Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65495 products of "Quinazoline and Quinoline Derivatives"
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Indisetron Dihydrochloride
CAS:<p>Indisetron Dihydrochloride is a 5-HT(3) and 5-HT(4) receptor antagonist. Indisetron reduces 2-methyl-5-serotonin (HT)-induced bradycardia.</p>Formula:C17H24ClN5OColor and Shape:SolidMolecular weight:349.86Levobunolol
CAS:<p>Levobunolol is a nonselective beta-blocker. It is used topically to treat glaucoma.</p>Formula:C17H25NO3Color and Shape:White To Pink PowderMolecular weight:291.39Tropatepine
CAS:<p>Tropatepine: oral anticholinergic, treats extrapyramidal symptoms, anti-Parkinson's.</p>Formula:C22H23NSColor and Shape:SolidMolecular weight:333.49Riodoxol
CAS:<p>Riodoxol is an antiviral agent that effectively affects the reproduction and maturation of viruses.</p>Formula:C6H3I3O2Color and Shape:SolidMolecular weight:487.8Isopropamide
CAS:<p>Isopropamide (R5) is a long-acting anticholinergic for treating peptic ulcers and excessive gastric acid.</p>Formula:C23H33N2OColor and Shape:SolidMolecular weight:353.52Clonidine
CAS:<p>Clonidine (Kapvay): central alpha-adrenergic agonist, antihypertensive, often combined, not tied to liver issues.</p>Formula:C9H9Cl2N3Purity:99.42% - 99.44%Color and Shape:Crystals SolidMolecular weight:230.09BP-5-087
CAS:<p>BP-5-087 is a STAT3 inhibitor, combining with BCR-ABL1 inhibition to overcome kinase-independent resistance in chronic myeloid leukemia.</p>Formula:C36H30F8N2O6SColor and Shape:SolidMolecular weight:770.69Ivaltinostat
CAS:<p>CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.</p>Formula:C24H33N3O4Purity:98%Color and Shape:SolidMolecular weight:427.54Almokalant
CAS:<p>Almokalant: Class III antiarrhythmic, K+ channel blocker, inhibits Ikr current.</p>Formula:C18H28N2O3SPurity:98%Color and Shape:SolidMolecular weight:352.49TAPI-1
CAS:<p>TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.</p>Formula:C26H37N5O5Purity:≥95%Color and Shape:SolidMolecular weight:499.6LPA2 antagonist 1
CAS:<p>LPA2 antagonist 1 is a potent LPA2 antagonist.</p>Formula:C20H23Cl2N5O2S2Purity:99.85%Color and Shape:SolidMolecular weight:500.47Daltroban
CAS:<p>Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.</p>Formula:C16H16ClNO4SPurity:99.74%Color and Shape:SolidMolecular weight:353.82Benproperine
CAS:<p>Benproperine is a bioactive molecule with antineoplastic properties.</p>Formula:C21H27NOPurity:98%Color and Shape:SolidMolecular weight:309.45Repirinast
CAS:<p>Repirinast is a mediator release inhibitor. It is used to treat asthma.</p>Formula:C20H21NO5Color and Shape:SolidMolecular weight:355.38Procarbazine free base
CAS:<p>Procarbazine: chemo drug for Hodgkin's, brain cancer; liver-activated; MAO inhibitor.</p>Formula:C12H19N3OPurity:98%Color and Shape:SolidMolecular weight:221.3Sarafloxacin
CAS:<p>Sarafloxacin (A56620) has antibacterial activities against Gram-positive and Gram-negative bacteria.</p>Formula:C20H17F2N3O3Purity:98.07% - 98.94%Color and Shape:SolidMolecular weight:385.36Enadoline (Free Base)
CAS:<p>Enadoline is a K-opioid agonist with visual and dissociative effects, studied for pain but dropped due to dysphoria.</p>Formula:C24H32N2O3Color and Shape:SolidMolecular weight:396.52Piribedil dihydrochloride
CAS:<p>dopamine agonist</p>Formula:C16H20Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:371.26Vasicinone
CAS:<p>Vasicinone may act as a hepatoprotective agent.</p>Formula:C11H10N2O2Purity:98.06%Color and Shape:SolidMolecular weight:202.21Hemustine
CAS:<p>Hemustine is an inhibitor of human glutathione reductase and widely used as an anti-tumor agent.</p>Formula:C5H10ClN3O3Color and Shape:SolidMolecular weight:195.6Gilteritinib hemifumarate
CAS:<p>Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment of</p>Formula:C29H44N8O3C4H4O4Purity:99.78%Color and Shape:SolidMolecular weight:610.75Afacifenacin
CAS:<p>Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.</p>Formula:C27H26F3N3O2Purity:99.83%Color and Shape:SolidMolecular weight:481.51Zuclopenthixol decanoate
CAS:<p>Zuclopenthixol decanoate is an anti-schizophrenia drug.</p>Formula:C32H43ClN2O2SPurity:98%Color and Shape:SolidMolecular weight:555.21Oxyphenbutazone monohydrate
CAS:<p>Oxyphenbutazone monohydrate: Phenylbutazone derivative, anti-inflammatory, non-selective COX inhibitor, kills dormant M. tuberculosis.</p>Formula:C19H22N2O4Color and Shape:SolidMolecular weight:342.39Enflicoxib
CAS:<p>Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.</p>Formula:C16H12F5N3O2SPurity:99.88%Color and Shape:SolidMolecular weight:405.34Atomoxetine
CAS:<p>Atomoxetine (HSDB 7352) is a selective norepinephrine inhibitor that may cause an increase in blood pressure by increasing norepinephrine concentrations in</p>Formula:C17H21NOPurity:98%Color and Shape:SolidMolecular weight:255.35Moricizine
CAS:<p>Moricizine is an antiarrhythmia agent which is used primarily for ventricular rhythm disturbances.</p>Formula:C22H25N3O4SPurity:98%Color and Shape:SolidMolecular weight:427.52Nifekalant hydrochloride
CAS:<p>Nifekalant hydrochloride is an IKr potassium channel blocker with an IC50 of 10 µM.</p>Formula:C19H28ClN5O5Purity:99.91%Color and Shape:SolidMolecular weight:441.91Ivabradine
CAS:<p>Ivabradine: oral HCN blocker, lowers heart rate without affecting blood pressure, has anticonvulsant and anti-anginal properties.</p>Formula:C27H36N2O5Color and Shape:SolidMolecular weight:468.59TAPI-0
CAS:<p>TAPI-0 is a matrix metalloprotease (MMP) and TACE inhibitor.</p>Formula:C24H32N4O5Color and Shape:SolidMolecular weight:456.53PF-00356231 hydrochloride
CAS:<p>PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM.</p>Formula:C25H21ClN2O3SPurity:98.39%Color and Shape:SolidMolecular weight:464.96Bifeprunox Mesylate
CAS:<p>Bifeprunox: partial dopamine/serotonin agonist for schizophrenia; suppresses VTA neurons via D2; affects rat nicotine-seeking.</p>Formula:C25H27N3O5SPurity:98%Color and Shape:SolidMolecular weight:481.56PPNDS
CAS:<p>P2X1 receptor antagonist</p>Formula:C18H15N4NaO14PS2Purity:98%Color and Shape:SolidMolecular weight:629.42RS-104966
CAS:<p>RS-104966 is an inhibitor of collagenase that acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1.</p>Formula:C19H21NO6SPurity:98%Color and Shape:SolidMolecular weight:391.44TAK-875 Hemihydrate
CAS:<p>TAK-875 Hemihydrate (Fasiglifam) is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.</p>Formula:C29H32O7SH2OPurity:98%Color and Shape:SolidMolecular weight:533.63(Rac)-Tanomastat
CAS:<p>Tanomastat (BAY 12-9566) is an oral biphenyl MMP inhibitor; blocks MMP-2, -3, -9, -13, with anti-invasive and anti-metastatic properties.</p>Formula:C23H19ClO3SColor and Shape:SolidMolecular weight:410.91(R)-ND-336
CAS:<p>(R)-ND-336: potent, selective MMP-9 inhibitor (K i = 19 nM); inhibits MMP-2 (127 nM), MMP-14 (119 nM); studied for diabetic foot ulcers.</p>Formula:C16H18ClNO3S2Color and Shape:SolidMolecular weight:371.89BR351
CAS:<p>BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).</p>Formula:C20H25FN2O5SPurity:98%Color and Shape:SolidMolecular weight:424.49MMP-2/9-IN-1
CAS:<p>MMP-2/9-IN-1 (Compound 4a) is a potent dual inhibitor of MMP-2 (IC50: 56 nM) and MMP-9 (IC50: 38 nM). leading to DNA fragmentation.</p>Formula:C14H16IN7SColor and Shape:SolidMolecular weight:441.29Pipotiazine
CAS:<p>Pipotiazine treats chronic schizophrenia with less sedation, low hypotension risk, but high extrapyramidal side effects.</p>Formula:C24H33N3O3S2Color and Shape:SolidMolecular weight:475.67Guanfacine
CAS:<p>Guanfacine is a selective agonist of the α2A receptor.</p>Formula:C9H9Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:246.09Rolapitant
CAS:<p>Rolapitant Hydrochloride is an oral NK1-receptor blocker that prevents nausea and has a fast onset and long half-life.</p>Formula:C25H26F6N2O2Purity:99.86%Color and Shape:SolidMolecular weight:500.48Arasertaconazole
CAS:<p>Arasertaconazole, a sterol-14-alpha demethylation inhibitor, is used potentially for the treatment of vulvovaginal candcanidiasis.</p>Formula:C20H15Cl3N2OSColor and Shape:SolidMolecular weight:437.77Esreboxetine
CAS:<p>Esreboxetine( PNU-165442, (S,S) -reboxetine) is a selective inhibitor of norepinephrine reuptake.</p>Formula:C19H23NO3Color and Shape:SolidMolecular weight:313.39Pirbuterol
CAS:<p>Pirbuterol, a short-acting β2 adrenoreceptor agonist, has bronchodilating action used in the treatment of asthma.</p>Formula:C12H20N2O3Color and Shape:SolidMolecular weight:240.3Mianserin
CAS:<p>Mianserin, an H1 receptor reverse agonist, is a psychoactive compound in the tetracyclic antidepressant (TeCA) treatment family.</p>Formula:C18H20N2Purity:99.85%Color and Shape:SolidMolecular weight:264.36cis-Tadalafil
CAS:<p>Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.</p>Formula:C22H19N3O4Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:389.4 g/molBR351 precursor
CAS:<p>BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).</p>Formula:C27H32N2O8S2Purity:98%Color and Shape:SolidMolecular weight:576.68NBI-42902
CAS:<p>NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.</p>Formula:C27H24F3N3O3Color and Shape:SolidMolecular weight:495.49Vernakalant
CAS:<p>Vernakalant (RSD-1235) is a mixed ion channel blocker.</p>Formula:C20H31NO4Purity:98%Color and Shape:SolidMolecular weight:349.46Ketotifen
CAS:<p>Ketotifen: Oral H1 blocker & mast cell stabilizer, inhibits 6-phosphogluconate dehydrogenase, antiviral, for EAE & asthma prevention research.</p>Formula:C19H19NOSColor and Shape:SolidMolecular weight:309.43CP 93129 dihydrochloride
CAS:<p>5-HT1B agonist, potent and highly selective</p>Formula:C12H14ClN3OPurity:98%Color and Shape:SolidMolecular weight:251.71Thiorphan disulfide
CAS:<p>Thiorphan disulfide: Racecadotril impurity; antidiarrheal; limits water/electrolyte intestinal absorption.</p>Formula:C24H28N2O6S2Color and Shape:SolidMolecular weight:504.62NNGH
CAS:<p>NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane-binding.</p>Formula:C13H20N2O5SPurity:98.41%Color and Shape:SolidMolecular weight:316.37Indenolol
CAS:<p>Indenolol is a blocker of beta-adrenergic.</p>Formula:C15H21NO2Purity:98%Color and Shape:SolidMolecular weight:247.33WAY 629
CAS:<p>WAY 629 is a selective SR-2C agonist that also act as potent 5-HT2C receptor agonists.</p>Formula:C15H18N2Color and Shape:SolidMolecular weight:226.32Distigmine Bromide
CAS:<p>Distigmine Bromide is an acetylcholinesterase inhibitor. It is used for the treatment of underactive neurogenic bladder and myasthenia gravis.</p>Formula:C22H32BrN4O4Purity:98%Color and Shape:SolidMolecular weight:496.42Clencyclohexerol
CAS:<p>Clencyclohexerol, like clenbuterol, is a β-adrenoceptor agonist with potential in muscle disorders but poses cardiovascular risks at high doses.</p>Formula:C14H20Cl2N2O2Color and Shape:SolidMolecular weight:319.23(R)-Carvedilol
CAS:<p>(R)-Carvedilol is a non-selective blocker of β/α-1. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).</p>Formula:C24H26N2O4Purity:98%Color and Shape:SolidMolecular weight:406.47(R)-Azelastine
CAS:<p>(R)-Azelastine, an antihistamine, reduces H1R, M1R, M3R levels and inhibits HNEpC growth.</p>Formula:C22H24ClN3OColor and Shape:SolidMolecular weight:381.91-Oxo mirtazapine
CAS:<p>1-Oxo mirtazapine is a metabolite of mirtazapine. It is a synthetic compound and is not found in nature. This product is a research and development impurity standard for the preparation of drug product, which has been synthesized to be highly pure. The material is used for drug development, including pharmacopoeia requirements for analytical studies and metabolism studies. 1-Oxo mirtazapine has been shown to have niche applications in pharmacopoeia and as an HPLC standard.</p>Formula:C17H17N3OPurity:Min. 95%Molecular weight:279.34 g/molDesfluoro ezetimibe
CAS:<p>Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.</p>Formula:C24H22FNO3Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:391.43 g/molN-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:<p>N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.</p>Formula:C12H9F3N2O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:270.21 g/molMoveltipril
CAS:<p>Moveltipril (Moveltipril calcium) is a potent angiotensin-converting enzyme (ACE) inhibitor.Moveltipril is converted to captopril in the body for action.</p>Formula:C19H30N2O5SPurity:97.55% - 98.28%Color and Shape:SolidMolecular weight:398.52CP-544439
CAS:<p>CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development.</p>Formula:C18H19FN2O6SPurity:95.02% - 98.66%Color and Shape:SolidMolecular weight:410.42Empagliflozin S-furanose
CAS:<p>Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.</p>Formula:C23H27ClO7Purity:Min. 95%Color and Shape:PowderMolecular weight:450.91 g/molLaduviglusib trihydrochloride
CAS:<p>Laduviglusib trihydrochloride, a GSK-3α/β inhibitor (IC50: 10/6.7 nM), activates Wnt/β-catenin signaling and induces autophagy.</p>Formula:C22H20Cl5N8Purity:99.34%Color and Shape:SolidMolecular weight:573.71Arimoclomol
CAS:<p>Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (</p>Formula:C14H20ClN3O3Purity:99.15%Color and Shape:SolidMolecular weight:313.78(R,R)-Montelukast bis-sulfide
CAS:<p>(R,R)-Montelukast bis-sulfide is a drug product that is used in the analytical and research and development of drugs. It is also used as an impurity standard for HPLC. (R,R)-Montelukast bis-sulfide has been shown to have niche applications in drug development and research, as well as being a high purity API.</p>Formula:C41H46ClNO5S2Purity:90%MinMolecular weight:732.39 g/molPitavastatin N-oxide
CAS:<p>Pitavastatin N-oxide is a drug product that is an analytical standard and natural API impurity. It is used in the synthesis of other drugs, such as pitavastatin, which is a statin drug used to lower cholesterol levels. Pitavastatin N-oxide has been shown to be a potent inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) to mevalonate. This inhibits cholesterol production and lowers levels of low density lipoprotein (LDL) cholesterol in the blood.</p>Formula:C25H24FNO5Purity:Min. 95%Molecular weight:437.46 g/molAmiodarone impurity E
CAS:<p>Amiodarone impurity E is a nucleophilic compound that is synthesized by the acylation of a diazonium salt with an amine. It has been shown to be active against staphylococci, but not against subtilis. The reaction may be catalyzed by acid or chloride. Amiodarone impurity E is also demethylated and dehydrated to form the final product, amiodarone.</p>Formula:C19H18O3Purity:Min. 95%Color and Shape:PowderMolecular weight:294.34 g/molBrivaracetam CV
CAS:Controlled ProductLactams, nesoiFormula:C11H20N2O2Color and Shape:White Off-White SolidMolecular weight:212.15248Pantoprazole sulphide
CAS:<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>Formula:C16H15F2N3O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:367.37 g/molN-De[2-(methylsulfonyl)ethyl] lapatinib
CAS:<p>Lapatinib is a tyrosine kinase inhibitor that blocks the epidermal growth factor receptor (EGFR) and other tyrosine kinases. It is used in cancer treatment to inhibit tumor growth, with a high success rate. Lapatinib is also used to treat lung cancer and other types of cancer. The drug has been shown to inhibit EGFR phosphorylation in vitro, which leads to inhibition of cell proliferation and induction of apoptosis. Lapatinib also inhibits the expression of EGFR downstream target genes such as b-raf, serine/threonine-protein kinase, and cyp3a5.</p>Formula:C26H20ClFN4O2Purity:Min. 95%Molecular weight:474.91 g/molRoflumilast Impurity A
CAS:<p>Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.</p>Formula:C16H14Cl2N2O3Purity:Min. 95%Molecular weight:353.2 g/molEphedrine Hydrochloride
CAS:Controlled ProductEphedrine and its saltsFormula:C10H15NO·HClColor and Shape:White Off-White PowderMolecular weight:201.09204Givinostat hydrochloride
CAS:<p>Givinostat HCl (ITF2357 HCl) inhibits HDAC1/3 (IC50: 198/157 nM) with anti-inflammatory, anti-angiogenic, and antineoplastic properties.</p>Formula:C24H28ClN3O4Purity:99.39%Color and Shape:SolidMolecular weight:457.95Sovaprevir
CAS:<p>Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.</p>Formula:C43H53N5O8SPurity:99.11%Color and Shape:SolidMolecular weight:799.97Ezetimibe ketone
CAS:<p>Ezetimibe ketone is a lipid-lowering agent that inhibits cholesterol absorption through the inhibition of Niemann-Pick C1-like 1 (NPC1L1). Ezetimibe ketone is used to reduce the levels of low-density lipoprotein cholesterol (LDL-C) in patients with primary hypercholesterolemia, sitosterolemia, and familial combined hyperlipidemia. Ezetimibe ketone has been shown to be bioequivalent to ezetimibe, which is an oral drug that inhibits cholesterol absorption by blocking NPC1L1. The drug binds to the NPC1L1 receptor in the brush border membrane of enterocytes and prevents cholesterol uptake. Ezetimibe ketone has a high solubility in organic solvents such as dichloromethane or chloroform. It also has a high melting point, which makes it suitable for use on chromatographic columns.</p>Formula:C24H19F2NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:407.41 g/molApixaban Impurity 1
CAS:<p>Apixaban Impurity 1 is an impurity found in Apixaban, a drug used for the prevention of stroke. It is produced by condensation of 2-aminopyridine and 3-hydroxybenzaldehyde in ethanol with sodium hydroxide as a catalyst. The reaction proceeds via amination of the pyridine ring followed by transesterification. The yield of this impurity is low at about 4%.</p>Purity:Min. 95%Linagliptin impurity G
CAS:<p>Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.</p>Formula:C25H28N8O2Purity:Min. 95%Color and Shape:PowderMolecular weight:472.54 g/molEltenac
CAS:<p>Eltenac, a cyclooxygenase (COX) inhibitor, is used potentially for the treatment of pain.</p>Formula:C12H9Cl2NO2SPurity:98.53%Color and Shape:SolidMolecular weight:302.18Vildagliptin related compound F
CAS:<p>Vildagliptin related compound F (VRCF) is a drug product that has been custom synthesized. VRCF is a high purity, analytical standard. It is metabolized in the body and can be used as a research and development standard to study the metabolism of vildagliptin. VRCF is a natural metabolite that has been identified as an impurity in the drug product Vildagliptin. VRCF has not been recognized by the USP or EP for use as an impurity standard. CAS no: 1789703-36-1</p>Formula:C17H24N2O3Purity:Min. 95%Color and Shape:PowderMolecular weight:304.4 g/molBenperidol
CAS:<p>Benperidol (Anquil), a butanone derivative, has antipsychotic effects and blocks D2 receptors; useful in PET scans.</p>Formula:C22H24FN3O2Purity:99.91%Color and Shape:SolidMolecular weight:381.44Ecopipam
CAS:<p>Ecopipam: orally active, selective dopamine D1/D5 antagonist (Ki: 1.2 nM/2.0 nM). 40x more selective over D2/D4/5-HT/α2a. For schizophrenia, obesity research.</p>Formula:C19H20ClNOPurity:99.68%Color and Shape:SolidMolecular weight:313.82(Z)-Thiothixene
CAS:<p>(Z)-Thiothixene (Thiothixene) is an antagonist of serotonergic receptor.</p>Formula:C23H29N3O2S2Purity:99.21%Color and Shape:Yellow To Yellow With A Tan Cast PowderMolecular weight:443.63AGPS-IN-2i
CAS:<p>AGPS-IN-2i inhibits alkylglycerol phosphate synthase, affecting ether lipid metabolism and reducing cancer cell migration and proliferation.</p>Formula:C18H17F2N3O2Purity:98.92%Color and Shape:SolidMolecular weight:345.34Edoxaban
CAS:<p>Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.</p>Formula:C24H30ClN7O4SPurity:97.67% - 99.71%Color and Shape:SolidMolecular weight:548.06Imipramine
CAS:<p>Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.</p>Formula:C19H24N2Purity:99.4%Color and Shape:White To Off-White /Hydrochloride/ SolidMolecular weight:280.41Amlodipine EP Impurity E maleate
CAS:<p>Amlodipine EP Impurity E maleate is a high purity and analytical grade chemical. It is a metabolite of Amlodipine, which is used in the treatment of hypertension. This chemical has been shown to be a natural product that is produced by the human body. It also has been shown to have pharmacological properties, such as anti-inflammatory and vasodilatory effects. The impurity standard for this compound is available from Sigma-Aldrich.br>br></p>Formula:C21H27ClN2O5•C4H4O4Purity:Min. 95%Molecular weight:538.98 g/mol1-Fluoronaphthalene
CAS:<p>1-Fluoronaphthalene is a polyunsaturated compound that is used in analytical chemistry for the determination of test samples. It is an inhibitor of the enzyme IDO1, which plays an important role in the regulation of immune function, and has been shown to have anti-inflammatory properties. 1-Fluoronaphthalene can be synthesized by reacting n-dimethyl formamide with hydrogen fluoride and then adding a diazonium salt and hydrochloric acid. The UV absorption spectrum of 1-fluoronaphthalene displays a maximum at 248 nm. This compound binds to cation channels on cells, causing hyperpolarization.</p>Formula:C10H7FPurity:Min. 95%Molecular weight:146.16 g/molethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS:<p>Please enquire for more information about ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C22H22N4O4Purity:Min. 95%Molecular weight:406.43 g/molDimethindene
CAS:<p>Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.</p>Formula:C20H24N2Purity:98.3% - 98.99%Color and Shape:SolidMolecular weight:292.42Vildagliptin Related Compound 2
CAS:<p>Vildagliptin Related Compound 2 is a synthetic compound that has been shown to be an inhibitor of DPP-4. It is a white solid that can be synthesized by condensation of vildagliptin with chloroacetyl chloride in the presence of an alkali. The compound was found to have impurities, including 1-(2-chlorophenyl)ethanol and 3-chlorobenzaldehyde.</p>Formula:C17H25N3O2Purity:Min. 95%Molecular weight:303.4 g/molViloxazine
CAS:<p>Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity</p>Formula:C13H19NO3Purity:99.67%Color and Shape:SolidMolecular weight:237.29UNC0321
CAS:<p>UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.</p>Formula:C27H45N7O3Purity:99.80%Color and Shape:SolidMolecular weight:515.69Apixaban Impurity 6
CAS:<p>Please enquire for more information about Apixaban Impurity 6 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C26H26N4O5Purity:Min. 95%Molecular weight:474.51 g/molAmlodipine EP Impurity F maleate
CAS:<p>Amlodipine EP Impurity F maleate is an impurity of amlodipine, a drug product. It is a natural substance that has been classified as an API impurity in the United States Pharmacopeia (USP). The chemical name for this drug is 3-(2-chlorophenyl)-1-methyl-5-(o-tolyloxy)-2,4-dihydro-6H-[1,3]thiazolo[3,2-a]pyrimidin-7-one. Amlodipine EP Impurity F maleate has the following properties: C12H9ClNO2S and a melting point of 210°C with a purity of 99.5%. This compound was synthesized by custom synthesis and is used as an analytical standard for HPLC. This compound was also used during the development of amlodipine to determine its metabolism studies.</p>Formula:C19H23ClN2O5•C4H4O4Purity:Min. 95%Molecular weight:510.92 g/molGemigliptin
CAS:<p>Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)</p>Formula:C18H19F8N5O2Purity:99.72%Color and Shape:SolidMolecular weight:489.36Vildagliptin carboxylic acid methyl ester
CAS:<p>Please enquire for more information about Vildagliptin carboxylic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C18H28N2O4Purity:Min. 95%Molecular weight:336.43 g/molCyamemazine
CAS:<p>Cyamemazine is an antipsychotic compound with sedative and anxiolytic activity.Cyamemazine is a 5-HT3, 5-HT2A, and 5-HT2C receptor antagonist.</p>Formula:C19H21N3SPurity:97.01%Color and Shape:SolidMolecular weight:323.46(R)-Zanubrutinib
CAS:<p>(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).</p>Formula:C27H29N5O3Purity:99.55%Color and Shape:SolidMolecular weight:471.553-Trifluoroacetylamino linagliptin
CAS:<p>Please enquire for more information about 3-Trifluoroacetylamino linagliptin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C27H27F3N8O3Purity:Min. 95%Molecular weight:568.55 g/molPG-116800
CAS:<p>PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.</p>Formula:C24H27N3O7SPurity:98.03% - 99.66%Color and Shape:SolidMolecular weight:501.55Stepronin
CAS:<p>Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.</p>Formula:C10H11NO4S2Purity:99.59%Color and Shape:White Or Off White CrystallineMolecular weight:273.33(S)-Rabeprazole sodium
CAS:<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>Formula:C18H21N3O3S•NaPurity:Min. 95%Molecular weight:382.43 g/mol2,3,4,5-Tetradehydro alfuzosin hydrochloride
CAS:<p>Alfuzosin is a potent, selective, and long-acting α1A-adrenergic receptor antagonist. It is used to treat benign prostatic hyperplasia (BPH) in males. Alfuzosin is also used as an antihypertensive agent, for the treatment of pheochromocytoma, and for the treatment of benign prostatic hyperplasia in males. The hydrogenation of 2,3,4,5-tetradehydroalfuzosin to alfuzosin hydrochloride is performed by liquid hydrogenation or by hydrogenation on a palladium catalyst in a mixture of dimethylformamide and hexamethylphosphoramide. This process minimizes the formation of impurities such as 2,3,4-trimethoxy alfuzosin.</p>Formula:C19H24ClN5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:421.88 g/molMMP-2/MMP-9 Inhibitor I
CAS:<p>MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.</p>Formula:C21H19NO4SPurity:99.74%Color and Shape:SolidMolecular weight:381.44Gallopamil
CAS:<p>Gallopamil blocks acid secretion (IC50: 10.9 μM), acts as antiarrhythmic, vasodilator, and is a methoxy Verapamil derivative.</p>Formula:C28H40N2O5Purity:99.85%Color and Shape:SolidMolecular weight:484.63MMP2-IN-3
CAS:<p>MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM).</p>Formula:C23H21N3OPurity:99.38%Color and Shape:SolidMolecular weight:355.43Fenoverine
CAS:<p>Fenoverine (Spasmopriv) has antispasmodic activity and can be used to study gastrointestinal spasms.</p>Formula:C26H25N3O3SPurity:98.34%Color and Shape:SolidMolecular weight:459.56Pitolisant
CAS:<p>Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human histamine H3 receptor with Ki of 0.16 nM.</p>Formula:C17H26ClNOPurity:99.84%Color and Shape:SolidMolecular weight:295.85Pramipexole EP Impurity C
CAS:<p>Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.</p>Formula:C20H32N6S2Purity:Min. 95%DB04760
CAS:<p>DB04760: selective MMP-13 inhibitor, non-zinc-chelating, IC50=8nM, reduces paclitaxel neurotoxicity, anticancer.</p>Formula:C22H20F2N4O2Purity:99.93% - 99.99%Color and Shape:SolidMolecular weight:410.42MMP-9 Inhibitor I
CAS:<p>MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively).</p>Formula:C27H33N3O5SColor and Shape:SolidMolecular weight:511.63Quizalofop
CAS:<p>Quizalofop (Xylafop) is a reagent of biochemical.</p>Formula:C17H13ClN2O4Purity:97.14%Color and Shape:SolidMolecular weight:344.75Thioquinapiperifil
CAS:<p>Thioquinapiperifil is a type of phosphodiesterase-5 (PDE-5) inhibitor found in dietary supplements.</p>Formula:C24H28N6OSPurity:98%Color and Shape:SolidMolecular weight:448.58LY52
CAS:<p>LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.</p>Formula:C22H24N4O6Purity:98%Color and Shape:SolidMolecular weight:440.45XL-784 free base
CAS:<p>XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).</p>Formula:C21H22ClF2N3O8SPurity:98%Color and Shape:SolidMolecular weight:549.93IK-862
CAS:<p>IK-862 is a selective TACE inhibitor with potential anti-inflammatory and anticancer activity for the study of neuritis.</p>Formula:C25H27N3O4Purity:97.75% - 98.29%Color and Shape:SolidMolecular weight:433.5Cipemastat
CAS:<p>Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).</p>Formula:C22H36N4O5Purity:98%Color and Shape:SolidMolecular weight:436.55Gisadenafil
CAS:<p>Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.</p>Formula:C23H33N7O5SPurity:98.82% - 99.50%Color and Shape:SolidMolecular weight:519.62MMP-145
CAS:<p>MMP-145 is used as a protease inhibitor.</p>Formula:C20H20N2O7SPurity:98%Color and Shape:SolidMolecular weight:432.45Frovatriptan
CAS:<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Formula:C14H17N3OColor and Shape:SolidMolecular weight:243.3Naxagolide free base
CAS:<p>Naxagolide is a sustained release formulation. It is a dopamine agonist.</p>Formula:C15H21NO2Purity:98%Color and Shape:SolidMolecular weight:247.33Brasofensine
CAS:<p>Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.</p>Formula:C16H20Cl2N2OColor and Shape:SolidMolecular weight:327.25Inz-1
CAS:<p>Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.</p>Formula:C16H14N2O2Purity:99.55% - 99.88%Color and Shape:SolidMolecular weight:266.29MMP-7-IN-3
CAS:<p>MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.</p>Formula:C34H43ClF3N7O9SPurity:99.915%Color and Shape:SolidMolecular weight:818.26Ubrogepant
CAS:<p>Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.</p>Formula:C29H26F3N5O3Purity:99.452% - 99.78%Color and Shape:SolidMolecular weight:549.54Ro 32-7315
CAS:<p>Ro 32-7315 is a selective inhibitor of ADAM17.</p>Formula:C22H35N3O5SPurity:98%Color and Shape:SolidMolecular weight:453.6Pirtobrutinib
CAS:<p>Pirtobrutinib: a selective, non-covalent BTK inhibitor effective against BTK C481 mutations, causing tumor regression in lymphoma models.</p>Formula:C22H21F4N5O3Purity:99.76% - 99.94%Color and Shape:SolidMolecular weight:479.43Bufuralol
CAS:<p>Bufuralol (Ro 3-4787) is a 尾-adrenergic receptor blocker with a certain degree of sympathomimetic effects and can be used to study cardiovascular diseases.</p>Formula:C16H23NO2Purity:98.26%Color and Shape:SolidMolecular weight:261.36ONO 4817
CAS:<p>ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.</p>Formula:C22H28N2O6Color and Shape:SolidMolecular weight:416.47(Rac)-Lonafarnib
CAS:<p>(Rac)-Lonafarnib is a racemic FTase inhibitor, effective against H-ras, K-ras, N-ras (IC50: 1.9, 5.2, 2.8 nM), and has anti-HDV properties.</p>Formula:C27H31Br2ClN4O2Color and Shape:SolidMolecular weight:638.82Tianagliflozin
CAS:<p>Tianagliflozin, a sodium/glucose cotransporter 2 (SGLT-2) inhibitor, is used potentially for the treatment of type 2 diabetes.</p>Formula:C21H25ClO5Purity:98%Color and Shape:SolidMolecular weight:392.87Carmoxirole hydrochloride
CAS:<p>Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.</p>Formula:C24H27ClN2O2Purity:99.37% - 99.62%Color and Shape:SolidMolecular weight:410.94RU 58668
CAS:<p>Pure antiestrogen that downregulates estrogen receptor expression</p>Formula:C34H43F5O5SPurity:98%Color and Shape:SolidMolecular weight:658.76XL-784
CAS:<p>XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.</p>Formula:C42H42Cl2F4MgN6O16S2Purity:98%Color and Shape:SolidMolecular weight:1122.15MMP3 inhibitor 1
CAS:<p>MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).</p>Formula:C23H31N3O6SPurity:98%Color and Shape:SolidMolecular weight:477.57Celiprolol hydrochloride
CAS:<p>Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.</p>Formula:C20H33N3O4·HClColor and Shape:White Crystalline SolidMolecular weight:415.96Fluvalinate
CAS:<p>Fluvalinate is a synthetic chemical compound and can be commonly used to control varroa mites in honey bee colonies.</p>Formula:C26H22ClF3N2O3Color and Shape:SolidMolecular weight:502.91Mefenidil
CAS:<p>Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model.</p>Formula:C12H11N3Purity:98.27%Color and Shape:SolidMolecular weight:197.24Caroverine
CAS:<p>Caroverine is a potential chemotherapeutical agent in HNSCC cell lines.</p>Formula:C22H27N3O2Color and Shape:SolidMolecular weight:365.47KB-R7785
CAS:<p>KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.</p>Formula:C18H27N3O4Color and Shape:SolidMolecular weight:349.42Gepirone
CAS:<p>Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.</p>Formula:C19H29N5O2Purity:99.35% - 99.89%Color and Shape:SolidMolecular weight:359.47ROCK2-IN-7
CAS:<p>ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis.</p>Formula:C26H28FN5OPurity:98%Color and Shape:SolidMolecular weight:445.53Dothiepin
CAS:<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Formula:C19H21NSPurity:98%Color and Shape:SolidMolecular weight:295.44TP0556351
CAS:<p>TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.</p>Formula:C50H70N10O16Purity:98%Color and Shape:SolidMolecular weight:1067.15MMP-3 Inhibitor VIII
CAS:<p>Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, is a critical enzyme involved in tissue remodeling and repair through its role in degrading extracellular matrix proteins, facilitating cell migration. This enzyme has been implicated in various physiological processes including vascular remodeling associated with aneurysm formation, wound healing, the progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII, a cell-permeable sulfonamide-based hydroxamic acid, effectively inhibits MMP-3 by binding to its active site (Ki = 23 nM), thus blocking its enzymatic activity. Additionally, this inhibitor has been demonstrated to suppress the activity of mouse macrophage metalloelastase MME/MMP-12, with an IC50 value of 13 nM, highlighting its potential utility in research on tissue remodeling and disease processes involving MMPs.</p>Formula:C20H26N2O5SColor and Shape:SolidMolecular weight:406.5Etidocaine Hydrochloride
CAS:<p>Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel.</p>Formula:C17H29ClN2OPurity:99.86%Color and Shape:SolidMolecular weight:312.88Ro 31-9790
CAS:<p>Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).</p>Formula:C15H29N3O4Purity:98%Color and Shape:SolidMolecular weight:315.41Cobimetinib racemate
CAS:<p>Cobimetinib racemate (Cobimetinib (racemate)) (GDC-0973 racemate) is a selective inhibitor of MEK.Cobimetinib racemate is also known as a mitogen-activated</p>Formula:C21H21F3IN3O2Purity:98.00% - 99.71%Color and Shape:SolidMolecular weight:531.31Bufuralol (hydrochloride)
CAS:<p>Bufuralol hydrochloride is a potent, non-selective, orally active β-blocker with partial agonist effects and a CYP2D6 probe.</p>Formula:C16H24ClNO2Color and Shape:SolidMolecular weight:297.82PIM447
CAS:<p>PIM447 (LGH447) is a pan-PIM kinase inhibitor with anti-tumor and bone protective effects. PIM447 reduces the viability, and motility of HuH6 cell.</p>Formula:C24H23F3N4OPurity:98.97%Color and Shape:SolidMolecular weight:440.46Dibenamine hydrochloride
CAS:<p>Dibenamine hydrochloride is a competitive and irreversible blocking agent of the β-adrenergic receptor.</p>Formula:C16H19Cl2NPurity:96.43%Color and Shape:Oily Liquid SolidMolecular weight:296.23LX7101
CAS:<p>LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).</p>Formula:C23H29N7O3Purity:99.08%Color and Shape:SolidMolecular weight:451.52Z-PDLDA-NHOH
CAS:<p>Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].</p>Formula:C22H32N4O6Color and Shape:SolidMolecular weight:448.51ICI 204448
CAS:<p>ICI 204448 is a potent and peripherally selective κ-opioid agonist.</p>Formula:C23H26Cl2N2O4Color and Shape:SolidMolecular weight:465.37Zandelisib
CAS:<p>Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.</p>Formula:C31H38F2N8OPurity:99.88%Color and Shape:SolidMolecular weight:576.68AZD-1656
CAS:<p>AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2</p>Formula:C24H26N6O5Purity:97.07% - 99.37%Color and Shape:SolidMolecular weight:478.5FGIN-1-27
CAS:<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Formula:C28H37FN2OPurity:99.86%Color and Shape:SolidMolecular weight:436.6Collagen proline hydroxylase inhibitor
CAS:<p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>Formula:C18H18N4O4Purity:98%Color and Shape:SolidMolecular weight:354.36Apratastat
CAS:<p>Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)</p>Formula:C17H22N2O6S2Purity:98%Color and Shape:SolidMolecular weight:414.5Yonkenafil
CAS:<p>Yonkenafil, a PDE5 inhibitor, may reduce stroke damage and aid in Alzheimer's treatment.</p>Formula:C24H33N5O4SColor and Shape:SolidMolecular weight:487.61Levocabastine
CAS:<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Formula:C26H29FN2O2Color and Shape:SolidMolecular weight:420.52ND-378
CAS:<p>ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.</p>Formula:C18H19NO4S2Purity:98%Color and Shape:SolidMolecular weight:377.48Saredutant
CAS:<p>Saredutant (SR 48968) is a selective neurokinin-2 (NK2) receptor antagonist that inhibits neurokinin A by blocking NK2 receptor, antidepressant and anxiolytic.</p>Formula:C31H35Cl2N3O2Purity:99.12%Color and Shape:SolidMolecular weight:552.54Ritodrine
CAS:<p>Ritodrine (DU21220) is a β-adrenergic agonist as well as an effective uterine relaxant that can be used in arrest premature labor research[1] [2].</p>Formula:C17H21NO3Color and Shape:SolidMolecular weight:287.35Brilaroxazine
CAS:<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Formula:C22H25Cl2N3O3Purity:99.36%Color and Shape:SolidMolecular weight:450.36MMP-7-IN-2
CAS:<p>MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.</p>Formula:C28H40ClF3N6O9SPurity:97.82%Color and Shape:SolidMolecular weight:729.17MMP13-IN-3
CAS:<p>MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.</p>Formula:C24H22N4O5Purity:99.76%Color and Shape:SolidMolecular weight:446.46Aderamastat
CAS:<p>Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor indicated for the study of allergic asthma, COPD and pulmonary fibrosis.</p>Formula:C21H18N2O4SPurity:99.35%Color and Shape:SolidMolecular weight:394.441-(6-Chloro-9H-carbazol-2-yl)ethanone
CAS:<p>1-(6-Chloro-9H-carbazol-2-yl)ethanone is a chemical substance that belongs to the class of synthetic drugs. It is used as a pharmaceutical intermediate in the production of other chemical substances, including antibiotics and antihypertensives. 1-(6-Chloro-9H-carbazol-2-yl)ethanone has been shown to be metabolized by cytochrome P450 enzymes and by glucuronidases or esterases. This product can also be used as an impurity standard for HPLC analyses of fluoroquinolones.</p>Formula:C14H10ClNOPurity:Min. 95%Molecular weight:243.69 g/molCollagen proline hydroxylase inhibitor-1
CAS:<p>Collagen proline hydroxylase inhibitor-1 具有抗纤维增生活性。</p>Formula:C24H21N5O4Purity:99.62%Color and Shape:SolidMolecular weight:443.45Sitagliptin impurity E
CAS:<p>Sitagliptin impurity E is an inhibitor of dipeptidyl peptidase-4 (DPP-IV) that is used as a hypoglycemic agent. Sitagliptin impurity E has been shown to increase the glucose-lowering effect in diabetic patients with type 2 diabetes mellitus. It is also effective in reducing postprandial glucose and insulin levels. Sitagliptin impurity E has been shown to increase the concentration of insulin in plasma for up to 24 hours after administration, which suggests that it may be useful for the treatment of metabolic disorders such as obesity and type 2 diabetes mellitus.</p>Formula:C16H15F6N5OPurity:Min. 95%Molecular weight:407.31 g/mol7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole
CAS:<p>7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole (7'-MPB) is a benzimidazole derivative that is used as a medicine. It is made from recycled chemicals and has shown to have industrial applications as a catalyst for cyclization reactions. 7'-MPB is also used in the production of benzenesulfonic acid, which is an organic solvent. This chemical has been shown to be effective against high blood pressure, but has not been tested on humans yet. Telmisartan, which belongs to the angiotensin II receptor blocker class of drugs, can inhibit the synthesis of prostaglandins.</p>Formula:C18H18N4Purity:Min. 95%Molecular weight:290.36 g/molMaralixibat Chloride
CAS:<p>Maralixibat Chloride (LUM001 chloride), an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.</p>Formula:C40H56ClN3O4SPurity:99.19% - 99.65%Color and Shape:SolidMolecular weight:710.41Elobixibat
CAS:<p>Elobixibat (A 3309) blocks IBAT in mice/humans/dogs (IC50: 0.13/0.53/5.8 nM); used for constipation research.</p>Formula:C36H45N3O7S2Purity:97.43% - 98.03%Color and Shape:SolidMolecular weight:695.894-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride
CAS:<p>4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride is a drug product. It is used as an analytical standard and in the development of drugs. The metabolite of 4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride, 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N-(4-nitrophenyl)benzamide, has been shown to inhibit the production of cytokines IL6 and TNFα by human monocytes, macrophages, and dendritic cells. Metabolism studies have shown that 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N</p>Formula:C13H20ClNO3Purity:Min. 95%Molecular weight:273.76 g/molLumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Formula:C24H28FN3OPurity:99.68% - 99.91%Color and Shape:SolidMolecular weight:393.52-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid
CAS:<p>This is a synthetic, impurity standard for 2-Amino-5,6-dichloro-3-(4H)-quinazoline acetic acid (CAS No. 1159977-03-3) that can be used in the drug product development process. This product is available as a custom synthesis and as an analytical standard for HPLC. It is also available as a pharmacopoeia grade material. The compound has been shown to have niche applications in metabolism studies and natural products research.</p>Formula:C10H9Cl2N3O2Purity:Min. 95%Molecular weight:274.1 g/mol11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine
CAS:<p>11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine is a molecule that inhibits the replication of DNA and RNA in viruses. The structure of 11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine has been determined by X-ray crystallography. Hepatocyte cells were used for this study because they are important for the metabolism of drugs. This molecule binds to serine proteases and prevents them from functioning properly. It also inhibits the replication of hepatitis C virus and human immunodeficiency virus type 1 (HIV-1). 11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine can be used as a template for designing other molecules with antiviral</p>Formula:C30H24N4S2Purity:Min. 95%Color and Shape:Yellow SolidMolecular weight:504.67 g/molFinafloxacin
CAS:<p>Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.</p>Formula:C20H19FN4O4Color and Shape:SolidMolecular weight:398.39COTI-219
CAS:<p>COTI-219 is an oral inhibitor of KRAS with antitumor properties [1].</p>Formula:C17H18N6SColor and Shape:SolidMolecular weight:338.43SD-2590 HCl
CAS:<p>SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.</p>Formula:C22H26ClF3N2O7SPurity:98%Color and Shape:SolidMolecular weight:554.96RJF02215
CAS:<p>RJF02215, an MMP-9 inhibitor, exhibits growth inhibitory activity against the ovarian cancer cell line SKOV3. It is utilized in tumor research.</p>Formula:C17H12ClN3OS3Color and Shape:SolidMolecular weight:405.95Neptinib
CAS:<p>Neptinib (NEP010), a derivative of Afatinib, exhibits enhanced antitumor properties and improved pharmacokinetics when administered orally. It demonstrates a notable suppression of tumor expansion in mouse models of non-small cell lung cancer harboring various EGFR mutations. Furthermore, Neptinib effectively inhibits the EGFR kinase family, exhibiting IC 50 values of 0.24 nM for EGFR wt, 7.25 nM for EGFR L858R/T790M, 0.46 nM for EGFR L858R, and 1.79 nM for EGFR T790M.</p>Formula:C22H23ClFN5O2Color and Shape:SolidMolecular weight:443.90UK 356618
CAS:<p>UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).</p>Formula:C34H43N3O4Purity:98%Color and Shape:SolidMolecular weight:557.72SD-7300
CAS:<p>SD-7300 (SC-81490) functions as an orally active inhibitor targeting MMP-2, MMP-9, and MMP-13, exhibiting potent inhibition with K_i values of 0.03, 0.01, and 0.03 nM, respectively. By inhibiting these metalloproteinases, SD-7300 effectively reduces extracellular matrix degradation by tumor cells, thereby curbing their invasion and metastasis. Additionally, this compound acts as a dose-dependent inhibitor of mouse corneal angiogenesis and prevents interleukin-1-induced degradation of bovine cartilage. SD-7300 is applicable in the study of breast cancer.</p>Formula:C21H30F3N3O7SColor and Shape:SolidMolecular weight:525.54ZK159222
CAS:<p>ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.</p>Formula:C32H48O5Purity:98%Color and Shape:SolidMolecular weight:512.72HU-308
CAS:<p>HU-308, a synthetic cannabinoid analogue, is a highly selective agonist of the CB2 receptor. It demonstrates an affinity for the CB2 receptor that is over 440 times greater than its affinity for the CB1 receptor, which are predominantly found in immune cells. This compound plays a crucial role in modulating the immunosuppressive effects of the endocannabinoid system (ECS). Additionally, HU-308 possesses anti-inflammatory and neuroprotective properties, and it regulates the function of microglia. Its potential applications include research into neuroinflammation and retinal diseases.</p>Formula:C27H42O3Color and Shape:SolidMolecular weight:414.62BAY-7598
CAS:<p>BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).</p>Formula:C28H31N3O6Purity:98%Color and Shape:SolidMolecular weight:505.56Macitentan (n-butyl analogue)
CAS:<p>Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.</p>Formula:C20H21Br2N5O4SPurity:98%Color and Shape:SolidMolecular weight:587.29Aclidinium
CAS:<p>Aclidinium, a dual-action compound, serves as a long-acting muscarinic antagonist and a β2-adrenoceptor (β2-AR) agonist, exhibiting bronchodilator properties. It effectively reduces lung hyperinflation, enhances lung function, and prolongs exercise endurance time. This compound is commonly utilized in studies focusing on chronic obstructive pulmonary disease (COPD).</p>Formula:C26H30NO4S2Color and Shape:SolidMolecular weight:484.65CM-352
CAS:<p>CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.</p>Formula:C24H29N3O6SPurity:99.36%Color and Shape:SolidMolecular weight:487.57Vibegron
CAS:<p>Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).</p>Formula:C26H28N4O3Color and Shape:SolidMolecular weight:444.53RuDiOBn
CAS:<p>RuDiOBn exhibits low antioxidant activity by scavenging DPPH and ABTS free radicals with scavenging rates of 13.2% and 5.9% at a concentration of 100 μg/mL. It inhibits collagen glycation and reduces the formation of advanced glycation end-products (AGE) with an IC50 of 2.45 μg/mL. RuDiOBn also enhances fibroblast proliferation and migration, stimulates collagen synthesis, and aids in skin repair and regeneration while inhibiting collagenase.</p>Formula:C29H22O7Color and Shape:SolidMolecular weight:482.481Faldaprevir
CAS:<p>Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.</p>Formula:C40H49BrN6O9SPurity:99.04% - 99.19%Color and Shape:SolidMolecular weight:869.82UK-370106
CAS:<p>UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-</p>Formula:C35H44N2O5Purity:98%Color and Shape:SolidMolecular weight:572.73(3S,4R)-Tofacitinib
CAS:<p>(3S,4R)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib is a JAK3 inhibitor(IC50 : 1 nM).</p>Formula:C16H20N6OPurity:98%Color and Shape:SolidMolecular weight:312.37
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