Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
At CymitQuimica, we offer high-purity benzimidazoles and imidazoles for research in medicinal chemistry, pharmacology, and biotechnology.
Found 10353 products of "Benzimidazole and Imidazole Derivatives"
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4-Hydroxy Midazolam
CAS:Controlled Product<p>Applications A metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Midazolam is also a positive allosteric modulator of the GABAA receptor.<br>References Ha, H., et al.: Ther. Drug Monit., 15, 338 (1993), Thummel, K., et al.: J. Pharmacol. Exp. Ther., 271, 557 (1994), Kim, R., et al.: Pharm. Res., 16, 408 (1999), Maurer, H., et al.: Anal. Bioanal. Chem., 381, 110 (2005), Smink, B., et al.: J. Anal. Toxicol., 30, 478 (2006), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3OColor and Shape:Off-WhiteMolecular weight:341.77cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-4-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate
CAS:<p>Impurity Itraconazole Impurity 16<br>Applications cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-4-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate (Itraconazole Impurity 16) is an impurity in the synthesis of Itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989);<br></p>Formula:C14H15Cl2N3O5SColor and Shape:NeatMolecular weight:408.257N-(2-Chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:287.755-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:329.4200134277344N-Methyl Pantoprazole(Mixture of 1 and 3 isomers)
CAS:<p>Impurity Pantoprazole EP Impurity D;<br>Applications N-Methyl Pantoprazole (Pantoprazole EP Impurity D) is an impurity of Omeprazole and Pantoprazole. Mixture of 1 and 3 isomers (mixture of impurity D and F).<br>References McClean, S., et al.: Anal. Chim. Acta, 292, 81 (1994), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997), Avgerinos, A., et al.: Eur. J. Drug Metab. Pharmacokinet., 23, 329 (1998), Wahbi, A., et al.: J. Pharm. Biomed. Anal., 30, 1133 (2002),<br></p>Formula:C17H17F2N3O4SColor and Shape:Light RedMolecular weight:397.40Hydroxy Itraconazole-d8
CAS:Controlled Product<p>Applications An isotopically Labelled metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. It is a COVID19-related research product.<br>References Saag, M., et al.: Antimicrob. Agents Chemother., 32, 1 (1988), Haria, M., et al.: Drugs, 51, 585 (1996), Kousoulos, C., et al.: Anal. Bioanal. Chem., 384,199 (2006),<br></p>Formula:C35D8H30Cl2N8O5Color and Shape:NeatMolecular weight:729.68Lansoprazole
CAS:<p>Applications Used as a gastric proton pump inhibitor. An antiulcerative. May limit the severity of tuberculosis (see Chem. and Eng. News. p. 28 July 20 (2018)).<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006), Chem. and Eng. News. p. 28 July 20 (2018)<br></p>Formula:C16H14F3N3O2SColor and Shape:White To Light BeigeMolecular weight:369.36Ronidazole
CAS:<p>Applications Antimicrobial.<br>References Yamada, R., et al.: Biosci. Biotechnol. Biochem., 70, 54 (2006), Mohamed, R., et al.: J. Agric. Food Chem., 56, 3500 (2008), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009),<br></p>Formula:C6H8N4O4Color and Shape:Light YellowMolecular weight:200.155-Nitro-1H-imidazole-1-ethanol
CAS:Controlled Product<p>Applications 5-Nitro-1H-imidazole-1-ethanol (cas# 5006-68-8) is a compound useful in organic synthesis.<br></p>Formula:C5H7N3O3Color and Shape:NeatMolecular weight:157.13Miconazole Impurity B
CAS:Controlled Product<p>Applications Miconazole Impurity B, is the impurity of Miconazole (M342500), which is an imidazole antifungal agent, that is applied topically to the skin or to mucus membranes for the treatment of fungal infections.<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H15Cl3N2OColor and Shape:NeatMolecular weight:381.686-Desfluoro Rufinamide
CAS:Controlled Product<p>Applications 6-Desfluoro Rufinamide is an impurity in the synthesis of Rufinamide (R701550), an antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H9FN4OColor and Shape:NeatMolecular weight:220.20Ronidazole-d3
CAS:Controlled Product<p>Applications Labelled Ronidazole (R640200). Antimicrobial.<br>References Yamada, R., et al.: Biosci. Biotechnol. Biochem., 70, 54 (2006), Mohamed, R., et al.: J. Agric. Food Chem., 56, 3500 (2008), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009),<br></p>Formula:C62H3H5N4O4Color and Shape:Off-WhiteMolecular weight:203.17Albendazole-d3 (Methoxy-d3)
CAS:Controlled Product<p>Applications Albendazole-d3 (methoxy-d3) is deuterium labelled Albendazole (A511610), which is an anthelmintic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhao, Y., et al.: Org. Biomol. Chem., 6, 4509 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C10H12N3SColor and Shape:Off White SolidMolecular weight:268.354-Nitro-1H-imidazole-1-ethanol
CAS:Controlled Product<p>Applications 4-Nitro-1H-imidazole-1-ethanol<br></p>Formula:C5H7N3O3Color and Shape:WhiteMolecular weight:157.132-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
CAS:Controlled Product<p>Applications 2-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole is a drug impurity of Lansoprazole, which is a proton pump inhibitor and used to treat stomach and intestinal ulcers.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000); Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001); Barradell, L.B., et al.: Drugs, 44, 225 (1992); Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002); Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006)<br></p>Formula:C14H12N4O3SColor and Shape:NeatMolecular weight:316.34Des [3-(1-Dimethylamino)ethyl] 3-Acetyl Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity C; USP Related Compound D<br>Applications Des [3-(1-dimethylamino)ethyl] 3-acetyl Rivastigmine (Rivastigmine EP Impurity C) is a derivative of Rivastigmine (Tartrate: R541000), and acetylcholinesterase inhibitor that is commonly used to treat dementia associated with Parkinson’s disease and Alzheimer’s disease.<br>References Emre, M., et al.: New. Engl. J. Med., 351, 2509 (2004); Polinsky, R.: Clin. Ther., 20, 634 (1998); Wilkinson, D., et al.: Int. J. Clin. Pract., 56, 441 (2001)<br></p>Formula:C12H15NO3Color and Shape:Off-WhiteMolecular weight:221.25Modafinil Carboxylate
CAS:Controlled ProductFormula:C15H14O3SColor and Shape:NeatMolecular weight:274.33Albendazole Sulfoxide
CAS:<p>Impurity Albendazole EP Impurity B<br>Applications Albendazole Sulfoxide (Albendazole EP Impurity B) is a metabolite of Albendazole, an anthelmintic.<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol Lett., 6, 2: 51 (1996)<br></p>Formula:C12H15N3O3SColor and Shape:White To BrownMolecular weight:281.33
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