Ketones and derivatives
Ketones are organic compounds that contain a carbonyl group (C=O) bonded to two carbon atoms, forming a structure where the carbonyl group is flanked by alkyl or aryl groups. In pharmacology, ketones are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Some ketones have anti-inflammatory, analgesic, and antimicrobial properties. Ketone derivatives include compounds in which the carbonyl group is modified, such as enols, which have applications in drug synthesis and as chemical intermediates in the production of other bioactive compounds. Ketone derivatives are used in the design of new medicines, including those for treating neurodegenerative diseases, metabolic disorders, and certain types of cancer, thanks to their specific effects on enzymes and cellular processes.
Found 2393 products of "Ketones and derivatives"
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Desmethyl Ketoprofen
CAS:Controlled Product<p>Impurity Ketoprofen EP Impurity B<br>Applications Desmethyl Ketoprofen (Ketoprofen EP Impurity B) shows antiinflammatory and analgesic activities. It can be used as neoplasm inhibitors and for treatment of angiogenesis-related disorders.<br>References Allais, A., et al.: Eur. J. Med. Chem., 9, 381 (1974).<br></p>Formula:C15H12O3Color and Shape:WhiteMolecular weight:240.25a-Terpinene (~90%)
CAS:Controlled ProductFormula:C10H16Purity:~90%Color and Shape:ColourlessMolecular weight:136.23trans-Capsaicin
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Artursson., et al.: J. Pharma. Sci., 73, 1507 (1984), Fu., et al.: Pharma. Res., 2000, 17, 100 (2000),<br></p>Formula:C18H27NO3Color and Shape:White To Off-WhiteMolecular weight:305.413,4,5-Trimethoxybenzoic Acid
CAS:<p>Applications A metabolite of Trimebutine (T795605(P)), which is an opioid receptor agonist and an antispasmodic.<br>References Dieks, H., et al.: J. Labelled Comp. Radiopharm., 28, 1093 (1990), Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C10H12O5Color and Shape:White To BeigeMolecular weight:212.20(S)-Naproxen Methyl Ester
CAS:<p>Impurity Naproxen EP Impurity E<br>Applications Naproxen (N377520) methyl derivative. Naproxen impurity. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) indicated for the treatment of pain, inflammatory conditions such as rheumatoid arthritis, and fever. The drug belongs to the 2-aryl propionic acid family of COX-1 and COX-2 inhibitors.<br>References Haddock, R., et al.: Xenobiotica, 14, 327 (1984), Jeremy, J., et al.: Drugs, 40, 53 (1990), Wadhwa, L., et al.: Int. J. Pharm., 118, 31 (1995),<br></p>Formula:C15H16O3Color and Shape:NeatMolecular weight:244.29rac Ketorolac-d4 (>90%)
CAS:Controlled Product<p>Applications Labelled Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rooks, W.H., et al.: Agents Actions, 12, 684 (1982), Guzman, A., et al.: J. Med. Chem., 29, 589 (1986), McQuary, H.J., et al.: Clin. Pharmacol. Ther., 39, 89 (1986),<br></p>Formula:C15H9D4NO3Purity:>90%Color and Shape:NeatMolecular weight:259.29rac Ketoprofen
CAS:Controlled Product<p>Applications Anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Formula:C16H14O3Color and Shape:NeatMolecular weight:254.283,5-Dimethylphenoxymethyloxirane
CAS:Controlled Product<p>Applications 3,5-Dimethylphenoxymethyloxirane is a reactant used in the preparation of thiiranes.<br>References Thirupathaiah, A., et. al.: Oriental J. Chem., 25, 771 (2009)<br></p>Formula:C11H14O2Color and Shape:NeatMolecular weight:178.233-Methylnonane-2,4-dione (>80%)
CAS:Controlled Product<p>Applications 3-Methylnonane-2,4-dione is a compound that possesses a butter-like and beany off flavour that is a result of flavour reversion of soya-bean oil. 3-Methylnonane-2,4-dione is also present in Japanese green tea and pressure-cooked hen meat.<br>References Farkaš, P., et al.: Food Chem., 60, 617 (1997); Guth, H. & Grosch, W.: Flav. Chem., No vol. given, 377 (1999); Kumazawa, K. & Masuda, H.: J. Agr. Food Chem., 47, 5169 (1999)<br></p>Formula:C10H18O2Purity:>80%Color and Shape:NeatMolecular weight:170.25p-Butyl Ibuprofen Sodium Salt
CAS:<p>Impurity Ibuprofen EP Impurity B<br>Applications p-Butyl Ibuprofen Sodium Salt (Ibuprofen EP Impurity B) is an Ibuprofen (I140000) impurity.<br>References Kalafut, P. et al.: J. Pharm. Biomed. Anal., 49, 1150 (2009); Kucera, R. et al.: J. Pharm. Biomed. Anal., 38, 609 (2005);<br></p>Formula:C13H17O2·NaColor and Shape:White To Off-WhiteMolecular weight:228.263-Carboxy-α-methylbenzeneacetic Acid(Ketoprofen Impurity)
CAS:<p>Impurity Ketoprofen EP Impurity C; Ketoprofen USP Compound C: (2-(3-Carboxyphenyl)propionic Acid)<br>Applications 3-Carboxy-α-methylbenzeneacetic Acid (Ketoprofen EP Impurity C) is a impurity of Ketoprofen (K200800). Ketoprofen USP Compound C: (2-(3-Carboxyphenyl)propionic Acid)<br>References Dvorak, J., et al.: J. Pharm. Biomed. Anal., 36, 625 (2004), Allegretti, M., et al.: J. Med. Chem., 48, 4312 (2005),<br></p>Formula:C10H10O4Color and Shape:Off-WhiteMolecular weight:194.18(R)-Apomorphine-d5 Hydrochloride (Major)
CAS:Controlled ProductFormula:C17H12D5NO2•HClColor and Shape:NeatMolecular weight:272.3636464’-Hydroxyacetophenone Oxime
CAS:Controlled Product<p>Impurity Paracetamol EP Impurity G<br>Applications 4’-Hydroxyacetophenone Oxime is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Sengupta, S., et al.: Metal. Based Drugs, 8, 293 (2002) (2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)<br></p>Formula:C8H9NO2Color and Shape:NeatMolecular weight:151.164-Acetamidophenyl β-D-Glucuronide Sodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 4-Acetamidophenyl β-D-Glucuronide is a major urinary metabolite of Acetaminophen (A161220) (Paracetamol) in human (1). Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis (2,3).<br>References (1) Johnston, D., et al.: J. Chem. Res., Synop., 12, 406 (1988)(2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)<br></p>Formula:C14H16NO8·NaColor and Shape:White To Light RedMolecular weight:349.27Nitrobenzene
CAS:Controlled Product<p>Applications Nitrobenzene is a compound that exhibits chromosomal genotoxicity against hamster lung cells, and has the potential to cause cancer in humans (1,2). Nitrobenzene is also used as a starting material to synthesize 4-Aminophenol (A618920) through catalytic hydrogenation (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Bonacker, D. et al.: Arch. Toxicol. 2004 Jan;78(1):49-57.2. Hsu, C. et al.: J. Environ. Sci. Health. C. Environ. Carcinog. Ecotoxicol. Rev. 2007 Apr-Jun;25(2):155-843. Rode, C. et al.: Org. Proc. Res. Dev. 1999 Nov;3(6), pp 465–470<br></p>Formula:C6H5NO2Color and Shape:Light YellowMolecular weight:123.11Terpinolene (~90%)
CAS:Controlled Product<p>Applications Terpinolene is a chemical constituent of essential oils found in many plant species and exhibits analgesic and anti-inflammatory properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Macedo, E. M., et al.: Braz J Med Biol Res. 49, S0100 (2016); Garcia, G., et al.: Molecules. 22, E921 (2017)<br></p>Formula:C10H16Purity:>85%Color and Shape:ColourlessMolecular weight:136.235'-Acetyl-2'-chloro-3-methyl-[1,1'-biphenyl]-4-carbaldehyde
CAS:Purity:98%Molecular weight:272.7300109863281rac-Trimethyl Ketoprofen (Mixture of (2’,3’4’) and (3’,4’,5’) Isomers)
Controlled ProductFormula:C19H20O3Color and Shape:NeatMolecular weight:296.361-(5-Hydroxy-2-methylphenyl)ethanone
CAS:Purity:95+%Color and Shape:SolidMolecular weight:150.1770019531253-Hydroxyacetaminophen-D3
CAS:Controlled Product<p>Applications 3-Hydroxyacetaminophen-d3 is deuterium labeled 3-Hydroxyacetaminophen (H714750). 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)<br></p>Formula:C82H3H6NO3Color and Shape:NeatMolecular weight:170.18(-)-O-Desmethyl Tramadol
CAS:Controlled Product<p>Applications A optically active metabolite of Tramadol.<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formula:C15H23NO2Color and Shape:White To Off-WhiteMolecular weight:249.35(S)-Naproxen Ethyl Ester
CAS:<p>Impurity Naproxen EP Impurity F<br>Applications Naproxen (N377520) ethyl derivative. Naproxen impurity.<br>References Haddock, R., et al.: Xenobiotica, 14, 327 (1984), Jeremy, J., et al.: Drugs, 40, 53 (1990), Wadhwa, L., et al.: Int. J. Pharm., 118, 31 (1995),<br></p>Formula:C16H18O3Color and Shape:NeatMolecular weight:258.31Acetaminophen Glutathione Disodium Salt
CAS:<p>Applications Acetaminophen Glutathione Disodium Salt is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3,4).<br>References (1) Chen, C., et al.: Xenobiotica, 30, 1019 (2000) (2) Ikeda, H., et al.: Biochem. J., 364, 563 (2002) (3) Aleksunes, L., et al.: Toxicol. Sci., 83, 44 (2005) (4) Elsby, R., et al.: J. Biol. Chem., 278, 22243 (2003)<br></p>Formula:C18H22N4Na2O8SColor and Shape:White To BrownMolecular weight:500.433-Methoxy Acetaminophen
CAS:<p>Applications 3-Methoxy Acetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C9H11NO3Color and Shape:NeatMolecular weight:181.19Capsaicin-d3 (E/Z-Mixture)
CAS:Controlled Product<p>Applications A representative lot is a 5:1 E:Z mixture.Labelled Capsaicin (C175680). Has been isolated from paprika and cayenne. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.Note this is a powerful irritant. One part in 100 000 can be tasted.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Molnar, et al.: Arzneim.-Forsch., 15, 718 (1965), Monsereenusorn,Y., et al.: Crit. Rev. Toxicol., 10, 321 (1982),<br></p>Formula:C18D3H24NO3Color and Shape:NeatMolecular weight:308.432′,4′,5′-Trifluoropropiophenone
CAS:Formula:C9H7F3OColor and Shape:Low Melting SolidMolecular weight:188.149N-Benzyl Hydroxymedetomidine
CAS:Controlled Product<p>Applications N-Benzyl Hydroxymedetomidine is an impurity of Medetomidine (M203250, HCl); an α2-adrenergic agonist, sedative, and analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996)<br></p>Formula:C20H22N2OColor and Shape:NeatMolecular weight:306.4rac N-Bisdesmethyl Tramadol, Hydrochloride
CAS:<p>Applications A metabolite of Tramadol.<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formula:C14H22ClNO2Color and Shape:NeatMolecular weight:271.78rac-Ketoprofen Tris Base Amide
CAS:Controlled Product<p>Applications rac-Ketoprofen Tris Base Amide is derived from rac Ketoprofen (K200800), which is an anti-inflammatory and analgesic.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990);<br></p>Formula:C20H23NO5Color and Shape:NeatMolecular weight:357.15762285(±)-Ketoprofen-d4 (propionic-d4 acid)
CAS:Controlled Product<p>Applications (±)-Ketoprofen-d4 (propionic-d4 acid) (CAS# 1219805-29-4) is a useful isotopically labeled research compound.<br></p>Formula:C162H4H10O3Color and Shape:NeatMolecular weight:258.31N-[4-[(4-Hydroxyphenyl)amino]phenyl]acetamide
CAS:<p>Stability Hygroscopic<br>Applications N-[4-[(4-Hydroxyphenyl)amino]phenyl]acetamide is used in the synthesis of lithographic plates.<br></p>Formula:C14H14N2O2Color and Shape:NeatMolecular weight:242.27rac Ketoprofen-13C,d3
CAS:Controlled Product<p>Applications Anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Formula:CC152H3H11O3Color and Shape:NeatMolecular weight:258.293-(1-Cyanoethyl)benzoic Acid
CAS:Controlled Product<p>Applications 3-(1-Cyanoethyl)benzoic Acid is an intermediate for the synthetic preparation of various pharmaceutical compounds. 3-(1-Cyanoethyl)benzoic Acid was used in studies examining the enantioselectivity of nitrile hydratases.<br>References Rzeznicka, K., et al.: App. Microbiol. Biotechnol., 85, 1417 (2010); Van Pelt. S., et al.: Org. Biomole. Chem., 9, 3011 (2011);<br></p>Formula:C10H9NO2Color and Shape:BeigeMolecular weight:175.18Acetaminophen Dimer-d6
CAS:Controlled Product<p>Applications Acetaminophen Dimer-d6 is deuterium labeled Acetaminophen Dimer (A161235). Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986)(3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)<br></p>Formula:C16H10D6N2O4Color and Shape:NeatMolecular weight:306.354-Nitrophenol
CAS:Controlled ProductFormula:C6H5NO3Color and Shape:Light YellowMolecular weight:139.11N-Nitroso Rac N-Desmethyl Tramadol
Formula:C15H22N2O3Color and Shape:Colourless To Light YellowMolecular weight:278.347Ref: 10-F506307
1gTo inquire2gTo inquire5gTo inquire10gTo inquire25gTo inquire100mgTo inquire250mgTo inquire500mgTo inquire4-Isobutylbenzoic Acid
CAS:<p>Applications 4-Isobutylbenzoic Acid is used in the studies for the identification of the degradation products and potential impurities in Ibuprofen. 4-Isobutylbenzoic Acid is also applied in the determination of related substances in dexibuprofen using HPLC.<br>References Dondoni, A., et al.: Farmaco, Edizione Pratica, 41, 237 (1986); Xie, L., et al.: Zhongguo Yaoshi, 19, 1088 (2016)<br></p>Formula:C11H14O2Color and Shape:NeatMolecular weight:178.232-(p-Tolyl)propionic Acid
CAS:Controlled Product<p>Impurity Ibuprofen EP Impurity D<br>Applications 2-(p-Tolyl)propionic acid (Ibuprofen EP Impurity D) is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.<br>References Jia, C., et al.: Science, 287, 1992 (2000), Yu, J., et al.: Org. Biomol. Chem., 4, 4041 (2006),<br></p>Formula:C10H12O2Color and Shape:White To Off-WhiteMolecular weight:164.202'-Chloroacetophenone
CAS:Purity:95.0%Color and Shape:Liquid, ClearMolecular weight:154.58999633789062Ketoprofen Acyl-β-D-glucuronide (Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Ketoprofen (K200800(P)), which is an anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skordi, E., et al.: Xenobiotica, 34, 1075 (2004); Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Formula:C22H22O9Color and Shape:NeatMolecular weight:430.40L-Lysine Clonixinate
CAS:<p>Applications L-Lysine Clonixinate is a non-morphinic andalgesic.<br>References Krymchantowski, A., et al.: Curr. Ther. Res., 64, 505 (2003), Di Girolamo, G., et al.: Brit. J. Pharmacol., 141, 1234 (2004),<br></p>Formula:C13H11ClN2O2·C6H14N2O2Color and Shape:Off WhiteMolecular weight:408.883′,5′-Dimethyl-4′-methoxyacetophenone
CAS:Formula:C11H14O2Purity:97.0%Color and Shape:SolidMolecular weight:178.231Trinexapac-ethyl
CAS:<p>Applications Trinexapac-ethyl<br></p>Formula:C13H16O5Color and Shape:WhiteMolecular weight:252.262-[4-(2-Methylpropenyl)phenyl]propionic Acid
CAS:<p>Applications 2-[4-(2-Methylpropenyl)phenyl]propionic Acid is a byproduct of Ibuprofen (I140000(P)), which is an anti-inflammatory drug.<br>References Sharma, K., et al.: Int. J. Environ. Sci. Tech., 16, 8315 (2019)<br></p>Formula:C13H16O2Color and Shape:Light YellowMolecular weight:204.26N-Demethyl Trimebutine-d5 Hydrochloride
CAS:Controlled Product<p>Applications The main bioactive labelled metabolite of Trimebutine.<br>References Miura, Y., et al.: Drug Metab. Dispos., 17, 455 (1989), Xue, L., et al.: Eur. J. Pharmacol., 294, 75 (1995), Roman, F., et al.: J. Pharmacol. Exp. Ther., 289, 1391 (1999), Kayser, V., et al.: Life Sci., 66, 433 (2000),<br></p>Formula:C21H22D5NO5·HClColor and Shape:NeatMolecular weight:414.931-(2,4-Bis(benzyloxy)-6-hydroxyphenyl)ethanone
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:348.39801025390625rac 1-Methoxy Ketorolac
CAS:Controlled Product<p>Applications An impurity of the analgesic Ketorolac (K235650).<br></p>Formula:C16H15NO4Color and Shape:NeatMolecular weight:285.29(-)-N,N-Bisdesmethyl Tramadol
CAS:Controlled Product<p>Applications A optically active metabolite of Tramadol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formula:C14H21NO2Color and Shape:NeatMolecular weight:235.32Medetomidine
CAS:<p>Medetomidine (MPV785 free base) is a selective α2-adrenoceptor agonist, with sedative and analgesic and vasoconstrictive hypoxic , in small animal anesthesia.</p>Formula:C13H16N2Purity:99.88%Color and Shape:SolidMolecular weight:200.28Acetaminophen-d3
CAS:Controlled Product<p>Applications Acetaminophen-d3 is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C82H3H6NO2Color and Shape:WhiteMolecular weight:154.18Acetaminophen-13C2, 15N1
CAS:Controlled Product<p>Applications Acetaminophen-13C2, 15N1 is doubly labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C613C2H915NO2Color and Shape:WhiteMolecular weight:154.14(S)-(+)-Ketoprofen-13C,d3
CAS:Controlled Product<p>Applications Labelled (S)-(+)-Ketoprofen (K200805). Anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Formula:CC15D3H11O3Color and Shape:NeatMolecular weight:258.29Nabumetone
CAS:Controlled Product<p>Applications Nabumetone is an anti-inflammatory and antibacterial agent (1). A non-steroidal anti-inflammatory prodrug used for treatment of inflammatory and degenerative rheumatic diseases.<br>References (1) Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006)<br></p>Formula:C15H16O2Color and Shape:NeatMolecular weight:228.291-Keto Ketorolac
CAS:Controlled Product<p>Impurity Ketorolac EP Impurity B; Ketorolac USP Related Compound C<br>Applications 1-Keto Ketorolac (Ketorolac EP Impurity B; Ketorolac USP Related Compound C) is a Ketorolac impurity. Ketorolac or ketorolac tromethamine is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives, often used as an analgesic.<br>References Mroszczak, E., et al.: Drug Metab. Dispos., 15, 618 (1987), Gillis, J., et al.: Drugs, 53, 139 (1997),<br></p>Formula:C14H11NO2Color and Shape:Light YellowMolecular weight:225.24rac-2’,4’,5’-Trimethyl Ketoprofen
CAS:Controlled Product<p>Applications rac-2,4’,5’-Trimethyl Ketoprofen is an impurity of Ketoprofen (K200800), an anti-inflammatory and analgesic agent.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Formula:C19H20O3Color and Shape:NeatMolecular weight:296.36Flufenamic Acid-d4
CAS:Controlled ProductFormula:C14H6D4F3NO2Color and Shape:NeatMolecular weight:285.25N-(1-Phenylethyl) Ibuprofen Amide(Mixture of 4 Diastereomers)
CAS:Controlled Product<p>Applications Ibuprofen (I140000) impurity, an anti-inflammatory compound.<br>References Rubin, A., et al.: J. Pharm. Sci., 74, 82 (1985), Tracy, T., et al.: Drug Metab. Dispos., 20, 322 (1992),<br></p>Formula:C21H27NOColor and Shape:WhiteMolecular weight:309.45N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide
CAS:Controlled Product<p>Impurity Acetaminophen Impurity B<br>Applications N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide is an impurity of Acetaminophen (A161220), which is an analgesic and antipyretic (1,2,3,4). N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide may be a useful reagent to investigate mechanisms related to liver and kidney damage from acetaminophen. Acetaminophen Impurity B.<br>References (1) Potter, D. W. and Hinson, J. A.: Drug Metab Rev. 20, 341 (1989) (2) Potter, D. W. and Hinson, J. A.: J. Biol. Chem. 260, 12174 (1985) (3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(4) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C16H16N2O4Color and Shape:NeatMolecular weight:300.31trans-Capsaicin-d3
CAS:Controlled Product<p>Applications Labelled Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Artursson., et al.: J. Pharma. Sci., 73, 1507 (1984), Fu., et al.: Pharma. Res., 17, 100 (2000),<br></p>Formula:C18H24D3NO3Color and Shape:NeatMolecular weight:308.433-Ethylbenzophenone
CAS:Controlled Product<p>Applications 3-Ethylbenzophenone is the photodegradation product of Ibuprofen (I40000) and Ketoprofen (K200800)in aqueous solutions.<br>References Alapi, T., et al.: J. Photochem. Photobiol., 188, 409 (2007), Musa, K., et al.: Med. Chem., 50, 1735 (2007),<br></p>Formula:C15H14OColor and Shape:NeatMolecular weight:210.272′-Fluoro-5′-(trifluoromethyl)propiophenone
CAS:Formula:C10H8F4OPurity:≥97%Color and Shape:LiquidMolecular weight:220.167(R)-(-)-Ketoprofen
CAS:Controlled Product<p>Applications Anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Formula:C16H14O3Color and Shape:NeatMolecular weight:254.283-Acetylbenzophenone
CAS:<p>Impurity Ketoprofen EP Impurity A; Ketoprofen USP Related Compound D<br>Applications 3-Acetylbenzophenone (Ketoprofen EP Impurity A) is a Ketoprofen intermediate. Ketoprofen USP Related Compound D.<br>References Dvorak, J., et al.: J. Pharm. Biomed. Anal., 36, 625 (2004), Zhang, X., et al.: Bioorg. Med. Chem. Lett., 14, 1205 (2004),<br></p>Formula:C15H12O2Color and Shape:Off-White To Light YellowMolecular weight:224.253-Hydroxyacetaminophen
CAS:Controlled Product<p>Applications 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)<br></p>Formula:C8H9NO3Color and Shape:NeatMolecular weight:167.16Acetaminophen (1 mg/mL in Methanol)
CAS:Controlled ProductFormula:C8H9NO2Color and Shape:Single SolutionMolecular weight:151.16rac 2-(4-Formylphenyl)propionic Acid (Ibuprofen Impurity K)
CAS:<p>Impurity Ibuprofen EP Impurity K<br>Applications rac 2-(4-Formylphenyl)propionic Acid (Ibuprofen EP Impurity K) is a degradation product of Ibuprofen arising from oxidative and thermal treatments. Ibuprofen impurity K.<br>References Heikkinen, L., et al.: Acta Pharm. Fenn., 92, 275 (1983), Vargas, F., et al.: Pharmazie, 11, 767 (1991), Lee, J., et al.: Pharm. Res., 9, S170 (1995),<br></p>Formula:C10H10O3Color and Shape:White To Light YellowMolecular weight:178.184-Acetylamino-2-chlorophenol
CAS:Controlled Product<p>Impurity Paracetamol EP Impurity C/ Acetaminophen impurity C<br>Applications 4-Acetylamino-2-chlorophenol is an impuirty of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C8H8ClNO2Color and Shape:White To Light PurpleMolecular weight:185.61Acetaminophen-cysteine
CAS:Controlled ProductFormula:C11H14N2O3SColor and Shape:NeatMolecular weight:254.31Ketoprofen Ethyl Ester
CAS:Controlled Product<p>Applications Ketoprofen ethyl ester is an impurity of Ketoprofen (K200800).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Borodkin, S., et al.: J. Pharm. Sci., 59, 481 (1970), Shanbag, V., et al.: J. Pharm. Sci., 81, 149 (1991), Khan, M., et al.: Eur. J. Med. Chem., 40, 371 (2005),<br></p>Formula:C18H18O3Color and Shape:ColourlessMolecular weight:282.33Acetaminophen Dimer
CAS:<p>Applications Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986) (3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)<br></p>Formula:C16H16N2O4Color and Shape:NeatMolecular weight:300.314,5-Dimethyl-2-methoxyacetophenone
CAS:Formula:C11H14O2Purity:95.0Color and Shape:SolidMolecular weight:178.231Acetaminophen Glutathione-d3 Disodium Salt (~90%)
CAS:Controlled ProductFormula:C18H19D3N4Na2O8SPurity:~90%Color and Shape:Off-White To Dark BrownMolecular weight:503.45(R)-Apomorphine-10-sulfate
CAS:Controlled ProductFormula:C17H17NO5SColor and Shape:NeatMolecular weight:347.39Ethyl-(5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic
CAS:<p>Ethyl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic) is a molecule that can be used in the treatment of cardiac diseases. It is a cardiotonic agent that has been shown to shorten the duration of ventricular fibrillation and restore contractility. This drug also decreases the frequency and severity of angina pectoris and enhances coronary artery blood flow. The most effective dose for this drug is 1.5 mg per kg body weight. It is administered orally or intravenously and should not be used with fatty esters because it may cause hypotension. Ethyl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic) has been shown to have an effect on metal coordination profiles as well as an activated form of the molecule.</p>Formula:C17H17O3NPurity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:283.32 g/molParacetamol Impurity L
<p>Paracetamol Impurity L is a drug product that is used as an analytical standard for the impurity paracetamol. It is found in pharmaceuticals, such as acetaminophen, which is used to relieve pain and reduce fever. Paracetamol Impurity L is a natural compound and has been shown to be metabolically stable in humans. The CAS number for this compound is 619-25-4.</p>Formula:C16H16N2O4Purity:Min. 95%Molecular weight:300.31 g/molAcetaminophen acetate
CAS:<p>Acetaminophen acetate is a cholinergic amine that binds to the active site of the enzyme acetylcholine esterase, preventing it from breaking down acetylcholine. Acetaminophen is used as a pain reliever and antipyretic agent. It is also used for its anti-inflammatory effects in the treatment of rheumatoid arthritis and other inflammatory conditions. Acetaminophen has been shown to have anticancer properties, which may be due to its ability to bind to cancer cells, inhibit their growth, and induce apoptosis. Acetaminophen acetate is also an acylation reaction product that can be isolated by liquid chromatography in phase with fluorescence properties.</p>Formula:C10H11NO3Purity:Min. 95%Color and Shape:White PowderMolecular weight:193.2 g/mol5-Benzoyl-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-2,3-dihydro-1H-pyrrolizine-1-carboxamide, racemic
CAS:<p>5-Benzoyl-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-2,3-dihydro-1H-pyrrolizine-1-carboxamide is a drug product that is used in research and development. It is a synthetic compound with niche applications. It has been shown to be metabolized in animal studies and the metabolism pathways have been elucidated. The analytical impurity standard for this drug product is 5-(benzoylamino)-N-[2-(hydroxymethyl)propanoyl]-2,3,-dihydro-1H-pyrrolizine-1 -carboxamide. This compound can be custom synthesized and also has an HPLC standard available.</p>Formula:C19H22N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:358.39 g/mol5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS:<p>5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic is a drug product that is used for the research and development of drugs. It is manufactured synthetically. This compound has been shown to be metabolized in rats and humans. Studies have also shown that this compound may be an impurity in other drugs. The use of 5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic can be found in the USP/NF as a HPLC standard or as an analytical reference standard.</p>Formula:C15H12BrO3NPurity:Min. 95%Molecular weight:334.16 g/molMethyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic
CAS:<p>Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate is a particle that is used to treat cardiac arrhythmias. It has been shown to be effective as an antipyretic agent and may also have analgesic properties. Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate is a white powder that melts at temperatures of about 300°C. This drug can be administered by inhalation in the form of a vaporized liquid. The particle size of this drug is typically less than 10 microns in diameter. Methyl 5-benzoyl-2,3-dihydro-1H pyrrolizine 1 carboxylate can be administered through the respiratory tract as an aerosol or nebulizer. The molecular weight of this</p>Formula:C16H15NO3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:269.3 g/molAll-trans-retinol-d5
CAS:Controlled Product<p>All-trans-retinol-d5 is a supplement that is used to protect the brain from oxidative damage and to help maintain healthy skin. It is an antioxidant that prevents free radicals from damaging cells and helps maintain the structural integrity of cell membranes. All-trans-retinol-d5 can be found in high concentrations in animal tissues, such as liver, lung, kidney, heart, brain, and eye. It can also be found in human urine. The presence of all-trans-retinol-d5 in urine has been correlated with neuroprotective effects. Retinol levels have been shown to be higher in children who are less obese than those who are obese or overweight. All-trans retinol has been shown to inhibit cancer cell proliferation and induce apoptosis by inhibiting protein synthesis at the level of transcription.</p>Formula:C20H25D5OPurity:(%) Min. 80%Color and Shape:Clear Viscous LiquidMolecular weight:291.48 g/mol1-(4-Cyclopropylphenyl)ethanone
CAS:Formula:C11H12OPurity:97%Color and Shape:LiquidMolecular weight:160.2163′,5′-Dihydroxyacetophenone
CAS:Formula:C8H8O3Purity:96%Color and Shape:SolidMolecular weight:152.1491-(4-Ethylphenyl)ethanone
CAS:Formula:C10H12OPurity:95%Color and Shape:LiquidMolecular weight:148.2055′-Bromo-2′-hydroxy-4′-methylacetophenone
CAS:Formula:C9H9BrO2Purity:98%Color and Shape:SolidMolecular weight:229.0731-(4-Isopropoxyphenyl)ethanone
CAS:Formula:C11H14O2Purity:98%Color and Shape:Liquid, No data available.Molecular weight:178.2313′-Fluoro-5′-(trifluoromethyl)acetophenone
CAS:Formula:C9H6F4OPurity:98%Color and Shape:LiquidMolecular weight:206.14
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