Cannabinoids
Cannabinoids are a class of diverse chemical compounds derived from fatty acids or polyketides that act on cannabinoid receptors in cells, altering neurotransmitter release in the brain. Found primarily in cannabis plants, cannabinoids like THC and CBD are widely studied for their therapeutic effects, including pain relief, anti-inflammatory properties, and potential use in neurodegenerative diseases. At CymitQuimica, you will find a wide variety of cannabinoids for research in pharmacology, neurobiology, and medical chemistry.
Found 299 products of "Cannabinoids"
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GW 833972A hydrochloride
CAS:<p>A cannabinoid receptor agonist, which binds more selectively to CB2 than CB1 receptors (1000-fold). GW833972A inhibits vagus nerve depolarization induced by tussive agents, such as hypertonic saline (EC50 = 6.5 μM), capsaicin (EC50 = 33.9 μM) or PGE2 (EC50 = 15.9 μM).</p>Formula:C18H13ClF3N5O·HClPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:444.24 g/mol1,2,3,9-Tetrahydro-4H-carbazol-4-one
CAS:<p>1,2,3,9-Tetrahydro-4H-carbazol-4-one is a cyclic ketone compound, which can be synthesized through various organic reactions involving appropriate precursors. It is often derived from indole-based substrates through catalytic hydrogenation, allowing the formation of its stable tetrahydro structure with a retained core carbazole skeleton.</p>Formula:C12H11NOPurity:Min. 95%Color and Shape:PowderMolecular weight:185.23 g/molC2
CAS:<p>Positive allosteric modulator (PAM) of cannabinoid receptors CB2. The C2 modulator is the first synthetic PAM of CB2 receptors with antinociceptive properties, which were observed in a mouse model of neuropathic pain.</p>Formula:C21H24BrFN2O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:435.33 g/molACEA, 5mg/ml solution in ethanol
CAS:<p>Cannabinoid type 1 (CB1) receptor agonist. Anti-depressant activity demonstrated in vivo alone, as well as enhancing the effect of fluoxetine. In the brain, ACEA activates CB1 receptors expressed in the mitochondria of neuronal cells to elicit neuroprotective effects. This is mediated by inducing glycogen synthase kinase-3β (GSK-3β) phosphorylation and inhibiting the opening of mitochondrial permeability transition pore (MPTP).<br>Sold by weight of solid</p>Formula:C22H36ClNOPurity:Min. 95%Color and Shape:Clear LiquidMolecular weight:365.98 g/molAnandamide
CAS:<p>Anandamide is an endogenous cannabinoid, which is a bioactive lipid mediator primarily found in the brain and peripheral organs. It is synthesized from membrane phospholipid precursors through enzymatic pathways, primarily involving the enzyme N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD). Anandamide acts as a ligand for cannabinoid receptors, mainly the CB1 receptor located in the central nervous system, and the CB2 receptor found in peripheral tissues.</p>Formula:C22H37NO2Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:347.53 g/molGW 833972A
CAS:<p>A cannabinoid receptor agonist, which binds more selectively to CB2 than CB1 receptors (1000-fold). GW833972A inhibits vagus nerve depolarization induced by tussive agents, such as hypertonic saline (EC50 = 6.5 μM), capsaicin (EC50 = 33.9 μM) or PGE2 (EC50 = 15.9 μM).</p>Formula:C18H13ClF3N5OPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:407.78 g/molCannabichromenic Acid
CAS:<p>Cannabichromenic acid is a non-psychoactive phytocannabinoid and a precursor of cannabichromene1 which toxicological and pharmacological properties are unknown. Due to its structural similarity to cannabichromene, it is thought to reportedly exert anti-analgesic and anti-inflammatory activity.</p>Formula:C22H30O4Purity:Min. 95%Molecular weight:358.47 g/molAPD 371
CAS:<p>A selective cannabinoid receptor type 2 (CB2) agonist. Commonly, CB2 agonists induce receptor internalization, which results in desensitization and tachyphylaxis. However, APD 371 mediates efficient recycling of internalized receptors back to the plasma membrane and thus sustains analgesic effects, upon subchronic treatment, in an osteoarthritis pain model in vivo.</p>Formula:C18H23N5O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:357.41 g/molCannabigerovarinic acid
CAS:Controlled Product<p>Cannabigerovarinic acid is a phytocannabinoid and the precursor to tetrahydrocannabivarinic acid, cannabidivarinic acid, and cannabichromevarinic acid1. No in vitro or in vivo pharmacological and toxicological studies have been conducted on cannabigerovarinic acid.</p>Formula:C20H28O4Purity:Min. 95%Molecular weight:332.43 g/molAbnormal 1''-Hydroxycannabidiol
Controlled ProductFormula:C21H30O3Color and Shape:NeatMolecular weight:330.4615-(4-Hydroxypentyl)-1,3-benzenediol
CAS:Controlled Product<p>Applications 5-(4-Hydroxypentyl)-1,3-benzenediol is an intermediate used in the synthesis of 4''-Hydroxycannabidiol (H824830), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 4''-Hydroxycannabidiol be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>Formula:C11H16O3Color and Shape:NeatMolecular weight:196.24Cannabigerovarinic acid
CAS:Carboxylic acid with phenol functionFormula:C20H28O4Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:332.43Dehydroabiethylamine
CAS:<p>Dehydroabiethylamine (NSC-2955) boosts liver CYP2B, blocks PDKs & cholesterol transport, and has anti-tumor effects.</p>Formula:C20H31NPurity:98.79%Color and Shape:Pale Yellow Viscous Liquid /Technical Grade/ Viscous Colorless To Amber LiquidMolecular weight:285.47UR-144 N-Pentanoic Acid
CAS:Controlled ProductFormula:C21H27NO3Color and Shape:NeatMolecular weight:341.441-(3,5-Bis(benzyloxy)phenyl)pentan-1-ol
CAS:Controlled ProductFormula:C25H28O3Color and Shape:NeatMolecular weight:376.491-(3,5-Bis(benzyloxy)phenyl)pent-1-en-3-one
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications (Z)-1-(3,5-Bis(benzyloxy)phenyl)pent-1-en-3-one is a reagent in the synthesis of 3''-Hydroxycannabidiol (H824825) which is a major constituents in marijuana. 3''-Hydroxycannabidiol be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>Formula:C25H24O3Color and Shape:NeatMolecular weight:372.46Ethyl 2-Oxopentanoate
CAS:Controlled Product<p>Applications Ethyl 2-oxopentanoate is used as a reagent to synthesize selective CB1 cannabinoid receptor antagonists. Ethyl 2-oxopentanoate is also used to synthesize derivatives of iminodiacid, an inhibitor of angiotensin converting enzyme.<br>References Lange, J., et al.: J. Med. Chem., 48, 1823 (2005); Vincent, M., et al.: Tetrahedron Lett., 23, 1677 (2982)<br></p>Formula:C7H12O3Color and Shape:NeatMolecular weight:144.17
