Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65562 products of "Quinazoline and Quinoline Derivatives"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Tianeptine
CAS:<p>Applications Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant.<br>References Malen, C., et al.: Experientia, 28, 811 (1972), Safa, A., et al.: J. Biol. Chem., 262, 7884 (1987), Ford, J.M., et al.: Pharmacol. Rev., 42, 155, (1990), Pierre, A., et a.: Cancer Res., 51, 2312 (1991),<br></p>Formula:C21H25ClN2O4SColor and Shape:White To Off-WhiteMolecular weight:436.95Rilpivirine
CAS:Controlled Product<p>Applications A novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.<br>References Sun, et al.: J. Med. Chem., 41, 4648 (1998), Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (2001),<br></p>Formula:C22H18N6Color and Shape:YellowMolecular weight:366.42Propentofylline
CAS:Controlled ProductFormula:C15H22N4O3Color and Shape:White To Off-WhiteMolecular weight:306.36Desmethyl Mirtazapine Dihydrochloride
CAS:<p>Applications A metabolite of Mirtazapine, α2-adrenergic blocker.<br>References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990)<br></p>Formula:C16H19Cl2N3Color and Shape:White To Off-WhiteMolecular weight:324.25Valsartan-d9 (Major)
CAS:Controlled Product<p>Applications An isotopically labelled version of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Formula:C24H20D9N5O3Color and Shape:Off WhiteMolecular weight:444.57(R)-Tamsulosin-d4 Hydrochloride
CAS:Controlled Product<p>Applications (R)-Tamsulosin-d4 Hydrochloride is the labeled analogue of (R)-Tamsulosin Hydrochloride (T006350), a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.<br>References Kawabe, K., et al.: J. Urol., 144, 908 (1990); Abrams, P., et al.: Br. J. Urol., 76, 325 (1995); Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004)<br></p>Formula:C20H25D4ClN2O5SColor and Shape:NeatMolecular weight:449.0Quinoxyfen
CAS:Controlled Product<p>Applications Agricultural fungicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Corrales, M., et al.: Food Chem. Toxicol., 48, 3471 (2010), Lagunas-Allue, L., et al.: Anal. Bioanal. Chem., 398, 1509 (2010), Wong, J., et al.: J. Agric. Food Chem., 58, 5897 (2010),<br></p>Formula:C15H8Cl2FNOColor and Shape:Off-WhiteMolecular weight:308.13N1,N3-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N1,N3-dimethyl-1,3-propanediamine Dihydrochloride
CAS:Controlled Product<p>Impurity Verapamil EP Impurity A DIHCL<br>Stability Hygroscopic<br>Applications N1,N3-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N1,N3-dimethyl-1,3-propanediamine Dihydrochloride (Verapamil EP Impurity A DIHCL) is an impurity of Verapamil (V125000), a calcium channel blocker. Antihypertensive; antianginal; antiarrhythmic (class IV).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Atlas, D, and Adler, M.: Proc. Natl. Acad. Sci. USA, 78, 1237 (1981), Janis, R., et al.: Adv. Drug. Res., 16, 309 (1987)<br></p>Formula:C25H38N2O4·2ClHColor and Shape:NeatMolecular weight:503.51Deoxy Epinephrine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Andregenic and dopamine receptor agonist; active metabolite of Ibopramine (I123500). Also, it is used as internal standard in chromatographic analysis of catecholamines.<br>References Kindler, P., et al.: Arch. Pharm., 270, 340 (1932), Bridgers, W.F., et al.: J. Biol. Chem., 237, 526 (1962),<br></p>Formula:C9H13NO2·ClHColor and Shape:Light Brown To PurpleMolecular weight:203.67Ethyl Difluoroacetate
CAS:Controlled Product<p>Applications Ethyl difluoroacetate<br></p>Formula:C4H6F2O2Color and Shape:NeatMolecular weight:124.09Celecoxib-d4
CAS:Controlled Product<p>Applications A labelled selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in the treatment of familial adenomatous polyposis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Formula:C17H10D4F3N3O2SColor and Shape:White To Light YellowMolecular weight:385.43-(3,4-dimethylphenyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one
CAS:Purity:98%Molecular weight:282.3599853515625N-Nitroso Clonidine
CAS:Controlled ProductFormula:C9H8Cl2N4OColor and Shape:NeatMolecular weight:259.09Dimetridazole-d3
CAS:Controlled Product<p>Applications Labelled Dimetridazole (D479660). An antihistomonal agent. Antiprotozoal (Histomonas).<br>References Butler, K., et al.: J. Med. Chem., 10, 891 (1967), Mitrovic, M., et al.:; Antimicrob. Agents Chemother., 445, 1968, Mitrovic, M., et al.: Poult. Sci., 49, 86 (1970),<br></p>Formula:C52H3H4N3O2Color and Shape:Off-WhiteMolecular weight:144.15Retigabine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A new experimental anticonvulsant drug. Anxiolytic.<br>References Dailey, J.W.; et al.: Neuroscience Lett., 195, 77 (1995), Korsgaard, M.P.G., et al.: J. Pharmacol. Exp. Ther., 314, 1, 282 (2005),<br></p>Formula:C16H18FN3O2Color and Shape:NeatMolecular weight:303.333-Phenyl-1-propanol
CAS:Controlled Product<p>Impurity Alverine EP Impurity B<br>Applications 3-Phenyl-1-propanol is used as a reagent in the synthesis of Dihydrocinnamyl Cilnidipine (D448605) and is a potent aroma biotransformation product.<br>References Bosse, A.K., et al.: Food Chem., 141, 2952 (2013)<br></p>Formula:C9H12OColor and Shape:ColourlessMolecular weight:136.19rac-5-Bromo Naproxen
CAS:Controlled ProductFormula:C14H13BrO3Color and Shape:NeatMolecular weight:309.164-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-ol
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:328.375Empagliflozin (Tetrahydrofuranyl-d4)
CAS:Controlled Product<p>Applications Empagliflozin-d4 is a labelled analog of Empagliflozin (E521510); a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats.<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Formula:C23D4H23ClO7Color and Shape:NeatMolecular weight:454.934Ethosuximide-d3
CAS:Controlled ProductFormula:C7H8D3NO2Color and Shape:White To Light YellowMolecular weight:144.192-Amino-4-(4-isopropyl-phenyl)-thiophene-3-carboxylic acid amide
CAS:Formula:C14H16N2OSPurity:97%Color and Shape:SolidMolecular weight:260.36N-methoxy-N-methyl-2-phenylquinoline-4-carboxamide
CAS:Purity:95.0%Molecular weight:292.3380126953125Bis(2-aminoethylthio)methane Dihydrochloride
CAS:Controlled Product<p>Applications Bis(2-aminoethylthio)methane is a potential inhibitor of γ-glutamylcysteine synthetase, the first enzyme in the glutathione biosynthesis pathway.<br>References Sweetman, B.J., et al.: J. Med. Chem., 12, 888 (1969); Seelig, G.F., et al.: J. Biol. Chem., 259, 3534 (1984);<br></p>Formula:C5H14N2S2·2(HCl)Color and Shape:NeatMolecular weight:239.22Empagliflozin α-Anomer
CAS:Controlled ProductFormula:C23H27ClO7Color and Shape:White To Off-WhiteMolecular weight:450.909Nitisinone
CAS:<p>Applications Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I.<br>References Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998),<br></p>Formula:C14H10F3NO5Color and Shape:NeatMolecular weight:329.23Lansoprazole
CAS:<p>Applications Used as a gastric proton pump inhibitor. An antiulcerative. May limit the severity of tuberculosis (see Chem. and Eng. News. p. 28 July 20 (2018)).<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006), Chem. and Eng. News. p. 28 July 20 (2018)<br></p>Formula:C16H14F3N3O2SColor and Shape:White To Light BeigeMolecular weight:369.36(R)-Timolol
CAS:Controlled Product<p>Impurity Timolol EP Impurity A; Timolol BP Impurity A; Timolol USP Related Compound A<br>Applications (R)-Timolol (Timolol EP Impurity A; Timolol BP Impurity A; Timolol USP Related Compound A) is an antihypertensive agent that increases ocular blood flow and reduces intraocular pressure. (R)-Timolol is an β-adrenergic blocking agent that binds only to nonspecific sites in the particulate fraction of the heart, lungs, and brain.<br>References Rotmensch, H. et al.: J. Clinical. Pharmacol., 33, 544 (1993); Chiou, G. & Chen. Y., J. Ocular. Pharmacol., 8, 183 (1992); Chiou, G. et al.: J. Ocular. Pharmacol., 6, 23 (1990); Tocco, D. et al.: Drug Met. Disposit., 4, 323 (1976)<br></p>Formula:C13H24N4O3SColor and Shape:NeatMolecular weight:316.42(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)
CAS:Controlled Product<p>Applications (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) (CAS# 1395950-84-1) is a useful isotopically labeled research compound.<br></p>Formula:C21D5H17Cl2FN5OColor and Shape:NeatMolecular weight:455.3675Tolvaptan-d7
CAS:Controlled Product<p>Applications Labelled Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).<br>References Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000), Udelson, J., et al.: Circulation, 104, 2417 (2001), Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005), Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006),<br></p>Formula:C26H18D7ClN2O3Color and Shape:NeatMolecular weight:455.98N'-[thien-2-ylmethylene]imidazo[1,2-a]pyridine-7-carbohydrazide
CAS:Molecular weight:270.309997558593752-Chloro-5-fluoro-3,8-dimethylquinoline
CAS:Formula:C11H9ClFNPurity:95.0%Color and Shape:SolidMolecular weight:209.651-N-Boc-4-(4-Pyridylmethylamino)piperidine
CAS:Formula:C16H25N3O2Purity:98.0%Color and Shape:Solid, No data available.Molecular weight:291.395N-(2,3-Dichlorophenyl)piperazine Hydrochloride
CAS:Controlled ProductFormula:C10H12Cl2N2·ClHColor and Shape:WhiteMolecular weight:267.584-Anilino-4-oxobutanoic Acid
CAS:Controlled Product<p>Applications The metabolite (MII) of Suberoylanilide Hydroxamic Acid (S688700).<br>References Sun, W.S., et al.: J. Med. Chem., 46, 5619 (2003)<br></p>Formula:C10H11NO3Color and Shape:NeatMolecular weight:193.20Agomelatine Dimer Urea
CAS:<p>Impurity Agomelatine Impurity 4<br>Applications Agomelatine Dimer Urea is an impurity of Agomelatine (A430020). Agomelatine Impurity 4<br>References Depreux, P., et al.: J. Med. Chem., 37, 3231 (1994); Wregget, K., et al.: J. Biol. Chem., 270, 22488 (1995); Ying, S., et al.: Eur. J. Pharmacol., 296, 33 (1996);<br></p>Formula:C27H28N2O3Color and Shape:NeatMolecular weight:428.52Aripiprazole N4-Oxide
CAS:Controlled Product<p>Impurity Aripiprazole Impurity 9<br>Applications Aripiprazole N4-Oxide is a metabolite of anti-psychotic drug, Aripiprazole (A771000). Aripiprazole Impurity 9<br>References Rowley, M., et al.: J. Med. Chem., 44, 477 ( 2001), Ozdemir, V., et al.: Curr. Opin. Invest Drugs 2002, 3, 113,,,4) Jordan, S; European Journal Pharmacol 2002, 441, 137<br></p>Formula:C23H27Cl2N3O3Color and Shape:NeatMolecular weight:464.38Niclosamide Monohydrate
CAS:Controlled ProductFormula:C13H8Cl2N2O4·H2OColor and Shape:WhiteMolecular weight:345.1352-[5-bromo-2-(pyridin-2-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Purity:95.0%Molecular weight:352.6600036621094(1S,2S,3R,5S)-3-[[3-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-yl]amino]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
CAS:Controlled ProductFormula:C23H28F2N6O4SColor and Shape:NeatMolecular weight:522.573-Picoline
CAS:Controlled Product<p>Applications A useful precursor to agrochemicals and antidotes for organophosphate poisoning.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Qiao, L., et al.: Bioorg. Med. Chem. Lett., 19, 6122 (2009), Giri, A., et al.: Food Chem., 120, 621 (2010), Farrer, N., et al.: Chem. Res. Toxicol., 23, 413 (2010),<br></p>Formula:C6H7NColor and Shape:ColourlessMolecular weight:93.132-[-2[(5-Nitro-2-furanyl)methylene]hydrazinyl]acetic Acid
CAS:Controlled Product<p>Applications 2-[-2[(5-Nitro-2-furanyl)methylene]hydrazinyl]acetic Acid is an impurity of Nitrofurantoin (N493850), a nitrofuran antibiotic with low resistance potential that is rapidly metabolized by mammals.<br>References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976); Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004);<br></p>Formula:C7H7N3O5Color and Shape:NeatMolecular weight:213.1483-Hydroxyagomelatine
CAS:<p>Impurity Agomelatine Impurity 11/ Agomelatine 3-Hydroxy Impurity<br>Applications 3-Hydroxyagomelatine is an intermediate in the synthesis of 1-(aminoethyl)naphthalene derivative with potential binding affinity for melatonin receptors. Agomelatine Impurity 11<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simonin, G., et al.: J. Pharma. Biomed. Anal., 21, 591 (1999)<br></p>Formula:C15H17NO3Color and Shape:NeatMolecular weight:259.3(3-Cyclohexyl)propyl 5-(1,3-dioxolan-2-yl)-2-thienyl ketone
CAS:Purity:97.0%Molecular weight:308.440002441406254,4',4''-(2,4,6-Trimethylbenzene-1,3,5-triyl)tripyridine
CAS:Purity:97%Molecular weight:351.453002929687510-Oxo Mirtazapine (Mirtazapine Impurity F)
CAS:Controlled Product<p>Impurity Mirtazapine EP Impurity F<br>Applications 10-Oxo Mirtazapine (Mirtazapine Impurity F) is an impurity of Mirtazapine. Mirtazapine EP Impurity F.<br>References De Boer, T., et al.: Neuropharmacol., 27, 399 (1988), Vindevogel, J., et al.: Anal. Chem., 63, 1530 (1991), Wynia, G., et al.: J. Chromatogr., 773, 339 (1997),<br></p>Formula:C17H17N3OColor and Shape:NeatMolecular weight:279.34(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride
CAS:Controlled Product<p>Applications (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate used to prepare trans-2-arylcyclopropylamines as potent and selective dipeptidyl peptidase IV inhibitors.<br>References Tsai, T., et al.: Bioorg. Med. Chem., 17, 2388 (2009)<br></p>Formula:C9H9F2N·HClColor and Shape:Off White SolidMolecular weight:205.632
![N1,N3-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N1,N3-dimethyl-1,3-propanediamine Dihydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FB429915.webp&w=3840&q=75)
![4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-ol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF321517.webp&w=3840&q=75)
![N'-[thien-2-ylmethylene]imidazo[1,2-a]pyridine-7-carbohydrazide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF518016.webp&w=3840&q=75)
![2-[5-bromo-2-(pyridin-2-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF526132.webp&w=3840&q=75)
![(1S,2S,3R,5S)-3-[[3-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]-5-(propylthio)-3H-1,2,3-triazolo[4…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD445335.webp&w=3840&q=75)
![2-[-2[(5-Nitro-2-furanyl)methylene]hydrazinyl]acetic Acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FN495910.webp&w=3840&q=75)
![1-[6-(5-Amino-2-methylphenoxy)-3-pyridinyl]ethanone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF609734.webp&w=3840&q=75)
