Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65495 products of "Quinazoline and Quinoline Derivatives"
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Desethyl Terbuthylazine-d9
CAS:Controlled ProductFormula:C72H9H3ClN5Color and Shape:Off White SolidMolecular weight:210.71Macitentan-d4
CAS:Controlled Product<p>Applications Macitentan-d4 is an isotopic form of Macitentan (M105005). Macitentan, is an orally active endothelin receptor antagonist used for pulmonary arterial hypertension.<br>References Emoto, N. Ensho to Men'eki, 20, 487 (2012);<br></p>Formula:C19H16D4Br2N6O4SColor and Shape:NeatMolecular weight:592.3Nifuratel
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Nifuratel is a drug used as an antibacterial, antifungal, antiprotozoal (Trichomonas). Nifuratel appears to have a broad antibacterial spectrum of action and is effective against Chlamydia trachomatis and Mycoplasma spp. as well as fungal infections from Candida spp.<br>References Nam, H., et al.: J. Microbiol., 45, 515 (2007), Costerton, W., et al.: J. Clin. Invest., 112, 1466 (2003), Ferris, M., et al.: J. Clin. Microbiol., 42, 5892 (2004),<br></p>Formula:C10H11N3O5SColor and Shape:Yellow To Dark YellowMolecular weight:285.28Flumequine
CAS:Controlled Product<p>Applications Fluorinated quinolone antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Stilwell, G., et al.: Antimicrob. Agents Chemother., 7, 483 (1975), Rohlfing, S.R., et al.: J. Antimicrob. Chemother., 3, 615 (1977),<br></p>Formula:C14H12FNO3Color and Shape:White Crystalline PowderMolecular weight:261.252-(((5-((Dimethylamino)methyl)furan-2-yl)methyl)thio)ethanamine Fumarate (2:1)
CAS:Controlled Product<p>Impurity USP Ranitidine Related Compound A<br>Applications 2-(((5-((Dimethylamino)methyl)furan-2-yl)methyl)thio)ethanamine (E)-2-Butenedioate is an impurity of Ranitidine (R120000), a histamine H2-receptor antagonist which inhibits gastric acid secretion. Antiulcerative.<br>References Bradshaw, J., et al.: Brit. J. Pharmacol., 66, 464 (1979), Berstad, A., et al.: Scand. J. Gastroenterol, 15, 637 (1980), Hohnjec, M., et al.: Anal. Profiles Drug Subs., 15, 533 (1986),<br></p>Formula:C10H18N2OS·C4H4O4Color and Shape:WhiteMolecular weight:544.7276Paliperidone Z-Oxime
CAS:Controlled Product<p>Applications Paliperidone Z-oxime is an impurity of Paliperidone (P141000), a known orally active antipsychotic agent.<br>References Rao, J., et al.: Pharmacia Lettre, 3, 240 (2011);<br></p>Formula:C23H28F2N4O3Color and Shape:NeatMolecular weight:446.492-[4-[2-(1-Piperidinyl)ethoxy]benzoyl]benzoic Acid
CAS:<p>Applications 2-[4-[2-(1-Piperidinyl)ethoxy]benzoyl]benzoic Acid is a research reagent with antispasmodic<br>References Bal-Tembe, S., et al.: Bioorg. Med. Chem., 5, 1381(1997);Punekar, N., et al.: Biotech. App. Biochem, 14, 378 (1991);<br></p>Formula:C21H23NO4Color and Shape:NeatMolecular weight:353.41ent-Rivaroxaban
CAS:<p>Applications ent-Rivaroxaban is the R-isomer of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C19H18ClN3O5SColor and Shape:White To Off-WhiteMolecular weight:435.881,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester
CAS:<p>Impurity Nicardipine USP Related Compound A<br>Applications 1,4-Dihydropyridine derivative used in the prevention and therapy of atherosclerotic degradation of arterial walls. Nicardipine USP Related Compound A.<br>References Henry, P.D., et al.: Clin. Invest. Med., 10, 601 (1987), Weinstein, D.B., et al.: Am. J. Med., 86, 27 (1989), Gaviraghi, G., et al.: Pharmacol. Res., 31, 251 (1995),<br></p>Formula:C16H16N2O6Color and Shape:Light YellowMolecular weight:332.31Riluzole-13C,15N2
CAS:Controlled ProductFormula:C713CH5F315N2OSColor and Shape:Light Beige To Light YellowMolecular weight:237.18ent-Ezetimibe
CAS:<p>Applications An enantiomeric impurity of Ezetimibe (E975005).<br></p>Formula:C24H21F2NO3Color and Shape:White To Off-WhiteMolecular weight:409.43Medetomidine-13C,d3 Hydrochloride
CAS:Controlled Product<p>Applications Labelled α2-adrenergic agonist. Sedative; analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>Formula:CC122H3H13N2·ClHColor and Shape:White To Light YellowMolecular weight:240.75N-Carbamoyl Linagliptin
CAS:Controlled Product<p>Applications N-Carbamoyl Linagliptin is a derivative of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Formula:C26H29N9O3Color and Shape:NeatMolecular weight:515.57Diazoxide-d3
CAS:Controlled Product<p>Applications Diazoxide-d3 is the labeled analogue of Diazoxide (D417305), which reduces status epilepticus neuron damage in diabetes.<br>References Baba, A., et al.: J. Neurosci., 23, 7737 (2003); Bancila, V., et al.: J. Neurochem., 90, 1243 (2004); Bancila, V., et al.: J. Biol. Chem., 280, 8793 (2005)<br></p>Formula:C8H4D3ClN2O2SColor and Shape:NeatMolecular weight:233.69Dipropylaminopretadalafil
Controlled Product<p>Applications Dipropylaminopretadalafil is a derivative of Chloropretadalafil (M330125), an intermediate in the synthesis of Tadalafil, which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003)<br></p>Formula:C28H33N3O5Color and Shape:Off White SolidMolecular weight:491.58N-Methyl Amisulpride
CAS:<p>Impurity Amisulpride EP Impurity H<br>Applications N-Methyl Amisulpride is an impurity of Amisulpride (A633250). Amisulpride EP Impurity H Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985), Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997),<br></p>Formula:C18H29N3O4SColor and Shape:NeatMolecular weight:383.51Eltrombopag-13C4
CAS:Controlled ProductFormula:C2113C4H22N4O4Color and Shape:Light Yellow To Dark OrangeMolecular weight:446.44Flumequine-13C3
CAS:Controlled Product<p>Applications Fluorinated quinolone antibacterial.<br>References Stilwell, G., et al.: Antimicrob. Agents Chemother., 7, 483 (1975), Rohlfing, S.R., et al.: J. Antimicrob. Chemother., 3, 615 (1977),<br></p>Formula:C3C11H12FNO3Color and Shape:Off-White To BeigeMolecular weight:264.234-Hydroxy Omeprazole Sulfone
CAS:Controlled Product<p>Applications The major degradation product of 4-Hydroxy Omeprazole (H948860).<br></p>Formula:C16H17N3O4SColor and Shape:White SolidMolecular weight:347.39Thiamethoxam
CAS:<p>Applications A neonicotinoid insecticide. Reports show that when exposed to neonicotinid pesticides honeybees have probelms returnign home after foraging and bumblebee colonies grow poorly and produce fewer queens. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Oliver, J., et al.: J. Environ. Horticult., 28, 135 (2010), Ghosh, A., et al.: J. Entomol. Res., 34, 35 (2010), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:C8H10ClN5O3SColor and Shape:BeigeMolecular weight:291.71Clidinium Bromide
CAS:Controlled Product<p>Applications An anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Formula:C22H26NO3·BrColor and Shape:White SolidMolecular weight:432.352-Hydroxy Imipramine
CAS:Controlled Product<p>Applications A metabolite of Imipramine.<br>References De Jongh, G.D., et al.: Drug Metab. Dispos., 2, 48 (1981), Suckow, R.F., et al.: J. Pharm. Sci., 73, 1745 (1984), Fraser, A.D., et al.: J. Anal. Toxicol., 11,168 (1987),<br></p>Formula:C19H24N2OColor and Shape:Yellowish SolidMolecular weight:296.41(R)-Etiracetam Acid
CAS:Controlled Product<p>Applications Levetiracetam Acid can be used as reactant/reagent in synthesis, Aβ42/tau aggregation, acetylcholinesterase/butyrylcholinesterase inhibitory activities, acute toxicity, and docking studies of levetiracetam-huprine/tacrine hybrids as anti-Alzheimer's agents.<br>References Sola, I., et al.: J Med Chem, 58, 6018 (2015)<br></p>Formula:C8H13NO3Color and Shape:Off-WhiteMolecular weight:171.193-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide
CAS:Controlled Product<p>Impurity Famotidine EP Impurity D<br>Stability Hygroscopic<br>Applications 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide is an impurity in the synthesis of Famotidine (F102250) histamine H2-receptor antagonist. Antiulcerative.<br>References Takeda, M., et al.: Arzneim.-Forsch., 32, 734 (1982), Miwa, M., et al.: J. Clin. Pharmacol. Ther. Toxicol., 22, 214 (1984), Takabatke, T., et al.: Eur. J. Clin. Pharmacol., 28, 327 (1985),<br></p>Formula:C8H13N5OS2Color and Shape:NeatMolecular weight:259.354,5-Desisopropylidene Topiramate
CAS:Controlled Product<p>Impurity Topiramate Impurity B<br>Applications A metabolite of Topiramate.<br>References Maryanoff, B., et al.: J. Med. Chem., 30, 880 (1987), Shank, R., et al.: Epilepsia, 35, 450 (1994), Streeter, A., et al.: Drug Metab. Disp., 23, 90 (1995),<br></p>Formula:C9H17NO8SColor and Shape:WhiteMolecular weight:299.30Pentoxifylline
CAS:Controlled ProductFormula:C13H18N4O3Color and Shape:White To Off-WhiteMolecular weight:278.31Cyanuric Acid (1 mg/10 mL in 84:16% ACN:H2O)
CAS:Controlled ProductFormula:C3H3N3O3Color and Shape:Single SolutionMolecular weight:129.07Trityl Chloride
CAS:Controlled Product<p>Applications Trityl Chloride is an alkyl halide commonly used in organic synthesis to introduce the trityl protecting group. Trityl Chloride is used in the preparation of S-trityl-L-cysteine (STLC), a tight-binding inhibitor of Eg5 that prevents mitotic progression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References DeBonis, S. et al.: J. Med. Chem., 51, 1115 (2008); Chadwick, D.J. et al.: J. Chem. Soc. Perk. Trans. Org. Bio-Org. Chem., 1, 102 (1983);<br></p>Formula:C19H15ClColor and Shape:NeatMolecular weight:278.78Saquinavir
CAS:Controlled Product<p>Applications Saquinavir (CAS# 127779-20-8) is a useful research chemical compound.<br></p>Formula:C38H50N6O5Color and Shape:White To Off-WhiteMolecular weight:670.84(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
CAS:Controlled Product<p>Applications Intermediate in the preparation of Efavirenz (E425000) impurity.<br></p>Formula:C13H11ClF3NOColor and Shape:NeatMolecular weight:289.682-Chloro-N-(3-chloro-2-methylphenyl)nicotinamide
CAS:<p>Applications An impurity of Clonixine (L488530). Clonixine is a nonsteroidal anti-inflammatory agent used as an analgesic.<br>References Esteve, M.H., et al.: J. High Res. Chromatogr., 13, 445 (1990),<br></p>Formula:C13H10Cl2N2OColor and Shape:Off-WhiteMolecular weight:281.143-Acetyl-2(1H)-pyridinone
CAS:Formula:C7H7NO2Purity:98%Color and Shape:Solid, CrystallineMolecular weight:137.138rac Penbutolol
CAS:<p>Applications A β-adrenoceptor antagonist. Antihypertensive.<br>References Armstrong, D., et al.: Anal. Chem., 66, 1473 (1994), Kato, M., et al.: J. Pharm. Biomed. Anal., 30, 1845 (2003),<br></p>Formula:C18H29NO2Color and Shape:Off-WhiteMolecular weight:291.43(R)-Bicalutamide
CAS:Controlled Product<p>Applications (R)-Enantiomer of Bicalutamide. Used as an antiandrogen, antineoplastic (hormonal).<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),<br></p>Formula:C18H14F4N2O4SColor and Shape:WhiteMolecular weight:430.374-Hydroxy Nisoldipine
CAS:Controlled Product<p>Applications A metabolite of Nisoldipine<br></p>Formula:C20H24N2O7Color and Shape:NeatMolecular weight:404.41Demethyl Chlorpromazine Hydrochloride
CAS:Controlled Product<p>Impurity Chlorpromazine EP Impurity D<br>Applications A metabolite of Chlorpromazine (C424750).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Neuhoff, E., et al.: Archiv. der Pharmazie, 288, 400 (1955), Tomita, M., et al.: Chem. Pharm. Bull., 16, 688 (1968),<br></p>Formula:C16H17ClN2S·ClHColor and Shape:WhiteMolecular weight:341.304,6-Dimethyl-2-hydroxypyrimidine
CAS:Controlled Product<p>Applications 4,6-Dimethyl-2-hydroxypyrimidine is a component of Nicarbazine (N394530), a coccidiostat, which is an antiprotozoal agent that acts upon Coccidia parasites.<br>References Ksenija Sinigoj, G., et al.: Slovenski Kemijski Dnevi, (2012); Kyung-Woo, L., et al.: Han'guk Kagum Hakhoechi, 39, 17 (2012);<br></p>Formula:C6H8N2OColor and Shape:NeatMolecular weight:124.145-(4-Nitrophenyl)-2-furaldehyde Azine
CAS:Controlled ProductFormula:C22H14N4O6Color and Shape:NeatMolecular weight:430.37Reserpic Acid Methyl Ester
CAS:Controlled Product<p>Applications Reserpine (R144600) derivative, an alkaloid found in Rauwolfia.<br>References Itoh, A. et al.: J. Nat. Prod. 68, 848 (2005)<br></p>Formula:C23H30N2O5Color and Shape:NeatMolecular weight:414.49Tolcapone-d4
CAS:Controlled Product<p>Applications Orally active inhibitor of central and peripheral catechol-O-methyltransferase (COMT). Antiparkinsonian.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dingemanse, J., et al.: Clin. Pharmacol. Ther., 57, 508 (1995), Keating, K.A., Drugs, 19, 165 (2005),<br></p>Formula:C14H7D4NO5Color and Shape:NeatMolecular weight:277.27(±)-Mianserin-d3 Hydrochloride (methyl-d3)
CAS:Controlled Product<p>Applications (±)-Mianserin-d3 HCl (methyl-d3) (CAS# 1219804-97-3) is a useful isotopically labeled research compound.<br></p>Formula:C18D3H17N2·ClHColor and Shape:NeatMolecular weight:303.8442Loxoprofen-d3
CAS:Controlled Product<p>Applications Loxoprofen-d3, is the labeled analogue of Loxoprofen (L472905), which is non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation.<br>References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);<br></p>Formula:C15H15D3O3Color and Shape:NeatMolecular weight:249.32(E)-Chlorprothixene-d6 Hydrochloride
CAS:Controlled Product<p>Applications Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 63 (1973), Bagli, M., et al.: Arzneim.-Forsch., 46, 247 (1996),<br></p>Formula:C18H13D6Cl2NSColor and Shape:NeatMolecular weight:358.36S-(2-Guanidino-4-thiazolyl)methylisothiourea Dihydrochloride
CAS:Formula:C6H10N6S2·2ClHColor and Shape:NeatMolecular weight:303.236(R)-N-Desacryloyl N-Propionyl Ibrutinib
CAS:<p>Applications (R)-N-Desacryloyl N-Propionyl Ibrutinib is an inhibitor for bruton’s tyrosine kinase.<br>References Pan, Z., et al.: ChemMedChem (2007), 2(1), 58-61<br></p>Formula:C25H26N6O2Color and Shape:NeatMolecular weight:442.51Descarboxyl Levofloxacin
CAS:Controlled Product<p>Impurity Levofloxacin Descarboxy Impurity<br>Applications A degradation product of Levofloxacin (L360000).<br>References Wong, F., et al.: J. Pharm. Biomed. Anal., 15, 765 (1997), Singh, G., et al.: Pharmazie, 43, 134 (1988), Radi, A., et al.: Talanta, 58, 319 (2002),<br></p>Formula:C17H20FN3O2Color and Shape:Off-White To Light YellowMolecular weight:317.36Levetiracetam-d3 (contains d0)
CAS:Controlled Product<p>Applications The labelled (S)-enantiomer of Etiracetam (E932970) and the ethyl analog of Piracetam (P500800). Used as an anticonvulsant.<br>References Gower, A.J., et al.: Eur. J. Pharmacol., 222, 193 (1992), Kasteleijn-Noist Trenite, D.G.A., et al.: Epilepsy Res., 25, 225 (1996), Patsalos, P.N., et al.: Pharmacol. Ther., 85, 77 (2000),<br></p>Formula:C8H11D3N2O2Color and Shape:NeatMolecular weight:170.21N-Nitrosoephedrine-D3
CAS:Controlled ProductFormula:C10D3H11N2O2Color and Shape:White To Off-WhiteMolecular weight:197.249Valsartan-d3
CAS:Controlled ProductFormula:C24H26D3N5O3Color and Shape:Off-WhiteMolecular weight:438.5423-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol
CAS:Controlled Product<p>Impurity Metoprolol EP Impurity D<br>Applications 3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol (Metoprolol EP Impurity D) is a new byproduct detected in Metoprolol tartrate. Metoprolol (M338790) impurity.<br>References Erickson, M., et al.: J. Pharmac. Biomed. Anal., 13, 567 (1995),<br></p>Formula:C12H18O4Color and Shape:WhiteMolecular weight:226.27Ondansetron
CAS:Controlled Product<p>Applications Ondansetron is a specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988); Faris, P..L., et al.: Lances, 355, 792 (2000)<br></p>Formula:C18H19N3OColor and Shape:White To Light BeigeMolecular weight:293.36cis-(Z)-Flupentixol Dihydrochloride
CAS:Controlled Product<p>Applications Neuroleptic agent related structurally to thiothixene. Antipsychotic; neuroleptic agent; dopamine receptor antagonist.<br>References Nielsen, et al.: Acta Pharmacol. Toxicol., 32, 363 (1973), Post, M.L., et al.: Nature, 256, 342 (1975), Peuch, et al.: Neuropharmacology, 20, 1279 (1981),<br></p>Formula:C23H27Cl2F3N2OSColor and Shape:NeatMolecular weight:507.44PTC-124
CAS:Controlled Product<p>Applications PTC-124 is a nonaminoglycoside that has been reported to induce ribosomes to read through premature nonsense stop signals on mRNA, allowing the production of full-length functional proteins,<br>References Yu, H. et al.: Int. J. Mol. Med., 33, 729 (2014); Aditya, S. et al.: J. Biomed. Pharm. Res., 2, 21 (2013);<br></p>Formula:C15H9FN2O3Color and Shape:White To Off-WhiteMolecular weight:284.248-Bromo-3-methyl-7-(2-butynyl)-xanthine
CAS:Controlled ProductFormula:C10H9BrN4O2Color and Shape:NeatMolecular weight:297.108Afatinib Dimaleate
CAS:Controlled Product<p>Applications Afatinib Dimaleate is a salt of Afatinib {BIBW 2992) (B377000), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. An anilino-quinazoline that irreversibly inhibits EGFR and HER2 kinase activity.<br>References D, Li. et al.: Oncogene., 27, 4702 (2008); Wang, X. et al.: Cancer Res., 74, 4431 (2014);<br></p>Formula:C24H25ClFN5O3·2C4H4O4Color and Shape:NeatMolecular weight:718.08Bupivacaine
CAS:<p>Applications Bupivacaine is a sodium channel blocker, local anesthetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wilson, T.D., et al.: Anal. Profiles Drug Subs., 19, 59 (1990), McClellan, K.J., et al.: Drugs, 56, 355 (1998),<br></p>Formula:C18H28N2OColor and Shape:NeatMolecular weight:288.435-(p-Methylphenyl)-5-phenylhydantoin
CAS:<p>Applications An antibody agent.<br>References Rowell, F. J., et al.: Immunochemistry, 13, 891 (1976),<br></p>Formula:C16H14N2O2Color and Shape:NeatMolecular weight:266.29Desthiazolylmethyl Ritonavir
CAS:Controlled Product<p>Impurity Ritonavir EP Impurity L<br>Applications Desthiazolylmethyl Ritonavir (Ritonavir EP Impurity L) is an analogue of the selective HIV protease inhibitor Ritonavir (R535000). It is a COVID19-related research product.<br>References Brittain, H., et al.: Pharm. Res., 8, 963 (1991), Sham, H., et al.: J. Med. Chem., 39, 392 (1996), Phadnis, N., et al.: J. Pharm. Sci.,86, 1256 (1997), Bauer, J., et al.: Pharma. Res., 18, 859 (2001),<br></p>Formula:C33H43N5O4SColor and Shape:White To Off-WhiteMolecular weight:605.79Pyraclostrobin
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Pyraclostrobin is a fungicide for use in seed grass and food crops. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gyldenkaerne, S., et al.: Pestic Sci., 55, 1210 (1999), Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007),<br></p>Formula:C19H18ClN3O4Color and Shape:YellowMolecular weight:387.82Celecoxib Carboxylic Acid Acyl-β-D-glucuronide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Celecoxib Carboxylic Acid Acyl-β-D-glucuronide is a glucuronide metabolite of Celecoxib (C251000), a Cox-2 inhibitor.<br>References Penning, T., et al.: J. Med. Chem., 40, 1347 (1997), Barta, T., et al.: Bioorg. Med. Chem. Lett., 8, 3443 (1998), Paulson, S., et al.: Drug Metab. Dispos., 28, 514 (2000),<br></p>Formula:C23H20F3N3O10SPurity:>80%Color and Shape:NeatMolecular weight:587.48Teneligliptin Hydrobromide (2:5)
CAS:Controlled Product<p>Applications Teneligliptin Hydrobromide (2:5) is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion, and has a half-life of 24.2 hours in the human body.<br>References Goda, M. & Kadowaki, T.: Drugs Today, 49, 615 (2013); Kishimoto, M.: Diabetes Metab. Syndr. Obes., 6, 187 (2012)<br></p>Formula:C22H32·5Br2·5N6OSColor and Shape:NeatMolecular weight:628.86(R)-(-)-Chlorpheniramine Maleate
CAS:Formula:C16H19ClN2•C4H4O4Color and Shape:NeatMolecular weight:274.7911607Hydroxy Dimetridazole-d3
CAS:Controlled Product<p>Applications A labelled metabolite of Dimetridazole (D479660).<br>References Voogd, C., et al.: Mutat. Res., 86, 243 (1981), Polzer, J., et al.: Anal. Chim. Acta., 529, 299 (2005), Mohamed, R., et al.: J. Agric .Food Chem., 56, 3500 (2008),<br></p>Formula:C52H3H4N3O3Color and Shape:BeigeMolecular weight:160.15Ofloxacin N-Oxide Acetic Acid Salt (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications A metabolite of Ofloxacin.<br>References Uematsu, T., et al.: Eur. J. Clin. Pharmacol., 40, 581 (1991), Uematsu, T., et al.: Ther. Drug Monit., 17, 101 (1995), Ballesteros, O., et al.: J. Pharm. Biomed. Anal., 30, 1103 (2002), Kitade, T., et al.: Chem. Pharm. Bull., 51, 53 (2003),<br></p>Formula:C18H20FN3O5·ClHColor and Shape:NeatMolecular weight:437.419Silodosin
CAS:<p>Applications Silodosin is an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertrophy.<br>References (1) Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995) (2) Murata, S., et al.: J. Urol., 164, 578 (2000)<br></p>Formula:C25H32F3N3O4Color and Shape:NeatMolecular weight:495.53Noradrenalone Hydrochloride
CAS:Controlled Product<p>Applications Noradrenalone Hydrochloride is an intermediate of Norepinephrine (N674500), an antagonist of dibutyryl cyclic AMP in the regulation of narcosis. Norepinephrine modulates human dendritic cell activation by altering cytokine release.<br>References Strobel, G., et. al.: Eur. J. Biochem., 176, 397 (1988); Piguet, P., et al.: J. Exp. Med., 173, 673 (1991); Hosoi, J., et al.: Nature, 363, 159 (1993); Elenkov, I., et al.: Pharmacol. Rev., 52, 595 (2000); Kaplan, D., et al.: Immunity, 23, 611 (2005)<br></p>Formula:C8H10ClNO3Color and Shape:Dark Yellow To Dark BrownMolecular weight:203.625-Ethyl-demethyl Lercanidipine
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications 5-Ethyl-demethyl Lercanidipine is an impurity of Lercanidipine (L179000), which is a dihydropyridine calcium channel blocker.<br>References Bianchi, G., et al.: Pharmacol. Res., 21, 193 (1989); Rimoldi, E., et al.: Acta Therap., 200, 23 (1994); Argekar, A., et al.: J. Pharm. Biomed. Anal., 21, 1137 (2000);<br></p>Formula:C37H43N3O6Color and Shape:NeatMolecular weight:625.75Ethionamide-d3
CAS:Controlled Product<p>Applications Ethionamide-d3 is the isotope labelled analogue of Ethionamide (E890420), a antibacterial (tuberculostatic) agent.<br>References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),<br></p>Formula:C8H7D3N2SColor and Shape:NeatMolecular weight:169.263-Hydroxy-2-pyrone
CAS:Controlled Product<p>Applications 3-Hydroxy-2-pyrone<br></p>Formula:C5H4O3Color and Shape:NeatMolecular weight:112.08N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Lisinopryl impurity.<br>References Goa, K.L., et al.: Drugs, 52, 564 (1996), Cao, X.J., et al.: J. Pharm. Biomed. Anal., 39, 39 (2005),<br></p>Formula:C16H24N2O4Color and Shape:White To Light BeigeMolecular weight:308.37Siponimod
CAS:Controlled Product<p>Applications Siponimod is a functional sphingosine -1 phosphate (SIP) antagonist used in the treatment of multiple sclerosis and other central nervous system-related diseases in human subjects. .<br>References Pelz, A., et al.: Eur. J. Immunol., 48, 498 (2018); O'Sullivan, S., et al.: Neuropharmacology, 113, 597 (2017)<br></p>Formula:C29H35F3N2O3Color and Shape:Light YellowMolecular weight:516.6Dibenzazepine-10,11-dione
CAS:Controlled Product<p>Applications Dibenzazepine-10,11-dione is an impurity of Oxcarbazepine (O869250). Dibenzazepine-10,11-dione is used as a reagent in the preparation of bifunctional dipolar electroluminescent template for optoelectronic applications.<br>References Chen, C.-T. et al.: Chem. Comm., 31, 3980 (2005); Heckendorn, R. et al.: Helv, Chim. Acta, 70, 1955 (1987);<br></p>Formula:C14H9NO2Color and Shape:NeatMolecular weight:223.23Levosimendan Triazene Impurity
CAS:<p>Stability Light Sensitive<br>Applications Levosimendan Triazene is an impurity of Levosimendan (L378000); a positive inotropic agent with vasodilating activity. Also cardiotonic.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)<br></p>Formula:C22H23N7O2Color and Shape:NeatMolecular weight:417.462-[3,5-Dichloro-4-(4-chlorobenzoyl)phenyl]-1,2,4-triazine-3,5(2H,4H)-dione
CAS:Controlled Product<p>Applications An anticoccidal triazine used for the treatment of coccidiosis in chickens. An impurity of Diclazuril (D436200).<br>References McFarland, J. et al.: J. Med. Chem., 35, 2543 (1992);<br></p>Formula:C16H8Cl3N3O3Color and Shape:NeatMolecular weight:396.61Praziquantel
CAS:<p>Applications Anthelmintic, effective against flatworms.<br>References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 (2010), Wang, W., et al.: Parasitol., 137, 1905 (2010),<br></p>Formula:C19H24N2O2Color and Shape:White To Off-WhiteMolecular weight:312.41Olanzapine Pamoate Hydrate
CAS:Controlled Product<p>Applications A new Olanzapine pamoate formulation of a second-generation antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Davis, J., et al.: Arch. Gen. Psychiatry, 60, 553 (2003), Kahn, R., et al.: Lancet, 371, 1085 (2008), Lauriello, J., et al.: J. Clin. Psychiatry, 69, 790 (2008),<br></p>Formula:C23H16O6·C17H20N4S·H2OColor and Shape:NeatMolecular weight:718.82(2-Piperidin-1-ylpyridin-4-yl)methylamine
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:191.2779998779297Hydrodolasetron
CAS:Controlled Product<p>Applications Hydrodolasetron, is the reduced form of Dolasetron (D528500), a specific serotonin (5HT3) receptor antagonist. Antiemetic.<br>References Boeijinga, P.H., et al.: Eur. J. Pharmacol., 219, 9 (1992), Miller, R.C., et al., Drug Dev. Res., 28, 87 (1993), Fauser, A.A., et al.: Eur. J. Cancer, 32, 1523 (1996), Graczyk, S.G., et al.: Anesth. Analg., 84, 325 (1997),<br></p>Formula:C19H22N2O3Color and Shape:White To Off-WhiteMolecular weight:326.39Moroxydine Hydrochloride
CAS:Controlled Product<p>Applications Moroxydine is an antiviral used against a number of RNA and DNA viruses.<br>References Gastillo-Garit, J.A.. et al.: Europ. J. Med. Chem., 46, 3324 (2011); Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005);<br></p>Formula:C6H13N5O·ClHColor and Shape:White To Off-WhiteMolecular weight:207.66(S)-Naproxen Acyl-β-D-glucuronide
CAS:<p>Applications A metabolite of Naproxen.<br>References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Jin, C., et al.: J. Pharmacol. Exp. Ther., 264, 475 (1993),King, C., et al.: Toxicol. Sci., 61, 49 (2001), Aresta, A., et al.: J. Pharm. Biomed. Anal., 39, 643 (2005),<br></p>Formula:C20H22O9Color and Shape:NeatMolecular weight:406.38Bis-[Des(5-Chloro-2-carboxythienyl)] Rivaroxaban Phthalamide
CAS:Controlled ProductFormula:C36H36N6O10Color and Shape:NeatMolecular weight:712.71Sitagliptin-d4 Phosphate
CAS:Controlled Product<p>Applications A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.<br>References Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006).<br></p>Formula:C162H4H11F6N5O·H3O4PColor and Shape:Off-WhiteMolecular weight:509.33Ketoconazole-d8
CAS:Controlled Product<p>Applications Deuterated Ketoconazole, an inhibitor of cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)<br></p>Formula:C26H20D8Cl2N4O4Color and Shape:White To BeigeMolecular weight:539.48Amisulpride-d5 N-Oxide
CAS:Controlled Product<p>Applications Labelled Amisulpride N-Oxide (A633265). Amisulpride N-Oxide is an impurity of Amisulpride (A633250). Amisulpride N-Oxide was identified as a photodegradation product of Amisulpride.<br>References Moulin, A., et al.: Eur. J. Drug Metab. Pharmcokinet., 3, 507 (1991), Chatterjee, B., et al.: J. Biotechnol., 3, 235 (2008), Breier, A., et al.: J. Pharm. Biomed. Anal., 46, 250 (2008),<br></p>Formula:C17H22D5N3O5SColor and Shape:WhiteMolecular weight:390.511-(3,4-Dichlorophenyl)piperazine
CAS:Controlled ProductFormula:C10H12Cl2N2Color and Shape:NeatMolecular weight:231.127-Hydroxy Quetiapine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.<br>References Newton, D., et al.: Drug Metab. Dispos., 23, 154 (1995), Tanaka, E., et al.: J. Clin. Pharm. Ther., 24, 7 (1999)<br></p>Formula:C21H25N3O3SColor and Shape:WhiteMolecular weight:399.515-Methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile
CAS:Controlled Product<p>Impurity Olanzapine EP Impurity A/ Olanzapene USP Related Compound A<br>Applications 5-Methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile (Olanzapine EP Impurity A) is an impurity of Olanzapine (O253750).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anon., et al.: Fed. Regist., 65, 83041 (2000), Yu, L., et al.: J. Phys. Chem., 106, 544 (2002),<br></p>Formula:C12H9N3O2SColor and Shape:NeatMolecular weight:259.28
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