Amides

<p>2-[(2,6-Dichlorophenyl)amino]-N,N-dimethylbenzeneacetamide is a reagent, complex compound and useful intermediate with a CAS number of 21789-06-0. It is a fine chemical that can be used as a building block in the synthesis of other compounds. It has been shown to be useful in the production of speciality chemicals and research chemicals. The versatility of this compound makes it an excellent scaffold for the synthesis of other compounds. This product is not intended for human or animal use.</p>

<p>1-Adamantylcyanamide is a trimethyl triazine that has been shown to be a blocker of glutamate receptors. It has been studied in animal models of schizophrenia and depression, where it showed potential as an antipsychotic and antidepressant. 1-Adamantylcyanamide blocks the NMDA receptor in the brain by binding to the glycine site. This prevents the passage of chloride ion into the cell and causes hyperpolarization of the membrane, which may lead to inhibition of neuronal activity. It also inhibits the acid catalyst introduced into tuberculosis cells, which can prevent their growth. 1-Adamantylcyanamide can also be used to form trimers with other molecules, such as cyanuric acid or 3-indoxyl-beta-D-galactopyranoside, respectively.</p>

<p>1-Benzyl-1,4-dihydronicotinamide is a drug that has been shown to have potential in treating metabolic disorders by restoring the balance of nitrogen atoms. It has been shown to be effective in inhibiting the production of nitric oxide and other reactive oxygen species (ROS) which are involved in the pathogenesis of inflammation, septic shock and HIV infection. 1-Benzyl-1,4-dihydronicotinamide also inhibits light emission from cells. This effect is due to its ability to reduce the concentration of NADH and ATP, which are necessary for the light emitting reaction. The drug's mechanism of action is not well understood but it may be related to its ability to block dimethyl fumarate (DMF), an inhibitor of monoclonal antibody production. The physiological function of this drug is not yet well understood but it may be related to its ability to inhibit the proliferation of human immunodeficiency virus (HIV).</p>

<p>2-Hydroxy-N-(1-phenylpropan-2-yl)acetamide is a versatile building block that can be used as a reagent or research chemical. This compound is an intermediate in the synthesis of many other organic compounds and has been shown to be useful for the production of pharmaceuticals, agrochemicals, and other industrial chemicals. The CAS number for this compound is 99985-83-8.</p>

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<p>2-Chloro-5-nitrobenzene sulfonamide (2CNS) is a glycol ether that has been shown to inhibit the activity of carbonic anhydrase. It has been shown to be a competitive inhibitor of the enzyme, and can be used as a lead compound for developing new drugs. 2CNS has been shown to inhibit an anhydrase that is found in bacteria, such as Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus. This inhibition causes increased levels of hydrogen ions in the bacterial environment, which leads to the acidification of their surroundings. 2CNS also inhibits chloride ion uptake in these bacteria.<br>2CNS's pharmacophore includes two aromatic hydrocarbon rings with at least one hydrogen bond acceptor group on each ring. This pharmacophore is responsible for its inhibition of carbonic anhydrase and chloride ion binding site.</p>

<p>L-Alaninamide is a protonated amino acid that reacts with the bacterial cell membrane and causes it to rupture. L-Alaninamide is synthesized by hydrolysis of the ester bond between butyric acid and serine protease in the presence of immobilized d-alanine. The reaction is carried out at a pH of 5.5, and the release of pressor is observed. This reaction takes place in an aqueous solution containing fatty acids as solvents. The type strain of this amino acid is E. coli.</p>

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<p>Thioacetamide is a chemical compound that has been used as a model system to study apoptosis. It is also known to cause injury and biochemical changes in cells. Thioacetamide is metabolized by cytochrome P450 enzymes and conjugated with glucuronic acid, which prevents it from binding to DNA or protein. The oxidation of thioacetamide by cytochrome P450 enzymes leads to the formation of reactive oxygen species that may cause DNA damage. Apoptosis induced by thioacetamide has been shown to be mediated through the mitochondrial pathway, which involves the release of cytochrome C, activation of caspase-9, and cleavage of poly (ADP-ribose) polymerase (PARP). Thioacetamide also inhibits sorbitol dehydrogenase activity, which leads to an accumulation of sorbitol in cells. This accumulation can activate transcriptional factors such as nuclear factor kappa B (NF-κB), leading to</p>

<p>Sulphanilamide is an antimicrobial agent that inhibits the growth of bacteria by binding to their enzymes and blocking protein synthesis. In addition, sulphanilamide has been shown to inhibit the production of sulfanilamide, a potent inhibitor of tetracycline. Sulphanilamide is soluble in water and alcohol but not in organic solvents. The solubility of sulphanilamide can be increased by adding sodium salts or pH adjustment. Sulphanilamide is also used for wastewater treatment as it has inhibitory properties against sulfate-reducing bacteria. X-ray crystal structures have revealed that sulphanilamide binds to the active site of bacterial beta-lactamases through hydrogen bonds with both the NH group and the COOH group on its sulfur atom, resulting in inhibition of these enzymes. Sulphanilamide also interferes with bacterial DNA replication by inhibiting dna gyrase and topoisomerase IV. Sulphanilamide also</p>

<p>Methylthioacetic acid is a weak organic acid that is used as an ophthalmic drug. When methylthioacetic acid is activated, intramolecular hydrogen bonds form between the methylthiosulfonate ion and the nitrate ion. This process requires spin resonance to take place, which can be explained by the functional theory of kinetics. The reaction of methylthioacetic acid with nitrate ions to form methylthiosulfonate ions has been shown to be rapid and reversible in both dry weight and wet weight experiments. The alkylation of methylthioacetic acid with ethyl bromoacetate has been shown to produce thermochemically stable imine and phosphate ions.</p>

<p>Picotamide is a drug that belongs to the class of drugs that inhibit platelet aggregation. This drug is used in the treatment of coronary artery disease and other cardiovascular diseases. Picotamide has been shown to have pharmacological effects on the heart, such as lowering blood pressure and reducing heart rate. It also has a covalent linkage with proteins, which may be due to its ability to activate receptors for biological properties like cell proliferation or differentiation. Picotamide has been shown to prevent infectious diseases, such as septicemia, by inhibiting bacterial growth. The chemical stability of picotamide makes it an attractive candidate for use in gene therapy because it can be stored at room temperature without losing its activity.</p>

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<p>N-Allyl-N-(4-cyano-2-chlorophenyl)acetamide is a high quality reagent that has been used as an intermediate in the synthesis of fine chemicals, useful scaffolds and building blocks. It is also a versatile building block that can be used to synthesize high quality compounds with a wide range of functionalities. N-Allyl-N-(4-cyano-2-chlorophenyl)acetamide is a speciality chemical that can be used for research purposes. This compound has been shown to produce reactions with other compounds, such as nitrobenzene, to generate useful products.</p>

<p>This compound is a recyclable, multicomponent, element analysis, element, diversity and catalyzed reaction that yields high purity products with high yields. The catalyst is reusable and the NMR data are reproducible.</p>

<p>Oxyclozanide is an antimicrobial agent that inhibits the enzyme activity of chitin synthase in the nematode, which is necessary for the production of chitin. This inhibition leads to disruption of the nematode's cell membrane and death. Oxyclozanide has been shown to be effective against resistant mutants, as well as synergistic with other antimicrobial agents. It is also a specific antidote for oxyclozanide poisoning.</p>

<p>5-Iodosalicylamide is a chemical building block. 5-Iodosalicylamide can be reacted with appropriately functionalised aromatic compounds to afford the corresponding anilides, which have been shown to exhibit anti-fungal and bactericidal properties.</p>

<p>Hydroxy tolbutamide is a drug with an unknown mechanism of action. It has been shown to inhibit the transcription-polymerase chain reaction and human serum in vitro. This drug may be used as a marker for renal disease, as it has been shown to increase the level of magnesium in urine and reduce the rate of protein synthesis in rat liver microsomes. Hydroxy tolbutamide also inhibits receptor activity, which may be due to its ability to inhibit the metabolic rate.</p>

<p>Inducer of apoptosis; NF-κB activator; PP2A modulator</p>

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<p>2,3-Diaminobenzamide is a synthetic aromatic compound that is used as a radiation stabilizer. It is also an effective antimicrobial agent with reactive properties against bacteria and fungi. 2,3-Diaminobenzamide has been shown to have anti-cancer properties and can be used to treat inflammatory diseases such as rheumatoid arthritis or ulcerative colitis. The intramolecular hydrogen bond between the amide group and the benzene ring in 2,3-diaminobenzamide contributes to its stability and biological activity.</p>

<p>4-Fluorophenylacetic acid is a synthetic organic compound that has been used as a model system for the study of the reaction between hydrogen sulfate and hydrogen. 4-Fluorophenylacetic acid is a fluorinated analog of acetamide, which can be synthesized from sodium borohydride and hydrogen fluoride. It has been shown to inhibit the growth of Mycobacterium tuberculosis in an on-line assay and is also active against Mycobacterium avium complex. 4-Fluorophenylacetic acid also inhibits rat liver microsomes with a second order rate constant of 0.0006 M−1 s−1 at pH 7.4 and 37 °C (pH and temperature not specified). The biological properties of 4-fluorophenylacetic acid are not well understood, but it may bind to hydrophobic regions on proteins or DNA through hydrogen bonding interactions.</p>

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<p>Dimethylphosphonoacetamide (DMPPA) is a phosphorus-containing compound that is used as an intermediate in the synthesis of fatty acids. DMPPA can be synthesized by the reaction of ethylene diamine and phosphorus pentoxide, which is a common reagent for preparing phosphorus compounds. The reaction mechanism has been studied using electrochemical impedance spectroscopy. This study revealed that DMPPA can be converted to a water-soluble product by treatment with water vapor or by adding cotton. In addition, the kinetic data obtained from this study showed that the reaction rate was affected by temperature and the type of solvent used. The frequency shift observed during this study indicated that nitrogen atoms are involved in the reaction mechanism.</p>

<p>Ethionamide is a drug that is used for the treatment of tuberculosis. It binds to the enzyme preparations in the bacterial cell wall by competitive inhibition, which prevents formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. The sulfoxide form of ethionamide is converted to the sulfone form when it enters the body. This conversion takes place primarily in the liver with assistance from alcohol dehydrogenase, cytochrome P450, and glutathione reductase. The sulfone form has higher potency than its precursor (sulfoxide) because it has lower protein binding affinity and more rapid elimination from plasma.</p>

<p>4-Hydroperoxycyclophosphamide (4-HPPC) is a cytotoxic agent with anti-cancer properties. It is a prodrug that is converted to 4-hydroxycyclophosphamide, the active form of the drug, by hydrolases in cells. The cytotoxicity of 4-HPPC has been demonstrated using a model system of human erythrocytes and HL60 cells. This drug also has an effect on tumor growth and metastasis, as well as on bowel disease. Rats treated with 4-HPPC showed decreased levels of blood glucose, increased glutathione peroxidase activity, and a decrease in the number of colonic tumors after only one dose. The low-dose group had improved mitochondrial membrane potential and an increase in cell factor receptor activity. These results indicate that 4-HPPC may be a useful anti-cancer compound for treating various types of cancer including colon cancer.</p>

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<p>1-(Aminomethyl)cyclopropanecarboxamide hydrochloride is a versatile building block that can be used in the synthesis of complex compounds. It has been shown to be an excellent reagent for the synthesis of novel pharmaceuticals and speciality chemicals. This compound is also a useful intermediate for the preparation of high-quality products and can be used as a reaction component or scaffold in synthesis.</p>

<p>Anthranilamide is used for non-selective, efficient fluorescent labelling of glycans.</p>

<p>2-Iodoacetamide is a synthetic retinoid that binds to the DNA of cells, altering transcription. It also has been found to be effective in treating bowel disease and has been shown to have dna binding activity. The compound was synthesized by attaching iodine molecules to acetamide. 2-Iodoacetamide targets the protein thiols on the surface of cells, which are responsible for oxidation and damage due to reactive oxygen species (ROS). This compound is metabolized by alcohol dehydrogenase and can be used as a biological sample or natural compound.</p>

<p>Homoveratramide is a synthetic drug that is used as an antibacterial agent. It has a broad spectrum of activity against bacteria, fungi, and protozoa. Homoveratramide has been shown to be effective against both Gram-positive and Gram-negative bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Salmonella enterica, Pseudomonas aeruginosa, and Klebsiella pneumoniae. Homoveratramide inhibits the synthesis of DNA by binding to the enzyme ribonucleotide reductase. This produces a bacteriostatic effect on the cell by halting DNA replication and transcription.</p>

<p>μ-opioid receptor agonist; calcium channel inhibitor; anti-diarrheal</p>

<p>Nonafluorobutanesulfonamide (NFBS) is a volatile organic solvent that is used in the manufacture of coatings and other organic chemicals. It has been shown to have a high vapor pressure, which makes it useful for drying solvents. NFBS is also used as an intermediate in the production of fluorinated acrylates and methacrylates. NFBS reacts with styrene monomers to form ionic forms, and can be converted to its neutral form by reaction with acrylonitrile or acrylates. Nonafluorobutanesulfonamide has been shown to cause liver cancer in rats, but this effect has not been observed in humans.</p>

<p>2-Chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamide (CPA) is a chemical compound that belongs to the class of phenyl pyrazoles. It has a thermal stability and is soluble in organic solvents. CPA crystallizes in the monoclinic system with the space group P21/c, with the following unit cell parameters: a = 8.943(4) Å, b = 7.878(3) Å, c = 17.834(6) Å, α = 90°, β = 112° and γ = 90°. In this crystal structure, there are two molecules of chloride per molecule of CPA. The crystal x ray diffraction pattern showed that this compound forms dimers in solution at room temperature and can be dissolved</p>

<p>2-Phenylbenzamide (2PB) is a drug that belongs to the class of anthelmintics. It binds to the nicotinic acetylcholine receptor and inhibits the release of acetylcholine at neuromuscular junctions, leading to paralysis and death of the parasite. 2PB also has been shown to have anti-inflammatory properties in mice with colitis, which may be due to its ability to inhibit prostaglandin synthesis. The molecular docking analysis showed that 2PB binds covalently with nitro-containing molecules, such as nitrosamines, which are found in cigarette smoke and are known carcinogens. This binding may contribute to the development of cancer through inhibition of DNA repair mechanisms.</p>

<p>Morpholine-4-carboxamide is a polymerase chain inhibitor that inhibits the activity of DNA polymerases. It binds to the DNA template strand and prevents the enzyme from adding nucleotides to the primer strand, thereby inhibiting DNA synthesis. Morpholine-4-carboxamide has shown efficacy in treating hyperproliferative diseases such as cancer cells and psoriasis. This drug has been shown to inhibit caspase activation and histone protein acetylation, which may be related to its anti-cancer properties. Morpholine-4-carboxamide also binds to cannabinoid receptor 2 (CB2) and may have therapeutic effects on inflammatory diseases such as psoriasis and arthritis.</p>

<p>Dopamine (D2) receptor antagonist; 5-HT4 serotonin receptor agonist</p>

<p>3,5-Dinitrobenzamide is a sulfa drug that inhibits the growth of bacteria by inhibiting 3-dehydroquinate synthase (EC 4.2.1.23) and 3-dehydroquinate dehydratase (EC 4.2.1.46). The enzyme catalyzes the conversion of 3-dehydroquinic acid to quinic acid, which is an intermediate in the biosynthesis of benzoic acid from glucose. This inhibition occurs because 3,5-dinitrobenzamide forms a glycosidic bond with Cys34 in these enzymes, which prevents their function. This drug has been shown to have significant cytotoxicity against human pathogens and model organisms such as Salmonella typhimurium and Escherichia coli, but not against Saccharomyces cerevisiae or Candida albicans.</p>

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<p>N-(5-Bromoacetamidylpentyl) acrylamide is employed in the synthesis of substrates used for nucleotide sequence determination, covalently linked to polymer coatings such as poly(N-(5-azidoacetamidylpentyl)acrylamide-co-acrylamide) (PAZAM). Polynucleotide-binding substrates find application as molecular arrays and flow cells.</p>

<p>C2 dihydroceramide is a lipid that belongs to the group of sphingolipids and is involved in neuronal death. It is a precursor for ceramide, which can also induce apoptosis. C2 dihydroceramide has been shown to inhibit axonal growth by interfering with the polymerase chain reaction, as well as inducing autophagy through toll-like receptor 4 signaling. This lipid has also been shown to inhibit intracellular Ca2+ levels, mitochondrial functions, and bowel disease. C2 dihydroceramide was identified in HL-60 cells and may be used as an analytical method for detecting other sphingolipids.</p>

<p>Clorsulon is an anthelmintic drug that belongs to the group of benzimidazoles. It is used in veterinary medicine to treat nematode and cestode infections, as well as tapeworm infections. Clorsulon is a dispersive solid-phase extraction (DSPE) extractant that can be used for the separation of drugs and their metabolites from biological fluids. The chemical stability of clorsulon was assessed by exposing it to various solvents and pHs. Clorsulon was found to be stable in acetate, benzene, chloroform, ethyl acetate, ethanol, methanol, and water at pH 1-14 and a variety of temperatures ranging from -20 ˚C to 50 ˚C. No significant loss or degradation occurred after exposure to these conditions for up to 24 hours.</p>

<p>Heptadecafluoro-N,N-Bis(2-Hydroxyethyl)Octanesulphonamide is a lubricant that is used in the manufacture of polyester films. It is insoluble and has excellent compressive properties. This compound is soluble in both organic solvents and water, and can be applied as a transfer agent or to obviate the need for a separate lubricant. Heptadecafluoro-N,N-Bis(2-Hydroxyethyl)Octanesulphonamide is an inorganic material that does not react with other materials. It also has good deformation resistance and low hardness. The particle size of this compound is between 5 and 10 microns.</p>

<p>2-Veratramide is a drug that belongs to the group of amides. It is a highly soluble, water-soluble and lipophilic molecule. The molecular modeling study revealed that it has a hydroxyl group in its structure and a hydrogen bond with the intramolecular hydrogen atom. 2-Veratramide has been observed to inhibit protein synthesis and cellular proliferation by binding to cancer cells or inflammatory cells. It also binds to dopamine receptors, inhibiting uptake of dopamine and subsequent activation of downstream signaling pathways. 2-Veratramide is an inhibitor of nitric oxide synthase (NOS), which plays an important role in inflammation, vascular tone, neurotransmission, and cell proliferation.<br>2-Veratramide inhibits NOS by competitively binding to the heme moiety at the active site of the enzyme, thereby blocking access to substrate arginine.</p>

<p>3,5-Dihydroxybenzamide is an amide derivative that has anticancer activity. This compound inhibits the growth of C. glabrata by inhibiting protein synthesis in the mitochondria and DNA replication in the nucleus. 3,5-Dihydroxybenzamide also inhibits the growth of cancer cells by binding to a molecule that is involved in cancer cell proliferation. The inhibitor molecule binds to a specific site on the molecule, preventing it from forming new cancer cells. The mechanism of action for this compound is not known, but may be due to its ability to bind with chloride ions or its ability to form supramolecular chemistry with other molecules.</p>

<p>2,2,2-Trifluoro-N-(4-piperidinyl)acetamide (TFAPA) is a nucleic acid analog that binds to the target nucleic acid. TFAPA is a morpholino compound with an amide linkage between the morpholine ring and the acetic acid group. TFAPA is a sequence-specific DNA analog that inhibits protein synthesis by binding to the target nucleic acid. TFAPA can also be used as a probe for the detection of abnormal sequences in RNA.</p>

<p>4-Hydroxy-3,5-dimethoxybenzamide is a phenolic compound that is soluble in organic solvents. It has been shown to bind to fatty acid sequences and neutral polypeptides in the presence of an acidic or basic environment. 4-Hydroxy-3,5-dimethoxybenzamide has also been shown to have catalytic activity, which may be due to its ability to form a polymeric matrix with other compounds.</p>

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