
Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65495 products of "Quinazoline and Quinoline Derivatives"
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Tofogliflozin
CAS:<p>Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).</p>Formula:C22H26O6Purity:98%Color and Shape:SolidMolecular weight:386.44UK 356618
CAS:<p>UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).</p>Formula:C34H43N3O4Purity:98%Color and Shape:SolidMolecular weight:557.723-Aminobenzene-1,2-diol
CAS:<p>3-Aminobenzene-1,2-diol (compound C8) is an inhibitor of matrix metalloproteinases (MMP), with IC50 values of 20, 26, 16, and 16.3 μM against MMP-2, MMP-8, MMP-9, and MMP-14, respectively.</p>Formula:C6H7NO2Color and Shape:SolidMolecular weight:125.13Vibegron
CAS:<p>Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).</p>Formula:C26H28N4O3Color and Shape:SolidMolecular weight:444.53ZK159222
CAS:<p>ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.</p>Formula:C32H48O5Purity:98%Color and Shape:SolidMolecular weight:512.72RuDiOBn
CAS:<p>RuDiOBn exhibits low antioxidant activity by scavenging DPPH and ABTS free radicals with scavenging rates of 13.2% and 5.9% at a concentration of 100 μg/mL. It inhibits collagen glycation and reduces the formation of advanced glycation end-products (AGE) with an IC50 of 2.45 μg/mL. RuDiOBn also enhances fibroblast proliferation and migration, stimulates collagen synthesis, and aids in skin repair and regeneration while inhibiting collagenase.</p>Formula:C29H22O7Color and Shape:SolidMolecular weight:482.481UK-370106
CAS:<p>UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-</p>Formula:C35H44N2O5Purity:98%Color and Shape:SolidMolecular weight:572.73CM-352
CAS:<p>CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.</p>Formula:C24H29N3O6SPurity:99.36%Color and Shape:SolidMolecular weight:487.57COTI-219
CAS:<p>COTI-219 is an oral inhibitor of KRAS with antitumor properties [1].</p>Formula:C17H18N6SColor and Shape:SolidMolecular weight:338.43Tezosentan
CAS:<p>Tezosentan is an antagonist of the endothelin receptor (pA2s: 9.5, 7.7 for ETA and ETB receptors, respectively).</p>Formula:C27H27N9O6SPurity:98%Color and Shape:SolidMolecular weight:605.63Quinapril
CAS:<p>Quinapril is an orally active, non-peptide, and non-thiol angiotensin-converting enzyme (ACE) inhibitor. It primarily blocks the conversion of angiotensin I to angiotensin II in both plasma and tissues. Upon enzymatic hydrolysis, Quinapril is converted into the pharmacologically active Quinaprilat and is effective in hypertension models.</p>Formula:C25H30N2O5Color and Shape:SolidMolecular weight:438.516Macitentan (n-butyl analogue)
CAS:<p>Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.</p>Formula:C20H21Br2N5O4SPurity:98%Color and Shape:SolidMolecular weight:587.29SD-7300
CAS:<p>SD-7300 (SC-81490) functions as an orally active inhibitor targeting MMP-2, MMP-9, and MMP-13, exhibiting potent inhibition with K_i values of 0.03, 0.01, and 0.03 nM, respectively. By inhibiting these metalloproteinases, SD-7300 effectively reduces extracellular matrix degradation by tumor cells, thereby curbing their invasion and metastasis. Additionally, this compound acts as a dose-dependent inhibitor of mouse corneal angiogenesis and prevents interleukin-1-induced degradation of bovine cartilage. SD-7300 is applicable in the study of breast cancer.</p>Formula:C21H30F3N3O7SColor and Shape:SolidMolecular weight:525.54SD-2590 HCl
CAS:<p>SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.</p>Formula:C22H26ClF3N2O7SPurity:98%Color and Shape:SolidMolecular weight:554.96Vecabrutinib
CAS:<p>Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.</p>Formula:C22H24ClF4N7O2Purity:99.74%Color and Shape:SolidMolecular weight:529.92Obicetrapib
CAS:<p>Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.</p>Formula:C32H31F9N4O5Purity:99.26% - >99.99%Color and Shape:SolidMolecular weight:722.6Aleglitazar
CAS:<p>Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.</p>Formula:C24H23NO5SPurity:99.03%Color and Shape:SolidMolecular weight:437.51Methylbis(2-pyridylethyl)amine Hydrochloride (N-Methyl-N,N-bis(2-pyridin-2-yl-ethyl)amine trihydrochloride)
CAS:<p>Compounds containing an unfused pyridine ring in the structure, nesoi</p>Formula:C15H19N3·3HClColor and Shape:Light Brown PowderMolecular weight:241.1579Apremilast R-Enantiomer
CAS:Other aromatic organo-sulfur compounds (excluding pesticides)Formula:C22H24N2O7SColor and Shape:White Off-White PowderMolecular weight:460.13042Dasatinib
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFormula:C22H26ClN7O2S·H2OMolecular weight:505.16629Rivaroxaban Open Ring ((R)-5-chloro-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C18H20ClN3O4SColor and Shape:Off-White SolidMolecular weight:409.89Chlorothiophene carboxylic acid (5-chlorothiophene-2-carboxylic acid)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C5H3ClO2SColor and Shape:Off-White Pale Yellow SolidMolecular weight:162.59 g/molN-Acetyl-L-Leucine (Acetyl-L-leucine)
CAS:Acyclic amides (including acyclic carbamates) and their derivatives and salts thereof, nesoiFormula:C8H15NO3Color and Shape:White PowderMolecular weight:173.10519Levetiracetam acid ((S)-2-(2-oxopyrrolidin-1-yl)butanoic acid)
CAS:<p>Lactams, nesoi</p>Formula:C8H13NO3Color and Shape:Off-White SolidMolecular weight:171.08954Atazanavir Benzylidenehydrazine Carbamate (Methyl [(S)-1-{[(2S,3S)-3-hydroxy-1-phenyl-4-{1-[4-(pyridin-2-yl)benzyl]-2-[4-(pyridin-2-yl)benzylidene]hydrazinyl}butan-2-yl]amino}-3,3-dimethyl-1-oxobutan-2-yl]carbamate)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C42H46N6O4Color and Shape:Light Yellow SolidMolecular weight:698.35805Dasatinib Related Compound A
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFormula:C22H26ClN7O3SMolecular weight:503.15064Ezetimibe Desfluoroaniline Analog ((3R,4S)-3-[(S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one)
CAS:Lactams, nesoiFormula:C24H22FNO3Color and Shape:White Off-White PowderMolecular weight:391.15837Ezetimibe 2-Fluorobenzene Isomer ((3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(2-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one)
CAS:Lactams, nesoiFormula:C24H21F2NO3Color and Shape:White Off-White SolidMolecular weight:409.14895Everolimus System Suitability Mixture (This is a mixture of Everolimus, Everolimus oxepane isomer and 9-O-Hydroxyethyl Sirolimus)
Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoiColor and Shape:White Yellow PowderSalmeterol Related Compound B (4-{1-Hydroxy-2-[6-(4-phenylbutan-2-yloxy)hexylamino]ethyl}-2-
CAS:<p>Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function</p>Formula:C25H37NO4Color and Shape:Off-White Crystalline PowderMolecular weight:415.27226Ezetimibe Ketone ((3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one)
CAS:Lactams, nesoiFormula:C24H19F2NO3Color and Shape:White SolidMolecular weight:407.1333Apremilast
CAS:Other aromatic organo-sulfur compounds (excluding pesticides)Formula:C22H24N2O7SMolecular weight:460.13042Desmethoxy Omeprazole (2-(((3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole; 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole) (DISCONTINUED)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C16H17N3O2SColor and Shape:White Off-White SolidMolecular weight:315.10415Apremilast Related Compound E
CAS:Other aromatic organo-sulfur compounds (excluding pesticides)Formula:C22H24N2O7SColor and Shape:Pale Yellow PowderMolecular weight:460.13042(4-Methylbenzoyl)trifluoroacetone (1,1,1-Trifluoro-4-hydroxy-4-(4-methylphenyl)-3-buten-2-one)
CAS:Ketones and quinones, w/not with other oxygen function,and their halogenated,sulfated,nitrated,or nitrosated derivatives, nesoiFormula:C11H9F3O2Color and Shape:White SolidMolecular weight:230.05546Methoxyamiodarone ([2-[(1RS)-1-Methoxybutyl]benzofuran-3-yl][4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone) (DISCONTINUED)
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormula:C26H31I2NO4Color and Shape:Colorless GelMolecular weight:675.03425N-Nitroso Dabigatran Etexilate Solution (1 mL ) (ethyl 3-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl)(nitroso)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate)
CAS:<p>Compounds containing an unfused pyridine ring in the structure, nesoi</p>Formula:C34H40N8O6Color and Shape:Colorless LiquidMolecular weight:656.30708N-Nitroso Carvedilol Solution (1 mL ) (N-(3-((9H-carbazol-4-yl)oxy)-2-hydroxypropyl)-N-(2-(2-methoxyphenoxy)ethyl)nitrous amide)
CAS:<p>Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoi</p>Formula:C24H25N3O5Color and Shape:LiquidMolecular weight:435.17942Ezetimibe Tetrahydropyran Analog ((2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide)
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormula:C24H21F2NO3Color and Shape:White Off-White SolidMolecular weight:409.14895(-)-3,4-Dihydroxynorephedrine
CAS:Formula:C9H13NO3Purity:98%Color and Shape:SolidMolecular weight:183.2044Ref: 4Z-P-196057
Discontinued productRef: 4Z-R-1410
Discontinued productRef: 4Z-V-0250
Discontinued productRef: 4Z-A-8445
Discontinued productRef: 4Z-T-0336
Discontinued productRef: 4Z-M-2619
Discontinued productRef: 4Z-E-1041
Discontinued productRef: 4Z-L-4255
Discontinued productRef: 4Z-A-494
Discontinued productRef: 4Z-V-0272
Discontinued productRef: 4Z-R-1420
Discontinued productRef: 4Z-F-1941
Discontinued productRef: 4Z-P-5552
Discontinued productRef: 4Z-P-139055
Discontinued productXibornol
CAS:<p>Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性,可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。</p>Formula:C18H26OColor and Shape:SolidMolecular weight:258.4Ref: TM-T35177
Discontinued productRef: 4Z-S-0517
Discontinued productRef: 4Z-M-5327
Discontinued productUlifloxacin
CAS:<p>Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.</p>Formula:C16H16FN3O3SColor and Shape:SolidMolecular weight:349.38Ref: 4Z-D-239001
Discontinued productRef: 4Z-C-0345
Discontinued productRef: 4Z-E-3417
Discontinued productIndoxacarb
CAS:<p>Indoxacarb is an Oxadiazine insecticide.</p>Formula:C22H17ClF3N3O7Purity:98%Color and Shape:SolidMolecular weight:527.83Ref: 4Z-F-222069
Discontinued productRef: 4Z-P-2683
Discontinued productRef: 4Z-P-202002
Discontinued productRef: 4Z-F-222062
Discontinued productRef: 4Z-B-3725
Discontinued productRef: 4Z-Z-039138
Discontinued productRef: 4Z-I-053110
Discontinued productRef: 4Z-I-454
Discontinued productRef: 4Z-T-0533
Discontinued productRef: 4Z-B-2842
Discontinued productRef: 4Z-F-1840
Discontinued productRef: 4Z-D-3557
Discontinued productNicorandil Impurity 9
CAS:Formula:C10H12N4O7Color and Shape:White To Off-White SolidMolecular weight:300.23Ref: 4Z-N-0515
Discontinued productRef: 4Z-P-196099
Discontinued productRef: 4Z-I-0241
Discontinued productBalsalazide Impurity 6
CAS:Formula:C20H19N6O6·ClColor and Shape:Dark Orange SolidMolecular weight:439.41 35.45Ref: 4Z-B-3014
Discontinued productRef: 4Z-P-0526
Discontinued productRef: 4Z-P-1215
Discontinued productRef: 4Z-I-124036
Discontinued productRef: 4Z-R-2959
Discontinued productRef: 4Z-V-0249
Discontinued productRef: 4Z-P-142158
Discontinued productKetamine EP Impurity A (E-Isomer) HCl (Ketamine USP Related Compound A (E-Isomer) HCl)
CAS:Formula:C13H16ClNO·HClColor and Shape:White To Off-White SolidMolecular weight:237.73 36.46Ref: 4Z-K-018001
Discontinued product4-Hydroxy-N-Desmethyl Tamoxifen-d5 (Endoxifen-d5) (Mixture of Z and E Isomers)
CAS:Formula:C25H22D5NO2Color and Shape:White To Off-White SolidMolecular weight:378.53Ref: 4Z-T-0113
Discontinued productRef: 4Z-T-81202
Discontinued productRef: 4Z-D-237011
Discontinued productRef: 4Z-N-1788
Discontinued productRef: 4Z-E-4345
Discontinued productRef: 4Z-R-2960
Discontinued productRef: 4Z-M-269056
Discontinued productRef: 4Z-A-10111
Discontinued productRef: 4Z-E-4344
Discontinued productRef: 4Z-L-1796
Discontinued productRef: 4Z-T-4965
Discontinued productRef: 4Z-T-476
Discontinued productRef: 4Z-P-368025
Discontinued productRef: 4Z-F-1838
Discontinued productRef: 4Z-O-0889
Discontinued productRef: 4Z-N-148006
Discontinued productRef: 4Z-B-153007
Discontinued productRef: 4Z-A-238005
Discontinued productRef: 4Z-Q-0170
Discontinued productRef: 4Z-B-4366
Discontinued productRef: 4Z-T-4971
Discontinued productRef: 4Z-M-269015
Discontinued productBupropion Impurity ((3R,5RS,6RS)-6-(3-Chlorophenyl)-6-Hydroxy-5-Methyl-3-Thiomorpholine Carboxylic Acid)
Formula:C12H14ClNO3SMolecular weight:287.77Ref: 4Z-B-0516
Discontinued productRef: 4Z-N-0519
Discontinued productRef: 4Z-L-4429
Discontinued productRef: 4Z-T-4946
Discontinued productRef: 4Z-S-1748
Discontinued productRef: 4Z-N-4868
Discontinued productRef: 4Z-P-5549
Discontinued productRef: 4Z-K-031119
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Discontinued productRef: 4Z-L-4238
Discontinued productRef: 4Z-N-1740
Discontinued productRef: 4Z-T-10150
Discontinued productRef: 4Z-E-1018
Discontinued productRef: 4Z-I-066015
Discontinued productRef: 4Z-B-0823
Discontinued productRef: 4Z-N-0513
Discontinued productRef: 4Z-B-115040
Discontinued productTadalafil Impurity 98
CAS:Formula:C23H23ClN4O4Color and Shape:White To Off-White SolidMolecular weight:454.91Ref: 4Z-T-10147
Discontinued productRef: 4Z-V-2513
Discontinued productRef: 4Z-C-797
Discontinued productRef: 4Z-T-8133
Discontinued productRef: 4Z-R-139065
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Discontinued productRef: 4Z-N-0544
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Discontinued productRef: 4Z-L-190001
Discontinued productRef: 4Z-S-4145
Discontinued productRef: 4Z-R-4012
Discontinued product1E,3Z,5E,7E-Indocyanine Green Impurity 23 Sodium Salt
Formula:C42H46N2O6S2·NaMolecular weight:738.96 22.99Ref: 4Z-I-134030
Discontinued productRef: 4Z-T-184011
Discontinued productRef: 4Z-P-181013
Discontinued productRef: 4Z-B-154015
Discontinued product1E,3Z,5E,7Z-Indocyanine Green Impurity 23 Sodium Salt
Formula:C42H46N2O6S2·NaMolecular weight:738.96 22.99Ref: 4Z-I-134031
Discontinued productRef: 4Z-P-5317
Discontinued productRef: 4Z-S-06141
Discontinued productRef: 4Z-I-0214
Discontinued productRef: 4Z-V-098
Discontinued productRef: 4Z-N-066022
Discontinued productRef: 4Z-T-117132
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Discontinued productRef: 4Z-B-1752
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Discontinued productRef: 4Z-N-3138
Discontinued productAmantadine-d6 (1-Amino Adamantane-d6)
CAS:Formula:C10H11D6NColor and Shape:Off-White SolidMolecular weight:157.29Ref: 4Z-A-612
Discontinued productMMP13-IN-2
CAS:<p>MMP13-IN-2 is a highly potent, selective, and orally active inhibitor of MMP-13. It demonstrates exceptional potency against MMP-13, with an IC50 value of 0.036 nM, and exhibits selectivities greater than 1,500-fold over MMP-1, 3, 7, 8, 9, 14, and TACE. Moreover, MMP13-IN-2 possesses the capability to effectively inhibit collagen release from cartilage in vitro. Consequently, MMP13-IN-2 holds great potential for advancing research on collagenase-related diseases.</p>Formula:C24H19FN6O4SColor and Shape:SolidMolecular weight:506.51Ref: 4Z-E-26116
Discontinued productRef: 4Z-V-091008
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Discontinued productRef: 4Z-E-4841
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Discontinued productRef: 4Z-I-061019
Discontinued productRef: 4Z-K-031142
Discontinued productRef: 4Z-B-230001
Discontinued productRef: 4Z-B-1643
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Discontinued productRef: 4Z-E-1040
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Discontinued productRef: 4Z-S-0522
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Discontinued productRef: 4Z-O-0333
Discontinued productRef: 4Z-B-432
Discontinued productRef: 4Z-R-107015
Discontinued productRef: 4Z-O-02101
Discontinued productRef: 4Z-T-10148
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Discontinued productRef: 4Z-C-0129
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