Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10353 products of "Benzimidazole and Imidazole Derivatives"
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2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
CAS:Controlled Product<p>Applications An intermediate in the synthesis of Itraconazole.<br></p>Formula:C22H27N5O2Color and Shape:NeatMolecular weight:393.48Fenbendazole Sulfoxide-d3
CAS:Controlled Product<p>Applications A labelled metabolite of Fenbendazole (F246750).<br>References McKellar, Q., et al.: J. Vet. Pharmacol. Ther., 13, 223 (1990), De Ruyck, H., et al.: Food Control., 11, 165 (2000),<br></p>Formula:C152H3H10N3O3SColor and Shape:White To Off-WhiteMolecular weight:318.37Iso Letrozole
CAS:<p>Impurity Letrozole EP Impurity A; Letrozole USP Related Compound A<br>Applications Isoletrozole (Letrozole EP Impurity A) is an impurity of Letrozole (L330100). Letrozole impurity A as per USP.<br>References Fleming, F.F., et al.: J. Med. Chem., 53, 7902 (2010),<br></p>Formula:C17H11N5Color and Shape:NeatMolecular weight:285.30Glycopyrrolate Bromide-d3 (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Labelled analogue of Glycopyrrolate Bromide, a novel pharmaceutical compound based on PDE IV inhibitors. Glycopyrrolate Bromide is used in the treatment of respiratory complaints.<br>References Gomez, et al.: Br. J. Anaesth., 74, 549 (1995);<br></p>Formula:C19H25D3NO3·BrColor and Shape:NeatMolecular weight:401.35Temazepam-13C,d3
CAS:Controlled Product<p>Applications Temazepam-13C,d3 is labelled Temazepam (T017200) which is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Formula:C1513CH10D3ClN2O2Color and Shape:NeatMolecular weight:304.75Tebuconazole
CAS:<p>Applications Tebuconazole is an ergosterol biosynthesis inhibitor present in most pesticide formulations (1,2). Various uptake is observed in plants (3). Drinking water Contaminant Candidate List 3 - CCL 3 as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants. Useful in cannabis testing kits as a component of pesticide mixes (P698235).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Grimalt S. et al.: Anal Bioanal Chem. 2015 Apr;407(11):3083-912. Gent, D. et al.: Plant Dis. 2003 May:87(5) p591-5973. Wang, C. et al.: Pest. Biochem. Physiol. 2007 Jan:87(1) p1-8<br></p>Formula:C16H22ClN3OColor and Shape:White To Light YellowMolecular weight:307.82Oxcarbazepine
CAS:<p>Applications A metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989); Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001);<br></p>Formula:C15H12N2O2Color and Shape:Light YellowMolecular weight:252.27(S)-N-Methyl Pregabalin
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications The major metabolite of Pregabalin.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C9H19NO2Color and Shape:NeatMolecular weight:173.25(R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid
CAS:Controlled Product<p>Applications An impurity of the anti-convulsant (S)-Pregabalin (P704790).<br>References Lin, S. et al.: J. Liq. Chrom. Rel. Technol., 19, 2699 (1996); Sripathi, S. et al.: ARKIVOC, 10, 266 (2010);<br></p>Formula:C9H17NO3Color and Shape:White To Off-WhiteMolecular weight:187.24Lansoprazole Sulfone
CAS:<p>Impurity Lansoprazole USP Related Compound A<br>Applications A metabolite of Lansoprazole, as gastric pump inhibitor. Lansoprazole USP Related Compound A.<br>References De Morais, S., et al.: Mol. Pharmacol., 46, 594 (1994), Spencer, C., et al.: Drugs, 48, 404 (1994), Pearce, R., et al.: J. Pharmacol. Exp. Ther., 277, 805 (1996), Tassaneeyakul, W., et al.: Br. J. Clin. Pharmacol., 49, 139 (2000),<br></p>Formula:C16H14F3N3O3SColor and Shape:NeatMolecular weight:385.36Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone
CAS:Controlled Product<p>Applications Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Formula:C31H28N2OColor and Shape:NeatMolecular weight:444.573-(2,3-Dichlorobenzamido) Lamotrigine
CAS:<p>Impurity Lamotrigine EP Impurity F/ Lamotrigine Related Compound D<br>Stability Light Sensitive<br>Applications 3-(2,3-Dichlorobenzamido) Lamotrigine (Lamotrigine EP Impurity F) an impurity of the anticonvulsant Lamotrigine (L173250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Emami, J. et al.: J. Pharmac. Biomed. Anal., 40, 999 (2006); Srinivasulu, P. et al.: Chromatographia, 70, 271 (2009);<br></p>Formula:C16H9Cl4N5OColor and Shape:NeatMolecular weight:429.09(R)-Modafinil Carboxylate Methyl Ester
CAS:Controlled ProductFormula:C16H16O3SColor and Shape:NeatMolecular weight:288.365-(S-Methyl) Albendazole
CAS:<p>Impurity Albendazole EP Impurity F<br>Applications 5-(S-Methyl) Albendazole is a metabolite of Albendazole (A511610). Albendazole EP Impurity F<br>References Gyurik, R.J., et al.: Drug Metab. Dispos., 9, 503 (1981),<br></p>Formula:C10H11N3O2SColor and Shape:NeatMolecular weight:237.28Methyl 2-(1H-imidazol-1-yl)acetate
CAS:Formula:C6H8N2O2Purity:95.0%Color and Shape:SolidMolecular weight:140.142N-(2-Hydroxyethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide
CAS:<p>Applications N-(2-Hydroxyethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide is a photolysis product of Metronidazole (M338880), an antibiotic.<br>References Moore, Douglas E., et al.: Radiation Phy. and Chem., 36(4), 547-50 (1990)<br></p>Formula:C6H9N3O3Color and Shape:NeatMolecular weight:171.154TRAM-34
CAS:Controlled Product<p>Applications TRAM-34 blocks intermediate conductance calcium-activated potassium channel IKCa1 with a Kd of 20nM and exhibits exquisite selectivity for the channel. Clotrimazole impurity.<br>References Wulff, H., et al.: J. of Biological Chemistry, 276, 34, 32040 (2001)<br></p>Formula:C22H17ClN2Color and Shape:NeatMolecular weight:344.84Thiabendazole-d4 (Major)
CAS:Controlled ProductFormula:C10D4H3N3SColor and Shape:Off WhiteMolecular weight:205.27Oxazepam-d5
CAS:Controlled Product<p>Applications Labelled Oxazepam. Anxiolytic; muscle relaxant (skeletal); anticonvulsant; ligand for the GABAA receptor benzodiazepinemodulatory site.Controlled substance (depressant).<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Sisenwine, et al.: Arzneim. Forsch., 22, 682 (1972), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 3, 441 (1974), Greenblatt, D.J., et al.: Clin. Pharmacokinet., 6, 89 (1981),<br></p>Formula:C152H5H6ClN2O2Color and Shape:Off-WhiteMolecular weight:291.74
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