Amines

<p>Applications 5,6-Diaminouracil sulfate is an intermediate in the synthesis of Paraxanthine (P192500) and Paraxanthine analogs.<br>References Mueller, C.E., et al.: J. Med. Chem., 36, 3341 (1993),<br></p>

<p>Applications (E)-N-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)-4-oxo-4-phenylbut-2-enamide is a useful research chemical.<br></p>

<p>Applications o-Chloramine T (cas# 110076-44-3) is a useful research chemical.<br></p>

<p>Applications Ethyl (Z)-3-(Dimethylcarbamoylamino)-4,4,4-trifluoro-but-2-enoate is an intermediate in the synthesis of Tiafenacil (T436300), which is a uracil herbicide used as a pesticide for the prevention and control of plants.<br>References Peng, X., et al. Faming Zhuanli Shenqing, 68pp Patent 2018 CODEN:CNXXEV<br></p>

<p>Applications (2S,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol is an enantiomer of (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol (A577286), which an intermediate used in the synthesis of S-adenosylhomocysteine analogs with biological activities.<br>References Lawrence, F., et al.: Biochem. S-Adenosylmethionine Relat. Compd., Proc. Conf., 637 (1982); Shire, D., et al.: Nucleosides &amp; Nucleotides, 2, 21 (1983)<br></p>

<p>Applications 2-Amino-5,5-dimethyl-5,6-dihydro-4h-benzothiazol-7-one<br></p>

<p>Applications N-Ethyl-N-butan-4-ol-nitrosamine can be used to study lack of tumorigenic effects on rat renal pelvic transitional epithelium of life-​span exposure to low doses of a bladder carcinogen<br>References Shibata, M.A., et.al.: J. Toxicol. Pathol., 6, 47-53, (1993);<br></p>

<p>Applications Ethyl 2-Dimethylaminomethylene-3-oxobutanoate (cas# 51145-57-4) is a compound useful in organic synthesis.<br></p>

<p>Applications methyl amino(2-bromophenyl)acetate hydrochloride (cas# 1219408-44-2) is a useful research chemical.<br></p>

<p>Applications Ethyl 4-[[(methylphenylamino)methylene]amino]benzoate<br></p>

<p>Applications 2-Amino-4,5-dimethylthiophene-3-carbonitrile is a useful research chemical for organic synthesis and other chemical processes.<br>References Rahman, K. M. M., et al.: Pakistan J. Sci. Ind. Res., 46, 95 (2003); Madhavi, K., et al.: Res. J. Pharm. Biol. Chem. Sci., 8, 387 (2017)<br></p>

<p>Applications Methyl 2-Amino-3,4,5-trimethoxybenzoate could be a constituent contributing to the aroma of green tea leaves.<br>References Hasegawa, T., et al.: J. Food Eng., 4, 10 (2014)<br></p>

<p>Applications Tris(N,N-dimethylaminopropyl)amine has been used in the synthesis of nickel(II) and cobalt(II) complexes with the propylene-bridged tripod ligand tris(3-dimethylaminopropyl)amine (donor set N4).<br>References Morassi, R., Dei, A.: J. Chem. Soc., 12, 2024 (1971)<br></p>

<p>Applications 2-(Tributylstannyl)-2-propen-1-amine (cas# 155258-22-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Cyclopentylmethanamine<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications ethyl (4-aminophenyl)carbamate (cas# 57399-97-0) is a useful research chemical.<br></p>

<p>Applications cyclopent-2-en-1-amine hydrochloride (cas# 91469-54-4) is a useful research chemical.<br></p>

<p>Applications 5-chloro-2,1,3-benzoxadiazol-4-amine (cas# 80277-04-9) is a useful research chemical.<br></p>

<p>Applications (benzyloxy)(methyl)amine (cas# 22513-22-0) is a useful research chemical.<br></p>

<p>Applications 3-(Cyclopropylaminocarbonyl)phenylboronic acid<br></p>

<p>Applications 4-(3-aminopropyl)-N,N-dimethylaniline (cas# 112103-97-6) is a useful research chemical.<br></p>

<p>Applications 2-((tert-bButoxycarbonyl)amino)-2-(hydroxymethyl)-4-(4-octylphenyl)butyl Acetate is the intermediate in the synthesis of Mono-O-acetyl Fingolimod TFA (F524600), which is an impurity of Fingolimod (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs.<br>References Brinkmann, V., et al.: Transplantation, 72, 764 (2001). Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002). Mtaloubian, M., et al.: Nature, 427, 355 (2004)<br></p>

<p>Applications 4-amino-3-hydroxybenzenesulfonamide (cas# 3588-76-9) is a useful research chemical.<br></p>

<p>Applications (1S,2S)-1,2-Diphenyl-1,2-ethanediamine (cas# 29841-69-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Tetramethylammonium Hydroxide is used to prepare a new family of silicate/aluminosilicate mesoporous molecular sieves.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Beck, J., et al.: J. Am. Chem. Soc., 114, 10834 (1992).<br></p>

<p>Applications Methyl (2S)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoate<br></p>

<p>Applications 2-Amino-6-oxo-4,5,6,7-tetrahydrobenzothiazole, is an intermediate in the synthesis of pharmaceutical and biologically active compounds including therapeutic agents. It is an intermediate for the synthesis of Pramipexole (P700755).<br>References Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)<br></p>

<p>Applications N-(p-Fluorophenyl)-hydroxylamine, is a reactant used in various chemical synthesis, such as in preparation of spiro-isoxazoline and spiro-isoxazolidine derivatives of tomentosin.<br>References Zaki, M., et al.: RSC Advances, Vol. 7, Iss 11, P: 6523-6529 (2017);<br></p>

<p>Stability Hygroscopic<br>Applications Cyclobutylmethylamine Hydrochloride<br></p>

<p>Applications 6-(4-Phenylbutoxy)-1-hexanamine is an intermediate in the synthesis of salmeterol (S090100), a structural analog of Albuterol (A514500).<br>References Goswami, J., et al.: Tetrahedron. Asym., 12, 3343 (2002);<br></p>

<p>Applications tert-Butyl 2-(3-Aminophenyl)acetate can be used as anti-heparanase to treat diseases and disorders associated with heparanase activity.<br>References Giannini, G., et.al.: PCT Int. Appl., 103, (2018);<br></p>

<p>Applications Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is used in the preparation of dendronized polymers. Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine can be used in the synthesis of optically degradable dendrons for temporary adhesion of proteins to DNA. It is also used in the preparation of tricylic polyamide receptor for carbohydrate recognition.<br>References Calderon, M. et al.: Macromol. Sym., 258, 53 (2007); Kostiainen, M.A. et al.: Chem. Eur. J., 16, 6912 (2010); Klein, E. et al.: Angew. Chem. Int. Ed., 44, 298 (2005);<br></p>

<p>Applications 2,4,6-Trimethyl-1,3-benzenediamine is a compound used in the synthesis of various polymers.<br>References Fritsch, D., et al.: Macromolec. Chem. Phys., 197, 701 (1996)<br></p>

<p>Applications Ammonium Bromide is used as a bromide activated chloramine biocide for effective control of volatile fatty acids and catalase and biofilm elimination in paper making industry. Also applied in biopharmaceuticals and dosage form designs.<br>References Bharati, S., et al.: Appita J., 56, 426 92003); Torosian, G., et al.: Am. J. Hosp. Pharm., 30, 716 (1973)<br></p>

<p>Applications Bis(4-diethylaminophenyl)methanol (cas# 134-91-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications S-(3-((4-Aminophenyl)amino)-3-oxopropyl) Methanesulfonothioate is an intermediate used in the synthesis of (E)-S-(3-((4-((4-(4-hydroxybutyl)phenyl)diazenyl)phenyl)amino)-3-oxopropyl) methanesulfonothioate (H895230), which a useful research chemical.<br></p>

<p>Applications S-(+)-2-Amino-1-propanol is an aliphatic amino alcohol shown to induce an antiproliferative effect in B16 melanoma cells. S-(+)-2-Amino-1-propanol is used in the preparation of oxazolines which are often used as ligands in homogeneous catalysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Landau, O. et al.: Cancer Lett., 69, 203 (1993); Gant, T.G. et al.: Tetrahedron, 50, 2297 (1994);<br></p>

<p>Applications Tetramethylammonium Chloride is used as a reagent in the synthesis of β-Triglycidyl Isocyanurate (T793805); a crosslinker and neoplasm inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vargha, V., et al.: J. Therm. Anal. Calorim., 83, 199 (2006); Spreafico, F., et al.: Cancer Chemoth. Pharm., 5, 103 (1980)<br></p>

<p>Applications 6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiproliferative and antimigratory activity. Behery, F<br>References Doleckova, I. et al.: Eur. J. Med. Chem., 62, 443 (2013); Behery, F. et al.: Eur. J. Med. Chem., 59, 329 (2013);<br></p>

<p>Applications N-(4-Bromophenyl)-[1,1-biphenyl]-4-amine is a useful reagent for preparing carbazole and dibenzofuran-linked tertiary arylamine compounds, which may improve electroluminescent properties.<br>References Ito, H., et al.: Jpn. Kokai Tokkyo Koho (2020), JP 2020093979 A<br></p>

<p>Applications 3-Amino-3-(3-(p-tolyloxy)phenyl)propanoic Acid is a useful chemical reagent.<br></p>

<p>Applications 3-Aminomethylbenzoic acid<br></p>

<p>Applications Ethyl 2-(2-Aminothiazol-4-yl)glyoxylate is used in the synthesis of antibacterial compounds. Also used in the synthesis of antiallergic and antiinflammatory agents, as glycolic amide derivatives.<br>References Takasugi, H. et al.: J. Antibio., 36, 846 (1983); Ban, M. et al.: Bioorg. Med. Chem., 6, 1069 (1998);<br></p>

<p>Applications 2-Aminobenzenesulphonic acid (cas# 88-21-1) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Azidobutylamine is weakly or non-mutagenic to Salmonella typhimurium.<br>References Owais, W.M., et. al.: Mutat. Res. Genetic Toxicol. Testing, 118, 229 (1983)<br></p>

<p>Applications 3-[benzyl(methyl)amino]propane-1,2-diol (cas# 60278-98-0) is a useful research chemical.<br></p>

<p>Applications 2-Benzylthio-5-amino-1,3,4-thiadiazole is used to study and investigate its antitumor activities against human cervix adenocarcinoma(HeLa), human liver cancer cell(SMMC-7721), human breast cancer cell(MCF-7) and human lung cancer cell(A549) lines that isfurther evaluated by CCK-8 assay.<br>References Zhao, J., et. al., Chem. Res. Chin. Univ.,30, 764-769 (2014)<br></p>

<p>Applications 4-phenylcyclohexanamine (cas# 19992-45-1) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 5-Methylbenzotriazole intermediate.<br>References Vitale, G., et al.: Med. Chem., 5, 507 (2009), El-Sharief, A., et al.: Eur. J. Med. Chem., 44, 4315 (2009), Potter, A., et al.: Bioorg. Med. Chem. Lett., 20, 586 (2010),<br></p>

<p>Applications N10-(Ethoxycarbonyl)tryptamine is an intermediate in the synthesis of N-Methyltryptamine-d3 (M331922), which is a labeled N-Methyltryptamine, a N-monomethylated derivative of tryptamine. N-Methyltryptamine, unlike its unmethylated counterpart, does not produce any psychoactive effects. High levels of N-Methyltryptamine have been found in cisternal cerebrospinal fluid of patients with acute paranoid schizophrenia.<br>References Schmid, C. et al.: J. Neurosci., 30, 13513 (2010); Uebelhack, R. et al.: Biomed. Biochim. Acta, 42, 1343 (1983);<br></p>

<p>Applications 3-​[[[3-​(Aminomethyl)​-​5-​methyl-​1-​oxohexyl]​amino]​methyl]​-​5-​methyl-hexanoic Acid is an intermediate in synthesizing 4,9-Diisobutyl-1,6-diazecane-2,7-dione (D456300), an impurity of rac-Pregabalin (P704800) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>

<p>Applications In mammals, metabolism of 3-aminopropionitrile leads to release of cyanide ions. Metabolic activity is localized in the microsomal fraction of the liver, and is believed to proceed through a free-radical pathway.<br>References Fernandez, G., et al.: Vet. Human Toxicol., 33, 321 (1991)<br></p>

<p>Applications (S)-2-Amino-3-(4-aminophenyl)propan-1-ol is derived from (2S)-2-Amino-3-(4-nitrophenyl)-1-propanol (A618365), which can be used as an intermediate in the synthesis of various pharmaceutical compounds. It is used in the preparation of a new series of 2-substituted thiazole carboxamides as potent inhibitors of Akt kinases.<br>References Shaohua, Ch., et al.: Bioorg. Med. Chem. Lett., 22, 1208 (2012);<br></p>

<p>Applications 6-​Amino-​5-​nitrochromen-​2-​one is a reagent used in the synthesis of pyranopyridinediones.<br>References Khan, M. et al.: J. Pure App. Sci., 22, 37 (2004);<br></p>

<p>Applications 1,11-Diaminoundecane<br></p>

<p>Applications Methyl 4-amino-2-fluorobenzoate<br></p>

<p>Applications Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid is an intermediate used in the synthesis of ent-Abacavir (A105015), which is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br></p>

<p>Applications Methyl (1R,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Ester is used in the discovery of a potent, selective and orally bioavailable dual CCR2 and CCR5 antagonist.<br>References Zheng, C., et al.: Bioorg. Med. Chem. Lett., 21, 1442-1446 (2011)<br></p>

<p>Applications [2-(aminocarbonyl)phenoxy]acetic acid (cas# 25395-22-6) is a useful research chemical.<br></p>

<p>Applications Trimethyl (2-N-t-Butoxycarbonylamino)ethylammonium Bromide is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Amino-2-(formylamino)-3-iminopropanamide is a Temozolomide (T017775) impurity. Temozolomide acts as a imidazotetrazine alkylating agent. An antineoplastic.<br>References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997), Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999), Hait, W., et al.: Cancer Res., 69, 1263 (2009),<br></p>

<p>Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.<br>References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)<br></p>

<p>Applications 6-Aminohexanenitrile (cas# 2432-74-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,4-Diaminobutane is an amino acid degradation product. Used in the preparation of hexahydropyrimidines as novel hepatitis C virus inhibitors. Also a reagent in the synthesis of antibacterial castor oil-based polyurethane membranes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hwang, J. et al.: Eur. J. Med. Chem., 70, 315 (2013); Yari, A. et al.: J. Biomed. Mat. Res., 102A, 84 (2014);<br></p>

<p>Applications N-(furan-3-ylmethyl)cyclohexanamine (cas# 462068-58-2) is a useful research chemical.<br></p>

<p>Applications 2-(bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid (cas# 171557-31-6) is a useful research chemical.<br></p>

<p>Applications (2S,3R,4E)-3-Benzoyl-2-tert-butyloxycarbonylamino-4-octadecen-1,3-diol (cas# 299172-59-1) is a compound useful in organic synthesis.<br>References Kinjo, Y., et al.: Chem. Biol., 15, 654 (2008),<br></p>