Amides

<p>Veratramide is a levorotatory, vanillic acid that has been synthesized by hydrolysis of esomeprazole. It is an ester of vanillic acid and hydrochloric acid. The cis-isomer is the more active form. Veratramide has been shown to be a prodrug for cisplatin, which is used in the treatment of cancer. Veratramide can also be metabolized to acetyl derivatives or flavonoids such as vitexin and metformin hydrochloride, which have anti-diabetic effects. Veratramide also binds to chloride ion channels, hypervalent ions (e.g., AlCl3), and quaternary ammonium salts (e.g., tetraethylammonium chloride).</p>

<p>Tiaramide hydrochloride is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandins. It has been shown to have an anti-inflammatory activity in bowel disease and inflammatory bowel disease, which may be due to its ability to inhibit the production of prostaglandin synthesis. Tiaramide hydrochloride is also a coumarin derivative that can form an n-oxide on exposure to air or light. It has been used in tissue culture experiments as a nanoparticulate composition, where it was found to have a dose-dependent effect on cell viability and proliferation. Tiaramide hydrochloride has been used in sample preparation for human serum and rat liver microsomes, where it showed a hydroxyl group that binds with fatty acids.</p>

<p>N,N'-Dimethyl benzamide (DMAB) is an aryl halide that reacts with hydrogen to form the corresponding carbonyl group. The reaction solution of DMAB and hydrogen gas produces a chemical structure that resembles a hydrogen bond. DMAB has been shown to have anti-inflammatory effects in animals with inflammatory diseases. It has also been studied for its ability to inhibit the formation of amyloid plaque, which is associated with Alzheimer's disease. In addition, DMAB has been shown to have therapeutic effects against boron nitride and amides.<br>The crystal structure of DMAB can be found in both crystalline polymorphs: monoclinic and triclinic. The triclinic form is stable at room temperature and pressure, while the monoclinic form is only stable at higher temperatures. The monoclinic form is more soluble than the triclinic form, as it contains fewer hydrogen bonds between</p>

<p>4-Chlorocinnamide is an organochlorine compound that has been found to have antibacterial properties. It inhibits the shikimate pathway in bacteria, which is essential for bacterial growth. This molecule has been shown to bind with the cation channel of the nerve cells in the trigeminal nerve and inhibit their function. The inhibition of this channel leads to reduced sensitivity to pain. 4-Chlorocinnamide is also a precursor in the synthesis of stilbene derivatives, which are used as anticancer drugs.</p>

<p>N,3-Diphenylacrylamide is an amide that has been shown to exhibit carcinoid syndrome in humans. It also inhibits the growth of some human pathogens, including viruses and bacteria, as well as some fungi. The compound is metabolized by a number of enzymes and can be found circulating in the blood. Magnetic resonance spectroscopy has been used to study the structure of this molecule, which is composed of a carbonyl group and hydrogen bond. The effective dose for N,3-Diphenylacrylamide is not known.</p>

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<p>N-Methyl-N-vinylacetamide is a colorless liquid with a boiling point of 105.6°C. It is produced by the reaction of acetamide and vinyl chloride in the presence of hydrochloric acid, glycol ether, and methyl ethyl ketone. The viscosity of this compound is low, which makes it an ideal solvent for paints and coatings. N-Methyl-N-vinylacetamide also has genetic damaging effects and can cause mutations in bacteria that are exposed to this compound in high concentrations. This product has an unusual chemical structure due to its hydrogen bonding interactions.br&gt;br&gt;<br>br&gt;br&gt;<br>Hydrogen bonds are weak intermolecular forces between polar molecules, such as water or alcohols, that are formed by the attraction between a partially positive hydrogen atom on one molecule and the negative end of another nearby molecule. Hydrogen bonds stabilize certain molecular structures because they provide partial shielding from electrostatic interactions with</p>

<p>N-[2-(p-Cinnamylamino)ethyl]-5-isoquinolone sulfonamide is a high quality chemical that can be used as a reagent, complex compound, and useful intermediate. N-[2-(p-Cinnamylamino)ethyl]-5-isoquinolone sulfonamide is a fine chemical that is useful in the production of speciality chemicals. It can be used as a versatile building block and reaction component to produce various compounds.</p>

<p>N-[(8-Fluoro-2,3-Dihydro-1-Methyl-5-Phenyl-1H-1,4-Benzodiazepin-2-Yl)Methyl]-3-Furancarboxamide is a hydrophobic, implanting drug with an iontophoresis device. It has been shown to have therapeutic effects in cancer. The drug is a targetable molecule that can be used for diagnostic purposes and the treatment of various cancers. N-[(8-Fluoro-2,3-Dihydro-1,5 -Phenyl 1H -1,4 Benzodiazepin 2 Yl) Methyl] 3 Furancarboxamide has been shown to inhibit cell proliferation by blocking the synthesis of proteins required for DNA replication and also inhibits the activity of protein kinase C.</p>

<p>Voltage-gated sodium channel blocker</p>

<p>4-Amino-N-benzylbenzamide is a high quality chemical that is an intermediate in the synthesis of other useful compounds. It is a reagent for organic synthesis, and has many uses as a complex compound, as well as being a useful building block for more complicated molecules. 4-Amino-N-benzylbenzamide is also used as a speciality chemical in research labs, and can be used as a versatile building block to make different products.</p>

<p>Pigment Orange 36 is an organic pigment with a light-emitting property. It is soluble in organic solvents, such as benzene and chloroform, but insoluble in water. Pigment Orange 36 has a polycyclic aromatic hydrocarbon structure with ester linkages between the aliphatic hydrocarbon and aromatic hydrocarbon moieties. The molecule consists of two sections: one section is soluble in organic solvents and the other section is soluble in water. The particle size of Pigment Orange 36 ranges from 0.1 to 1 micron in diameter, and it emits light when excited by UV radiation or visible light.</p>

<p>2-Methylbenzamide is an amide with a carbonyl group and an intramolecular hydrogen. It has been shown to have synergic effects when combined with piperonyl butoxide in the treatment of autoimmune diseases. This synergistic effect is due to the inhibition of inflammatory mediator release, which can be achieved by blocking the enzyme cyclooxygenase-2. 2-Methylbenzamide has also been shown to inhibit deuterium isotope effect in cd-1 mice, which could make it beneficial for patients who are unable to tolerate other drugs.</p>

<p>2-(3-Hydroxyphenyl)acetamide (2HPA) is a sulfonamidochrysoidine compound with analgesic, antipyretic and anti-inflammatory effects. It is used in the treatment of gout, rheumatoid arthritis, osteoarthritis and other inflammatory diseases. 2HPA has been shown to be effective in the treatment of pain following dental surgery. 2HPA is also used as a marker for dietary intake of sulfate and may be a useful indicator for determining the effect of changes in diet on urinary excretion rates. The elimination half-life of 2HPA is approximately 3 hours in humans. This drug can be detected in urine samples from humans within 24 hours after ingestion at concentrations that are proportional to dose.</p>

<p>Heptadecafluoro-N,N-Bis(2-Hydroxyethyl)Octanesulphonamide is a lubricant that is used in the manufacture of polyester films. It is insoluble and has excellent compressive properties. This compound is soluble in both organic solvents and water, and can be applied as a transfer agent or to obviate the need for a separate lubricant. Heptadecafluoro-N,N-Bis(2-Hydroxyethyl)Octanesulphonamide is an inorganic material that does not react with other materials. It also has good deformation resistance and low hardness. The particle size of this compound is between 5 and 10 microns.</p>

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<p>Lacosamide is a drug that is used for the treatment of epilepsy. It has been shown to inhibit neuronal death in vitro and in animal models, and has been extensively studied for its potential benefits in the treatment of bowel disease. The mechanism of action for lacosamide involves inhibition of the transport of neurotransmitters from the synaptic cleft by binding to the neuronal sodium channels and increasing their recovery rate. Lacosamide has also been found to affect energy metabolism by inhibiting the activity of mitochondrial enzymes such as matrix effect and complex I/III.</p>

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<p>Anthranilamide is used for non-selective, efficient fluorescent labelling of glycans.</p>

<p>N-(n-Butyl)thiophosphoric triamide is a triamide herbicide that inhibits the plant enzyme fatty acid synthase. It has been shown to inhibit the uptake of glycol ethers, such as glycol esters, into plants by acting on the glycol ester hydroxyl group. This chemical also inhibits the synthesis of fatty acids in plants and reduces lipid content in perennial ryegrass and solanum tuberosum. N-(n-Butyl)thiophosphoric triamide also inhibits nitrous oxide emissions from wastewater treatment plants.</p>

<p>N-(2-Fluorophenyl)-N-[4-(4-methyl-1,3-thiazol-2-yl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]propanamide is a drug that is used for the treatment of cancer. This drug is hydrophobic and has a molecular weight of 455. It has been shown to be effective in treating cancer cells by binding to the cell membrane and inhibiting the proliferation of these cells. N-(2-Fluorophenyl)-N-[4-(4-methyl-1,3-thiazol-2-yl)-1-(2-thiophen-3-ylethyl)piperidin]-4-- yl]propanamide also inhibits tumor growth by reducing extracellular matrix production and inducing apoptosis in cancer cells. This drug has a fluorescent property and can be detected with an optical microscope at a</p>

<p>5-Methyl-2-nitrobenzamide is a compound that has antiproliferative activity and is used as an anticancer drug. This drug inhibits the polymerization of the protein tubulin in cancer cells, thereby inhibiting cell division. It also inhibits the growth of certain tumor cell lines in vitro. 5-Methyl-2-nitrobenzamide was found to inhibit the proliferation of human ovarian carcinoma cells by binding to DNA, preventing transcription and replication of genetic information. In addition, this agent binds to tubulin and prevents its polymerization, leading to inhibition of cell division.</p>

<p>Hexadecanamide is a reactive amide that has an optimum concentration of 1.5-2.0 M in water and a pH range of 3.0-8.0. Hexadecanamide is oxidized by an oxidation catalyst to form hexadecane, which can be analyzed by gas chromatography or high performance liquid chromatography. The oxidation reaction can be monitored under constant pressure conditions using electrochemical impedance spectroscopy. Hexadecanamide reacts with hydroxyl groups and fatty acids to form hexadecanoic acid, which can be analyzed using gas chromatography or high performance liquid chromatography. Hexadecanamide also reacts with viral life to form hexadecanoic acid, which can be analyzed using gas chromatography or high performance liquid chromatography.<br>Hexadecanamide has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit the production of pro-inflammatory cytokines such as histamine and leukotrienes</p>

<p>N-Methyl-4-pyridone-3-carboxamide is a nonnutritive sweetener that has been shown to have no effect on peroxisome proliferation. It also had no effect on the levels of fatty acids in rat cardiomyocytes and did not affect uv absorption. N-Methyl-4-pyridone-3-carboxamide binds to the receptor α subunit of the taste receptor and inhibits adenosine uptake, which may be responsible for its effects on depression. This compound also alters energy metabolism by inhibiting mitochondrial ATP production and glycolysis.</p>

<p>2,5-Dichlorobenzamide is a halogenated compound that inhibits topoisomerase and proteasome activity. It has been shown to be cytotoxic against cancer cells in vitro. 2,5-Dichlorobenzamide can also inhibit the growth of tuberculosis bacteria and may be used as an operational agent for weed control. The safety profile of this drug has not yet been fully determined. 2,5-Dichlorobenzamide is available in two crystalline forms, both of which are active with different degrees of potency.<br>2,5-Dichlorobenzamide is a hybridization inhibitor that inhibits the enzyme DNA gyrase and proteasome activity. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division.</p>

<p>L-Histidine beta-naphthylamide is an allosteric activator of the imidazole group of histidine. It has been shown to regulate sequences and functional groups in subtilisin. L-Histidine beta-naphthylamide binds to the benzyl ester and regulatory allosteric site on the enzyme, which is located between the active site and the substrate binding site. The binding of this molecule stabilizes a transition state intermediate that would otherwise be too reactive to form products.</p>

<p>(S)-2-Aminobutyramide hydrochloride is a strong acid that can be used in the synthesis of other compounds. It is made by dissociating acetic acid with hydrogen chloride, or by reacting ammonia with hydrochloric acid. (S)-2-Aminobutyramide hydrochloride is also known as 2-aminobutyric acid dihydrochloride and protonated aminobutyric acid. It can be used to synthesize many other compounds, including amino acids, pharmaceuticals, and polymers. The virulent properties of this compound make it useful for industrial purposes.</p>

<p>N-[2-Iodoethyl]trifluoroacetamide is a reactive alkylating agent that is used in the synthesis of biologically active molecules. It reacts with lysines, tryptic and other amino acids to form covalent bonds, which can be cleaved by hydrolysis. The compound also reacts with sulfhydryl groups to produce sulfonium ions, which react with the thiol group at position C6 on the sarcoplasmic reticulum Ca2+ -ATPase to inhibit muscle contraction. N-[2-Iodoethyl]trifluoroacetamide has been shown to cause allergic reactions in rats, mice, and guinea pigs. This drug has also been observed to have an effect on the central nervous system when administered at high doses.</p>

<p>2-Piperazin-1-ylacetamide hydrochloride is a drug that binds to the protein PCSK9, which transports cholesterol into cells. It blocks the transport of cholesterol and therefore lowers the level of cholesterol in blood. 2-Piperazin-1-ylacetamide hydrochloride is used for the treatment of bowel disease, atrial fibrillation (a type of irregular heartbeat), congestive heart failure, and as an anti-viral agent. This drug has been shown to reduce levels of LDL cholesterol by up to 60%. 2-Piperazin-1-ylacetamide hydrochloride has also been shown to be effective against cancers such as prostate cancer and inflammatory bowel disease.</p>

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<p>2-Chloro-N-(4-chlorophenyl)acetamide (2CPA) is an antimycobacterial agent that inhibits the growth of Mycobacterium tuberculosis. The antimycobacterial activity of 2CPA has been demonstrated in a dilution method, where it reduced the number of viable cells in cultures of M. tuberculosis and Mycobacterium smegmatis. The antimicrobial activity of 2CPA was confirmed using a fluorescence assay, which showed that this compound is active against M. tuberculosis H37Rv and M. smegmatis at concentrations above 0.1 mM. 2CPA also has a potent bactericidal effect on Staphylococcus aureus with an MIC value of 0.06 mg/mL at 30 minutes and is active against Enterococcus faecalis with an MIC value of 4 mg/mL at 30 minutes.</p>

<p>Nipecotamide is a water-soluble drug that inhibits the activity of α1-acid glycoprotein, which is a blood protein that regulates the concentration of hydrogen ions in the body. It has been shown to inhibit the growth of amyloid protein and decrease camp levels in erythrocytes. Nipecotamide is used as an inhibitor for infectious diseases, such as leprosy, tuberculosis, and malaria. The chemical structure of nipecotamide contains nitrogen atoms and an amide bond with carbonyl oxygens. It is also an inhibitor binding to hydrochloric acid and hydrogen bonds with amide groups.</p>

<p>N-Phenylhydrazinecarbothioamide is a chemical compound that is used in wastewater treatment. It is an organic molecule that is composed of hydrophobic and hydrophilic parts. The hydrophobic part, which contains the phenyl group, binds to the hydrophobic region of the cell membrane and causes the cell to lyse. The hydrophilic part has an affinity for water and can be used as an electrode material in electrochemical impedance spectroscopy. N-Phenylhydrazinecarbothioamide also has been shown to have antibacterial properties against human pathogens, including Mycobacterium tuberculosis, Clostridium perfringens, and Escherichia coli O157:H7. The compound has been shown to inhibit cervical cancer cells by inhibiting protein synthesis through inhibition of ribosomal activity and fragmentation assay analysis showed that N-phenylhydrazinecarbothioamide binds to copper ions at a coordination geometry of</p>

<p>N-[(3S)-2,5-Dioxotetrahydro-3-furanyl]-2,2,2-trifluoroacetamide is a boronic acid that has been used to synthesize polymers. This compound is of interest for the synthesis of hydrophobic amino acids such as threonine and lysine. The high yield and functionalisation of this molecule make it deserving of further investigation.</p>

<p>2,2,2-Trifluoro-N-(4-piperidinyl)acetamide (TFAPA) is a nucleic acid analog that binds to the target nucleic acid. TFAPA is a morpholino compound with an amide linkage between the morpholine ring and the acetic acid group. TFAPA is a sequence-specific DNA analog that inhibits protein synthesis by binding to the target nucleic acid. TFAPA can also be used as a probe for the detection of abnormal sequences in RNA.</p>

<p>Dopamine (D2) receptor antagonist; 5-HT4 serotonin receptor agonist</p>

<p>COX inhibitor; non-steroidal anti-inflammatory drug</p>

<p>4-Chloro-3-nitrobenzamide (4CNBA) is a potent inducer of hepatic drug metabolizing enzymes. It reacts with methyl cinnamate to form the 4-chloro-3-nitrobenzamide methyl ester and chloride ions. This reaction is catalyzed by copper, which binds to the 4CNBA molecule. The chloride ion then displaces water from the ester, producing a nitroso intermediate. This intermediate breaks down into an unstable nitrite, which in turn reacts with hydrogen peroxide to form a hydroxylamine intermediate. Hydroxylamine can then react with sulfhydryl groups to produce reactive thiols that are responsible for the induction of detoxification enzymes in the liver.<br>4CNBA has been shown to be toxic at high concentrations and is rapidly detoxified by Phase II enzymes such as glutathione S transferase, UDP glucuronosyltransferase, and N-acetyl</p>

<p>Chemically a chlorinated salicylanilide, niclosamide is clinically used as an anthelmintic agent. The action of niclosamide has been proven to proceed by inhibiting the STAT3 signaling pathway. Recently, niclosamide, has been considered as an antiproliferative agent in cancer treatment, e.g. melanoma and colorectal cancer. In 2021, niclosamide has been tested for the treatment of COVID-19 patients.</p>

<p>N-Benzylbenzamide is a molecule that contains an amide group, which is considered to be a hydrogen bond acceptor. The amine group of this compound can also act as a hydrogen bond donor. It has been shown to inhibit the activity of tyrosinase, which is an enzyme responsible for the production of melanin in melanocytes. N-Benzylbenzamide has been shown to have a molecular mechanism similar to that of hydroquinone and other phenolic compounds. In addition, it has been found to decrease microvessel density and inhibit the growth of cancer cells in vitro. This compound is not yet approved for use as a drug but may be used in future research studies as an alternative treatment for cancer.</p>

<p>Tenofovir alafenamide fumarate is a prodrug of tenofovir, an active antiretroviral agent. Tenofovir binds to the viral polymerase and blocks the synthesis of viral DNA. Tenofovir alafenamide fumarate is a prodrug that undergoes hydrolysis to form tenofovir. It has been shown to inhibit growth factor-β1, which may reduce the risk of opportunistic infections in people with HIV or AIDS. Tenofovir alafenamide fumarate has also been shown to be effective as an antiviral prophylaxis when used in combination with other drugs for active antiretroviral therapy.</p>

<p>4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide is an amide that is used to treat HIV infections. It has been shown to have potent anti-viral activity against HIV infected cells in the laboratory and can inhibit the replication of HIV by interfering with the virus's ability to use the reverse transcriptase enzyme. 4ABAB has been shown to bind to the enzyme ribonuclease H (crth2), which is responsible for breaking down viral RNA. This binding prevents crth2 from cleaving viral RNA, thus inhibiting DNA synthesis and preventing cell death. 4ABAB also interferes with a hydrogen bond between ethyl group and the hydroxyl group on crth2, leading to a decrease in activity.</p>

<p>2-Chloro-N-(3,5-dichlorophenyl)acetamide is a stabilized, crystalline compound. It has a planar structure with an amide bond and hydrogen bonds. The 2-chloro group is bonded to the nitrogen atom of the acetamide group. The 3,5-dichlorophenyl group is bonded to the carbon atom of the acetamide group. The chlorine atoms are in a planar configuration with adjacent chlorine atoms forming a skeletal arrangement. This chemical is used as an intermediate for other compounds.</p>

<p>N-[4-[1-(2-Fluorobenzyl)-3-butyl-2,6-dixo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]phenyl]acetamide is a fine chemical with a diverse range of potential applications. It can be used as a versatile building block in the synthesis of complex compounds and is useful as a reaction component or reagent. Its CAS number is 628279-07-2.</p>

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