Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,519 products)
- Apoptosis(5,786 products)
- Cell Cycle/Checkpoint(4,444 products)
- Chromatin/Epigenetics(2,235 products)
- Cytoskeletal Signaling(1,382 products)
- DNA Damage/DNA Repair(2,823 products)
- Endocrinology/Hormones(3,499 products)
- Enzyme(3,639 products)
- GPCR/G-Protein(8,314 products)
- Immunology and Inflammation(3,516 products)
- Influenza Virus(296 products)
- JAK/STAT signaling(404 products)
- MAPK Signaling(1,199 products)
- Membrane Transporter/Ion Channel(2,786 products)
- Metabolism(9,417 products)
- Microbiology/Virology(6,967 products)
- Neuroscience(9,920 products)
- Other Inhibitors(37,931 products)
- Oxidation-Reduction(41 products)
- PI3K/Akt/mTOR Signaling(1,399 products)
- Proteases/Proteasome(1,596 products)
- Stem Cell and Derivatives(832 products)
- Tyrosine Kinase/Adaptors(2,015 products)
- Ubiquitination(1,646 products)
Show 16 more subcategories
Found 66627 products of "Inhibitors"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Anticancer agent 35
<p>Compound 10, a sulfonylurea, inhibits A549, A431, PACA2 cells with IC50s: 18.1, 4.0, 18.9 μg/mL.</p>Formula:C15H13N3O3S3Color and Shape:SolidMolecular weight:379.48NLRP3-IN-4
<p>NLRP3-IN-4 is an effective, oral NLRP3 inflammasome inhibitor with potent anti-inflammatory effects on colitis.</p>Formula:C22H22N2O5Color and Shape:SolidMolecular weight:394.42SSR-182289A (Free)
CAS:<p>SSR-182289A (Free) is a thrombin inhibitor.</p>Formula:C30H33F2N5O4SPurity:98%Color and Shape:SolidMolecular weight:597.68Antitumor agent-54
<p>Compound C11 inhibits 14-3-3η protein (KD: 35 μM), targets liver cancer cells, blocks G1-S phase, and induces apoptosis.</p>Formula:C29H32N2O3Color and Shape:SolidMolecular weight:456.58CI-1029
CAS:<p>CI-1029: HIV protease inhibitor, combats mutant strains, high efficacy, good bioavailability in animals.</p>Formula:C28H37NO4SColor and Shape:SolidMolecular weight:483.66NUCC-555
CAS:<p>NUCC-555 is a first-in-class antagonist of activin. It opens a completely new approach to inhibiting the activity of TGF-beta receptor superfamily members.</p>Formula:C25H25N5O3Purity:98%Color and Shape:SolidMolecular weight:443.5CEP-7055
CAS:<p>CEP-18770: oral proteasome inhibitor; blocks NF-kappaB; may cause cancer cell apoptosis; less toxic than bortezomib in normal cells.</p>Formula:C32H35N3O4Color and Shape:SolidMolecular weight:525.64BMS-066
CAS:<p>BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.</p>Formula:C19H21N7O2Purity:98%Color and Shape:SolidMolecular weight:379.42LY 245769
CAS:<p>LY 245769 is an inhibitor of leukotriene E4 (LTE4).</p>Formula:C25H33F3N8OSPurity:98%Color and Shape:SolidMolecular weight:550.64Tylophorinidine
CAS:<p>Tylophorinidine is an antifungal agent that has shown to inhibit cell growth.</p>Formula:C22H23NO4Color and Shape:SolidMolecular weight:365.42DS01080522
<p>DS01080522: PRKACA inhibitor, IC50: kinase 0.8 nM, CREB 66 nM; potential for cancer research.</p>Formula:C23H20Cl2N4O3Color and Shape:SolidMolecular weight:471.34Bulgecin A
CAS:<p>Bulgecin A is an inhibitor of binuclear metallo-beta-lactamases and Lytic transglycosolase.</p>Formula:C16H29N3O14S2Color and Shape:SolidMolecular weight:551.54SARS-CoV-2-IN-23
<p>SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1].</p>Formula:C21H22N2OColor and Shape:SolidMolecular weight:318.41MRK003
CAS:<p>MRK003, a γ-secretase inhibitor, induces apoptosis, halts cell growth in myeloma/NHL, and affects notch signaling and PI3K/Akt pathway.</p>Formula:C25H31F6N3O2SColor and Shape:SolidMolecular weight:551.59MtTMPK-IN-7
<p>MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.</p>Formula:C27H29ClN6O3Color and Shape:SolidMolecular weight:521.01BAY-693
CAS:<p>BAY-693 is a ERK5 negative control agent with IC50 (ERK5) = 6400 nM. Its analog, BAY-885, is a potent and selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM</p>Formula:C26H30F3N7O2Color and Shape:SolidMolecular weight:529.56Purine phosphoribosyltransferase-IN-1
<p>Compound (S,R)-48 inhibits Pf, Pv, & Tbr PRT with Ki of 50, 20, 2 nM.</p>Formula:C11H15N5Na4O10P2Color and Shape:SolidMolecular weight:531.17GSK8814
CAS:<p>GSK8814 is a selective and ATAD2/2B bromodomain chemical probe and inhibitor (binding constant pKd=8.1 and a pKi=8.9 in BROMOscan).</p>Formula:C28H35F2N5O3Purity:98%Color and Shape:SolidMolecular weight:527.61BI-207524
CAS:<p>BI-207524 is a novel NS5B Thumb Pocket 1 Inhibitor with Improved Potency for the Potential Treatment of Chronic Hepatitis C Virus Infection.</p>Formula:C35H36ClN5O5Color and Shape:SolidMolecular weight:642.14J-113397
CAS:<p>J-113397 is a potent and selective NOP receptor antagonist (IC50 = 2.3 nM).</p>Formula:C24H37N3O2Purity:98%Color and Shape:SolidMolecular weight:399.57Tezampanel hydrate
CAS:<p>Tezampanel is used for the treatment of migraine, neuropathic pain.</p>Formula:C13H23N5O3Color and Shape:SolidMolecular weight:297.35Aurora B inhibitor 1
CAS:<p>Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki <0.010 uM) with potential anticancer activity for cancer research.</p>Formula:C25H26ClF2N7O2Purity:98.37%Color and Shape:SolidMolecular weight:529.97SF0166
CAS:<p>SF0166: potent αvβ3 antagonist, IC50: 0.6 nM. Blocks cell adhesion, IC50: 7.6 pM-76 nM. Reduces neovascularization in mice.</p>Formula:C23H27F2N5O4Color and Shape:SolidMolecular weight:475.49JAK3-IN-11
CAS:<p>JAK3-IN-11: potent oral JAK3 inhibitor (IC50=1.7 nM), noncytotoxic, >588-fold selectivity, blocks T-cell growth; useful in autoimmune research.</p>Formula:C23H23N5O2Color and Shape:SolidMolecular weight:401.46PIKfyve-IN-1
<p>PIKfyve-IN-1: potent, cell-active inhibitor for PIKfyve research, IC50=6.9 nM.</p>Formula:C20H21N5Color and Shape:SolidMolecular weight:331.41Ro 0437626
CAS:<p>P2X1 purinergic receptor antagonist</p>Formula:C27H35N5O4SPurity:98%Color and Shape:SolidMolecular weight:525.66Aurora A inhibitor 1
CAS:<p>Aurora A inhibitor 1: potent, selective, targets cancer-linked Aurora A overexpression, potential for cancer research. (WO2021147974A1, 49)</p>Formula:C25H28ClF2N5O2Color and Shape:SolidMolecular weight:503.97CDK5-IN-2
CAS:<p>CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor that acts on CDK5/p25 (IC50: 0.2 nM) and CDK2/CycA (IC50: 23 nM).</p>Formula:C29H28FN5OColor and Shape:SolidMolecular weight:481.56Antifungal agent 39
CAS:<p>Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.</p>Formula:C23H22ClN3O5Color and Shape:SolidMolecular weight:455.89Aquayamycin
CAS:<p>Aquayamycin is an anthraquinone derivative and inhibitor of the enzyme tyrosine hydroxylase..</p>Formula:C25H26O10Color and Shape:SolidMolecular weight:486.47FTO-IN-5
CAS:<p>FTO-IN-5 is a potent, selective inhibitor targeting the fat mass obesity-associated protein (FTO).</p>Formula:C23H18Cl2N6O6Color and Shape:SolidMolecular weight:545.33Oleuroside
CAS:<p>Oleuroside can protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing.</p>Formula:C25H32O13Purity:98%Color and Shape:SolidMolecular weight:540.51Ledene
CAS:<p>Ledene (Viridiflorene) is an essential oil produced by viridiflorene synthase.</p>Formula:C15H24Purity:98%Color and Shape:SolidMolecular weight:204.35CGC 11150
CAS:<p>CGC 11150 is a polyamine analogue inhibit tumor growth in vitro and in vivo.</p>Formula:C40H100Cl10N10Color and Shape:SolidMolecular weight:1075.82Mifepristone methochloride
CAS:<p>Mifepristone methochloride is a glucocorticoid antagonist. This product will be sold for research use only.</p>Formula:C30H38ClNO2Color and Shape:SolidMolecular weight:480.08TP3011
CAS:<p>TP3011 is a potent topoisomerase I inhibitor equipotent as SN38 and is an active metabolite of CH-0793076.</p>Formula:C26H26N4O5Purity:98%Color and Shape:SolidMolecular weight:474.51C-11
CAS:<p>C-11 is a tubulin inhibitor and acts as an ADC cytotoxin with cytotoxicity for carcinoma cell lines.</p>Formula:C38H58N6O7SPurity:98%Color and Shape:SolidMolecular weight:742.97AZD-3199 dihydrobromide
CAS:<p>AZD-3199 dihydrobromide is a β2 adrenergic receptor agonist potentially for the treatment of asthma and chronic obstructive.</p>Formula:C32H44Br2N4O4SColor and Shape:SolidMolecular weight:740.59MK-7128
CAS:<p>MK-7128 is a CB1 receptor inverse agonist.</p>Formula:C29H25ClF2N4O2Color and Shape:SolidMolecular weight:534.98(-)-Adenophorine
CAS:<p>(-)-Adenophorine is a moderate alpha-l-fucosidase inhibitor.</p>Formula:C8H17NO4Color and Shape:SolidMolecular weight:191.22CBP/p300-IN-18
<p>CBP/p300-IN-18 (compound 8) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.056 μM) and LK2 H3K27 (IC50: 0.46 μM).</p>Formula:C25H27FN4O3Color and Shape:SolidMolecular weight:450.51XY153
<p>XY153 (8l) is a BD2 selective BET inhibitor targeting BRD4, 3 & 2 with IC50s: 0.79, 5.31 & 5.09 nM, useful in acute myeloid leukemia & cancer research.</p>Formula:C33H34FN3O4Color and Shape:SolidMolecular weight:555.64HP590
CAS:<p>HP590: potent oral STAT3 inhibitor, IC50=27.8 nM, blocks ATP, IC50=24.7 nM, hinders gastric cancer growth, triggers cell death.</p>Formula:C29H24F6N4O3Color and Shape:SolidMolecular weight:590.52Protectin D1
CAS:<p>Protectin D1 (Neuroprotectin D1) is a neuroprotectin produced by nerve cells and is a potential cardioprotective agent.</p>Formula:C22H32O4Purity:99.72% - 99.79%Color and Shape:SolidMolecular weight:360.49LY 541850
CAS:<p>LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human</p>Formula:C9H13NO4Purity:98%Color and Shape:SolidMolecular weight:199.2NR1H4 activator 1
CAS:<p>NR1H4 activator 1 is a potent and selective agonist of Famesoid X Receptor (FXR).</p>Formula:C34H53NO7SPurity:98%Color and Shape:SolidMolecular weight:619.85RDN2150
CAS:<p>RDN2150 (Compound 25), a ZAP-70 inhibitor with an IC50 of 14.6 nM, covalently binds to the C346 residue of ZAP-70, suppressing the expression of CD25 and CD69</p>Formula:C28H29ClN8O4Color and Shape:SolidMolecular weight:577.03Atiratecan
CAS:<p>Atiratecan (TP300), a CH0793076-based camptothecin prodrug, combats BCRP+/- tumors; doesn't affect AChE.</p>Formula:C31H34N6O6Purity:98%Color and Shape:SolidMolecular weight:586.64BTK-IN-16
CAS:<p>BTK-IN-16 is a potential inhibitor of wild-type BTK and C481S mutants.BTK-IN-16 can be used to study various autoimmune diseases and cancers caused by BTK.</p>Formula:C15H14N4O2Purity:99.04%Color and Shape:SoildMolecular weight:282.3GSK3368715
CAS:<p>GSK3368715 is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50s</p>Formula:C20H38N4O2Purity:98%Color and Shape:SolidMolecular weight:366.54FLT3/ITD-IN-1
<p>FLT3/ITD-IN-1 inhibits FLT3-ITD with IC50s: 38.2 nM (FLT3) and 144.1 nM (ITD), and fights acute myeloid leukemia.</p>Formula:C19H22N6O2Color and Shape:SolidMolecular weight:366.42OUN58101
CAS:<p>OUN58101, also MDK-8101/BI-D, is an RSV L-protein inhibitor with no formal name, first reported in patent WO 2005042530.</p>Formula:C32H36N6O6Color and Shape:SolidMolecular weight:600.66ZK159222
CAS:<p>ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.</p>Formula:C32H48O5Purity:98%Color and Shape:SolidMolecular weight:512.72Homodestcardin
CAS:<p>Homodestcardin: cyclic depsipeptide from T. roseum with immunosuppressant properties; inhibits mouse T cell proliferation.</p>Formula:C32H55N5O7Color and Shape:SolidMolecular weight:621.81(S)-MALT1-IN-5
CAS:<p>(S)-MALT1-IN-5: Potent MALT1 protease inhibitor, may help in abnormal T/B-cell signalling and MALT1-linked diseases.</p>Formula:C17H17ClF2N6O3Color and Shape:SolidMolecular weight:426.80BRL-42715
CAS:<p>BRL-42715 is an effective inhibitor of bacterial beta-lactamases.</p>Formula:C10H7N4NaO3SPurity:98%Color and Shape:SolidMolecular weight:286.24Casuarinin
CAS:<p>Casuarinin, an ellagitannin found in pomegranates and certain Casuarina/Stachyurus plants, is a carbonic anhydrase inhibitor and astringent.</p>Formula:C41H28O26Color and Shape:SolidMolecular weight:936.65NNC 55-0396
CAS:<p>NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.</p>Formula:C30H40Cl2FN3O2Purity:99.00%Color and Shape:SolidMolecular weight:564.56VEGFR-2-IN-13
<p>VEGFR-2-IN-13 (Compound 19a) is a potent VEGFR-2 inhibitor (IC50: 3.4 nM). vEGFR-2-IN-13 arrests the HepG2 cell cycle in G2/M phase and induces apoptosis.</p>Formula:C24H18N6O2SColor and Shape:SolidMolecular weight:454.5Casein Kinase II Inhibitor IV Hydrochloride
CAS:<p>Casein Kinase II Inhibitor IV HCl promotes keratinocyte differentiation, potential for skin disorder therapy.</p>Formula:C24H24ClN5O3Purity:98%Color and Shape:SolidMolecular weight:465.93Deleobuvir
CAS:<p>Deleobuvir(BI207127) is an inhibitor of non-nucleoside hepatitis C virus NS5B polymerase for the treatment of hepatitis C.</p>Formula:C34H33BrN6O3Color and Shape:SolidMolecular weight:653.57BMS-986143
CAS:<p>BMS-986143: oral BTK inhibitor, IC50=0.26 nM, potential for autoimmune research, also targets TEC, BLK, BMX, TXK, YES1, ITK.</p>Formula:C31H24Cl2N4O4Color and Shape:SolidMolecular weight:587.45Cap-dependent endonuclease-IN-17
CAS:<p>CEN inhibitor IN-17 targets influenza A/H3N2; IC50: 1.29 μM. From patent CN112898346A, DSC701.</p>Formula:C24H20F2N3O7PSColor and Shape:SolidMolecular weight:563.47IACS-8779
CAS:<p>IACS-8779 is a potent STING agonist that efficiently stimulates interferon gene activity and exhibits strong systemic antitumor effects.</p>Formula:C21H25N9O10P2S2Purity:98%Color and Shape:SolidMolecular weight:689.55FT001
CAS:<p>FT001: Oral BET Bromodomain inhibitor, IC50=0.46μM, suppresses MYC, anti-cancer, effective in vitro/vivo.</p>Formula:C25H29N3O4SPurity:99.9%Color and Shape:SolidMolecular weight:467.58Tubulin polymerization-IN-35
<p>Tubulin-IN-35 inhibits oxazolylisoindole microtubule formation, targeting VL51 marginal zone lymphoma.</p>Formula:C31H35N3O5Color and Shape:SolidMolecular weight:529.63UH 301
CAS:<p>UH 301 is a 5-HT1A receptor antagonist.</p>Formula:C16H24FNOColor and Shape:SolidMolecular weight:265.37Carbonic anhydrase inhibitor 2
CAS:<p>Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.</p>Formula:C12H16N4O6SColor and Shape:SolidMolecular weight:344.34Chitin synthase inhibitor 6
<p>Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.</p>Formula:C24H25N3O6Color and Shape:SolidMolecular weight:451.47TAI-95
CAS:<p>TAI-95 is an inhibitor of highly expressed cancer protein 1 (Hec1).</p>Formula:C24H23N5O3S2Color and Shape:SolidMolecular weight:493.60CVT-5440
CAS:<p>CVT-5440 is a selective, high-affinity (2B) adenosine receptor antagonist with good selectivity.</p>Formula:C27H28N6O5Color and Shape:SolidMolecular weight:516.55GDC-0339
CAS:<p>GDC-0339: oral Pim kinase inhibitor for multiple myeloma (Kis: Pim1 - 0.03 nM, Pim2 - 0.1 nM, Pim3 - 0.02 nM), well-tolerated.</p>Formula:C20H22F3N7OSColor and Shape:SolidMolecular weight:465.5(Rac)-BI 703704
CAS:<p>(Rac)-BI 703704 is a potent activator of soluble guanylyl cyclase (sGC).</p>Formula:C32H37N3O4SPurity:98%Color and Shape:SolidMolecular weight:559.72Glutaminyl Cyclase Inhibitor 3
CAS:<p>Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.</p>Formula:C24H32N6O2SPurity:98%Color and Shape:SolidMolecular weight:468.61PDE4-IN-14
CAS:<p>PDE4-IN-14 (Compound 1) serves as an inhibitor of phosphodiesterase 4 (PDE4), applicable in research concerning diseases associated with PDE4, including</p>Formula:C19H20F2N4O3SColor and Shape:SolidMolecular weight:422.45Ici D1542
CAS:<p>Ici D1542: potent TXS inhibitor & TXA2 receptor antagonist, effective thromboxane blocker in vitro.</p>Formula:C25H30N2O7Purity:98%Color and Shape:SolidMolecular weight:470.51Pyripyropene A
CAS:<p>Pyripyropene A is a potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2)(IC50 of 0.07 μM).</p>Formula:C31H37NO10Purity:98%Color and Shape:SolidMolecular weight:583.63TAS-117 hydrochloride
<p>TAS-117 HCl: potent oral Akt inhibitor (Akt1 IC50: 4.8nM, Akt2: 1.6nM, Akt3: 44nM), boosts anti-myeloma effects, induces cell death.</p>Formula:C26H25ClN4O2Color and Shape:SolidMolecular weight:460.96Heparastatin
CAS:<p>Heparastatin is an inhibitor of heparanase.</p>Formula:C8H11F3N2O5Purity:98%Color and Shape:SolidMolecular weight:272.18AS2521780
CAS:<p>AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).</p>Formula:C30H41N7OSPurity:98%Color and Shape:SolidMolecular weight:547.76EGFR-IN-38
CAS:<p>EGFR-IN-38: low-toxic acrylamide-derived EGFR inhibitor, targets NSCLC, patented for research on EGFR mutation-related diseases.</p>Formula:C25H24ClN7O2Color and Shape:SolidMolecular weight:489.96YM 202074
CAS:<p>metabotropic glutamate receptor type 1 (mGlu1) antagonist</p>Formula:C56H72N8O16S2Purity:98%Color and Shape:SolidMolecular weight:1177.34Motuporin
CAS:<p>Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac).</p>Formula:C40H57N5O10Color and Shape:SolidMolecular weight:767.91β-Glucuronidase/hCAII-IN-2
<p>β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.</p>Formula:C31H23NO8Color and Shape:SolidMolecular weight:537.52NS2B/NS3-IN-3
CAS:<p>NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .</p>Formula:C19H21N3O2Color and Shape:SolidMolecular weight:323.39STING agonist-7
<p>STING agonist-7 is an agonist of non-nucleotide STING that binds selectively to mouse STING but not human STING [1].</p>Formula:C17H12N4O4Color and Shape:SolidMolecular weight:336.3AX15910
<p>AX15910 is a potent inhibitor of BRD4 and ERK5.</p>Formula:C32H38N6O3Color and Shape:SolidMolecular weight:554.7CK2-IN-3
<p>CK2-IN-3: potent, selective CK2 inhibitor; Kd=12 nM, IC50: 1.51 μM (CK2α), 7.64 μM (CK2α'). For cancer research.</p>Formula:C22H26N4O7Color and Shape:SolidMolecular weight:458.46BNTX maleate
CAS:<p>δ1 opioid receptor antagonist</p>Formula:C31H31NO8Purity:98%Color and Shape:SolidMolecular weight:545.58LY2934747
CAS:<p>LY2934747 is a novel, potent, and systemically bioavailable mGlu2/3 receptor agonist, exhibiting both antipsychotic and analgesic properties in vivo.</p>Formula:C10H13NO4Color and Shape:SolidMolecular weight:211.21LY3020371 hydrochloride
CAS:<p>LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.</p>Formula:C15H16ClF2NO5SColor and Shape:SolidMolecular weight:395.81Pelecopan
CAS:<p>Pelecopan (BCX9930), an oral complement factor D inhibitor, prevents hemolysis in PNH (IC50=14.3 nM).</p>Formula:C23H19FN2O4Color and Shape:SolidMolecular weight:406.41Xylarianaphthol-1
CAS:<p>Xylarianaphthol-1 is an activator of p21 promoter in a p53-independent manner.</p>Formula:C16H20BrFN2O2Color and Shape:SolidMolecular weight:371.24Lysyllysyllysine
CAS:<p>Lysyllysyllysine is a cationic moiety. It may be used in the construction of gene delivery vectors and DNA nanoparticles.</p>Formula:C18H38N6O4Purity:98%Color and Shape:SolidMolecular weight:402.53Elongation factor P-IN-1
<p>EFP-IN-1: potent β-lysine derivative, inhibits EFP, slows E. coli growth.</p>Formula:C14H31N3O2Color and Shape:SolidMolecular weight:273.41XP5
<p>XP5 is an oral HDAC6 inhibitor, potent against cancer cells, including YCC3/7 (IC50=31 nM to 2.31 μM).</p>Formula:C19H25N3O5SColor and Shape:SolidMolecular weight:407.48EGFR/BRAF-IN-1
<p>EGFR/BRAF-IN-1 inhibits EGFR/BRAF (BRAFV600E IC50: 45 nM, GI50: 35 nM) and has antioxidant properties.</p>Formula:C26H28ClN3O4Color and Shape:SolidMolecular weight:481.97PARP-1-IN-1
<p>PARP-1-IN-1: Selective, oral PARP-1 inhibitor with 0.96 nM IC50; well-tolerated and effective in single-dose MDA-MB-436 model.</p>Formula:C23H25FN4OColor and Shape:SolidMolecular weight:392.47PPARγ agonist 2
<p>PPARγ agonist 2 is a highly effective compound that acts as a partial agonist for PPARγ.</p>Formula:C24H20O5Color and Shape:SolidMolecular weight:388.41Stauprimide
CAS:<p>Stauprimide inhibits MYC by blocking NME2, reducing MYC transcription in ESCs.</p>Formula:C35H28N4O5Purity:98%Color and Shape:SolidMolecular weight:584.62GSK945237
CAS:<p>GSK945237 is a type IIA topoisomerase inhibitor, effective on Gram-positive and negative bacteria, with favorable pharmacokinetics and in vivo efficacy.</p>Formula:C24H26FN5O3Color and Shape:SolidMolecular weight:451.49Dyrk1A-IN-1
<p>Dyrk1A-IN-1 is a triple inhibitor of Dyrk1A kinase activity, aggregation of tau and α-syn oligomers, with an IC50 value of 119 nM for Dyrk1A kinase.</p>Formula:C23H20N4O3SColor and Shape:SolidMolecular weight:432.49DSM705 hydrochloride
<p>DSM705 hydrochloride: potent antimalarial, pyrrole-based DHODH inhibitor effective against Plasmodium, non-toxic to mammalian DHODH.</p>Formula:C19H20ClF3N6OColor and Shape:SolidMolecular weight:440.85ABT-072
CAS:<p>ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.</p>Formula:C24H27N3O5SPurity:98%Color and Shape:SolidMolecular weight:469.55Hsp90-IN-16
<p>Hsp90-IN-16, a selective HSP90 inhibitor, targets HER2+ cancers with 6 μM IC50 in HCC1954 cells, blocking client proteins and inducing apoptosis.</p>Formula:C30H26FN3O6Color and Shape:SolidMolecular weight:543.54MGAT2-IN-1
CAS:<p>MGAT2-IN-1 is an orally active monoacylglycerol acyltransferase (MGAT2)inhibitor (human and mouse MGAT2 with IC50 of 7.8 and 2.4 nM , respectively).</p>Formula:C27H21ClF5N7O3SColor and Shape:SolidMolecular weight:654.01Hesperadin hydrochloride
<p>Hesperadin hydrochloride is an ATP-competitive indolone inhibitor of Aurora A and B, with an IC50 value of 250 nM for Aurora B.</p>Formula:C29H33ClN4O3SColor and Shape:SolidMolecular weight:553.12KRAS G12D inhibitor 11
CAS:<p>KRAS G12D inhibitor 11 targets KRAS G12D in cancer research (patent WO2021108683A1, compound 52).</p>Formula:C29H38BN5O3Color and Shape:SolidMolecular weight:515.45GSK 932121
CAS:<p>GSK 932121: potent antimalarial, targets P. falciparum by inhibiting cytochrome bc1 in the electron transport chain.</p>Formula:C20H15ClF3NO4Purity:98%Color and Shape:SolidMolecular weight:425.79DNA-PK-IN-6
CAS:<p>DNA-PK-IN-6 inhibits DNA-PKcs, disrupting tumor DNA repair and triggering apoptosis; enhances radiotherapy and targets various tumors (WO2021197159A1).</p>Formula:C19H21N7OColor and Shape:SolidMolecular weight:363.42JNJ-1250132
CAS:<p>JNJ-1250132 is a steroidal progesterone receptor modulator that inhibits binding of the receptor to DNA in vitro.</p>Formula:C33H41NO4Color and Shape:SolidMolecular weight:515.68CHK-IN-1
CAS:<p>CHK-IN-1 is a dual inhibitor of CHK1 and CHK2 with antiproliferative activity.</p>Formula:C18H19ClFN5OSPurity:>99.99%Color and Shape:SolidMolecular weight:407.89Tubulin inhibitor 16
<p>Tubulin inhibitor 16 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 16 exhibits cytotoxicity in HepG2 cells [1].</p>Formula:C16H12FNO2Color and Shape:SolidMolecular weight:269.27Carbonic anhydrase inhibitor 3
<p>Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].</p>Formula:C15H17N3O3SColor and Shape:SolidMolecular weight:319.38PHGDH-IN-2
<p>PHGDH-IN-2: potent PHGDH inhibitor, IC50=5.2μM; hinders PHGDH cancer cell growth & serine synthesis in MDA-MB-468.</p>Formula:C22H20N4O3SColor and Shape:SolidMolecular weight:420.48MB725
CAS:<p>MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation.</p>Formula:C18H21IN4O2SColor and Shape:SolidMolecular weight:484.35ZBH-1205
CAS:<p>ZBH-1205, a camptothecin derivative, shows strong antitumor effects via apoptosis, outperforming cpt-11 and sn38 in topoisomerase-1 inhibition.</p>Formula:C29H31N3O8Color and Shape:SolidMolecular weight:549.57SIK1 activator 1
CAS:<p>SIK1 activator 1 boosts SIK1 phosphorylation, reduces type 2 diabetes hyperglycemia, and inhibits liver gluconeogenesis.</p>Formula:C23H32O6Color and Shape:SolidMolecular weight:404.50CCG258208
CAS:<p>GRKs-IN-1 has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).</p>Formula:C24H25FN4O4Purity:98%Color and Shape:SolidMolecular weight:452.48AMG-25
CAS:<p>AMG-25 (c-Kit-IN-5-1) is a c-Kit inhibitor that inhibits c-Kit, KDR, p38, Lck, and Src, and can be used for the study of mast cell-associated fibrotic diseases.</p>Formula:C23H17N5O2Purity:98.16%Color and Shape:SolidMolecular weight:395.41MAO A/HDAC-IN-1
<p>MAO A/HDAC-IN-1 is an effective monoamine oxidase A (MAO A) and HDAC dual inhibitor, which can be used for glioma research.</p>Formula:C21H24ClN3O3Color and Shape:SolidMolecular weight:401.89JBIR-22
CAS:<p>JBIR-22 is a natural inhibitor for protein−protein interaction of the homodimer of proteasome assembly factor 3.</p>Formula:C23H33NO6Color and Shape:SolidMolecular weight:419.51Antiviral agent 7
<p>Antiviral agent 7 is a peptide-based coating that kills viruses.</p>Formula:C29H31F2N3O6Color and Shape:SolidMolecular weight:555.57J-104118
CAS:<p>J-104118 potentially inhibits squalene synthase.</p>Formula:C28H26Cl2FNO5Purity:98%Color and Shape:SolidMolecular weight:546.41Cav 2.2/3.2 blocker 1
<p>Compound 9e is a Cav 2.2/3.2 blocker; IC50: 1.22 μM & 80 μM, respectively; penetrates CNS.</p>Formula:C28H30N2O3Color and Shape:SolidMolecular weight:442.55MsbA-IN-1
<p>MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.</p>Formula:C23H18Cl2FNO3Color and Shape:SolidMolecular weight:446.3Lumirubin
CAS:<p>Lumirubin is a water-soluble photoproduct of bilirubin formed in vivo during phototherapy.</p>Formula:C33H36N4O6Color and Shape:SolidMolecular weight:584.66CH5447240
CAS:<p>CH5447240: potent hPTHR1 agonist, treats Hypoparathyroidism, EC50 12 nM, 55% oral bioavailability, raises rat serum calcium.</p>Formula:C26H39N5O4SPurity:98%Color and Shape:SolidMolecular weight:517.68AXKO-0046
<p>AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.</p>Formula:C25H33N3Color and Shape:SolidMolecular weight:375.55AFP-07 free acid
CAS:<p>AFP 07 free acid is a 7,7-difluoroprostacyclin derivative. It also acts as a selective and highly potent agonist for the IP receptor.</p>Formula:C22H30F2O5Purity:98%Color and Shape:SolidMolecular weight:412.47AChE/BChE-IN-3 hydrochloride
<p>AChE/BChE-IN-3 (BMC-1) HCl is a dual inhibitor with IC50s: eqBChE 0.383 μM, elAChE 6.08 μM.</p>Formula:C15H25ClN2O3Color and Shape:SolidMolecular weight:316.82hA3AR agonist 1
<p>hA3AR agonist 1 is a potent human A 3 adenosine receptor (hA 3 AR) agonist (Ki = 2.40 nM) .</p>Formula:C10H14N6OSColor and Shape:SolidMolecular weight:266.32SLC4101431
<p>SLC4101431 is a potent SphK2 inhibitor with Ki value of 90 nM.</p>Formula:C29H28ClN7OSColor and Shape:SolidMolecular weight:558.1Heme Oxygenase-1-IN-2
<p>Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM.</p>Formula:C19H18ClN3OColor and Shape:SolidMolecular weight:339.8214,15-dehydro Leukotriene B4
CAS:<p>LTB4 is a leukocyte-activating fatty acid via 5-lipoxygenase. Two receptors, BLT1 and BLT2, bind it. 14,15-dehydro LTB4 is a stronger BLT1 antagonist.</p>Formula:C20H30O4Color and Shape:SolidMolecular weight:334.45SMP-797 HCl
CAS:<p>SMP-797 HCl, an ACAT (acyl-CoA-cholesterol acyltransferase) inhibitor, is used potentially for the treatment of Hyperlipidemia.</p>Formula:C34H44ClN5O4Purity:98%Color and Shape:SolidMolecular weight:622.20SDM25N hydrochloride
CAS:<p>δ receptor antagonist</p>Formula:C26H27ClN2O3Purity:98%Color and Shape:SolidMolecular weight:450.96(S)-5-hydroxy-6-methoxy Duloxetine maleate
<p>(S)-5-hydroxy-6-methoxy Duloxetine, an active metabolite of the (S)-duloxetine, functions as a serotonin (5-HT) and norepinephrine reuptake inhibitor.</p>Formula:C19H21NO3S·C4H4O4Color and Shape:SolidMolecular weight:459.51Squalamine lactate
CAS:<p>Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.</p>Formula:C37H71N3O8SPurity:98%Color and Shape:SolidMolecular weight:718.04WEHI-539
CAS:<p>WEHI-539 is a selective Bcl-XL inhibitor (IC50: 1.1 nM).</p>Formula:C31H29N5O3S2Purity:98%Color and Shape:SolidMolecular weight:583.72MRS2500
CAS:<p>MRS2500 is a highly potent and selective platelet P2Y1 receptor antagonist.</p>Formula:C13H18IN5O8P2Purity:98%Color and Shape:SolidMolecular weight:561.16Rezatapopt
CAS:<p>Rezatapopt (PC14586) is a p53 reactivator with antitumor activity for the study of locally advanced or metastatic solid tumors.</p>Formula:C28H31F4N5O2Purity:98.12%Color and Shape:SolidMolecular weight:545.57U91356
CAS:<p>U91356 is an agonist of the dopamine receptors.</p>Formula:C13H17N3OPurity:98%Color and Shape:SolidMolecular weight:231.29GSK579289A
CAS:<p>GSK579289A is an inhibitor of benzimidazole thiophene.</p>Formula:C26H27ClN4O3SPurity:98%Color and Shape:SolidMolecular weight:511.04Odiparcil
CAS:<p>Odiparcil is an orally active beta-d-thioxyloside analog.</p>Formula:C15H16O6SPurity:98%Color and Shape:SolidMolecular weight:324.35MIV-150
CAS:<p>MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).</p>Formula:C19H17FN4O3Purity:98%Color and Shape:SolidMolecular weight:368.36DI-404
CAS:<p>DI-404: Potent DCN1-UBC12 inhibitor, selectivity blocks cullin 3 neddylation, Kd=6.9 nM.</p>Formula:C35H45ClN6O6SPurity:98%Color and Shape:SolidMolecular weight:713.29Flutimide
CAS:<p>Flutimide: Endonuclease inhibitor, IC50 = 3μM, for research on acute respiratory diseases like influenza.</p>Formula:C12H18N2O3Color and Shape:SolidMolecular weight:238.28CS-0777
CAS:<p>CS-0777 is a potent, selective, and orally active S1P1 agonist (sphingosine 1-phosphate receptor modulator).</p>Formula:C21H31N2O5PColor and Shape:SolidMolecular weight:422.45PD-149163
CAS:<p>PD-149163: brain-penetrating, selective NTR1 agonist; shows pro-cognitive, anti-psychotic, anxiolytic effects.</p>Formula:C42H71N9O6Color and Shape:SolidMolecular weight:798.07EGFR-IN-48
<p>EGFR-IN-48: potent EGFR inhibitor, oral, IC50: 0.193-66.7 nM, blocks EGFR mutants & BaF3/PC-9 cell proliferation.</p>Color and Shape:SolidRN941
CAS:<p>RN941 is a highly potent Bruton's tyrosine kinase (BTK) inhibitor.</p>Formula:C34H34FN7O5Purity:98%Color and Shape:SolidMolecular weight:639.68Antibiotic MA 144M2
CAS:<p>Antibiotic MA 144M2, an anthracycline glycoside, targets gram-positive bacteria and tumors, derived from Streptomyces and aclacinomycin A conversion.</p>Formula:C42H55NO16Color and Shape:SolidMolecular weight:829.88PI3Kα-IN-8
<p>PI3Kα-IN-8 is a selective inhibitor of PI3Kα (IC50: 0.012 μM).</p>Formula:C26H27BrN4O2Color and Shape:SolidMolecular weight:507.42Equisetin
CAS:<p>Equisetin: a QSI from Fusarium equiseti, curbs P. aeruginosa virulence, fights Gram-positive bacteria & HIV-1 integrase; not antibacterial to Gram-negative.</p>Formula:C22H31NO4Purity:98%Color and Shape:SolidMolecular weight:373.49Hoe 892
CAS:<p>Hoe 892 is a stable thia-thimo-analogue of prostacyclin and acts as a platelet aggregation inhibitor.</p>Formula:C20H33NO4SColor and Shape:SolidMolecular weight:383.55Tasidotin hydrochloride
CAS:<p>Tasidotin hydrochloride, a dolastatin 15 analog, inhibits microtubule assembly and dynamics.</p>Formula:C32H59ClN6O5Purity:98%Color and Shape:SolidMolecular weight:643.30Antitumor agent-42
<p>Antitumor agent-42 inhibits microtubule multimerisation and NO release, exhibiting anti-angiogenic, colony-forming and apoptosis-inducing effects.</p>Formula:C24H19BrN2O8SColor and Shape:SolidMolecular weight:575.39hCAII-IN-4
CAS:<p>hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.</p>Formula:C31H23NO9Color and Shape:SolidMolecular weight:553.52JH295 hydrate
<p>JH295 hydrate: potent, irreversible Nek2 inhibitor (IC50 = 770 nM), selective, doesn't target Cdk1, Aurora B or Plk1.</p>Formula:C18H18N4O3Color and Shape:SolidMolecular weight:338.36CEP-14083
CAS:<p>CEP-14083: potent ALK inhibitor, effective in NPM/ALK T-cell lymphoma, binds ATP site; IC50=11 nmol/L, also inhibits insulin receptor, preclinical efficacy.</p>Formula:C31H30N6O2Color and Shape:SolidMolecular weight:518.61Microtubule inhibitor 2
<p>Microtubule inhibitor 2: potent, selective, oral, induces ferroptosis, strong antitumor effect.</p>Formula:C20H23NO7Color and Shape:SolidMolecular weight:389.4A 76889
CAS:<p>A 76889 is an inhibitor of HIV-1 protease.</p>Formula:C44H58N8O6Purity:98%Color and Shape:SolidMolecular weight:794.98Fosmanogepix
CAS:<p>Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.</p>Formula:C22H21N4O6PPurity:98%Color and Shape:SolidMolecular weight:468.40PCSK9-IN-17
CAS:<p>PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.</p>Formula:C16H19N5OSColor and Shape:SolidMolecular weight:329.42A1/A3 AR antagonist 1
<p>Compound 10 is a potent dual A1/A3 AR antagonist, with Ki values of 37.6 nM (hA1), 25.4 nM (hA3), and 1.47 nM (rA1), studied in renal, lung, and Alzheimer's.</p>Formula:C24H18N2O3SColor and Shape:SolidMolecular weight:414.48Thiolactomycin
CAS:<p>Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).</p>Formula:C11H14O2SPurity:98%Color and Shape:SolidMolecular weight:210.29Pexacerfont
CAS:<p>Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).</p>Formula:C18H24N6OPurity:99.77%Color and Shape:SolidMolecular weight:340.42Beloranib
CAS:<p>Beloranib is a fumagillin anticancer drug. Beloranib belongs to an angiogenesis inhibitor.</p>Formula:C29H41NO6Purity:98%Color and Shape:SolidMolecular weight:499.642R,4R-Sacubitril
CAS:<p>2R,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.</p>Formula:C24H29NO5Purity:98%Color and Shape:SolidMolecular weight:411.49AD5075
CAS:<p>AD5075 is a bioactive chemical.</p>Formula:C22H20N2O5SColor and Shape:SolidMolecular weight:424.47Menin-MLL inhibitor 4
CAS:<p>Menin-MLL inhibitor 4 has antitumor activity.Menin-MLL inhibitor 4 is an inhibitor of Menin- MLL (mixed-lineage leukemia protein) interaction .</p>Formula:C32H38FN7O3Purity:98%Color and Shape:SolidMolecular weight:587.69ABL-001-Amide-PEG3-acid
<p>ABL-001-Amide-PEG3-acid, an analogue to ABL-001, primarily serves as a labeled chemical or fluorescent probe.</p>Formula:C29H33ClF2N6O9Purity:98%Color and Shape:SolidMolecular weight:683.06Pulvomycin
CAS:<p>Pulvomycin is a protein biosynthesis inhibitor preventing ternary complex formation between elongation factor Tu, GTP, and aminoacyl-tRNA.</p>Formula:C47H66O13Purity:98%Color and Shape:SolidMolecular weight:839.032SHP2 IN-1
CAS:<p>SHP2 IN-1 is an allergic SHP2 (PTPN11) inhibitor(IC50 : 3 nM).</p>Formula:C18H22Cl2N6OSPurity:98%Color and Shape:SolidMolecular weight:441.38LY 190388
CAS:<p>LY 190388 is a penicillamine-containing enkephalin analog used as an mu receptor agonist with analgesia activity.</p>Formula:C30H41N5O7SPurity:98%Color and Shape:SolidMolecular weight:615.74SR 33805 oxalate
CAS:<p>Ca2+ channel antagonist</p>Formula:C34H42N2O9SPurity:98%Color and Shape:SolidMolecular weight:654.77T01-1
CAS:<p>T01-1, a derivative of camptothecin, is an anticancer agent demonstrating significant anti-proliferative activity.</p>Formula:C26H29N3O6SColor and Shape:SolidMolecular weight:511.59RS 61756-007
CAS:<p>RS 61756-007 is a selective thromboxane receptor (TP) agonist.</p>Formula:C23H28O5Purity:98%Color and Shape:SolidMolecular weight:384.47S-8510 phosphate
CAS:<p>S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).</p>Formula:C12H13N4O6PPurity:98%Color and Shape:SolidMolecular weight:340.23Elacestrant S enantiomer
<p>Elacestrant S enantiomer is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively.</p>Formula:C30H38N2O2Purity:98%Color and Shape:SolidMolecular weight:458.63(Rac)-Plevitrexed
CAS:<p>(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).</p>Formula:C26H25FN8O4Purity:98%Color and Shape:SolidMolecular weight:532.53α-Amylase-IN-1
CAS:<p>α-Amylase-IN-1 is an α-Amylase inhibitor (IC50: 0.5509 μM).</p>Formula:C18H18N2O3Purity:99.92%Color and Shape:SoildMolecular weight:310.35PF-03715455
CAS:<p>PF-03715455 is a potent p38 MAPK inhibitor, reducing TNFα in blood (IC50=1.7 nM) with selectivity for p38α, and may treat COPD.</p>Formula:C35H34ClN7O3S2Purity:98%Color and Shape:SolidMolecular weight:700.27PSMA-1007
CAS:<p>PSMA-1007 is a novel Glu-Ureido-type prostate-specific membrane antigen (PSMA) inhibitor.</p>Formula:C49H55FN8O16Color and Shape:SolidMolecular weight:1030.01MS8511
CAS:<p>MS8511: Selective, irreversible G9a/GLP inhibitor. IC50: 100 nM (G9a), 140 nM (GLP). Lowers H3K9me2, anti-proliferative. Useful in cancer/AD/PWS research.</p>Formula:C28H41N5O3Color and Shape:SolidMolecular weight:495.66AChE/BuChE-IN-3
CAS:<p>AChE/BuChE-IN-3 inhibits AChE (IC50: 0.65 μM), BuChE (IC50: 5.77 μM), crosses BBB, and hinders Aβ1-42 aggregation for Alzheimer's research.</p>Formula:C30H30F3N3O6Color and Shape:SolidMolecular weight:585.57Numidargistat
CAS:<p>CB-1158 is a potent and orally bioavailable inhibitor of arginase (IC50s: 86 and 296 nM for recombinant human arginase 1 and 2).</p>Formula:C11H22BN3O5Purity:98%Color and Shape:SolidMolecular weight:287.12M3258
CAS:<p>LMP7-IN-1 may used in the research of inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases and cancer, is an inhibitor of</p>Formula:C17H20BNO5Purity:98%Color and Shape:SolidMolecular weight:329.16SJF 8240
CAS:<p>c-MET degrader with foretinib linked to VHL ligand; reduces c-MET in 6h, hampers AKT, halts GTL16 cells (IC50=66.7nM), acts on exon-14-less c-MET.</p>Formula:C58H65F2N7O11SColor and Shape:SolidMolecular weight:1106.25Factor B-IN-4
CAS:<p>Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.</p>Formula:C27H32N2O4Color and Shape:SolidMolecular weight:448.55GGTI298
CAS:<p>GGTI298 is a potent GGTase I inhibitor; IC50 3μM for Rap1A, >20μM for Ha-Ras.</p>Formula:C27H33N3O3SPurity:98%Color and Shape:SolidMolecular weight:479.63TRβ agonist 1
CAS:<p>TRβ Agonist 1, a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, demonstrates an EC50 value of 21 nM.</p>Formula:C29H25FN2O8Color and Shape:SolidMolecular weight:548.52KRAS G12D inhibitor 16
CAS:<p>KRAS G12D inhibitor 16 targets KRAS G12D with IC50 of 0.7 nM and mutant form at 0.35 μM, useful in various cancer studies.</p>Formula:C32H39IN6O3Color and Shape:SolidMolecular weight:682.59SB 224289
CAS:<p>SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.</p>Formula:C32H32N4O3Purity:98%Color and Shape:SolidMolecular weight:520.62rel-SB-612111 hydrochloride
CAS:<p>NOP receptor antagonist</p>Formula:C24H30Cl3NOPurity:98%Color and Shape:SolidMolecular weight:454.86PSB 36
CAS:<p>A1 adenosine receptor antagonist</p>Formula:C21H30N4O3Purity:98%Color and Shape:SolidMolecular weight:386.49Balanol
CAS:<p>Balanol is an ATP-competitive Protein Kinase C and Protein Kinase A inhibitor.</p>Formula:C28H26N2O10Color and Shape:SolidMolecular weight:550.51Anticancer agent 36
<p>Compound 11: Sulfonylurea derivative, antimicrobial, anticancer; MIC 0.039-0.156 mg/mL; A549 IC50: 19.7 μg/mL, PC3 IC50: 11.9 μg/mL.</p>Formula:C21H17N3O3S2Color and Shape:SolidMolecular weight:423.51CYP1B1-IN-2
<p>CYP1B1-IN-2 (compound 9j) is a highly potent and selective inhibitor of CYP1B1, a cytochrome P450 enzyme. It exhibits an IC50 value of 0.52 nM [1].</p>Formula:C20H11F3O2Color and Shape:SolidMolecular weight:340.3
