Amides

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<p>N-Chloro-4-toluenesulfonamide sodium (NCTS) is a disinfectant that is used to treat wastewater and as a preservative for water. It has been shown to be effective against bacteria, fungi, and viruses. NCTS is an antimicrobial agent that reacts with the matrix in which it is applied to form chloramines-T (NHClO). The chloramines-T inhibits the activity of enzymes such as those involved in DNA synthesis and protein synthesis. This reaction also generates an electric current due to the redox potentials of the reactants. The presence of aziridines in NCTS leads to crosslinking between proteins, which enhances its effectiveness as a disinfectant.<br>NCTS has been shown to have no adverse effects on human erythrocytes or DNA when used at concentrations up to 100 µg/mL.</p>

<p>Tris[N-ethyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-heptadecafluoro-N-(2-hydroxyethyl)-1-octanesulfonamide] phosphate is a sulfonate that has been mixed with other chemicals. It is used as a chemical substance for the production of other substances. Tris[N-ethyl-1,1,2,2,3]3,[4],4,[5],5,[6],6-[7],7,[8],8-[heptadecafluoro-N-(2-hydroxyethyl)-1-octanesulfonamide] phosphate has not been classified by the International Agency for Research on Cancer (IARC).</p>

<p>Clorsulon is an anthelmintic drug that belongs to the group of benzimidazoles. It is used in veterinary medicine to treat nematode and cestode infections, as well as tapeworm infections. Clorsulon is a dispersive solid-phase extraction (DSPE) extractant that can be used for the separation of drugs and their metabolites from biological fluids. The chemical stability of clorsulon was assessed by exposing it to various solvents and pHs. Clorsulon was found to be stable in acetate, benzene, chloroform, ethyl acetate, ethanol, methanol, and water at pH 1-14 and a variety of temperatures ranging from -20 ˚C to 50 ˚C. No significant loss or degradation occurred after exposure to these conditions for up to 24 hours.</p>

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<p>Picotamide is a drug that belongs to the class of drugs that inhibit platelet aggregation. This drug is used in the treatment of coronary artery disease and other cardiovascular diseases. Picotamide has been shown to have pharmacological effects on the heart, such as lowering blood pressure and reducing heart rate. It also has a covalent linkage with proteins, which may be due to its ability to activate receptors for biological properties like cell proliferation or differentiation. Picotamide has been shown to prevent infectious diseases, such as septicemia, by inhibiting bacterial growth. The chemical stability of picotamide makes it an attractive candidate for use in gene therapy because it can be stored at room temperature without losing its activity.</p>

<p>2-Methoxybenzamide is an amide with a p-hydroxybenzoic acid moiety. It has been shown to be an effective inhibitor of the enzyme histone deacetylase, which is involved in the regulation of gene expression. 2-Methoxybenzamide also has antiinflammatory activity and has minimal toxicity. This drug is used as a research tool for studying the immune system and its effects on hyperproliferative diseases such as cancer and autoimmune diseases. 2-Methoxybenzamide can also be used to treat metabolic disorders and physiological effects. The drug binds to intracellular targets through intermolecular hydrogen bonds that are mainly found in protein structures, including cytochrome P450s, protein kinases, DNA polymerases, transcription factors, and proteases.</p>

<p>This compound is a benzamide derivative that is oxidized by nature. It has been shown to undergo ring-opening in the presence of reducing agents, such as sodium borohydride, and yields 2-amino-4-chlorobenzaldehyde. This reaction system uses an efficient catalyst such as manganese dioxide to help speed up the rate of this reaction. The product of this reaction is then converted into a variety of isatins depending on the conditions used.</p>

<p>Trifluoromethanesulfonamide is a strong acid that has been shown to inhibit the proteolytic activity of human secretase. It binds to a specific site on the enzyme and prevents it from cleaving the substrate. This inhibition slows down the progression of Alzheimer's disease, Parkinson's disease, and other related disorders. Trifluoromethanesulfonamide has also been shown to bind to metal hydroxides, such as iron hydroxide, which may be due to its ability to form hydrogen bonds with these metals. Structural analysis reveals that trifluoromethanesulfonamide contains a pyrazole ring and two chlorine atoms, one in the para position and one in the meta position.</p>

<p>N-(n-Butyl)phosphoric triamide is an analog of phosphoric acid that has a matrix effect on the uptake of water molecules by cells. N-(n-Butyl)phosphoric triamide is used as a sample preparation agent in microbiological analysis and as an antimicrobial agent to inhibit the growth of bacteria. This compound inhibits the growth rate of triticum aestivum, which may be due to its ability to inhibit nitrous oxide, a key intermediate in bacterial metabolism. N-(n-Butyl)phosphoric triamide has been shown to have an inhibitory effect on water molecule formation and growth rate in bacteria.</p>

<p>Methylthioacetic acid is a weak organic acid that is used as an ophthalmic drug. When methylthioacetic acid is activated, intramolecular hydrogen bonds form between the methylthiosulfonate ion and the nitrate ion. This process requires spin resonance to take place, which can be explained by the functional theory of kinetics. The reaction of methylthioacetic acid with nitrate ions to form methylthiosulfonate ions has been shown to be rapid and reversible in both dry weight and wet weight experiments. The alkylation of methylthioacetic acid with ethyl bromoacetate has been shown to produce thermochemically stable imine and phosphate ions.</p>

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<p>1-Naphthaleneacetamide is a plant growth regulator that belongs to the class of compounds known as auxins. It inhibits the production of chlorophyll and reduces photosynthetic activity in plants, thereby causing a decrease in chlorophyll content. 1-Naphthaleneacetamide has been shown to have genotoxic effects on human cells in tissue culture. This agent also has an effect on DNA damage and repair and can be used as an analytical method for determining the presence of surfactant sodium dodecyl (SDS) in urine samples by fluorescence spectrometry.</p>

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<p>2-Amino-5-methylbenzamide (2AMB) is a potent inhibitor of the enzyme dihydropyrimidine dehydrogenase and is used in cancer research for its ability to inhibit tumor cell line growth. 2AMB has been shown to inhibit the synthesis of DNA, RNA, and protein in various human cell lines. The mechanism of this inhibition is not well understood, but it may be due to its ability to inhibit the activity of synthetases involved in nucleotide biosynthesis or by inhibiting the reaction system that converts hydration into ATP.</p>

<p>Furiosus is a monomeric and homodimeric protein that belongs to the group of S-adenosylmethionine synthetases. Furiosus is an enzyme that catalyzes the formation of S-adenosylmethionine from methylamine and ATP. Furiosus interacts with polymerase, subtilis, and catalysis to form a holoenzyme complex. Furiosus has been shown to have cleavage activity against peroxide and hydrogen peroxide, which is due to its ability to generate reactive oxygen species. Furiosus has also been shown to be a molecular modeling target for the development of new antibiotics.</p>

<p>2,3-Dichlorobenzamide is a herbicide with a stable structure. It has been shown to be effective against the weed species Agropyron repens and other grasses that grow in wetland conditions. 2,3-Dichlorobenzamide inhibits the growth of these plants by causing chlorosis, which is characterized by yellowing of leaves. 2,3-Dichlorobenzamide is toxic to aquatic organisms and can cause pollution in water systems. The molecular electrostatic potential of 2,3-Dichlorobenzamide has been studied using computer models and the parameters have been used to predict its toxicity to various tissues such as nerves or liver cells.</p>

<p>N-Propyl-N-(2,3-dihydroxypropyl)perfluoro-n-octylsulfonamide is a fine chemical that can be used as a reagent and speciality chemical. It is a versatile building block that can react with other compounds to produce new products. The compound is a complex compound that has been shown to have high quality in the laboratory.</p>

<p>3,4-Dichlorobenzamide is a synthetic opioid analgesic that binds to the μ-opioid receptor. It has a side-effect profile that is similar to other opioids, with an addiction risk and potential for abuse. 3,4-Dichlorobenzamide has been used in the synthesis of new drugs, such as phenazepam (a benzodiazepine) and etizolam (a thienodiazepine). This drug is chiral and can be synthesized in two stereoisomeric forms: 3-(+)-chloro-N-(2-chlorophenyl)benzamide and 3-(−)-chloro-N-(2-chlorophenyl)benzamide. The former form is marketed under the trade name Analgin, while the latter form is marketed under the trade name Etilex. The (+) form of this drug has a higher affinity for μ receptors than the (−) form.</p>

<p>Inhibits carbonic anhydrase; diuretic</p>

<p>L-Alaninamide is a protonated amino acid that reacts with the bacterial cell membrane and causes it to rupture. L-Alaninamide is synthesized by hydrolysis of the ester bond between butyric acid and serine protease in the presence of immobilized d-alanine. The reaction is carried out at a pH of 5.5, and the release of pressor is observed. This reaction takes place in an aqueous solution containing fatty acids as solvents. The type strain of this amino acid is E. coli.</p>

<p>N,N'-Dimethyl-3,3'-dithiodipropionamide (DTDPA) is a strong oxidizing agent that is used as a catalyst in organic synthesis. It can be used to convert xylene and benzene into products that are less toxic and more easily removed from the environment. DTDPA can also be used to remove 2-methyl-4-isothiazolin-3-one, chloroform, and other pollutants from water. DTDPA has been shown to react with hydrogen peroxide or hydrochloric acid to produce oxygen gas and chlorine, which is an effective disinfectant against bacteria such as Staphylococcus aureus or Pseudomonas aeruginosa. This chemical also reacts with toluene or chloroform to produce peroxides which have been shown to have an anti-inflammatory effect on cells.</p>

<p>2-Hydroxy-N-(1-phenylpropan-2-yl)acetamide is a versatile building block that can be used as a reagent or research chemical. This compound is an intermediate in the synthesis of many other organic compounds and has been shown to be useful for the production of pharmaceuticals, agrochemicals, and other industrial chemicals. The CAS number for this compound is 99985-83-8.</p>

<p>2-Cyanoacetamide is an organic compound that is used in pharmaceutical preparations. It reacts with malonic acid to form a dioxime, which is a precursor of various drugs. The optimum concentration for the reaction to occur is at 10% (w/v). The reaction mechanism has not been fully elucidated and it involves the transfer of nitrogen from an amide group to a carbonyl group. 2-Cyanoacetamide has shown anti-angiogenic effects in mice by inhibiting the expression of Mcl-1 protein, which is involved in the regulation of apoptosis and inflammation. This drug also has biological functions as a precursor for dopamine, which helps regulate motor and cognitive functions.</p>

<p>2,5-Dimethoxybenzamide is a potent inhibitor of the enzyme DECATENASE. This enzyme plays an important role in the biosynthesis of the aromatic amino acids phenylalanine and tyrosine. 2,5-Dimethoxybenzamide has been shown to have anticancer activity in vitro and in vivo. Remoxipride is a synthetic drug that competitively inhibits the action of benzodiazepines on GABA receptors by binding to them with high affinity. It was developed as an antipsychotic agent but was never marketed for this indication due to its adverse effects on motor coordination. Remoxipride has also been shown to have estrogenic activity, which may be due to its ability to bind with high affinity and inhibit the enzyme aromatase, which converts testosterone into estradiol.</p>

<p>4-Cyanobenzamide is a naphthalene derivative that is both reactive and intramolecular. It has been shown to react with the amino group of peptides, forming a ruthenium complex. The functional groups are acceptors and donors that can be used in assays for the detection of anions or cations. 4-Cyanobenzamide reacts with water to release hydrogen gas, which can be used to measure its hydration ability. This compound has been synthesized using solid-phase synthesis and it has amide bonds that vibrate at a specific frequency.</p>

<p>5-Amino-1,3,4-thiadiazole-2-sulfonamide is a chemical compound that inhibits the growth of skin cancer cells. It has inhibitory properties against choroidal neovascularization induced by dorzolamide hydrochloride and other pharmacological agents. 5-Amino-1,3,4-thiadiazole-2-sulfonamide has also been shown to have antiangiogenic activity in vitro and in vivo assays. 5ATTS inhibits the growth of bacteria and fungi by inhibiting fatty acid synthesis. The drug also has been shown to be effective in treating diabetic neuropathy and fluorescein angiography associated with itchy eyes.</p>

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<p>3-Bromobenzamide is an amide compound, which is a functional group. It has a molecular weight of 273.3 g/mol and three amine groups. The 3-methoxybenzamide moiety in the molecule can be protonated, which provides the hydration of the molecule and increases its solubility in water. This molecule also has a dipole moment due to the presence of two amide groups.<br>The synthesis of 3-bromobenzamide starts with the reaction between 3-aminobenzoic acid and benzoyl chloride to form 3-benzoyloxybenzoic acid. This is then reacted with ammonia to form 3-aminobenzamide. Finally this is converted into 3-bromobenzamide by reacting it with bromine in the presence of potassium carbonate as a catalyst. <br>This molecule is used as an inhibitory compound for mammalian cell proliferation, specifically for cancer cells</p>

<p>Coconut diethanolamide is a chemical substance that is used as a test compound in carcinogenesis studies. It is a fatty acid and a fatty alcohol, and it has been shown to promote the growth of cancer cells. Coconut diethanolamide has not been found to be an allergen, but it has shown carcinogenic potential. The bioassay for long-term exposure to coconut diethanolamide showed epidermal hyperplasia in mice.</p>

<p>2,3-Diaminobenzamide is a synthetic aromatic compound that is used as a radiation stabilizer. It is also an effective antimicrobial agent with reactive properties against bacteria and fungi. 2,3-Diaminobenzamide has been shown to have anti-cancer properties and can be used to treat inflammatory diseases such as rheumatoid arthritis or ulcerative colitis. The intramolecular hydrogen bond between the amide group and the benzene ring in 2,3-diaminobenzamide contributes to its stability and biological activity.</p>

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<p>Homoveratramide is a synthetic drug that is used as an antibacterial agent. It has a broad spectrum of activity against bacteria, fungi, and protozoa. Homoveratramide has been shown to be effective against both Gram-positive and Gram-negative bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Salmonella enterica, Pseudomonas aeruginosa, and Klebsiella pneumoniae. Homoveratramide inhibits the synthesis of DNA by binding to the enzyme ribonucleotide reductase. This produces a bacteriostatic effect on the cell by halting DNA replication and transcription.</p>

<p>μ-opioid receptor agonist; calcium channel inhibitor; anti-diarrheal</p>

<p>Sodium diformylamide is a chemical compound that belongs to the class of amides. It has been shown to inhibit the activity of a number of enzymes including alkanoic acid, inorganic acid, and amide. It has also shown promising results in the prevention and treatment of metabolic disorders such as hepatitis. The asymmetric synthesis of this compound is achieved through the use of trifluoroacetic acid and nitrogen atoms. The biological properties of sodium diformylamide have not yet been fully researched but it has been found to have integrin receptor-binding properties.</p>

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<p>N-((1-(2-(tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide is a novel antiarrhythmic drug that inhibits the activation of cardiac cells. It was shown to inhibit proliferation and migration of human leukemia cells in vitro and to inhibit tumor growth in vivo. N-(1-(2-(tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide has been shown to have cardioprotective effects in Sprague Dawley rats, reducing the incidence of ventricular tachycardia and fibrillation. The clinical studies conducted so far have not revealed any adverse effects on the heart or other organs.</p>

<p>N-[2-(2,3-Dimethoxyphenyl)ethyl]-2-chlorobenzamide is a versatile building block that can be used as a reaction component and reagent. It is an intermediate in the synthesis of pharmaceuticals and fine chemicals and has been shown to be useful in the synthesis of complex compounds. This compound reacts with nucleophiles, such as amines and alcohols, by replacing the chloride group with a variety of functional groups. The product is then hydrolyzed to release the original reactant. N-[2-(2,3-Dimethoxyphenyl)ethyl]-2-chlorobenzamide has a CAS number of 320576-19-0 and can be found at ChemDiv.com.</p>

<p>2-((4-Methylphenyl)sulfonyl)ethanamide is an amide that has been shown to have antibacterial activity. It binds to the DNA of bacteria, inhibiting its replication and transcription. This drug also inhibits the growth of influenza virus in cell culture. 2-((4-Methylphenyl)sulfonyl)ethanamide is a sensor for chloride ions, which may be used as treatments for bacterial infections. This drug is also able to inhibit the replication of bacteria that are resistant to other antibiotics, such as penicillin. The unsaturated alkyl group on this molecule allows it to be activated by radiation treatment, which may be useful in the treatment of cancer cells or viral infections.</p>

<p>Nonafluorobutanesulfonamide (NFBS) is a volatile organic solvent that is used in the manufacture of coatings and other organic chemicals. It has been shown to have a high vapor pressure, which makes it useful for drying solvents. NFBS is also used as an intermediate in the production of fluorinated acrylates and methacrylates. NFBS reacts with styrene monomers to form ionic forms, and can be converted to its neutral form by reaction with acrylonitrile or acrylates. Nonafluorobutanesulfonamide has been shown to cause liver cancer in rats, but this effect has not been observed in humans.</p>

<p>2,5-Dichlorobenzamide is a halogenated compound that inhibits topoisomerase and proteasome activity. It has been shown to be cytotoxic against cancer cells in vitro. 2,5-Dichlorobenzamide can also inhibit the growth of tuberculosis bacteria and may be used as an operational agent for weed control. The safety profile of this drug has not yet been fully determined. 2,5-Dichlorobenzamide is available in two crystalline forms, both of which are active with different degrees of potency.<br>2,5-Dichlorobenzamide is a hybridization inhibitor that inhibits the enzyme DNA gyrase and proteasome activity. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division.</p>

<p>Alkylating agent; anti-cancer agent</p>

<p>4-Aminothiobenzamide (4ATB) is a chemical compound that is used as an anticancer agent and an antimicrobial agent. It has been shown to have antitumor activity against human liver cancer cells and anticancer activity against human adrenergic receptor-positive lung cancer cells. 4ATB binds to the chloride ion present in the cell membrane, which prevents the influx of chloride ions into the cell. This leads to an increase in intracellular pH and disruption of cellular functions. 4ATB has also been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) infections by inhibiting bacterial growth and reducing the production of proteins vital for cell division.</p>

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<p>2-Chloro-4-nitrobenzamide is a drug that belongs to the sulfa drugs. It has been shown to be effective in treating autoimmune diseases, particularly bowel disease and inflammatory bowel disease. 2-Chloro-4-nitrobenzamide inhibits the synthesis of fatty acids by blocking the enzyme acetyl CoA carboxylase, which is involved in the formation of long chain fatty acids. This drug also has immunosuppressive activities, which may be due to its ability to block T cell proliferation. 2-Chloro-4-nitrobenzamide is used as a chemical intermediate for antibiotics such as maduramicin ammonium and salinomycin sodium. It is also used as a dietary supplement or pharmaceutical dosage form for cardiac glycoside drugs such as digoxin.</p>

<p>a-[2-(Diisopropylamino)ethyl]-a-phenyl-2-pyridineacetamide is a hydrogen bond donor. It has been shown to have cytotoxicity in vitro, with parameters that can be used for accurate prediction of descriptors. These descriptors are informative and insightful, which can be used for regression analyses and linear regression methods. The pharmacokinetic properties of a-[2-(Diisopropylamino)ethyl]-a-phenyl-2-pyridineacetamide have been studied in humans and have shown linearity between dose and plasma concentration.</p>

<p>N-[(8-Fluoro-2,3-Dihydro-1-Methyl-5-Phenyl-1H-1,4-Benzodiazepin-2-Yl)Methyl]-3-Furancarboxamide is a hydrophobic, implanting drug with an iontophoresis device. It has been shown to have therapeutic effects in cancer. The drug is a targetable molecule that can be used for diagnostic purposes and the treatment of various cancers. N-[(8-Fluoro-2,3-Dihydro-1,5 -Phenyl 1H -1,4 Benzodiazepin 2 Yl) Methyl] 3 Furancarboxamide has been shown to inhibit cell proliferation by blocking the synthesis of proteins required for DNA replication and also inhibits the activity of protein kinase C.</p>

<p>6-Methylnicotinamide is a transport inhibitor that prevents the uptake of fatty acids and growth factors into cells. It has been shown to inhibit the activity of glutamate receptors by blocking the interaction between these receptors and their binding partners, which are called co-agonists. 6-Methylnicotinamide has also been shown to inhibit the synthesis of virus proteins in vitro and in vivo. There is a lack of evidence on its safety profile. 6-Methylnicotinamide may be used to treat hepatitis C and colorectal carcinoma.</p>

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