Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10354 products of "Benzimidazole and Imidazole Derivatives"
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6-Desfluoro Rufinamide
CAS:Controlled Product<p>Applications 6-Desfluoro Rufinamide is an impurity in the synthesis of Rufinamide (R701550), an antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H9FN4OColor and Shape:NeatMolecular weight:220.20(2-Oxopyrrolidin-1-yl)acetic Acid
CAS:<p>Impurity Piracetam Impurity D<br>Applications (2-Oxopyrrolidin-1-yl)acetic acid is a reagent in the preparation of pyrazolopyridines as PDE4B inhibitors.<br>References Mitchell, C. J., et al.: Bioorg. Med. Chem. Lett., 20, 5803 (2010);<br></p>Formula:C6H9NO3Color and Shape:Off-WhiteMolecular weight:143.141-(2-Trifluoromethylphenyl)imidazole
CAS:Formula:C10H7F3N2Purity:98.0%Color and Shape:SolidMolecular weight:212.1754-Methoxy-2-(((6-methoxy-1H-benzo[d]imidazol-2-yl)sulfonyl)methyl)-3,5-dimethylpyridine 1-oxide
CAS:Purity:95.0%Molecular weight:377.42001342773443-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:293.32199096679695-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
CAS:Purity:95.0%Molecular weight:367.3699951171875Iminodibenzyl 5-Carbonyl Chloride
CAS:Controlled ProductFormula:C15H12ClNOColor and Shape:NeatMolecular weight:257.71Albendazole Sulfone
CAS:<p>Impurity Albendazole EP Impurity C / Albendazole Sulfone<br>Applications A metabolite of Albendazole, an anthelmintic. Albendazole EP Impurity C<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol. Lett., 6, 2: 51 (1996)<br></p>Formula:C12H15N3O4SColor and Shape:BeigeMolecular weight:297.334'-Ethoxyacetophenone
CAS:<p>Applications 4'-Ethoxyacetophenone, is an acetophenone derivative that can be used as an antibacterial agent. It is a reagent for plymerization. It can also be used as a flavoring agent in fabricating cigarettes with flavored filter tips.<br>References Sivakumar, P., et al.: Chem. Bio. Drug Design, 72, 303 (2008); Mathis, D. E., Beitraege zur Tabakforschung Int., 12, 1 (1983);<br></p>Formula:C10H12O2Color and Shape:White To Off-WhiteMolecular weight:164.202,2'-Bis(2-chlorophenyl)-4,4',5,5'-tetraphenyl-2'H-1,2'-biimidazole
CAS:Purity:98%Molecular weight:659.6099853515625Modafinil Sulfone
CAS:Controlled ProductFormula:C15H15NO3SColor and Shape:NeatMolecular weight:289.34952-Fluoro-1H-imidazole hydrochloride
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:122.52999877929688(R)-3-Boc-4-(Methoxymethylcarbamoyl)-2,2-dimethyloxazolidine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:288.3439941406252-Chloro-5-(2H-tetrazol-5-yl)-4-((thiophen-2-ylmethyl)amino)benzenesulfonamide
CAS:Purity:97.0%Color and Shape:LiquidMolecular weight:370.8299865722656(R)-4-Isopropyl-5,5-diphenyloxazolidin-2-one
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:281.3550109863281(1R)-(-)-10-Camphorsulfonic Acid
CAS:Controlled Product<p>Impurity Voriconazole EP Impurity E (1R)-Isomer<br>Stability Hygroscopic<br>Applications (1R)-(-)-10-Camphorsulfonic Acid (Voriconazole EP Impurity E (1R)-Isomer) is a chiral derivative of Camphor. Used in the preparation of a chiral recognition polymer that is used in the chiral separation of amino acids. A catalyst in direct animation of α-branched aldehydes (including important biological molecules such as α-Me phenylglycine) with near perfect enantioselectivity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Guo, H. et al.: Polym. Preprints Am. Chem. Soc., 40, 506 (1999); Liu, C. et al.: Org. Lett., 13, 2638 (2011);<br></p>Formula:C10H16O4SColor and Shape:WhiteMolecular weight:232.305,6-DIMETHYL-2-(PYRIDIN-3-YL)-1H-BENZO[D]IMIDAZOLE
CAS:Purity:95.0%Molecular weight:223.27900695800782,4-Diiodo-1H-imidazole
CAS:Purity:97.0%Color and Shape:Solid, Off-white to pale yellow solidMolecular weight:319.872009277343755-Methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:345.4200134277344(S)-N-((3-(4-(1,1-DIOXIDOTHIOMORPHOLINO)-3-FLUOROPHENYL)-2-OXOOXAZOLIDIN-5-YL)METHYL)ACETAMIDE
Purity:95.0%Molecular weight:385.41000366210942-Aminomethyl-7-chloro-2,3-dihydro-5-(2-fluorophenyl)-1H-1,4-benzodiazepine
CAS:Controlled Product<p>Applications An Intermediate for the synthesis of Midazolam.<br>References Walser, A., J. Org. Chem., 43, 936 (1978).<br></p>Formula:C16H15ClFN3Color and Shape:NeatMolecular weight:303.76Triclabendazole
CAS:Controlled Product<p>Applications An anthelmintic (fasciola).<br>References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)<br></p>Formula:C14H9Cl3N2OSColor and Shape:NeatMolecular weight:359.66Tioconazole
CAS:Controlled Product<p>Applications Tioconazole is an antifungal that is more active than Fluconazole (F421000) or Voriconazole (V760000) against Candida glabrata mutant strains. Antifungal (topical).<br>References Jevons, S., et al.: Antimicrob. Agents Chemother., 15, 597 (1979), Clayton, Y.M., et al.: Clin. Exp. Dermatol., 7, 543 (1982), Marriott, M.S., et al.: Dermatologica, 166, 1 (1983),<br></p>Formula:C16H13Cl3N2OSColor and Shape:WhiteMolecular weight:387.712-Mercapto-4,5,6,7-d4-benzimidazole
CAS:Controlled ProductFormula:C72H4H2N2SColor and Shape:NeatMolecular weight:154.23Climbazole-d4
CAS:Controlled ProductFormula:C15D4H13ClN2O2Color and Shape:Off White SolidMolecular weight:296.793-Hydroxy Carbamazepine
CAS:<p>Applications A metabolite of Carbamazepine (C175840).<br>References Park, B., et al.: Biochem. Pharmacol., 36, 581 (1987), Yamazaki, H., et al.: Drug Metab. Dispos., 27, 1260 (1999), Dieckhaus, C., et al.: Chem. Res. Toxicol., 14, 958 (2001),<br></p>Formula:C15H12N2O2Color and Shape:NeatMolecular weight:252.27Carbimazole
CAS:<p>Applications Carbimazole, a prodrug of Methimazole (M260300), is used in the treatment of hyperthyroidism.<br>References Marchant, B., et al.: J. Clin. Endocrinol. Metab., 45, 1187 (1977), Johnsson, E., et al.: Lancet, 350, 1520 (1997),<br></p>Formula:C7H10N2O2SColor and Shape:NeatMolecular weight:186.23Miconazole
CAS:<p>Applications Antifungal (topical).<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H14Cl4N2OColor and Shape:WhiteMolecular weight:416.13Thiabendazole-d4 (Major)
CAS:Controlled ProductFormula:C10D4H3N3SColor and Shape:Off WhiteMolecular weight:205.271,2-Phenylenediamine
CAS:Controlled Product<p>Stability Light and Mositure Sensitive<br>Applications An amino substituted benzene used in the manufacture of dyes. Potential use in sensitive immunosensor for cancer biomarker.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wu, Y. et al.: Anal. Bioanal. Chem., 400, 2141 (2011); Du, D. et al.: Anal. Chem., 82, 2989 (2010);<br></p>Formula:C6H8N2Color and Shape:White To Light YellowMolecular weight:108.142-(benzylthio)-1H-benzimidazole
CAS:Purity:95.0%Color and Shape:Solid, White powderMolecular weight:240.32000732421875[1-(3-phenoxypropyl)-1H-benzimidazol-2-yl]methanol
CAS:Purity:95.0%Molecular weight:282.3429870605469Omeprazole sulfide N-Oxide
CAS:<p>Applications 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole N-Oxide is a metabolite of Omeprazole (O635000), an proton inhibitor used as an antiulcerative agent.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O3SColor and Shape:Off-WhiteMolecular weight:345.42Tinidazole
CAS:Controlled Product<p>Applications Antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.<br>References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),<br></p>Formula:C8H13N3O4SColor and Shape:Off-White To Light YellowMolecular weight:247.272-(2-Aminoethyl)-1-methyl-1H-imidazole x 2 HCl
CAS:Formula:C6H13Cl2N3Purity:98.0%Color and Shape:Liquid, No data available.Molecular weight:198.092-Mercaptobenzimidazole
CAS:Controlled Product<p>Impurity Rabeprazole EP Impurity F<br>Applications An antidegradant, protecting rubber from oxidation. An intermediate in the synthesis of Rabeprazole (R070500)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Beheshti, A., et al.: J. Food Sci., 75, C135 (2010), Rohrig, U., et al.: J. Med. Chem., 53, 1172 (2010),<br></p>Formula:C7H6N2SColor and Shape:NeatMolecular weight:150.20NAP 226-90
CAS:<p>Impurity Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C<br>Applications NAP 226-90 (Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C) is a S-Enantiomer metabolite of Rivastigmine, a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Br. Med. J., 318, 633 (1999), Jann, M., et al.: Clin. Pharmacokinet., 41, 719 (2002), Frankfort, S., et al.: Int. J. Clin. Pract., 60, 646 (2006),<br></p>Formula:C10H15NOColor and Shape:WhiteMolecular weight:165.23Ethyl 2-(2-Oxopyrrolidin-1-yl)acetate (80%)
CAS:Controlled Product<p>Impurity Piracetam EP Impurity C<br>Applications Ethyl 2-(2-oxopyrrolidin-1-yl)acetate is a reagent in the preparation of N-substituted-2-oxopyrrolidinylacetamides which have anticonvulsant activities.<br>References Al-Obaid, A. M., et al.: Med. Chem. Res., 9, 696 (1999);<br></p>Formula:C8H13NO3Purity:80%Color and Shape:NeatMolecular weight:171.192-Methyl-4,5-diphenyloxazole
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:235.285995483398441-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester (>90%)
<p>Impurity Fesoterodine Impurity 6;<br>Applications 1-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester is derived from (R)-Fesoterodine Fumarate (F321300), which is a muscarinic receptor antagonist for the treatment of Lower Urininary Tract Symptoms (LUTS). It is very similar to Tolterodine (T535800).<br>References Rogers, D., et al.: Pharmacotherapy, 20, 1092 (2000), Praharaj, S., et al.: J. Psychopharmacology, 19, 426 (2005),<br></p>Formula:C26H35NO5Purity:>90%Color and Shape:NeatMolecular weight:441.562'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carbaldehyde
CAS:Purity:98%Molecular weight:250.26100158691406Secnidazole-d3
CAS:Controlled Product<p>Applications Labelled Secnidazole (S225000). Analog of Metronidazole. Antiamebic. Antiprotozoal (Trichomonas).<br>References Cosar, C., et al.: Arzneim.-Forsch., 16, 23 (1966), Videau, D., et al.: Br. J. Vener. Dis., 54, 77 (1978), Symonds, J., et al.: J. Antimicrob. Chemother., 5, 484 (1979),<br></p>Formula:C7H8D3N3O3Color and Shape:White To Off-WhiteMolecular weight:188.2Benzoylmetronidazole
CAS:Controlled Product<p>Applications Benzoylmetronildazole is a new class of antiglycation agents used to treat diabetes mellitus. Benzoylmetronildazole is also a derivative of Metronidazole (M338880), an antibacterial in the treatment of rosacea.<br>References Zeb, A., et al.: Med. Chem., 8, 846 (2012); Kumari, N., et al.: Curr. Drug. Deliv., 9, 74 (2012); Elosta, A., et al.: Curr. DIabetes. Rev., 8, 92 (2012);<br></p>Formula:C13H13N3O4Color and Shape:WhiteMolecular weight:275.26Scopolamine-13C, D3 Hydrobromide
CAS:Controlled Product<p>Applications Scopolamine-13C, d3 Hydrobromide, is the labeled analogue of Scopolamine-d3 Hydrobromide (S200002), an acetylcholine antagonist, used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),<br></p>Formula:C1613CH19D3BrNO4Color and Shape:Off-WhiteMolecular weight:388.284-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazole-2-carbaldehyde
CAS:Purity:99.0%Molecular weight:304.31298828125Midazolam-d6
CAS:Controlled Product<p>Applications Labelled Midazolam (M343000). Anesthetic; anticonvulsant; sedative; hypnotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000),<br></p>Formula:C18D6H7ClFN3Color and Shape:NeatMolecular weight:331.80Rufinamide-5-Carboxamide
CAS:Controlled Product<p>Applications Rufinamide-5-Carboxamide is an impurity of Rufinamide (R701550) which is an antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H8F2N4OColor and Shape:NeatMolecular weight:238.191’-Hydroxy Midazolam
CAS:Controlled Product<p>Applications A metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Midazolam is also a positive allosteric modulator of the GABAA receptor.<br>References Dundee, J., et al.: Drugs, 28, 519 (1984), Galetin, A., et al.: Drug Metab. Dispos., 30, 1512 (2002), Uchaipichat, V., et al.: Drug Metab. Dispos., 34, 449 (2006), Lewis, B., et al.: Biochem. Pharmacol., 73, 1463 (2007), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3OColor and Shape:Off-WhiteMolecular weight:341.772,2'-(OXYDIMETHANEDIYL)BIS(5-NITRO-1H-BENZIMIDAZOLE)
CAS:Purity:95.0%Molecular weight:368.30899047851563,4-Diaminoanisole
CAS:<p>Applications 3,4-Diaminoanisole (cas# 102-51-2) is a compound useful in organic synthesis.<br></p>Formula:C7H10N2OColor and Shape:NeatMolecular weight:138.171-Cyclopropyl-1H-benzo[d]imidazol-2(3H)-one
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:174.2030029296875Lansoprazole Sulfone
CAS:<p>Impurity Lansoprazole USP Related Compound A<br>Applications A metabolite of Lansoprazole, as gastric pump inhibitor. Lansoprazole USP Related Compound A.<br>References De Morais, S., et al.: Mol. Pharmacol., 46, 594 (1994), Spencer, C., et al.: Drugs, 48, 404 (1994), Pearce, R., et al.: J. Pharmacol. Exp. Ther., 277, 805 (1996), Tassaneeyakul, W., et al.: Br. J. Clin. Pharmacol., 49, 139 (2000),<br></p>Formula:C16H14F3N3O3SColor and Shape:NeatMolecular weight:385.364-Chloro-6-nitro-1,3-dihydro-2H-benzo[d]imidazol-2-one
CAS:Purity:98%Molecular weight:213.5800018310547Iminostilbene
CAS:Controlled Product<p>Impurity Carbamazepine EP Impurity D<br>Applications A metabolite of Carbamazepine (CBZ) (C175840).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lertratanangkoon, K., et al.: Drug Metab. Dispos., 10, 1 (1982), Deleu, D., et al.: Eur. J. Clin. Pharmacol., 57, 243 (2001),<br></p>Formula:C14H11NColor and Shape:Yellow To Dark OrangeMolecular weight:193.245-Amino-1,3-dihydro-benzoimidazol-2-one hydrochloride
CAS:Formula:C7H8ClN3OPurity:99.0%Color and Shape:PowderMolecular weight:185.61N-[3-(1H-imidazol-1-yl)propyl]-5,7-dimethyl-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:286.3999938964844Keto Itraconazole
CAS:Controlled ProductFormula:C35H36Cl2N8O5Color and Shape:NeatMolecular weight:719.627-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1,4-benzodiazepine 4-Oxide
CAS:Controlled Product<p>Applications 7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide is the synthetic precursor of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Laviana, L., et al.: J. Pharma. Biomed. Anal., 32, 167 (2003); Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C16H11ClFN3O3Color and Shape:NeatMolecular weight:347.732,4-Dichlorobenzyl Chloride
CAS:Controlled Product<p>Applications Reagent used in the addition of dichlorobenzene.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Marchand, P., et al.: Bioorg. Med. Chem., 17, 6715 (2009); Singh, J., et al.: J. Med. Chem., 53, 18 (2010);<br></p>Formula:C7H5Cl3Color and Shape:NeatMolecular weight:195.47Desnitro-imidacloprid Hydrochloride
CAS:Controlled ProductFormula:C9H11ClN4·ClHColor and Shape:Light Orange GreyMolecular weight:247.12(1R,3S,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl-2'-hydroxy-2',2'-di(thiophen-2''-yl)acetate
CAS:<p>Tanshinone IIA is an enantioselective hydroxamic acid that inhibits matrix metalloproteinase. It is a structural analogue of the hydroxamic acid Tanshinone I and has been shown to inhibit aggrecanase, which is an enzyme that hydrolyzes the glycosaminoglycan aggrecan. It also has anti-cancer effects due to its inhibition of cell proliferation in cancer cells. Tanshinone IIA can be used as a chiral synthon for polymerase chain reactions (PCR) because it contains a stereogenic centre in its structure.</p>Formula:C18H19NO3S2Purity:Min. 95%Color and Shape:PowderMolecular weight:361.48 g/mol2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
CAS:<p>2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].</p>Formula:C15H15N3OS2Purity:Min. 95%Molecular weight:317.43 g/molLansoprazole N-oxide
CAS:<p>Lansoprazole N-oxide is a prodrug that is converted to lansoprazole sulfone in vivo. Lansoprazole N-oxide is used as a diluent in chromatographic experiments. It has been shown to be more sensitive than the parent compound, lansoprazole, for the diagnosis of reflux oesophagitis. Lansoprazole N-oxide also has a validation wavelength of 240 nm and can be detected by liquid chromatography. The active form of lansoprazole, lansoprazole sulfone, can be detected by gas chromatography mass spectrometry (GCMS).</p>Formula:C16H14F3N3O3SPurity:Min. 95%Color and Shape:White PowderMolecular weight:385.36 g/mol5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole
CAS:<p>5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole is a natural product. It is an impurity in the drug development process and may be present as an analytical marker for impurities. 5-Methoxy-2-[(3,5-dimethylpyridinium)methyl]sulfinyl]-1Hbenzimidazole is used as a pharmacopoeia standard and can be synthesized on request.</p>Formula:C16H17N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:315.39 g/mol4-Desmethoxy omeprazole sulfide
CAS:<p>4-Desmethoxy omeprazole sulfide is a metabolite of omeprazole, a drug that is used to treat ulcers and gastroesophageal reflux disease. 4-Desmethoxy omeprazole sulfide is not an impurity in the production of omeprazole, but is present as a natural component of omeprazole. This compound has been shown to be an impurity standard for HPLC analysis. The pharmacopoeia defines 4-desmethoxy omeprazole sulfide as an API impurity in drug products. It is also being studied for its potential use in drug development and research and development.</p>Formula:C16H17N3OSPurity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:299.39 g/mol(R)-5-Hydroxymethyl tolterodine
CAS:<p>(R)-5-Hydroxymethyl tolterodine is a prodrug that is metabolized by cytochrome P450 3A4 (CYP3A4) in the liver to its active form, tolterodine. This drug can be used as an alternative for gabapentin in the treatment of detrusor muscle overactivity associated with neurogenic bladder dysfunction. The pharmacokinetic properties of (R)-5-hydroxymethyl tolterodine are similar to those of gabapentin, including the elimination half-life and volume of distribution. However, unlike gabapentin, which has been shown to increase the glomerular filtration rate (GFR) and renal blood flow, there is no evidence that this drug has any effect on GFR or renal blood flow. There is also no evidence that (R)-5-hydroxymethyl tolterodine causes any symptoms that may be attributed to</p>Formula:C22H31NO2Purity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:341.49 g/mol10,11-Dihydroxy-d10 Carbamazepine
Controlled Product<p>10,11-Dihydroxy-d10 Carbamazepine is a drug product that is used as an analytical reference standard. It is natural and synthetic impurity in the API (active pharmaceutical ingredient) Carbamazepine. The CAS number for 10,11-Dihydroxy-d10 Carbamazepine is 513-81-5. This compound has been synthesized by custom synthesis and is an impurity standard for HPLC analysis of carbamazepine. 10,11-Dihydroxy-d10 Carbamazepine is also a research and development chemical for the drug development industry. It has been classified as a niche chemical due to its high purity and pharmacopoeia grade.</p>Purity:Min. 95%(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS:<p>(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a drug used to treat depression. It is an antidepressant drug that inhibits the reuptake of serotonin and norepinephrine in the brain by blocking their transport into the nerve cells. The drug acts as a weak inhibitor of monoamine oxidase (MAO). It also has an effect on bladder function. This compound is synthesized from 1-phenyl-2,5-dihydrothiazole by way of a sequence of reactions that includes the formation of an amine salt via reaction with phosphorus pentoxide and chloroacetic acid followed by conversion to the chloride with thionyl chloride.</p>Formula:C15H15NPurity:Min. 95%Color and Shape:White PowderMolecular weight:209.29 g/mol2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt
<p>2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt is a white to off-white crystalline powder. It is soluble in water and sparingly soluble in alcohol. This product is used as an analytical standard and has been found to be a metabolite of the drug clozapine. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt has also been found to be an impurity in the drug product lamotrigine.</p>Formula:C24H29NO5•NaPurity:Min. 95%Molecular weight:434.49 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide is a cyclic sulfoxide that has shown to be a potent inhibitor of gastric acid secretion. It is an important intermediate in the synthesis of esomeprazole magnesium, a proton pump inhibitor used to treat gastroesophageal reflux disease and other gastrointestinal disorders. 5-Methoxy-2-[(4-methoxy 3,5 dimethyl 2 pyridinyl) methyl] sulphonyl]-1H benzimidazole N oxide is also known as (RS)-N-[4-(4′ methoxyphenyl)-3,5 dimethylpyrazol -2 - ylmethyl] methanesulfonamide. This compound has been shown to have a polymorphic form with two different</p>Formula:C17H19N3O5SPurity:Min. 95%Color and Shape:PowderMolecular weight:377.42 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole
CAS:<p>Omeprazole is a drug that belongs to the class of benzimidazole compounds. It is an inhibitor of gastric acid secretion in the stomach, reducing the production of hydrochloric acid and pepsin. Omeprazole has been shown to have greater chemical stability than other proton pump inhibitors (PPIs), with a higher solubility in water and a longer shelf life. Omeprazole also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Omeprazole also exhibits pharmacokinetic properties that are different from other PPIs. Omeprazole is rapidly absorbed following oral administration and has a high bioavailability, which can be attributed to its hydroxyl group. This hydroxyl group allows for esomeprazole (a prodrug) to be formed by hydrolysis in the gut or liver, increasing omeprazole's absorption and bioavailability.</p>Formula:C17H19N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:329.42 g/mol2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole
CAS:<p>2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole is a protonated sulfonamide that is used as an analytical method to detect the presence of other drugs in human liver tissue. It has been shown to inhibit the activity of cytochrome P450 3A4 (CYP3A4), one of the enzymes responsible for metabolizing many drugs. Bromoenol lactone and powder diffraction spectrum are two additional analytical methods that can be used to detect 2-[([(4-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole.</p>Formula:C18H21N3O4SPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:375.44 g/molAlbendazole sulfoxide
CAS:<p>Albendazole sulfoxide is a sulfoxide of albendazole. The molecular docking analysis of the two molecules showed that the sulfoxide group is located in the same position as the hydroxyl group on albendazole. It has been shown that this replacement of hydroxyl with a sulfoxide group increases the solubility and stability of albendazole, which may be due to hydrogen bonding interactions between these groups. Albendazole sulfoxide has been shown to be an effective treatment for infections caused by parasites such as helminths. However, it should not be used in combination with drugs that are metabolized by cytochrome P450 enzymes because it can inhibit their activity.</p>Formula:C12H15N3O3SPurity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:281.33 g/molN-Desmethyl galanthamine
CAS:Controlled Product<p>N-Desmethyl galanthamine is a plant alkaloid that is found in the Huperzia serrata plant. It has been shown to have cholinergic activity and calcium binding properties. N-Desmethyl galanthamine inhibits acetylcholinesterase, an enzyme responsible for the breakdown of acetylcholine, which is a neurotransmitter. This inhibition leads to increased levels of acetylcholine, which results in increased neuron stimulation and improved memory function. N-Desmethyl galanthamine also binds to β2 nicotinic receptor sites and blocks the binding of nicotine, leading to decreased nicotine dependence.</p>Formula:C16H19NO3Purity:Min. 95%Molecular weight:273.33 g/mol2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole
CAS:<p>Rabeprazole is a proton pump inhibitor that is used to treat acid-related disorders such as gastroesophageal reflux disease and peptic ulcers. Rabeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium ATPase that is found in the parietal cells of the stomach. The main mechanism of action for rabeprazole is competitive inhibition of the proton pump, which leads to decreased gastric acid secretion. Rabeprazole can be administered orally or intravenously, with a half-life of about 2 hours. It has been shown to have an effect on human liver cytochrome P450s, but does not affect the activity of recombinant cytochrome P450 3A4 (CYP3A4). In clinical studies, rabeprazole was shown to have no adverse effects on CYP3A4 activity and may even increase it slightly.</p>Formula:C18H21N3O2SPurity:Min. 95%Color and Shape:White PowderMolecular weight:343.44 g/molRabeprazole
CAS:<p>Rabeprazole is a proton pump inhibitor that suppresses the production of stomach acid by blocking the H+/K+ ATPase enzyme. It is used for the treatment of gastroesophageal reflux disease, peptic ulcers, and Zollinger-Ellison syndrome. Rabeprazole has been shown to be more effective than omeprazole in reducing gastric acid secretion in two-way crossover studies. Rabeprazole also has been shown to inhibit the growth of antibiotic-resistant strains of bacteria. In addition, rabeprazole binds to metal ions like iron and copper, which may affect its pharmacokinetics and efficacy. This drug is currently being investigated as an analytical method for determination of proton pump inhibitors in human serum and urine samples by electrochemical impedance spectroscopy (EIS).</p>Formula:C18H21N3O3SPurity:Min. 95%Color and Shape:White PowderMolecular weight:359.44 g/molPantoprazole sulphone
CAS:<p>Pantoprazole sulphone is a proton-pump inhibitor that inhibits the production of stomach acid and protects the esophagus from damage. Pantoprazole sulphone has been shown to be effective in treating heart disease patients and reducing their risk of death. It also has biological properties, including modulating the effects of bosentan, which is used to treat pulmonary arterial hypertension. Pantoprazole sulphone has been shown to be chemically stable and stereoselective, which means it binds more strongly to one site than another. Clinical pharmacology studies have found that pantoprazole sulphone has no effect on abomasal motility or gastric emptying time.</p>Formula:C16H15F2N3O5SPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:399.37 g/mol2-Mercaptobenzimidazole
CAS:<p>2-Mercaptobenzimidazole is a chemical compound that can be used for the treatment of infectious diseases. It has been shown to have antioxidative properties and inhibit the growth of bacteria. 2-Mercaptobenzimidazole also has an effect on human serum, which may be due to its ability to bind with proteins in serum and form hydrogen bonds. 2-Mercaptobenzimidazole is stable at high temperatures and has been shown as an effective antimicrobial agent against gram positive and gram negative bacteria.</p>Formula:C7H6N2SPurity:Min. 99 Area-%Color and Shape:White/Off-White SolidMolecular weight:150.19 g/molN-(2-Phenethyl)benzamide
CAS:<p>N-(2-Phenethyl)benzamide (NPEB) is a molecule that belongs to the group of reactive molecules. It has been shown to be toxic to gram-positive bacteria, such as Staphylococcus aureus and Bacillus subtilis, but not gram-negative bacteria such as Escherichia coli. NPEB also has been shown to have locomotor activity in animals, which may be due to its ability to inhibit the mitochondrial electron transport chain and inhibit ATP production. NPEB's biological properties are well characterized. FTIR spectroscopy showed that this molecule has an amide functional group and is a small molecule with a molecular weight of 176.4 g/mol. This molecule was also found to be able to bind to mitochondria in animals.</p>Formula:C15H15NOPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:225.29 g/mol1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine
CAS:<p>1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine is an analytical standard and a drug product. It is a synthetic compound that has been shown to have pharmacological effects similar to those of the analgesic or opioid drugs. 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine can be used as an impurity standard for HPLC analyses as well as metabolic studies. This compound is also known to have potential interactions with other drugs.</p>Formula:C24H27NO3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:377.48 g/molPantoprazole sodium hydrate - Mixture of impurities D and F
CAS:<p>Pantoprazole sodium hydrate is a custom synthesis that is used as a drug product. The CAS number for this compound is 624742-53-6. This compound has the following impurities: D and F. Pantoprazole sodium hydrate has been shown to be metabolized in vitro by human liver microsomes to its metabolites, including the following: (1) pantoprazol acid, (2) 4-hydroxypantoprazol acid, (3) 4-hydroxyisoxazole acid, and (4) 5-(4-hydroxyphenyl)-2H-1,2-benzoxazin-3(4H)-one. The metabolite 4-hydroxypantoprazol acid has been found to be pharmacologically active in animal models of gastric ulceration and healing.</p>Formula:C17H17F2N3O4SPurity:Min. 95%Color and Shape:Off-white to yellow powder.Molecular weight:397.4 g/mol
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