<br></p>

<p>Applications (E)-N-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)-4-oxo-4-phenylbut-2-enamide is a useful research chemical.<br></p>

<p>Applications 2-(4-Aminophenyl)propanoic acid is a reagent in the preparation of 3-aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents (Erratum).<br>References Pevarello, P., et al.: J. Med. Chem., 48, 5058 (2005);<br></p>

<p>Applications 4-Nitro-1,3-diaminobenzene is a general chemical reagent used in the synthesis of pharmaceuticals. Used in the synthesis of potent and selective Chk-1 inhibitors in the treatment of various cancers.<br>References Wang, L. et al.: J. Med. Chem., 50, 4162 (2007);<br></p>

<p>Applications Ethyl 4-amino-3-fluorobenzoate<br></p>

<p>Applications 2-Aminobenzeneboronic acid pinacol ester is a reagent used to synthesize regiospecific quinolines. It can also be used to synthesize (±)-Epimeloscine and (±)-Meloscine.<br>References Zhang, H., et al.: J. Am. Chem. Soc. 133, 10376 (2011); Horn, J., et al.: Org. Lett 10, 4117 (2008)<br></p>

<p>Applications N,N'-Diaminoguanidine Monohydrochloride is an analyte for HPLC. It also functions as an intermediate for the synthesis of energetic salts or materials based on dinitroguanidine.<br>References Shen, K., et al.: Huaxue Gongye Yu Gongcheng Jishu, 35, 74 (2014); Hu, B., et al.: Aust. J. Chem., 67, 1037 (2014); Zhang, Y., et al.: Chem. - A Eur. J., 18, 987 (2012)<br></p>

<p>Applications Methyl 4-aminosalicylate<br></p>

<p>Stability Light Sensitive<br>Applications A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aslan, K., et al.: J. Fluoresc., 14, 391 (2004), Gole, A., et al.: Langmuir, 20, 7117 (2004), Cavalcante, A., et al.: Biochem. Eng. J., 29, 258 (2006),<br></p>

<p>Applications 2-Dimethylaminoethyl Benzilate is an intermediate in the synthesis of Propinox (P771500), an antispasmodic agent used in the treatment of moderate to severe colic pain of biliary origin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mishra, R., et al.: Pharma. Chemica., 2, 185 (2010);<br></p>

<p>Applications 4-(4-Aminophenoxy)benzonitrile<br></p>

<p>Stability Volatile<br>Applications 2-Furfurylamine is used in the synthesis of 2-Amino-N-(2-furylmethyl)propanamide, as a novel alanylglycine equivalent synthesized by bacilysin synthetase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mah, R., et al.: Appl. Microbiol., 15, 866 (1967), Faber, K., et al.: Pure Appl. Chem., 69, 1613 (1997), Marahiel, M., et al.: Chem. Biol. 4, 561 (1997),<br></p>

<p>Applications Dimethylamine (40% aq.) is a compound often used in industry as a precursor to Nitrosodimethylamine (N525625), a potent carcinogen that is produced during disinfection of wastewater effluent, and is also present in trace amounts in food and polluted air. Dimethylamine is also present in human urine and can be indicative of certain disorders.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gereke, A. &amp; Sedlak, D.: Env. Sci. Tech., 37, 1331 (2003); Mitch, W., et al.: Env. Eng. Sci., 20, 389 (2003); Tsikas, D., et al.: J. Chromatogr. B, 851, 229 (2007)<br></p>

<p>Applications 5-Aminoboronphthalide is used as a reactant in the preparation of 2,1-benzoxaborole peptide isoquinoline derivatives as HCV NS3 protease inhibitors. It is also used as reactant in the synthesis of nanocarrier for chemomechanically driven guest delivery fueled by intracellular ATP.<br>References Li, X., et al.: Bioorg. Med. Chem. Lett., 21, 2048 (2011); Biswas, S., et al.: Nat. Chem., 5, 613 (2013);<br></p>

<p>Applications Cyclopentylamine is a useful synthetic intermediate. It was used to prepare chiral N-aminoacyl pyrrolidines and (adamantylamino)acetamides as selective and orally bioavailable dipeptidyl peptidase IV inhibitors with antihyperglycemic properties. It is also a reagent used to prepare dipeptidyl peptidase IV inhibitors as potent anti-diabetic agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Villhauer, E., et al.: J. Med. Chem., 46, 2774 (2003); Ahn, J., et al.: Bioorg. Med. Chem. Lett., 14, 4461 (2004)<br></p>

<p>Applications 2-[(Dipropylamino)sulfonyl]benzoic Acid, is a building block used in various chemical synthesis.<br></p>

<p>Stability Air Sensitive<br>Applications 4-(2-Aminoethyl)morpholine is used as a reagent in the synthesis of novel quinoxaline-5-carboxamide derivatives which have antibacterial activity. Also used as a reagent in the synthesis of pyrazol-4-ylpyrimidine derivatives as potential ROS1 kinase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Srinivas, K., et al.: J. Appl. Chem., 3, 1432 (2014); Abdelazem, A.Z., et al.: Eur. J. Med. Chem., 90, 195 (2015)<br></p>

<p>Applications 2-Amino-5-formylthiazole is a useful reagent for the preparation of cationic azo dyes.<br>References Salvador, M. A., et al.: Dyes and Pigments, 82, 118 (2009); Salvador, M. A., et al.: Tetrahedron, 64, 299 (2008)<br></p>

<p>Applications ETHYL 4-AMINO-2-FLUOROBENZOATE (cas# 73792-06-0) is a useful research chemical.<br></p>

<p>Applications 4-Aminophenethyl Alcohol, is a building block that can be used in the synthesis of various compounds, such as in synthesis of 4-aminostyrene, and in functionalization of graphene nanoplatelets.<br>References Li L, et al.Polymer Journal 33(4), 364-370; Hagiwara T, et al. Macromolecules 24(26), 6856-6858, (1991);<br></p>

<p>Applications N-[(2,4-Difluorophenyl)methylene]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D450850), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.<br>References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)<br></p>

<p>Applications 1,4-Phenylenediamine-13N2 is the isotope labelled analogue of 1,4-Phenylenediamine (P319845), an organic compound that is a derivative of aniline and a main ingredient for the production of polymers and hair dyes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chugh, K., et al.: J. Med., 13, 131 (1982), Baud, F., et al.: J. Toxicol. Med., 4, 279 (1984), Ashraf, W., et al.: Human Exp. Toxicol., 13, 167 (1994),<br></p>

<p>Applications TERT-BUTYL N-(DIAMINOMETHYLIDENE)CARBAMATE (cas# 219511-71-4) is a useful research chemical.<br></p>

<p>Applications 2-Aminomethyl-1,4-benzodioxane is used in the synthesis of N-substituted (dihydrobenzodioxinyl)methylamine derivatives as D2 antagonists/5-HT1A partial agonists with potential as atypical antipsychotic agents in relation to affinity for α1 adrenoceptors.<br>References Birch, A. M., et al.: J. Med. Chem., 42, 3342 (1999);<br></p>

<p>Applications A polyethyleneglycol (PEG) derivative used in the preparation of single cell optical biosensors.<br>References Kilian, K. et al.: Nano Lett., 9, 2021 (2009); Kilian, K. et al.: Proc. SPIE, 7397, 739703 (2009);<br></p>

<p>Applications Used in the preparation of (R)-Sulforaphane (S699105).<br></p>

<p>Applications (1S,3R,4S)-Ethyl 4-Amino-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate Oxalate has been used as a reactant for the preparation of oxadiazole compounds containing cyclohexanediamine moiety.<br></p>

<p>Applications ethyl 4-aminopentanoate hydrochloride (cas# 119396-97-3) is a useful research chemical.<br></p>

<p>Applications 2-Amino-5,6-dihydro-4h-benzothiazol-7-one<br></p>

<p>Applications 2-[6-(Acetylphenylamino)-1,3,5-hexatrienyl]-1,1-dimethyl-3-sulfobutyl-1H=-benz[e]indolium Inner Salt is a reactant used in the preparation of indocyanine green as an infrared probe.<br>References Suganami, A. et al.: Bioorg. Med. Chem. Lett., 22, 7481 (2012); Doi, T. et al.: Synlett., 23, 306 (2012);<br></p>

<p>Applications pentan-2-amine hydrochloride (cas# 76716-21-7) is a useful research chemical.<br></p>

<p>Applications 3-Aminocyclohexanol_x000D_(cis/trans mixture) (cas# 6850-39-1) is a compound useful in organic synthesis.<br></p>

<p>Applications It can be used in the preparation of sanitizer for use in factories.<br>References Yuan, H., et al.: Sanitizer used in factory and preparation method thereof, CN 106038470 (2016)<br></p>

<p>Applications 2-amino-6-hydroxybenzoic acid (cas# 567-62-4) is a useful research chemical.<br></p>

<p>Applications 2-(bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid (cas# 171557-31-6) is a useful research chemical.<br></p>

<p>Applications N-(furan-3-ylmethyl)cyclohexanamine (cas# 462068-58-2) is a useful research chemical.<br></p>

<p>Applications 6-Aminohexanenitrile (cas# 2432-74-8) is a compound useful in organic synthesis.<br></p>

<p>Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.<br>References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)<br></p>

<p>Applications 3-Amino-2-(formylamino)-3-iminopropanamide is a Temozolomide (T017775) impurity. Temozolomide acts as a imidazotetrazine alkylating agent. An antineoplastic.<br>References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997), Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999), Hait, W., et al.: Cancer Res., 69, 1263 (2009),<br></p>

<p>Applications Azido-PEG1-amine (cas# 464190-91-8) is a useful research chemical.<br></p>

<p>Applications Methyl 4-amino-2-fluorobenzoate<br></p>

<p>Applications 3-(N,N-Dimethylamino)phenylboronic Acid (cas# 178752-79-9) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-phenylcyclohexanamine (cas# 19992-45-1) is a useful research chemical.<br></p>

<p>Applications DL-3-aminoisobutyric acid hydrate is a useful research chemical for organic synthesis and other chemical processes.<br>References Saito, N., et al.: Bunseki Kagaku, 63, 909 (2014)<br></p>

<p>Applications 3-[benzyl(methyl)amino]propane-1,2-diol (cas# 60278-98-0) is a useful research chemical.<br></p>

<p>Applications n-Dipropylamine is a useful reagent for the preparation of perylene derivatives for photosensitive fluorescent resins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jang, H., et al.: PCT Int. Appl. (2021), WO 2021010703 A1<br></p>