Amines

<p>Applications 5-Aminoboronphthalide is used as a reactant in the preparation of 2,1-benzoxaborole peptide isoquinoline derivatives as HCV NS3 protease inhibitors. It is also used as reactant in the synthesis of nanocarrier for chemomechanically driven guest delivery fueled by intracellular ATP.<br>References Li, X., et al.: Bioorg. Med. Chem. Lett., 21, 2048 (2011); Biswas, S., et al.: Nat. Chem., 5, 613 (2013);<br></p>

<p>Applications 2-(4-Aminophenyl)propanoic acid is a reagent in the preparation of 3-aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents (Erratum).<br>References Pevarello, P., et al.: J. Med. Chem., 48, 5058 (2005);<br></p>

<p>Applications (E)-N-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)-4-oxo-4-phenylbut-2-enamide is a useful research chemical.<br></p>

<p>Applications Ammonium Carbonate Carbamate is used in the study of amino acids and has important implications in biochemical studies.<br>References Nanping, W. et al.: J. Phys. Chem., 99, 359 (1995);<br></p>

<p>Applications n-Dipropylamine is a useful reagent for the preparation of perylene derivatives for photosensitive fluorescent resins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jang, H., et al.: PCT Int. Appl. (2021), WO 2021010703 A1<br></p>

<p>Applications Ethyl (1S,3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxycyclohexane-1-carboxylate, is a building block used in various chemicla synthesis. It can be used for the preparation of six stereoisomers of diaminocyclohexane carboxamide as key intermediates for synthesis of factor Xa inhibitors.<br>References Wang, X. et al.: Tetrahedron, Vol.73, Iss.11, P1381-1388 (2017);<br></p>

<p>Applications 4-Amino-1,1,3-trimethylindane is used as a reagent in the synthesis of (difluoromethylnicotinic)indanyl carboxamides as fungicides useful in crop protection.<br>References Maechling, S., et al.: PCT Int. Appl. WO 2014095675 A1 20140626. Jun 26, 2014<br></p>

<p>Applications 2-(6-Aminopurin-9-yl)ethanol is a useful intermediate in the preparation of aryloxyalkyl derivatives of adenine with antiviral activity.<br>References Petrov, V. I., et al.: Chemistry of Heterocyclic Compounds, 39, 1218 (2003)<br></p>

<p>Applications 3,4-Dimethoxybenzylamine (cas# 5763-61-1) is a compound useful in organic synthesis.<br></p>

<p>Applications [4-[3-[[(Methylamino)methylene]amino]phenyl]-2-thiazolyl] Guanidine is a guanidino heterocyclic phenylamidines with pharmaceutical properties.<br>References Bietti, G., et al.: Eur. Pat. Appl. (1983), EP 89730 A2 19830928<br></p>

<p>Applications N,N-Dimethyl-p-phenylenediamine (DMPD) has been used to n-dope bilayer graphene (BG) along with p-dope of tetracyanoethylene bilayer graphene to increase the band gap of DMPD/BG. N,N-Dimethyl-p-phenylenediamine (DMPD) has been shown to inhibit corrosion of mild steel in a sulphuric acid medium.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, T.H., et. al.: J. Phys. Chem. C., 117, 12873 (2013); Singh, K.U., Dubey, R.S.: Int. J. Chem., 1, 366 (2012)<br></p>

<p>Applications 2-Aminobenzenesulphonic acid (cas# 88-21-1) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-(3-Butyn-1-yl)-3H-diazirine-3-ethanamine can be used as reactant/reagent in minimalist cyclopropene-containing photo-cross-linkers suitable for live-cell imaging and affinity-based protein labeling.<br>References Li, Z., et al.: J Am Chem Soc, 136, 9990 (2014)<br></p>

<p>Applications 3-[(Dimethylamino)carbonyl]phenol can be used in the synthesis of novel purine and bicyclic pyrimidine, which are factor Xa inhibitors, and also have high selectivity over thrombin and trypsin.<br>References Buckman B. O., et al.: Bio. Med. Chem. Let., 8, 2235 (1998)<br></p>

<p>Applications Cyclopent-3-enamine hydrochloride (cas# 91469-55-5) is a useful research chemical.<br></p>

<p>Applications 5-Amino-1,2,3-thiadiazole, as a thiadiazole derivative, is a privileged structure in medicinal chemistry and has been investigated for anticonvulsant and antimicrobial activities.<br>References Matsumoto, T., et al.: Masakuni; PCT Int. Appl. (2006), WO 2006054652 A1 20060526; Gommaa, A., et al.: Alexandria J. Pharm. Sci., 5, 153 (1991)<br></p>

<p>Stability Air Sensitive<br>Applications 4-(2-Aminoethyl)morpholine is used as a reagent in the synthesis of novel quinoxaline-5-carboxamide derivatives which have antibacterial activity. Also used as a reagent in the synthesis of pyrazol-4-ylpyrimidine derivatives as potential ROS1 kinase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Srinivas, K., et al.: J. Appl. Chem., 3, 1432 (2014); Abdelazem, A.Z., et al.: Eur. J. Med. Chem., 90, 195 (2015)<br></p>

<p>Applications 5-(Aminomethyl)furan-2-carboxylic Acid Hydrochloride is a useful reagent in the preparation of novel heteroaromatic substrates of GABA aminotransferase.<br>References Hawker, D. D., et al.: Bioorg. Med. Chem., 20, 5763 (2012)<br></p>

<p>Stability Temperature Sensitive<br>Applications A reagent which releases Nitric Oxide into aqueous solutions at controlled rates for in vitro studies.<br></p>

<p>Applications Methyl 4-amino-2,3,5,6-tetrafluorobenzoate (cas# 715-37-7) is a useful research chemical.<br></p>

<p>Stability Store in freezer at -20°C<br>Applications A synthetic intermediate<br></p>

<p>Applications 3-Aminomethylbenzoic acid<br></p>

<p>Applications 2,5-Dihydroxybenzoic Acid Butylamine Salt [Matrix for MALDI-TOF/MS] (cas# 666174-80-7) is a useful research chemical.<br></p>

<p>Applications (1S,2S)-1,2-Diphenyl-1,2-ethanediamine (cas# 29841-69-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid is an intermediate used in the synthesis of ent-Abacavir (A105015), which is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br></p>

<p>Applications 4-(4-Aminophenoxy)benzonitrile<br></p>

<p>Applications 2-(4-Amino-2-ethoxyphenyl)pthalimide (cas# 106981-52-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Trimethylphenylammonium Iodide (cas# 98-04-4) is a compound useful in organic synthesis.<br>References Dorweiler, J., et al.: Biochem., 42, 14653 (2003),<br></p>

<p>Applications 3-(N,N-Dimethylamino)phenylboronic Acid (cas# 178752-79-9) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Light Sensitive<br>Applications A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aslan, K., et al.: J. Fluoresc., 14, 391 (2004), Gole, A., et al.: Langmuir, 20, 7117 (2004), Cavalcante, A., et al.: Biochem. Eng. J., 29, 258 (2006),<br></p>

<p>Applications (s)-2-phenyl-1-propanamine (cas# 17596-79-1) is a useful research chemical.<br></p>

<p>Stability Air Sensitive<br>Applications Aminophenethylamine is an efficient sorbent for the separation of dopamine.<br>References Lulinski, P., et al.: Talanta, 119, 623 (2014)<br></p>

<p>Applications N-Carbobenzoxy-1,4-diaminobutane HCl is used in the synthetic preparation of pyrazolyl glucopyranoside and galactopyranoside derivative inhibitors of human sodium-glucose cotransporter 1 (SGLT1) for preventives or therapeutics for diseases related to hyperglycemia or galactosemia.<br>References Teranishi, H.; et al.: PCT Int. Appl. 215 pp. Patent 2004 CODEN:PIXXD2<br></p>

<p>Applications A reactant used in the preparation of (-)-Amathaspiramide F.<br>References Sakaguchi, K. et al.: Tetrahedron, 65, 10355 (2009); Sakaguchi, K. et al.: Org. Lett., 10, 5449 (2008)<br></p>

<p>Applications N,N'-Diaminoguanidine Monohydrochloride is an analyte for HPLC. It also functions as an intermediate for the synthesis of energetic salts or materials based on dinitroguanidine.<br>References Shen, K., et al.: Huaxue Gongye Yu Gongcheng Jishu, 35, 74 (2014); Hu, B., et al.: Aust. J. Chem., 67, 1037 (2014); Zhang, Y., et al.: Chem. - A Eur. J., 18, 987 (2012)<br></p>

<p>Impurity Tiamulin Hydrogen Fumarate Impurity C<br>Applications Reagent used in the addition of Thiobistriethylamine.<br>References Evers, M., et al.: Bioorg. Med. Chem. Lett., 13, 4415 (2003),<br></p>

<p>Applications BENZO[D]THIAZOL-4-AMINE (cas# 1123-51-9) is a useful research chemical.<br></p>

<p>Applications 6-AMINO-2,2-DIMETHYL-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE (cas# 105807-84-9) is a useful research chemical.<br></p>

<p>Applications N-Ethyl-2,4-dichlorobenzylamine<br></p>

<p>Applications 2-(3-Aminopropylamino)ethanol is the hydroxy analogue of WR-1065 (A576820), a metabolite of Amifostine (A576810). Amifostine is an organic thiophosphate that has the ability to protect a broad range of tissues from cytotoxicity (e.g. from chemotherapeutic agents) without inducing an antitumour response. 2-(3-Aminopropylamino)ethanol is also used as an nucleophilic tag in the detection of human butyrylcholinesterase adducts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Antonadou, D., et al.: Int. J. Rad. Oncol. Biol. Phys., 52, 739 (2002); Kemp, G., et al.: J. Clin. Oncol., 14, 2101 (1996)<br></p>

<p>Applications 3-[(3-aminophenyl)amino]benzonitrile (cas# 1147094-81-2) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br></p>

<p>Applications 6-​Amino-​5-​nitrochromen-​2-​one is a reagent used in the synthesis of pyranopyridinediones.<br>References Khan, M. et al.: J. Pure App. Sci., 22, 37 (2004);<br></p>

<p>Stability Volatile<br>Applications In the presence of sugars, lysine, similarly to asparagine and phenylalanine, can undergo carbonyl-assisted decarboxylative deamination reaction to generate pent-4-en-1-amine, the counterpart of acrylamide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stadler, R., et al.: Chem. Res. Toxicol., 16, 1242 (2003), Stadler, R., et al.: J. Agric. Food Chem., 52, 5550 (2004),<br></p>

<p>Applications N-(Benzyloxycarbonyl)ethylenediamine Hydrochloride is a reagent used to synthesize new opioid ligand as an analgesics with mixed agonist and antagonist properties to induce tolerance and dependence.<br>References Salvadori, S., et al.: Bioorg. Med. Chem., 15, 6876-6881 (2007);<br></p>

<p>Applications 4-(Methylamino)benzoic Acid (cas# 10541-83-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(Tributylstannyl)-2-propen-1-amine (cas# 155258-22-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl 2-Aminothioazole-4-carboxylate (cas# 118452-04-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(3-Aminophenyl)ethanol is a useful compound for the synthesis of indolines and dihydrobenzofurans via iron and copper-catalyzed iodination and cyclization.<br>References Henry, M. C., et al.: J. Org. Chem., 84, 346 (2019)<br></p>

<p>Applications 4-(Aminomethyl)-Cyclohexanecarboxylic Acid (cas# 701-54-2) is a useful research chemical.<br></p>

<p>Applications Used in the preparation of pyrimidine derivatives.<br></p>